Clinical trials: Cancer-Related Condition
Tabagism, Lung Cancer
Use of a Smartphone Application on the Detection of Complications Related to Smoking
Smokers do not know the symptoms of cancer and wait on average 5 months with symptoms before consulting. 80% of lung cancers are diagnosed at too late and incurable stage.
- Conditions
- Tabagism, Lung Cancer, Chronic Obstructive Pulmonary Disease
- Trial name
- APPLITABAC (NCT04048954)
- Testing
- Applitabac
- Where
- France
- Volunteers
- 5,671 people, healthy volunteers welcome
- Sponsor
- Weprom
Breast Cancer
The Relationship Between the Differences in Blood Cytokine Values in Breast Cancers.
While classification of malignant breast tumors has traditionally been made according to their histological appearance, nowadays some subtypes have been defined according to their molecular features.
- Trial name
- NCT04540224
- Testing
- Flow-Cytometric analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Lymphedema
Bioelectrical Impedance for Self-monitoring of Lymphedema
Breast cancer treatment-related lymphedema requires life-long self-care is required. No objective measurement mechanism exists that can easily be used to self-monitor arm volume.
- Trial name
- NCT01385488
- Testing
- self-monitor arm volume
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Lymphedema, Breast Cancer
Evaluatıon of sympathetıc Nervous System fındıngs and theır relatıonshıp wıth Symptoms ın patıents wıth Breast Cancer Related Lymphedema
The aim of this study was to evaluate the sympathetic nervous system, small fiber functions and autonomic symptoms in patients with breast cancer related lymphedema and to investigate the relationship between these findings and…
- Trial name
- NCT07019740
- Testing
- CASE GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Marmara University
Hepatocellular Carcinoma, Type 2 Diabetes
Role of LncRNA H19 in The Regulation of IGF-1R Expression
Hepatocellular carcinoma (HCC) is a common cancer that poses a heavy economic burden on the healthcare system. In Egypt, it is the most common cause of mortality and morbidity-related cancer.
- Conditions
- Hepatocellular Carcinoma, Type 2 Diabetes, Cancer
- Trial name
- NCT04767750
- Testing
- Blood sample collection
- Where
- 2 sites in Egypt
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Hepatocellular Carcinoma
Relationship Between Polymorphism of Heat Shock Protein 70 Gene and Hepatocellular Carcinoma
Polymorphisms of HSP70 and tumor necrosis factor-alpha promoter in patients with hepatocellular carcinoma, chronic liver disease and healthy controls will be measured by PCR-RFLP or direct sequencing.
- Trial name
- HSP70 (NCT00769535)
- Testing
- Polymorphisms of HSP70 and TNF promoter
- Where
- 2 sites in Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Pregnancy, Cancer, Cancer in Pregnancy, Gestational Breast Cancer, Pregnancy Related
Maternal Cancer Diagnosis and Treatment During Pregnancy:a Database for Maternal, Fetal, and Neonatal Outcomes
The objective of this study is to follow the treatment options offered to pregnant women diagnosed with cancer and study the impact that their treatment or delay of treatment has on their own health and that of their children.
- Trial name
- CANCRPREGREG (NCT02749474)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Breast Cancer
The Association Between Plasma Metabolites and the Risk, Efficacy and Prognosis in Early Breast Cancer
This study investigates plasma metabolites to clarify the relationship between these metabolites and breast cancer, aiming to identify valuable biomarkers.
- Trial name
- NCT06698679
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Cancer, Disease
Public Survey on Breath Testing for Health and Disease
A brief survey for the public to determine interest in health surveillance and disease detection
- Conditions
- Cancer, Disease, Health Behavior, Health Attitude
- Trial name
- NCT06081452
- Testing
- Survey
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia
Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD
This phase II trial is for patients with acute lymphocytic leukemia, acute myeloid leukemia, myelodysplastic syndrome or chronic myeloid leukemia who have been referred for a peripheral blood stem cell transplantation to treat…
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia, Acute Leukemia of Ambiguous Lineage, Acute Undifferentiated Leukemia
- Trial name
- NCT02220985
- Testing
- Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Fludarabine Phosphate
- Where
- 2 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Pancreatic Cancer, Cholangiocarcinoma
Association Between Cell-free Nucleic Acid in Blood, Urine and Microbiome in Stool With Pancreatobiliary Cancer
Based on the cell free nucleic acid analysis information of blood samples, the results of microbiome and metabolite analysis of stool and urine samples of pancreatic cancer and bile duct cancer patients, the clinical correlations…
- Conditions
- Pancreatic Cancer, Cholangiocarcinoma, Gallbladder Cancer
- Trial name
- NCT05596370
- Testing
- cell free DNA in blood and urine, metabolite/microbiome in urine and stool
- Where
- 2 sites in South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Breast Diseases, Breast Adenocarcinoma
Explore Association Models Between Environmental Hormones andBreast Cancer
investigated the association model between environmental hormone-related living habits and breast cancer, as well as dietary improvement programs through machine learning and clinical validation of patients with breast cancer.
- Trial name
- NCT06765395
- Where
- Taiwan
- Volunteers
- 687 people, healthy volunteers welcome
- Sponsor
- Pei-Hung Liao
Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis), Polymorphism, Single Nucleotide
The Association Between TNFSF4 Polymorphism and CD
The goal of this observational study is to investigate the associations between tumor necrosis factor superfamily member 4 (TNFSF4) gene polymorphisms and the risk of Crohn's disease (CD), and to elucidate the impact of TNFSF4…
- Conditions
- Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis), Polymorphism, Single Nucleotide, Ustekinumab
- Trial name
- NCT07263464
- Testing
- Ustekinumab - Standard Dosage
- Where
- China
- Volunteers
- 818 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Breast Cancer, Cancer-related Problem/Condition
Making Activity Time for Cognitive Health
Approximately 75% of cancer survivors experience some degree of cognitive deficit throughout their cancer experience, with upwards of one third of breast cancer survivors reporting impairments up to a decade after treatment.
- Conditions
- Breast Cancer, Cancer-related Problem/Condition, Cognitive Impairment, Physical Activity
- Trial name
- MATCH (NCT04255225)
- Testing
- Walking for 10 minutes, Walking for 20 minutes, Walking for 30 minutes
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Human Papillomavirus
Natural History, Epidemiology and Pathogenesis of Severe HPV-Related Diseases (Neptune)
Background: Most symptoms of human papillomaviruses (HPV) infection, do not cause serious health problems, but some do. As HPV can cause uncontrolled growth of infected cells, some people can develop benign skin lesions, larger…
- Trial name
- NCT05026138
- Where
- United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Lung Cancer
Genetic Polymorphisms in UGT1A6 and UGT2B7 in Asian Population: Association With Lung Cancer Phenotype
Primary 1. To determine the presence and frequency of novel and known UGT1A6 and UGT2B7 polymorphisms in healthy Chinese, Malay and Indian subjects. 2.
- Trial name
- NCT00717353
- Where
- Singapore
- Volunteers
- healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Breast Cancer Related Lymphedema
Gait Characteristics of Women With Breast Cancer-Related Lymphedema
Upper extremity lymphedema is one of the most common problems associated with cancer treatments in breast cancer survivors. Lymphedema causes asymmetry, changes posture, decreases arm swing due to increased weight, and as a…
- Trial name
- NCT07011277
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Cancer, Breast, Age-related Cognitive Decline
Older Breast Cancer Patients: Risk for Cognitive Decline
The goal of this study is to evaluate the impact of systemic therapy on cognition in older breast cancer patients, explore change in APE, LM and Cognition domains, measure associations between cognitive decline and QOL, and…
- Conditions
- Cancer, Breast, Age-related Cognitive Decline, Cognitive Decline
- Trial name
- TLC (NCT03451383)
- Where
- United States
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Osteoporosis, Hypercalcemia of Malignancy
One Week Comparison Study of PTH and PTHrP Infusions
This is a dose escalation study to determine the maximum tolerable dose of Parathyroid Hormone-related Protein, PTHrP, or Parathyroid Hormone, PTH, that can be given safely over one week in healthy African-American volunteers.
- Conditions
- Osteoporosis, Hypercalcemia of Malignancy, Hyperparathyroidism, Bone Diseases, Endocrine
- Trial name
- NCT01333267
- Testing
- Parathyroid Hormone-related Protein (1-36), parathyroid hormone (1-34), PTH (1-34) and PTHrP (1-36)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Breast Cancer-Related Lymphedema, Autonomic Dysfunction
Evaluation of Sympathetic Skin Response and Its Relationship With Clinical Response to Complex Decongestive Therapy in Patients With Postmastectomy Lymphedema
This prospective observational single-center study aimed to evaluate sympathetic skin response (SSR) in patients with postmastectomy upper extremity lymphedema and to investigate the relationship between SSR parameters and…
- Conditions
- Breast Cancer-Related Lymphedema, Autonomic Dysfunction, Postmastectomy Lymphedema
- Trial name
- BCRL-SSR (NCT07585253)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital