Clinical trials: Cancer of Prostate
Cancer of Prostate
De-implementation of Low Value Castration for Men With Prostate Cancer
This study will use a theory-based, mixed methods approach to identify, tailor and pilot two different de-implementation strategies that vary widely in delivery, impact, and expected results for reducing low value androgen…
- Trial name
- DeADT (NCT03579680)
- Testing
- ADT ORDER CHECK ATTESTATION (OR), PROVIDER SCRIPT (SC)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Prostate Cancer
Patient and Provider Perspectives on Genetic Risk Profiling
A qualitative interview study exploring the patient and provider perspectives on the clinical utility of genetic risk profiling in routine clinical practice.
- Trial name
- PPP (NCT07741929)
- Testing
- Qualitative interview
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Prostate Cancer
Update and Biodistribution of [F-18]FMDHT pET/CT in Normal Healthy Volunteers and Patients With Metastatic Prostate Cancer - A First in Human Subject Study With [F-18] FMDHT
Prostate cancer represents a significant health problem in the United States. This year 179,000 men in the United States will be diagnosed with prostate carcinoma and approximately 25% of them will die of the disease.
- Trial name
- NCT01724619
- Testing
- [F-18] fluorinated dihydrotestosterone (FDHT)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Prostate Cancer
Prostate Cancer Screening With Abbreviated MRI Protocol
Prostate cancer is one of the most common malignancies in the male population with incidence and mortality rates comparable to breast cancer in women, but in contrast, a population screening program that would fulfill all the…
- Trial name
- ProstaPilot (NCT05603351)
- Testing
- magnetic resonance, serum PSA examination, Biopsy
- Where
- Czechia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Masaryk Memorial Cancer Institute
Neoplams, Prostate Cancer (Adenocarcinoma)
Pilot Feasibility Study of a Dyadic Culinary Nutrition Intervention
This study will determine the feasibility and acceptability of a 12-week dyadic culinary nutrition program among Hispanic prostate cancer survivor/caregiver dyads using a randomized controlled trial design.
- Conditions
- Neoplams, Prostate Cancer (Adenocarcinoma), Cancer Survivors, Caregiver Burden
- Trial name
- CHEF (NCT07702864)
- Testing
- Cooking Healthy - Engaging Families (CHEF), Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Prostatic Neoplasm
Pd-103 Dose De-Escalation for Early Stage Prostate Cancer: A Prospective Randomized Trial
The purpose of this study is to determine the most appropriate radiation implant dose for palladium-103 monotherapy. Radiation dose is related to potential cure.
- Trial name
- NCT00247312
- Testing
- Pd-103
- Where
- 2 sites in United States
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Schiffler Cancer Center
Prostate Cancer, Carcinoma of the Rectum
Minocycline Attenuate Postoperative Cognitive Dysfunction and Delirium
Postoperative cognitive dysfunction (POCD) and postoperative delirium occurs mainly in aged patients. POCD and POD may increase the mortality and morbidity.
- Conditions
- Prostate Cancer, Carcinoma of the Rectum, Colon Cancer, Renal Carcinoma
- Trial name
- MAPOCD (NCT02928692)
- Testing
- Minocycline
- Where
- 5 sites in China
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Prostate Cancer
Goals of Sexual Function in Prostate Cancer Survivors and Their Partners After Cancer Treatment
RATIONALE: Gathering information about survivors of prostate cancer and their partners may help doctors learn more about the goals for sexual functioning after cancer treatment.
- Trial name
- NCT01018901
- Testing
- Survey Administration
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Prostate Cancer
Veteran Peer Navigators to Promote Shared Decision Making for PSA Screening
The project will investigate the efficacy of a Veteran-peer-navigator-led decision coaching (PDC) program to promote Shared Decision Making (SDM) for prostate cancer screening among Veterans at the Veterans Health Administration…
- Trial name
- NCT06549036
- Testing
- Veteran Peer Decision Coaching Session for PSA Screening
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Prostate Cancer, Anesthesia
Low-flow Versus Minimal-flow Sevoflurane Anesthesia During Robot-assisted Laparoscopic Radical Prostatectomy
Study Synopsis This protocol is formatted for ClinicalTrials.gov-style registration and manuscript-facing documentation. It is based on the uploaded Turkish ethics protocol and keeps the original core design: comparison of…
- Conditions
- Prostate Cancer, Anesthesia, Respiratory Mechanics
- Trial name
- NCT07475533
- Testing
- Common Anesthetic Management
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Precancerous Condition, Prostate Cancer
Fish Oil and Green Tea Extract in Preventing Prostate Cancer in Patients Who Are at Risk for Developing Prostate Cancer
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of fish oil and/or green tea may prevent prostate cancer.
