Clinical trials: Candidiasis of Vagina
Vulvovaginal Candidiasis (VVC)
Evaluation of the Efficacy of a Probiotic Product as an Adjuvant Treatment for Vulvovaginal Candidiasis
Open-label, randomized clinical trial with a control group and a 4-week intervention period. The study will evaluate the efficacy of the probiotic supplement Bioithas WOMAN® as an adjunctive treatment in women with clinically…
- Trial name
- NCT07603895
- Testing
- Bioithas WOMAN®
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Bioithas SL
Candida Vulvovaginitis
Efficacy and Safety of Oral Ibrexafungerp (SCY-078) vs. Placebo in Subjects With Acute Vulvovaginal Candidiasis (VANISH 303)
This is a Phase 3, randomized, multicenter, double-blind, placebo-controlled study to evaluate the efficacy and safety of oral Ibrexafungerp (SCY-078) compared to placebo in female subjects 12 years and older with AVVC.
- Trial name
- NCT03734991
- Testing
- Ibrexafungerp
- Where
- 25 sites in United States
- Volunteers
- 376 people
- Sponsor
- Scynexis, Inc.
Health, Vulvovaginal Candidiasis
Effect of Exercise on Spread of the Miconozole Nitrate OVULE in the Vagina
This study uses MRI to detect the spread of the Miconozole Nitrate OVULE within the vagina. The effect of moderate amounts of physical activity on the spread will be evaluated, and compared to no physical activity.
- Trial name
- NCT00194324
- Testing
- Miconazole nitrate, Magnetic resonance imaging, Moderate levels of exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Candidiasis, Vulvovaginal
Study of the Vaginal Microbiota and the Potential of a Vaginal Probiotic Cream in Vaginal Candidosis
This study evaluated the effect of a vaginal gel containing three live probiotic bacteria on vaginal Candida albicans infection in flemish patients (n=20).
- Trial name
- NCT03975569
- Testing
- Probiotic vaginal gel
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
Recurrent Vulvovaginal Candidiasis
Effect of a Lactobacillus Strain on the Prevention of Recurrent Vaginal Candidiasis
The objective of this study is to evaluate the efficacy of the consumption of the one probiotic strain in the prevention of new vaginal candidiasis events in women with recurrent vaginal candidiasis.
- Trial name
- NCT04639544
- Testing
- Lactobacillus strain
- Where
- Spain
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Biosearch S.A.
Vaginal Candidiasis
Prevention of Recurrent Vulvovaginal Candidiasis With Lactibiane Candisis 5M®
Vulvovaginal candidiasis (VVC) is a common infection among women that is associated with considerable morbidity and health-care cost. 75% of women will suffer of Candida infection for at least one time in their life.
- Trial name
- NCT00915629
- Testing
- Lactibiane candisis 5M
- Where
- France
- Volunteers
- 134 people
- Sponsor
- PiLeJe
Bacterial Vaginosis, Vulvovaginal Candidiasis
Exploring the Effects of an Intravaginal Lactic Acid Gel on the Vaginal Microbiome
This project aims to investigate if the contraceptive method, Phexxi, causes changes to the composition of the vaginal microbiome.
- Trial name
- NCT05753813
- Testing
- Phexxi
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Queen's Medical Center
Vulvovaginal Candidiasis
Monthly Itraconazole Versus Classic Homeopathy for Treatment of Recurrent Vulvovaginal Candidiasis (RVVC)
A prospective study to evaluate the efficacy of classic homeopathic therapy compared to maintenance itraconazole therapy with and without additional exogenous lactobacillus for treatment of recurrent Candida vaginitis.
- Trial name
- NCT00895453
- Testing
- itraconazole, lactobacillus gasseri, classic homeopathy (carcinosin M, nux vomica, pulsatilla M, ferrum metallicum, sepia M, etc. as prescribed)
- Where
- Austria
- Volunteers
- 144 people
- Sponsor
- Medical University of Vienna
Candidiasis, Vulvovaginal
Effect of Saccharomyces Cerevisiae on Vulvo-vaginal Candidiasis
This study aims to evaluate the effect of a specific strain of Saccharomyces cerevisiae on improving the effectiveness of conventional treatment of vulvo-vaginal candidiasis.
- Trial name
- NCT02859493
- Testing
- Saccharomyces cerevisiae
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Lesaffre International
Vulvovaginal Candidiasis
Safety and Equivalence of a Terconazole Vaginal Suppository (Test Product) Compared to the Reference Terconazole Vaginal Suppository in the Treatment of Vulvovaginal Candidiasis
The objectives of this study were to demonstrate comparable safety and efficacy of Terconazole Vaginal Suppositories, 80 mg(Test Product) and Terconazole Vaginal Suppositories, 80 mg(Reference Product) in the treatment of…
- Trial name
- NCT00803738
- Testing
- Terconazole Vaginal Suppository, Terazol Vaginal Suppository
- Volunteers
- 572 people
- Sponsor
- Padagis LLC
Vulvovaginal Candidiasis
Comparative Performance of a Vaginal Yeast Test
The purpose of this study is to establish lay user performance criteria for the SavvyCheck Vaginal Yeast Test in comparison to standard vaginal yeast culture and identification method for Candida (the Reference Method).
- Trial name
- NCT05079711
- Testing
- SavvyCheck Vaginal Yeast Test (rapid, point-of-care diagnostic test)
- Where
- 3 sites in United States, Germany
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Clotrimazole, Ovulen
Comparative Efficacy of Ovule vs Tablet
The study is focused to prove that the efficacy of a new Canesten formulation (ovule) is not inferior to the old Canesten formulation (tablet)
- Conditions
- Clotrimazole, Ovulen, Vulvovaginal Candidiasis
- Trial name
- NCT00755053
- Testing
- Clotrimazole, vaginal ovule, Clotrimazole, vaginal tablet
- Where
- 17 sites in Germany, Russia
- Volunteers
- 466 people
- Sponsor
- Bayer
Candidiasis, Bacterial Vaginosis
Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin and Ketoconazole for the Treatment of Mixed-Type Vaginosis, Bacterial Vaginosis and Candidiasis
The purpose of this study is to determine the Efficacy, Tolerability \& Safety of Combination of Clindamycin 100mg and Ketoconazole 400mg in Vaginal Capsules, used for 7 consecutive days in patients with Mixed-Type Vaginosis…
- Trial name
- NCT00889356
- Testing
- Clindamycin 100mg and Ketoconazole 400mg, Tetracycline 100mg and Amphotericin B 50mg
- Where
- Brazil
- Volunteers
- 160 people
- Sponsor
- Zodiac Produtos Farmaceuticos S.A.
Vulvovaginal Candidiasis
Multi-Gyn FloraFem Study for Treatment of Vulvo Vaginal Candidiasis Symptoms
Women diagnosed with Vulvovaginal Candidiasis by the health care professional will be enrolled in the study. All participants should fulfil inclusion and exclusion criteria. The study product will be used for 5 days, once a day.
- Trial name
- NCT05552378
- Testing
- Multi-Gyn FloraFem
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karo Pharma AB
Vaginitis
A Study of the Efficacy and Safety of WXSH0102 in Treating VCC Patients
This study is a multicenter, randomized, double-blind, active-controlled, dose-ranging clinical trial designed to evaluate the efficacy and safety of the investigational drug compared to the active comparator in the treatment of…
- Trial name
- NCT06771063
- Where
- 2 sites in China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Cisen Pharmaceutical CO., LTD.
Recurrent Vulvovaginal Candidiasis
Study of Lactobacillus in Adjuvant Treatment of RVVC
We are trying to determine if Clotrimazole vaginal tablets with oral Lactobacillus is better than Clotrimazole vaginal tablets in Preventing the Recurrence of vulvovaginalcandidiasis
- Trial name
- NCT04699240
- Testing
- clotrimazole vaginal tablets, Clotrimazole vaginal tablets+ Lactobacillus
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Peking University Shenzhen Hospital
Vulvovaginal Candidiasis
MGCD290 and Fluconazole Versus Fluconazole Alone for the Treatment of Moderate to Severe Vulvovaginal Candidiasis
The primary objective of the study is to evaluate the rate of therapeutic cure of the combination treatment of MGCD290 and fluconazole as compared to that of fluconazole alone at Test of Cure Visit for patients with moderate to…
- Trial name
- NCT01497223
- Testing
- MGCD290
- Where
- 19 sites in United States
- Volunteers
- 220 people
- Sponsor
- MethylGene Inc.
Vaginal Candidiasis
Use of Oral Probiotics as an Adjunctive Therapy to Fluconazole in the Treatment of Yeast Vaginitis
Yeast vaginitis is a very common ailment affecting premenopausal women in Nigeria. This condition is more prevalent in the age group between 21-30 years.
- Trial name
- NCT00479947
- Testing
- Probiotics (Natural product), Probiotics (L. rhamnosus GR-1 and L. reuteri RC-14)
- Where
- Nigeria
- Volunteers
- 100 people
- Sponsor
- Faith Mediplex
Primary Sjögren Syndrome, Vaginitis Candida
Sjögren and Gynecologic Considerations
Sjögren's syndrome is an autoimmune disorder characterized by glandular and extra-glandular manifestations. It is called primary Sjögren's syndrome (pSS) in absence of another connective tissue disease.
- Conditions
- Primary Sjögren Syndrome, Vaginitis Candida, Vaginitis, Sexual Dysfunction
- Trial name
- NCT05670535
- Testing
- Visual analogue scale (VAS) for dyspareunia, Visual analogue scale (VAS) for vaginal dryness, The European League Against Rheumatism Sjögren's Syndrome Disease Activity Index (ESSDAI)
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people
- Sponsor
- Ankara City Hospital Bilkent
Bacterial Infections, Treatment of Fungal Infections, Candidiasis
Prospective Clinical Study, Using a Medical Device (RepHegyn) as an Adjuvant in the Treatment of Fungal (Candidiasis) and Bacterial Infections
The medical device It is indicated to promote the re-epithelialization processes of the vaginal mucosa, in the prevention of vaginal conditions of bacterial and fungal origin, and as an adjuvant in their treatment.
- Trial name
- NCT07367295
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Innate srl