Clinical trials: Cancer-Associated Pain
Cancer Pain, Cancer
PARASTOP - Paracetamol With Strong Opioids
Current guidelines recommend all people with cancer-related pain should be prescribed paracetamol, even those receiving high doses of strong pain killers (opioids) such as morphine.
- Trial name
- PARASTOP (NCT05051735)
- Testing
- Paracetamol
- Where
- 15 sites in Italy, Norway and 2 more
- Volunteers
- 204 people
- Sponsor
- Oslo University Hospital
Abdominal Cancer, Cancer Pain
Permanent Celiac Plexus Block: Comparison of Pain Score in Unilateral and Bilateral Posterior Percutaneous Approach
The goal of this prospective, interventional, non-randomized study was to compare pain score in unilateral and bilateral posterior percutaneous neurolytic celiac plexus block (NCPB) in upper abdominal cancer patients.
- Conditions
- Abdominal Cancer, Cancer Pain, Cancer of Pancreas
- Trial name
- NCT06316908
- Testing
- Unilateral Neurolytic Celiac Plexus Block with Absolute Alcohol, Bilateral Neurolytic Celiac Plexus Block with Absolute Alcohol
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Sindh Institute of Urology and Transplantation
Hematopoietic/Lymphoid Cancer, Pain
Opioids With or Without Olanzapine in Treating Patients With Moderate to Severe Cancer Pain
RATIONALE: Opioids lessen pain caused by cancer. It is not yet known whether opioids are more effective when given together with or without olanzapine in treating cancer pain.
- Conditions
- Hematopoietic/Lymphoid Cancer, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00737191
- Testing
- olanzapine
- Sponsor
- Mayo Clinic
Cancer Pain
Endovascular Denervation in Patients With Cancer Pain
Endovascular arterial denervation (ED) is a minimally invasive technique which could reduce the occurrence of injury of visceral tissue or organs.
- Trial name
- NCT03431922
- Testing
- endovascular denervation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Zhongda Hospital
Pain
Conversion From Fast Acting Oral Opioids to Abstral®
The purpose of this study is to evaluate safety and efficacy when using a novel dose conversion strategy to switch from immediate release oral opioids to sublingual (SL) fentanyl (Abstral) for treatment of breakthrough cancer…
- Trial name
- NCT01315886
- Testing
- SL fentanyl
- Where
- Sweden
- Volunteers
- 8 people
- Sponsor
- Orexo AB
Breast Cancer
Yoga for Aromatase Inhibitor-associated Joint Pain
The purpose of this study is to determine whether it might be practical and useful to investigate the effectiveness of yoga classes in relieving joint pain associated with the use of a class of medications known as aromatase…
- Trial name
- NCT01951976
- Testing
- Questionnaires, Yoga Classes
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Pain, Chronic, Cancer Pain
Telemedicine Versus In-Person Follow-up for Cancer Pain Management: An Equity and Cost Analysis Comparison Using a Prospective Quasi-Experimental Design
Cancer is the second leading cause of death worldwide, with approximately 18.1 million new cases and 9.6 million deaths reported in 2018.
- Conditions
- Pain, Chronic, Cancer Pain, Cancer Related Pain
- Trial name
- NCT05628246
- Testing
- Telemedicine, In-person
- Where
- Thailand
- Volunteers
- 193 people
- Sponsor
- Mahidol University
Quality of Life, Chronic Cancer Pain
Effect of Patient-Controlled Transcutaneous Electrical Acupoint Stimulation on Quality of Life in Chronic Cancer Pain
This study aims to objectively evaluate the effect of Patient-Controlled Transcutaneous Electrical Acupoint Stimulation (PC-TEAS) on improving the quality of life in patients with chronic cancer pain, thereby providing…
- Trial name
- NCT07308951
- Testing
- TEAS
- Where
- China
- Volunteers
- 290 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Peripheral Neuropathic Pain, Neurotoxicity
Molecular-Genetic Mechanisms Associated With Chemotherapy-Induced Nerve Damage
Background: Docetaxel, the most commonly used drug for the treatment of invasive breast cancer, has been shown to prolong the lives of women with breast cancer and prevent the cancer from spreading or returning.
- Conditions
- Peripheral Neuropathic Pain, Neurotoxicity, Cancer
- Trial name
- NCT01293851
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Institute of Nursing Research (NINR)
Breast Neoplasms
The Use of Pentoxifylline and Vitamin E in the Treatment of Chronic Breast Pain
An estimated 20 - 45 % of women treated with breast conserving treatment experience chronic pain in the treated breast. The aetiology of this is poorly understood. Some of these women have signs of chronic radiation mastitis.
- Trial name
- NCT00188669
- Testing
- pentoxifylline, alpha-Tocopherol
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University Health Network, Toronto
Chronic Pain, Cancer Pain
Prometra Post-Approval Study
The Prometra Pump is approved by the FDA for use in the United States. The purpose of this study is to collect long-term safety data on the Prometra Pump.
- Conditions
- Chronic Pain, Cancer Pain, Intractable Pain, Back Pain
- Trial name
- NCT01854229
- Testing
- Prometra Programmable Intrathecal Infusion Pump
- Where
- 26 sites in United States
- Volunteers
- 400 people
- Sponsor
- Flowonix Medical
Breast Neoplasm Female, Arthralgia
Trial of Oral Hyaluronic Acid for the Prevention of Aromatase Inhibitor-Associated Arthralgias
This is a single center, double-blinded, placebo-controlled, randomized Phase II trial to determine whether oral hyaluronic acid will prevent aromatase inhibitor (AI)-associated arthralgias.
- Trial name
- NCT03384095
- Testing
- Hyaluronic Acid (HA)
- Where
- 4 sites in United States
- Sponsor
- Erin Newton
Acupressure, Cancer Pain
The Effect of Acupressure and Reiki on Pain and Fatigue Levels
This research was conducted with the aim of determining the effect of levels of pain and fatigue of acupressure and Reiki application on cancer patients receiving palliative care.
- Conditions
- Acupressure, Cancer Pain, Fatigue
- Trial name
- NCT05473845
- Testing
- Acupressure intervention, Reiki intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Mardin Artuklu University
Autonomic Nervous System Imbalance, Psychological Distress
Stochastic Modulated Vibrations on Autonomic Nervous System of Breast Cancer Patients During Radiotherapy
The aim of this research is to study the influence of stochastic modulated vibrations on the autonomic nervous system of breast cancer patients during radiation therapy
- Conditions
- Autonomic Nervous System Imbalance, Psychological Distress, Cancer-related Pain, Breast Cancer Lymphedema
- Trial name
- NCT04125953
- Testing
- Andullation
- Where
- Belgium
- Volunteers
- 130 people
- Sponsor
- Universitair Ziekenhuis Brussel
Bone Metastasis, Cancer Pain
Phase 3 Study on the Efficacy and Safety of Tanezumab in Patients With Cancer Pain Due to Bone Metastasis Who Are Taking Background Opioid Therapy
The purpose of this study is to determine whether tanezumab is effective in the treatment of cancer pain due to bone metastasis in patients already taking background opioid therapy.
- Trial name
- NCT02609828
- Testing
- Tanezumab
- Where
- 89 sites in Argentina, Australia and 14 more
- Volunteers
- 156 people
- Sponsor
- Pfizer
Breast Cancer, Inflammatory Breast Cancer Stage IV
Hypnosis for Pain in Black Women With Advanced Breast Cancer: A Feasibility Study
The purpose of this study is to compare two hypnotic interventions for Black women with advanced cancer pain in preparation for a well-powered phase III study.
- Conditions
- Breast Cancer, Inflammatory Breast Cancer Stage IV, Inflammatory Breast Neoplasms, Triple Negative Breast Neoplasms
- Trial name
- NCT06057636
- Testing
- Self-Administered Hypnosis, Self-Administered White Noise Hypnosis
- Where
- United States
- Sponsor
- The University of Tennessee, Knoxville
Chronic Pain, Cancer Pain
Mindfulness-oriented Recovery Enhancement (MORE) for Cancer Pain Relief
The purpose of this study is to evaluate whether or not mindfulness-based interventions/MBIs may help reduce chronic pain in participants who have cancer-related chronic pain.
- Trial name
- NCT05877521
- Testing
- MORE treatments, Standard of Care for Pain Management
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pain, Cancer
Safety & Efficacy Study of Subcutaneous Tetrodotoxin for Moderate to Severe Inadequately Controlled Cancer-related Pain
Different pathophysiologic mechanisms are responsible for the development of chronic pain disorders. Pain pathways are triggered in part by ectopic discharges of voltage-sensitive sodium channels, which are in abundance in both…
- Trial name
- TEC-006 (NCT00725114)
- Testing
- Tetrodotoxin
- Where
- Canada
- Volunteers
- 165 people
- Sponsor
- Wex Pharmaceuticals Inc.
Cancer Pain, Erector Spinae Plane Block
Intermittent Erector Spinae Plane Block Via Subcutaneous Port for Cancer Pain
Cancer-related pain is a common and challenging problem in patients with lung cancer, often requiring long-term pain management.
- Trial name
- NCT07396558
- Testing
- Erector Spinae Plane Block
- Where
- Vietnam
- Volunteers
- 180 people
- Sponsor
- Hanoi Medical University
Oncology, Cancer Pain
Pain ASsessment in CAncer Patients by Machine LEarning (PASCALE)
In cancer patients, the integration between anticancer therapies and palliative care is of fundamental importance. In this context, telemedicine can improve the quality of life (QoL) of chronic patients through self-management…
- Conditions
- Oncology, Cancer Pain, Quality of Life
- Trial name
- PASCALE (NCT04726228)
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- National Cancer Institute, Naples