- Trial name
- NCT00253643
- Testing
- green tea catechin extract, fish oil
- Where
- 3 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Prostate Cancer
Prostate Cancer Diagnosis Through NMR Spectroscopy of Semen and Prostatic Secretions
To develop the hypothesis that quantitative NMR spectroscopy of human semen can be used to diagnose prostate cancer.
- Trial name
- NCT00250757
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- New Mexico Cancer Research Alliance
Prostate Cancer
Clinical Validation of a Urinary Exosome Gene Signature in Men Presenting for Suspicion of Prostate Cancer
Validate a non-DRE exosome gene expression test, with an NPV >/= 90% certainty, will exclude the presence of high gleason grade/ score (>/=7) prostate cancer in a prostate needle biopsy.
- Trial name
- NCT02702856
- Testing
- ExoIntelliScore Prostate
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Exosome Diagnostics, Inc.
Thoracic Cancer, Ovarian Cancer
Project CADENCE (CAncer Detected Early caN be CurEd)
With existing evidence showing the difference in miRNA expression levels between non-cancer and cancer groups, the investigators assume that levels of DNA methylation, RNA expression as well as protein concentration will also be…
- Conditions
- Thoracic Cancer, Ovarian Cancer, Liver Cancer, Prostate Cancer
- Trial name
- CADENCE (NCT05633342)
- Where
- Singapore
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- MiRXES Pte Ltd
Prostate Cancer, Creative Arts Therapy
Creative Arts Therapy on Body Image, Self-esteem, Anxiety and Depression in Post-Treatment Prostate Cancer Patients
The goal of this clinical study is to assess the feasibility of implementing a creative arts therapy intervention of drawing and painting in Hong Kong prostate cancer patients and preliminarily examine the effects of this…
- Trial name
- NCT07015866
- Testing
- Guided therapy group, Creative arts therapy
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Prostate Cancer
Artificial Intelligence and Radiologists at Prostate Cancer Detection in MRI: The PI-CAI Challenge
The PI-CAI challenge aims to validate the diagnostic performance of artificial intelligence (AI) and radiologists at clinically significant prostate cancer (csPCa) detection/diagnosis in MRI, with respect to histopathology and…
- Trial name
- NCT05489341
- Testing
- Histopathology and Magnetic Resonance Imaging with Follow-Up, Histopathology and Magnetic Resonance Imaging
- Where
- Netherlands
- Volunteers
- 10,207 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Prostate Cancer Cured, Healthy Population Control
Study of Geriatric Patients Aged 75 Years or Older Treated and Cured for Localized Prostate Cancer: Case-control Study
This is a multicenter pilot study, proposed for cases and controls 3 departments in France. Cases are cured patients who have had prostate cancer for at least 10 years.
- Trial name
- PROGE (NCT01797692)
- Testing
- geriatric assessment
- Where
- 5 sites in France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Centre Francois Baclesse
Prostate Cancer
Understanding of Genetics by Men at Risk for Prostate Cancer
With this greater certainty regarding prognosis, men with localized prostate cancer are now equipped with make better treatment planning decisions.
- Trial name
- NCT04550845
- Testing
- Focus group analyses
- Where
- 3 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Prostate Cancer, Treatment
Comparison H-FIRE and Laparoscopic RP in Treating Men With Localized Prostate Cancer
This trial is comparing the functional and oncological outcomes in treating men with prostate cancer between high-frequency irreversible electroporation and laparoscopic radical prostatectomy.
- Trial name
- NCT04278261
- Testing
- Focal therapy(high-frequency irreversible electroporation), laparoscopic radical prostatectomy
- Where
- China
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Shanghai East Hospital
Prostate Cancer XXX, TRANSRECTAL ULTRASOUND-GUIDED PROSTATE BIOPSY
Effect of Lidocaine Gel and Cold Lidocaine Gel on Pain in Patients Who Had Prostate Biopsy With Transrectal Ultrasound
Prostate cancer is one of the most common types of malignancy in men. Transrectal ultrasound-guided prostate biopsy (TRUSG-PBx) is considered the current gold standard method in the diagnosis of prostate cancer.
- Trial name
- NCT06429046
- Testing
- LIDOCAINE GEL, COLD LIDOCAINE GEL
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cukurova University