Clinical trials: Cannabis Dependence
Cannabis Dependence
Study of Long-Acting Injectable Naltrexone to Treat Cannabis Dependence
This is an 8 week, outpatient research study testing the use of long-acting naltrexone (Vivitrol) as a treatment for marijuana dependence.
- Trial name
- NCT02088177
- Testing
- Long-acting injectable naltrexone
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- New York State Psychiatric Institute
Marijuana Dependence
Effect of Baclofen on Marijuana Withdrawal and Relapse
The purpose of this study is to determine if baclofen dose-dependently decreases marijuana's direct effects and symptoms of marijuana withdrawal and thus decreases marijuana relapse.
- Trial name
- NCT00373295
- