Clinical trials: Cancer-Related Condition
Non Hodgkin Lymphoma, DLBCL
Cardiotoxicity and Other Late Effects After Radiotherapy and Immuno-chemoTherapy in Non-Hodgkin lYmphoma
Survivors of non-Hodgkin lymphoma and a control group will be screened for (sub)clinical cardiovascular disease, to assess the influence of contemporary treatments on risk and burden of (sub)clinical cardiovascular disease and…
- Conditions
- Non Hodgkin Lymphoma, DLBCL, Cardiovascular Diseases, Cardiomyopathies
- Trial name
- CLARITY (NCT07041827)
- Testing
- Cardiovascular assessment
- Where
- Netherlands
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- The Netherlands Cancer Institute
Insomnia, Related Distress Among Cancer Caregivers
Study of Cognitive Behavioral Therapy for Insomnia (CBT-I) and Acupuncture for Insomnia and Related Distress Among Cancer Caregivers
The other aim of this study is to determine which of those two treatments (acupuncture or cognitive behavioral therapy) works better for treating insomnia in Informal Caregivers of cancer patients.
- Trial name
- NCT03012425
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Acupuncture, questionnaires
- Where
- 3 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Exostoses, Multiple Hereditary
Height, Ulnar Length and Forearm Function in Multiple Hereditary Exostoses
the purpose of the present registry is to describe the epidemiology of forearm deformities in patients with Hereditary Multiple Exostoses and to identify, independent predictors of severity of the disease and potential…
- Trial name
- NCT05914298
- Testing
- blood and buccal swab genetic test, PUL, Range of motion
- Where
- Italy
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Colorectal Neoplasms, Nonalcoholic Fatty Liver Disease
Study of the Association of Nonalcoholic Fatty Liver Disease With Colorectal Malignant Neoplasm
The aim of this sudy is to investigate the prevalence of colorectal cancer (CRC) in patients with nonalcoholic fatty liver disease (NAFLD) and evaluate whether NAFLD is a risk factor for CRC.
- Trial name
- NWC (NCT01657773)
- Testing
- Ultrasound examination and Colonoscopy examination
- Where
- China
- Volunteers
- 2,315 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Human Papillomavirus Infection
Throat and Other HPV-Related Cancers in Men: Identifying Them Early
This trial studies the screening of human papillomavirus (HPV)-related oropharyngeal and anogenital cancers. Learning the relationship between HPV and cancer risk in men who test positive for HPV antibodies or circulating HPV DNA…
- Trial name
- TRINITY (NCT02897427)
- Testing
- Biomarker Analysis, Biospecimen Collection, Ultrasonography
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Cancer of Breast, Cardiorespiratory Fitness
Change in Cardiorespiratory Fitness and Breast Cancer Incidence and Mortality
The aim of this observational study is to investigate the association between mid-life changes in cardiorespiratory fitness and the risk of breast cancer incidence and mortality among Swedish women.
- Conditions
- Cancer of Breast, Cardiorespiratory Fitness, Occupational Health
- Trial name
- NCT05729451
- Volunteers
- 53,644 people, healthy volunteers welcome
- Sponsor
- The Swedish School of Sport and Health Sciences
Seborrheic Keratosis (SK), Oxidative Stress
Relationship Between Serum Xanthine Oxidase Levels and Seborrheic Keratosis
This observational study aims to examine the relationship between serum xanthine oxidase (XO) levels and seborrheic keratosis (SK), a common benign skin tumor, especially in middle-aged and older adults.
- Conditions
- Seborrheic Keratosis (SK), Oxidative Stress, Skin Aging
- Trial name
- SK-XO (NCT07095348)
- Testing
- Serum Xanthine Oxidase Level Assessment
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sri Nauli Dewi Lubis
Breast Neoplasm
CanRestoreFunction Cancer-related Fatigue ( CRF )
The goal of this randomized control trial is to determine if participating in an 8-week online cancer-related fatigue management intervention consisting of individualized exercise program, one-on-one goal setting and action plan…
- Trial name
- CRF (NCT05868187)
- Testing
- Exercise, Problem-Solving Session and Education
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Chronic Musculoskeletal Pain, Posttraumatic Stress Disorder (PTSD)
Neurobiological and Psychological Benefits of Exercise in Chronic Pain and PTSD
The wars in Iraq and Afghanistan are creating a new generation of Veterans, including an increasing number of women Veterans, who present with comorbid PTSD and chronic pain conditions from recent deployment-related physical…
- Conditions
- Chronic Musculoskeletal Pain, Posttraumatic Stress Disorder (PTSD), Mild or Moderate Traumatic Brain Injury
- Trial name
- EXCPPTSD (NCT03283163)
- Testing
- Exercise Testing and Training
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Sexual Dysfunction
Female Sexual Dysfunction Intervention
The goal of this psychosocial research study is to learn whether a website program called "Tendrils: Sexual Renewal for Women after Cancer " may help female cancer survivors improve their sex lives when used either as a self-help…
- Trial name
- NCT00614276
- Testing
- Focus Group, TENDRILS, Questionnaires
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
MULTIPLE MYELOMA
UARK 2005-05, Coagulation-Related Effects of Velcade Treatment in Patients With Relapsed or Refractory Multiple Myeloma
To evaluate changes in coagulation (blood clotting) factors and platelet function in multiple myeloma participants undergoing VELCADE treatment for the first time.
- Trial name
- NCT00569868
- Testing
- Velcade
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Healthy
Primary Prevention Trial of the Health Effects of Antioxidant Vitamins and Minerals.
It has been suggested that a low dietary intake of antioxidant vitamins and minerals increases the incidence rate of cardiovascular disease and cancer.
- Trial name
- NCT00272428
- Testing
- ascorbic acid, vitamin E, beta carotene, selenium, zinc
- Where
- France
- Volunteers
- 13,000 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Lung Cancer, Squamous Lung Dysplasia
Deuterated Phenanthrene Tetraol in Smokers Who Are at High Risk For Lung Cancer
This clinical trial studies deuterated phenanthrene tetraol in smokers who are at high risk for lung cancer. Studying samples of urine in the laboratory from smokers who are at high risk for lung cancer may help doctors learn…
- Conditions
- Lung Cancer, Squamous Lung Dysplasia, Tobacco Use Disorder
- Trial name
- NCT01673711
- Testing
- deuterated phenanthrene tetraol, pharmacological study, laboratory biomarker analysis
- Where
- 3 sites in United States, Canada
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Colorectal Carcinoma, Obesity-Related Malignant Neoplasm
A Dietary Intervention (Soy Soft Pretzels) for Reducing Chronic Inflammation in Obese Individuals
This clinical trial compares the effects of soy soft pretzels versus wheat pretzels on inflammatory markers in individuals with obesity.
- Trial name
- NCT07650409
- Testing
- Biospecimen Collection, Dietary Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Trauma, Psychological, Sexual Violence
CFT Self-Help for Accessing Cervical Screening After Sexual Assault
The aim of this study is to evaluate the feasibility of a new self-help intervention designed to support individuals (anyone with a cervix) to access cervical cancer screening following the experience of sexual assault, by…
- Conditions
- Trauma, Psychological, Sexual Violence, Cervical Cancer
- Trial name
- NCT04104724
- Testing
- Self-help
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Royal Holloway University
Breast Cancer, Lymphedema
Effect of Upper Limb Posture on Limb Volume as Expressed in Circumference Measurement in Healthy Women and in Women With Breast Cancer Related Lymphedema
Lymphedema is one side effect of breast cancer treatment. Measuring the edematous limb enables monitoring changes in the lymphedema and the effect of treatment.
- Trial name
- NCT01672125
- Testing
- circumferential measurements in different upper limb positions.
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Intracranial Neoplasm, Hyperlactatemia
The Relationship of Anesthesia Method With Serum Lactate Level in Craniotomies
The investigators aimed to research the incidence of hyperlactatemia in craniotomy cases, the relationship of lactate elevation with tumor type and other factors that may be related, and whether the general anesthesia method…
- Conditions
- Intracranial Neoplasm, Hyperlactatemia, Brain Tumor, Hypoperfusion
- Trial name
- NCT05145049
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ankara Diskapi Training and Research Hospital
Colorectal Cancer, Colorectal Cancer Metastatic
Possible Association of Intestinal Helminths and Protozoa With Colorectal Cancer Pathogenesis
Colorectal cancer (CRC) has the third highest cancer incidence in the world. There is mounting evidence that the intestinal microbiota plays an important role in colorectal carcinogenesis.
- Conditions
- Colorectal Cancer, Colorectal Cancer Metastatic, Intestinal Parasite, Protozoan Infections
- Trial name
- NCT03173001
- Testing
- Parasitological examination
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan
Liver Cancer
Effects of Antiviral Therapy on HBV Reactivation
Hepatitis B virus (HBV) reactivation happens after liver resection for HBV-related hepatocellular carcinoma (HCC) patients, particularly for those with positive serum HBV-DNA .
- Trial name
- HBV-DNA(-) (NCT02829359)
- Testing
- Entecavir therapy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Polycystic Ovary Syndrome (PCOS)
Amelioration of Polycystic Ovary Syndrome Related Disorders by Supplementation of Thymoquinone and Metformin
Objective: To investigate the potential benefit of adding Thymoquinone to Metformin in alleviating symptoms of polycystic ovarian syndrome. Methods: 207 overweight and obese PCOS Patients were divided into two groups.
- Trial name
- NCT04852510
- Testing
- Metformin Versus a combination of Metformin and Thymoquinone (TQ)
- Where
- Saudi Arabia
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Saudi German Hospital - Madinah