Clinical trials: Candida
Endodontic Treatment
Disinfection Effect of Gaseous Ozone
The current study aimed to investigate the effect of gaseous ozone in disinfection the root canals of primary teeth. Thirty-six primary molars of 36 completely healthy patients (aged 5-10) were included in the study.The included…
- Trial name
- NCT06470126
- Testing
- 2.5% NaOCl group: The interventions performed in the study are root- canal therapies and disinfection procedure of these therapies., 0.9% sterile saline solution combined with 80 seconds: The OzonyTronX® interventions performed in the study are root- canal therapies and disinfection procedure of these therapies., 2.5% NaOCl with 80 seconds OzonyTronX®:The interventions performed in the study are root- canal therapies and disinfection procedure of these therapies.
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ankara University
Edentulous Alveolar Ridge In Mandible, Edentulous Jaw
A Study Comparing Two Different Denture Base Materials in Implant Retained Overdentures
The aim of removable prosthodontics is not only to restore lost oral structures but also to preserve the remaining tissues. Implant-retained overdentures have shown superior outcomes over conventional dentures by reducing…
- Conditions
- Edentulous Alveolar Ridge In Mandible, Edentulous Jaw, Edentulous Mouth, Implant Supported Overdenture
- Trial name
- NCT07271641
- Testing
- Conventional acrylic resin denture, Flexible resin denture
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Candidiasis
Effect of Probiotic Bacteria on Oral Candida in Frail Elderly
The aim of this study is to investigate the effect of daily intake of the probiotic Lactobacillus Reuteri on the prevalence and counts of oral Candida in frail elderly living in nursery homes.
- Trial name
- NCT02391532
- Testing
- L. reuteri DSM 17938/ATCC PTA
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Gout
A Study to Determine the Safety, Tolerability, PK and Preliminary PD of SSS11 in Chinese Healthy Adult Volunteers
To evaluate the safety, tolerability, PK and preliminary PD of SSS11 for injection in chinese healthy adult volunteers.
- Trial name
- NCT04047394
- Testing
- PEGylated recombinant candida urate oxidase
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Shenyang Sunshine Pharmaceutical Co., LTD.
Microbiota, Constipation
A Probiotic Blend Reduces Gastrointestinal Symptoms and Positively Impacts Microbiota Modulation in a Randomized Study
This randomized, placebo-controlled, double-blind study will determine the effect of daily supplementation with a probiotic blend in 60 apparently healthy men and women recruited at a single investigational center in Northeast…
- Conditions
- Microbiota, Constipation, Candida
- Trial name
- NCT05614726
- Testing
- 575mg [30 billion colony forming units] probiotic blend of Bifidobacterium breve, Lactobacillus acidophilus, Lacticaseibacillus rhamnosus, Saccharomyces boulardii, and alpha amylase
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Oral Lichen Planus
Efficacy of Topical Treatment With Clobetasol in Symptomatic Oral Lichen Planus.
The investigators want to study the effect of clobetasol in symptomatic oral lichen planus. The investigators will include 90 patients and randomly allocate them in three groups.
- Trial name
- NCT04364555
- Testing
- Clobetasol Propionate
- Where
- 2 sites in Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Malmö University
Diabetes Mellitus, Polyneuropathies
Neurogenic Inflammation in Diabetes
Polyneuropathy is a complication of diabetes mellitus which leads to decreased sensation in arms and legs. This in turn can lead to the development of (infected) foot ulcers.
- Conditions
- Diabetes Mellitus, Polyneuropathies, Arthropathy, Neurogenic
- Trial name
- NCT01370837
- Testing
- Intracutaneous injection of Candida albicans antigen., Temperature measurement.
- Where
- Netherlands
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Candidosis Vaginal
Safety and Tolerability Studies of CanProFem-AK, Vaginal Suppositories in Healthy Volunteers
The study object of this clinical trial is CanProFem-AK, 100 mg suppositories. The Pharmacological group - Antifungal drug for external use.
- Trial name
- NCT06535126
- Testing
- CanProFem-AK
- Where
- Kazakhstan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Industrial Microbiology LLP
Candidemia
Bio-assay Development and Implementation for Fungal Infection Detection
The purpose of this study is to determine whether the newly developed biosensor can be used to detect and quantify fungal cells in human blood samples.
- Trial name
- NCT02333266
- Testing
- Candidemia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Candida Infection, Oral Thrush
Oropharyngeal Candidiasis (OPC) and S-ECC
The overall objective of this study is to investigate the association of early Candida infection (known as oral thrush or oropharyngeal candidiasis, OPC) in children during the first year of life with the onset and severity of…
- Conditions
- Candida Infection, Oral Thrush, Early Childhood Caries
- Trial name
- Oral-Thrush (NCT05761197)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Temple University
Breast Infection
Painful Breastfeeding and Bacterial or Yeast Infection
The aim of this study is to investigate the prevalence of yeast and bacteria in women with breastfeeding pain and to identify signs and symptoms.
- Trial name
- NCT01631461
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Candidiasis
Immunological Interaction Between the Host and Candida Albicans Biofilm
Candida albicans is one of the most common nosocomial infection and the onset relies on the host immune status. The purpose of this study is to determine the immunological profile of patients infected with Candida albicans, that…
- Trial name
- NCT01919931
- Where
- Belgium
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Candida Infection, Denture Stomatitis
The Anti-microbial Effect of Titanium Dioxide Nano Particles in Complete Dentures Made for Edentulous Patients
Although cleaning dentures by immersion in chemical denture cleaning solutions is effective in reducing the number of bacteria, a large number remains adhering to the denture surface.
- Trial name
- NCT03666195
- Testing
- Titanium Dioxide Nanoparticles
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fungal Infections, Primary Immune Deficiencies
Studies of Disorders With Increased Susceptibility to Fungal Infections
Background: Researchers are interested in studying disorders that make individuals more susceptible to fungal infections, specifically infections with the Candida yeast.
- Trial name
- NCT01222741
- Where
- United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Candida Albicans Infection, Cigarette Smoking
Curcumin; Rose Bengal; Denture Stomatitis
Cigarette smoking in conjugation with bad oral hygiene is considered a typical predisposing factor for many oral diseases including denture stomatitis.
- Trial name
- NCT04837664
- Testing
- Curcumin, Rose Bengal, Nystatin
- Where
- Saudi Arabia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- King Saud University
HIV/AIDS, Periodontal Diseases
Effects of Periodontal Treatment on HIV-infected Patients
Periodontal diseases, such as chronic periodontitis (CP), frequently occur in immunosuppressed patients, including HIV-infected patients.
- Trial name
- NCT03262402
- Testing
- Basic periodontal treatment
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Autosomal-dominant Hyper-IgE Syndrome
Safety, Tolerability, and Immunogenicity of One Dose of NDV 3A Vaccine in People With STAT3-Mutated Hyper-IgE Syndrome
Background: AD-HIES is a disease that weakens the immune system. It puts people at risk for infections, particularly Staph and Candida infections.
- Trial name
- NCT02996448
- Testing
- NDV-3A
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Obesity & Overweight, Orthodontic Treatment
Impact of Increased Body Mass Index on Adolescent Fixed Orthodontic Treatment. A Prospective Longitudinal Study
The goal of this prospective observational study is to assess the influence of increased body mass index (BMI) on various oral health and orthodontic-related parameters in adolescents undergoing orthodontic therapy (OT) with…
- Trial name
- NCT07217756
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Printed Dentures
Effect of Printing Layer Thickness on Growth of Candida Albicans in Completely Edentulous Patients Rehabilitated With 3D-Printed Maxillary Complete Denture Bases.
In completely edentulous patients rehabilitated with 3D-printed maxillary dentures bases, does the printing layer thickness affect candidal adherence and growth on the fitting surface of dentures.
- Trial name
- NCT07303530
- Testing
- printing layer thickness of denture
- Where
- 2 sites in Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vulvovaginitis, Candidal, Vulvovaginal Candidiasis
Safety of Pregnant Subjects Exposed to Ibrexafungerp Including Infant Outcomes
This is an ongoing evaluation of subjects exposed to ibrexafungerp while pregnant. The study population will include pregnant women of any age.
- Conditions
- Vulvovaginitis, Candidal, Vulvovaginal Candidiasis, Candida Infection, Vaginal Candidiasis
- Trial name
- NCT05908682
- Testing
- Non-interventional study
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline