Clinical trials: Cancer-Associated Pain
Cancer
A Study to Evaluate Efficacy and Safety of Oxycodone/Naloxone Compared to OxyContin in Korean Cancer Patients
Objectives: To prove non-inferiority of Targin compared to Oxycontin in terms of change of pain intensity 1. Primary objective: Change of pain intensity (NRS 0-10) score (average pain over 24 hours obtained each evening) within 4…
- Trial name
- TOP (NCT01313780)
- Testing
- Oxycodone/Naloxone, Oxycodone(single compound)
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Mundipharma Korea Ltd
Cancers, Pain, Lower Back Pain
Open-Label Extension to Evaluate the Long-Term Safety, Tolerability and Analgesic Efficacy
The purpose of this study is to evaluate the long-term safety and tolerability of oxymorphone ER as an analgesic in cancer and lower back pain subjects having chronic moderate to severe pain.
- Trial name
- NCT00904280
- Testing
- Oxymorphone ER
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Nausea With Vomiting Chemotherapy-Induced, Depression, Reactive
Implementation of Personalized Medicine for Optimal Drug Therapy in Cancer
A prospective longitudinal cohort study that will assess the effect of a Personalized Medicine (PM) clinic recommendations on pharmacogenetic variation and/or interacting drugs on plasma drug exposure, effectiveness or toxicity…
- Conditions
- Nausea With Vomiting Chemotherapy-Induced, Depression, Reactive, Cancer Pain
- Trial name
- NCT05830279
- Testing
- Pharmacogenetic testing, Drug-Drug interaction analysis
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chronic Pain
A Comparison of Morphine and Morphine Plus Dexmedetomidine in Chronic Cancer Pain
The purpose of this study is to determine whether dexmedetomidine added to morphine is effective in the treatment of chronic cancer pain.
- Trial name
- NCT02289261
- Testing
- Morphine, Morphine plus dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cukurova University
Chronic Pain, Major Depressive Disorder
The Internet Therapy for Depression Trial
The objective of this trial is to collect data on the feasibility, acceptability, and preliminary effectiveness of internet delivered Cognitive Beaviour Therapy (iCBT) and Acceptance and Commitment Therapy (iACT) interventions…
- Trial name
- INTEREST (NCT04009135)
- Testing
- internet delivered cognitive behavioural therapy (iCBT), online delivered acceptance and commitment therapy (iACT), Attention Control (AC)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Memorial University of Newfoundland
Neoplasm Related Pain (Acute) (Chronic)
Bicarbonate for Tumor Related Pain
The purpose of this study is to: Determine how well people tolerated sodium bicarbonate taken by mouth in higher doses than those usually given for heartburn. Determine if sodium bicarbonate can reduce cancer-related pain.
- Trial name
- NCT01350583
- Testing
- Sodium Bicarbonate (NaHCO3)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Chronic Pain, Insomnia
The Efficacy of CALPXT96™in Improving Sleep Quality in Patients With Chronic Non-cancer Pain
California Poppy has been traditionally used in Herbal Medicine as an analgesic, mild sedative and/or sleep aid. However there are no human clinical trial data to support its use.
- Trial name
- CALPXT96 (NCT02232256)
- Testing
- CALPXT96
- Where
- Canada
- Sponsor
- 9305-9954 Quebec Inc
Cancer, Pain
Nasal Fentanyl for Chronic Cancer Pain
Today, patients with cancer pain in need of opioids for moderate to severe pain get long-acting morphine twice a day and morphine tablets taken on demand in addition.
- Trial name
- NFCP-2 (NCT01906073)
- Testing
- intranasal fentanyl spray, slow release morphine
- Sponsor
- Norwegian University of Science and Technology
Malignant Bowel Obstruction, Cancer Pain
Lidocaine Infusions for Pain in Patients With Malignant Bowel Obstruction
Malignant bowel obstruction is a frequent complication of advanced cancer, particularly of abdominal and pelvic origin, and most affected patients experience pain.
- Conditions
- Malignant Bowel Obstruction, Cancer Pain, Intestinal Obstruction
- Trial name
- NCT07856251
- Testing
- Lidocaine
- Volunteers
- 50 people
- Sponsor
- Fundación Santa Fe de Bogota
Breast Cancer, Colorectal Cancer
Ambulatory Cancer Pain Management: A Feasibility Study
The primary purpose of this study is to examine the feasibility of collecting pain and other symptom data in outpatient treatment centers across multiple institutions in the Texas Medical Center (TMC).
- Conditions
- Breast Cancer, Colorectal Cancer, Lung Cancer, Prostate Cancer
- Trial name
- NCT00507351
- Testing
- Questionnaire
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Cancer-related Pain, Acupressure
Integrating Auricular Point Acupressure Into Real-world Nursing Practice to Manage Cancer-related Pain
The aims of this proposal are to (1) examine the feasibility of providing a training course of Auricular Point Acupressure (APA) for clinical oncology nurses who can integrate APA into real-world nursing care settings and (2)…
- Trial name
- NCT04040140
- Testing
- APA Treatment
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Breast Cancer
Epigenetics and Psychoneurologic Symptoms in Women With Breast Cancer
This study examines the relationship among epigenetic alterations and the development and persistence of psychoneurologic symptoms (cognitive dysfunction, depressive symptoms, anxiety, fatigue, sleep disturbance, and pain) in…
- Trial name
- NCT01411943
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Virginia Commonwealth University
Breast Cancer, Arthralgia
The CEASE Study: Computer Based Educational Module for the Reduction of Arthralgia Syndrome Associated With Endocrine Therapy for Breast Cancer
Patients have been asked to participate in the CEASE study because their treating oncologist has recommended that they start an aromatase inhibitor medication. These medications are associated with joint complaints.
- Trial name
- CEASE (NCT01351844)
- Testing
- Education and exercise intervention, Education and General Exercise
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- George Washington University
OBSERVE PAIN MANAGEMENT PRACTICES IN EMERGENCY DEPARTMENT
An Observational Study of Pain Assessment and Treatment Adequacy of Emergency Cancer Pain
EMERGENCY CANCER PAIN DRAWS CANCER PATIENT TO EMERGENCY DEPARTMENT FOR TREATMENT. HOWEVER, THERE HAS BEEN INCONSISTENCY AND INADEQUACY OF PAIN MANAGEMENT IN EMERGENCY DEPARTMENT.
- Trial name
- NCT01633463
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Tata Memorial Hospital
Chronic Non-Cancer Pain
Test-retest and Experiences During Balance Assessment With the Mini-BESTest
The goal of this observational study is to test psychometric properties of a clinical balance assessment scale, the Mini-BESTest, as well as to explore experiences and beliefs about balance and being balance tested.
- Trial name
- NCT06244602
- Where
- Sweden
- Volunteers
- 73 people
- Sponsor
- Uppsala University
Cancer Patient Confined in the Bed
Osteopathy Treatment for Cancer Pain Related to the Confinement to Bed
Staying confined in the bed is frequent at the end of life. The cancer patients can also experiment this situation, and consequences are painful, with pain increasing with the time.
- Trial name
- OSTEO (NCT03440957)
- Testing
- Osteopathic treatment
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Hospices Civils de Lyon
Cancer Survivors, Cancer Pain
Screening Tool to Identify the Dominant Pain Mechanism in Cancer Survivors: PainsCan
Development and internal validation of an easy-to-use tool for clinical pain assessment. The tool has to be applicable in any clinical practice and without the need for expensive and complicated hospital tools to identify the…
- Trial name
- PainsCan (NCT03981809)
- Testing
- Diagnostic test ("PainsCan") for the identification of the dominant pain mechanisms in cancer survivers with persistent pain
- Where
- Belgium
- Volunteers
- 92 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Pain, Opioid-use Disorder
Validation of the ASI-SR Form in a Population of Chronic Non-cancer Pain Patients
The Swedish version of ASI-SR has shown good feasibility in assessment of addiction patients functioning compare to long and time-consuming ASI, which is upp to date golden standard in Sweden.
- Conditions
- Chronic Pain, Opioid-use Disorder, Quality of Life, Risk Reduction
- Trial name
- ASI-SR (NCT04998734)
- Testing
- ASI-SR
- Where
- Sweden
- Volunteers
- 1 people
- Sponsor
- Uppsala University
Pain
Coaching to Improve Care of Cancer Pain
An estimate of 90% of patients with cancer experience at least moderate pain at some point in their illness, and 42% of patients do not receive adequate palliation.
- Trial name
- NCT00283166
- Testing
- Tailored Education and Coaching
- Where
- 3 sites in United States
- Volunteers
- 258 people
- Sponsor
- University of California, Davis
Chronic Pain
Ultra-low Dose Oral Ketamine for Chronic Pain in the Primary Care Setting
This project is a pilot study to evaluate the analgesic and opioid-sparing effects of ketamine in an ultra-low dose oral formulation as a novel intervention for treatment of chronic non-cancer pain in opioid-tolerant patients in…
- Trial name
- Ketamine (NCT02303847)
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Washington