Clinical trials: Cancer-Related Condition
Polycystic Ovary Syndrome
Intestinal Microbiota Survey of Polycystic Ovary Syndrome
Polycystic Ovary Syndrome is kind of disease with unclear etiology. Recent studies on intestinal microbiota have raised the possibility that dysbiosis of intestinal microbiota maybe a novel theory for the development of…
- Trial name
- NCT02937090
- Testing
- Blood Draw, Stool collection
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Cervical Carcinoma, Human Papillomavirus-Related Carcinoma
Prevention and Early Detection of Cervical Cancer Through Self-Administered Screening
This study examines prevention and early detection of cervical cancer through self-administration screening of patients in Western Uganda.
- Trial name
- NCT04927650
- Testing
- HPV testing, Questionnaire Administration
- Where
- Uganda
- Volunteers
- 2,556 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cancer, Cancer-Related Syndrome
Effects of a Multimodal Physical Exercise and Functional Rehabilitation Program on Fatigue, Pain, Functional Capacity and Quality of Life in Cancer Patients With Tumor Asthenia.
Tumor asthenia is the most common symptom associated with cancer and its treatment. Although the estimated prevalence varies between 60-90%, and it is considered the longest-lasting symptom in cancer patients, having the greatest…
- Conditions
- Cancer, Cancer-Related Syndrome, Fatigue
- Trial name
- NCT04761289
- Testing
- Multimodal Exercise and Functional Rehabilitation Program
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Non-Hodgkin's Lymphoma, Acute Leukemia in Remission
Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT
The purpose of this study is to find out if a combination of drugs (these are called: cyclophosphamide, sirolimus, and mycophenolate mofetil) will protect participants better against graft vs.
- Conditions
- Non-Hodgkin's Lymphoma, Acute Leukemia in Remission, Chronic Myeloid Leukemia, Primary Myelofibrosis
- Trial name
- NCT03018223
- Testing
- Fludarabine, Busulfan, Cyclophosphamide
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Pain, Solid Tumor
Pain Control in Hospice Patients With Cancer-Related Pain
RATIONALE: Gathering information over time about cancer-related pain from patients in a hospice and their caregivers may help doctors learn more about pain control.
- Trial name
- NCT00609297
- Testing
- medical chart review, questionnaire administration, survey administration
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Gastric Xanthoma, Helicobacter Pylori Infection
A Study on the Relationship Between Gastric Xanthoma and Gastric Cancer and Precancerous Lesions
To explore the effects of gastric xanthoma on gastric cancer and its precancerous lesions, so as to better prevent the occurrence and development of gastric cancer.
- Conditions
- Gastric Xanthoma, Helicobacter Pylori Infection, Gastric Cancer, Intestinal Metaplasia
- Trial name
- NCT06282484
- Where
- China
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Chronic Myeloproliferative Disorders, Leukemia
Measuring Changes in Blood in Patients at High Risk of Cytomegalovirus Infection After Undergoing Donor Bone Marrow Transplant or Peripheral Blood Stem Cell Transplant
RATIONALE: Tests that measure certain changes in blood in patients at high risk of cytomegalovirus infection may help doctors learn more about predicting cytomegalovirus infection after donor stem cell transplant.
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00716911
- Testing
- ganciclovir, polymerase chain reaction, flow cytometry
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
SSTR-related Disease, Tumor
Somatostatin Receptor PET/CT in SSTR-Related Disease Patients
To evaluate the potential usefulness of 68Ga/18F-TATE/JR11/LM3 positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various SSTR-related disease patients.
- Conditions
- SSTR-related Disease, Tumor, Positron Emission Tomography, Metastasis
- Trial name
- NCT06690957
- Testing
- 68Ga/18F-TATE/JR11/LM3
- Where
- 3 sites in China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University
Dehydration, Advanced Cancers
Physician Perceptions About Parenteral Hydration in Latin America and Spain
The purpose of this study is to assess palliative care physicians' attitudes, beliefs and practice patterns related to parenteral hydration at the end of life in Latin America and Spain. Objectives: 1.
- Trial name
- NCT01011140
- Testing
- Survey
- Where
- United States
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Pleuropulmonary Blastoma, Cystic Nephroma
DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study
Background: Pleuropulmonary blastoma (PPB) is a rare fast-growing lung tumor that is associated with other, rare tumor types. Most cases of PPB appear in children younger than 6 years of age.
- Conditions
- Pleuropulmonary Blastoma, Cystic Nephroma, Ovarian Sertoli-Leydig Cell Tumors, Ocular Medulloepithelioma
- Trial name
- NCT01247597
- Where
- 2 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Endocrine Disease, Infertility
Evaluation of Women With Endocrine and Reproductive-Related Conditions
This study was designed to allow inpatient and outpatient evaluation of women with a variety of reproductive and endocrine-related disorders for purposes of research and physician education.
- Conditions
- Endocrine Disease, Infertility, Leiomyoma, Endometriosis
- Trial name
- NCT00001850
- Where
- United States
- Volunteers
- 833 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Stomach Neoplasms
Association Between Mitochondrial DNA Content and Risk of Gastric Cancer
Compelling epidemiological evidence indicates that alterations of mitochondrial DNA, including mutations and abnormal content of mitochondrial DNA (mtDNA), are associated with the initiation and development of gastric cancer.The…
- Trial name
- NCT02944539
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
T-Cell Dysfunction, Chemotherapy Effect
Studying the Senescent T Cell Features and Its Relationship with the Chemotherapy Efficacy in Young TNBC
The goal of this observational study is to learn about the features of senescent T lymphocytes induced by chemotherapy and its relationship with the efficacy of neoadjuvant chemotherapy in young triple-negative breast cancer…
- Conditions
- T-Cell Dysfunction, Chemotherapy Effect, Adverse Events
- Trial name
- STFREiYTNBC (NCT06684054)
- Testing
- docetaxel, anthracycline, cyclophosphamide
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Breast Cancer
Study of Blood Samples From High-Risk Postmenopausal Women Who Received Treatment on Breast Cancer Prevention Clinical Trials NSABP-P-1 or NSABP-P-2
RATIONALE: Studying the genes expressed in samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00967239
- Testing
- DNA analysis, polymorphism analysis, laboratory biomarker analysis
- Volunteers
- 1,881 people, healthy volunteers welcome
- Sponsor
- NSABP Foundation Inc
Colorectal Neoplasia, Colorectal Inflammation
Association Between Confocal Laser Endomicroscopic (CLE) Features and Colorectal Mucosal Microbiome
The purpose of this study is to determine whether an association between endomicroscopic pattern and colorectal mucosal microbiome exists.
- Conditions
- Colorectal Neoplasia, Colorectal Inflammation, Hyperplasia, Mucosal Microbiome
- Trial name
- NCT02063919
- Testing
- the mucosal microbiome in the biopsy specimen was analysed
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shandong University
Lymphedema, Secondary
Skin Biophysical Measures for Assessing Head and Neck Cancer-Related External Lymphedema
Selected measurements in healthy persons of skin tissue dielectric constant as reference values for subsequent use to evaluate patients with head and neck lymphedema.
- Trial name
- NCT04457375
- Testing
- TDC
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Cannabis Use Disorder, Mild, Cannabis Use Disorder, Moderate
Pilot Test of Parent-Focused Cannabis-Related Actions and Practices Intervention for Adolescent Marijuana Abuse
The randomized clinical trial involves the pilot-testing of a theory-guided, empirically based, and low-cost intervention designed for legal medical marijuana-using parents to enhance parenting behaviors that limit youth exposure…
- Trial name
- CAP (NCT04923230)
- Testing
- Cannabis Actions and Practices Resource for Parents
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Cancer, Healthcare Professionnals
Assessment of Cancer-related Post-traumatic Stress in Patients and Caregivers in the Year Following Diagnosis, and Identification of Their Expectations of Personalized Support - CANDYSTRESS
The impact of cancer on the lives of patients and their caregivers is undeniable. In addition to the potentially traumatic aspects (i.e., creating a very violent emotional shock) linked to the announcement of the disease and the…
- Conditions
- Cancer, Healthcare Professionnals, Caregiver Distress, Caregiver
- Trial name
- CANDYSTRESS (NCT06944262)
- Where
- 2 sites in France
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Lille University
Adult ALL
Virtual Reality-Infused Treadmill Training on Aging-Related Outcomes
Age-associated motor and cognitive deficits increase the risk of falls, a major cause of morbidity and mortality. Emerging evidence suggests that inflammatory mediators lead to impaired functional capacity and frailty in the…
- Trial name
- V-TARGET (NCT06727942)
- Testing
- V-TARGET intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Survivorship, Recurrent
Association Between Exercise, Patient-Reported Outcomes, and Clinical Events in Adult Cancer Survivors
This protocol is a retrospective study using observational data to conduct a target trial emulation to examine the association of exercise on cancer specific endpoints and other clinical outcomes in cancer survivors.
- Conditions
- Survivorship, Recurrent, Recurrence, Cancer
- Trial name
- NCT07030686
- Testing
- Exercise
- Where
- 3 sites in United States
- Volunteers
- 70,000 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center