Clinical trials: Cancer-Associated Pain
Pain
Self-management Support in Cancer Pain
Pain is a prevalent and distressing symptom in patients with cancer, having an enormous impact on functioning and quality of life.
- Trial name
- NCT02333968
- Testing
- Self-management support
- Where
- 2 sites in Netherlands
- Volunteers
- 174 people
- Sponsor
- Maastricht University Medical Center
Gynecologic Cancer, Cancer Related Pain
The Effectiveness of Electroacupuncture and Standard Therapy Compared to Standard Therapy in Gynecological Cancer Pain
Gynecological cancer is cancer that starts in the female reproductive organs. Pain in gynecological cancer can be caused by an underlying malignancy or surgical procedure as well as chronic pain associated with malignancy and…
- Conditions
- Gynecologic Cancer, Cancer Related Pain, Cancer Pain
- Trial name
- NCT06073496
- Testing
- Electroacupuncture
- Where
- 3 sites in Indonesia
- Volunteers
- 58 people
- Sponsor
- Universitas Indonesia
Cancer Pain
The Effect of Patient-Controlled TEAS vs Sham TEAS for Improve Quality of Life in Patients With Cancer Pain
The conduct of a pilot trial is of great significance as a means of assessing the feasibility and harmonization of the research and is a very necessary precursor to the better conduct of formal trials.
- Trial name
- NCT06188286
- Testing
- Transcutaneous electrical acupoint stimulation
- Volunteers
- 94 people
- Sponsor
- Yi Liang
Lung Cancer, Pain
Fentanyl Matrix in Lung Cancer Pain
The purpose of this study is to evaluate the usefulness of fentanyl matrix by assessing patients' satisfaction when administrating fentanyl matrix, a background pain treatment, and a breakthrough pain treatment to lung cancer…
- Trial name
- NCT01060137
- Testing
- fentanyl matrix
- Volunteers
- 268 people
- Sponsor
- Janssen Korea, Ltd., Korea
Opioid-Induced Constipation
Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation
The purpose of this study is to evaluate the safety and efficacy of CB-5945 for the treatment of opioid-induced constipation (OIC) in adults taking opioid therapy for chronic non-cancer pain.
- Trial name
- NCT01901302
- Testing
- CB-5945
- Volunteers
- 61 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Effect of Opioid Infusion Rate on Abuse Liability Potential of Intravenous Hydromorphone for Cancer Pain
In cancer inpatient settings, intravenous (IV) opioids are frequently administered in a bolus fashion in order to obtain immediate pain relief.
- Trial name
- NCT04296305
- Testing
- Hydromorphone, Questionnaire Administration
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- M.D. Anderson Cancer Center
Cancer Pain
An Interventional Study for Patient With Cancer Pain to Evaluate the Efficacy and Safety of OxyNorm® Compared to Morphine Sulfate Through the IV Continuous Infusion.
The purpose of this study is to compare of difference in NRS scores from baseline to the completion of treatment (5 days) in patients with administration of morphine sulfate versus oxycodone hydrochloride.
- Trial name
- SWITCH (NCT02660229)
- Testing
- Oxycodone Hydrochloride, Morphine Sulphate
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Mundipharma Korea Ltd
Opioid-Induced Constipation (OIC)
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation
The purpose of this study is to evaluate the effect and safety of NKTR-118 treatment of opioid-induced constipation in patients with non-cancer-related pain, including those patients that have inadequate response to laxative…
- Trial name
- NCT01323790
- Testing
- NKTR-118
- Where
- 120 sites in United States, Belgium and 6 more
- Volunteers
- 700 people
- Sponsor
- AstraZeneca
Chronic Non-Cancer Pain
Preventive Interventions for Chronic Pain Worsening
This is an open label randomized controlled trial (RCT), which will be conducted with patients of the Copenhagen Wound Healing Center at Bispebjerg Hospital in Copenhagen (DK).
- Trial name
- NCT06351046
- Testing
- Virtual Reality-based Pain Self-management program
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cancer
Therapeutic Patient Education and Cancer Pain
Describe the expectations of therapeutic education for patients in management of cancer pain.
- Trial name
- EFFADOL (NCT02391740)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Centre Francois Baclesse
Oral Cancer, Oral Cavity Cancer
Effectiveness of Opioid vs Pregabalin Plus Naproxen Sodium in Pain Management of Oral Cancer Patients
This randomized clinical study was designed to compare two pain treatment approaches for adults with oral cancer who had moderate to severe pain.
- Conditions
- Oral Cancer, Oral Cavity Cancer, Oral Squamous Cell Carcinoma (OSCC)
- Trial name
- NCT07606638
- Testing
- Tramadol, Pregabalin + Naproxen Sodium
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Mayo Hospital Lahore
Cancer, Chronic Pain
Tapentadol in Chronic Malignant Tumour Related Pain
The purpose of this trial is the characterization of the long term safety profile and long-term dose requirements of tapentadol PR (prolonged release) in patients with malignant tumor-related pain.
- Conditions
- Cancer, Chronic Pain, Pain
- Trial name
- NCT01264887
- Testing
- Tapentadol Prolonged Release
- Where
- 12 sites in Bulgaria, Hungary and 5 more
- Volunteers
- 31 people
- Sponsor
- Grünenthal GmbH
Tumor, Cancer
Oral Bicarbonate as Adjuvant for Pain Reduction in Patients With Tumor Related Pain
The purpose of this study is to: Determine how well people tolerate sodium bicarbonate taken by mouth in higher doses than those usually given for heartburn. Determine if sodium bicarbonate can reduce cancer-related pain.
- Conditions
- Tumor, Cancer, Pain, Malignant Solid Tumor
- Trial name
- NCT01846429
- Testing
- Sodium Bicarbonate
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Cancer Pain, Virtual Reality Immersion
Enhancing Pain Management Among Patients Diagnosed With Stage III and Stage IV of Breast Cancer: The Power of Immersive and Non-Immersive Virtual Reality-Driven Interactive Guided Imagery
Cancer-related pain is one of the most common and distressing symptoms experienced by patients with advanced cancer, particularly among women diagnosed with advanced breast cancer.
- Trial name
- NCT07497451
- Testing
- Immersive Virtual reality guided imagery, VR (VR-Control)
- Where
- Jordan
- Volunteers
- 90 people
- Sponsor
- Middle East University
Cancer Pain, Palliative Care
e-Natureza Blue Care: Nature-based Virtual Reality and Pain Perception
This randomized clinical trial aims to evaluate the effectiveness of immersive nature-based virtual reality in managing chronic pain among oncology patients.
- Trial name
- e-NatBlue (NCT07053228)
- Testing
- Nature-based virtual reality, Standard Pain Management
- Where
- Brazil
- Volunteers
- 130 people
- Sponsor
- Hospital Israelita Albert Einstein
Gynecologycal Cancer, Cancer Related Pain
The Effectiveness of Battlefield Acupuncture (BFA) With Standard Therapy in Gynecological Cancer Pain
Pain is one of the most important symptoms of cancer patients, with nearly 40% of all cancer patients experiencing moderate to severe pain.
- Conditions
- Gynecologycal Cancer, Cancer Related Pain, Cancer Pain
- Trial name
- NCT06115330
- Testing
- Press Needle Acupuncture
- Where
- 3 sites in Indonesia
- Volunteers
- 58 people
- Sponsor
- Universitas Indonesia
Pain Syndrome
Prevention of Taxane-associated Acute Pain Syndrome With Etoricoxib
A phase II randomized clinical trial was conducted to determine whether etoricoxib could prevent or ameliorate the incidence and/or severity of docetaxel-induced acute pain syndrome.
- Trial name
- NCT04565600
- Testing
- Etoricoxib
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Guangdong Provincial People's Hospital
Oncology Pain
Virtual Reality for Port-a-Cath Access
Children with cancer almost universally receive port-a-catheters (ports) to deliver medication, fluids, blood products, and conduct blood tests. Port access requires a needle inserted through the skin to the subcutaneous tissue.
- Trial name
- NCT04931745
- Testing
- Virtual reality, Tables distraction, No or non-technologic distraction
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Interactable Malignant Perineal Pain
Thermal Radiofrequency Versus Neurolytic Saddle Rhizotomyfor Severe Pereneal Cancer Pain
The control of perineal malignant pain is difficult and challenging for pain physicians. Different modalities have been tried to treat this complex pain syndrome including pharmacotherapy and interventional therapy.
- Trial name
- NCT03084575
- Testing
- Thermal radio Frequency, selective (unilateral S3, bilateral S4 and S5) saddle rhizotomy, hyperbaric chemical saddle Rhizotomy (6 % pherol in glycerin), Thermal RF lesioning is done using Bailys RF generator
- Volunteers
- 40 people
- Sponsor
- Cairo University
Cancer Pain, Cancer
Treatment Efficacy of Mindfulness-based Cognitive Therapy for Distress in Advanced Cancer Patients
'Distress' refers to emotional distress, including psychological distress, in cancer patients. This study aims to explore whether mindfulness-based cognitive-behavioral therapy for cancer patients is effective in relieving…
- Conditions
- Cancer Pain, Cancer, Distress, Emotional, Therapy-Associated Cancer
- Trial name
- MBCT (NCT05768256)
- Testing
- Mindfulness-Based Cognitive-behavioral Therapy for Distress
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- CHA University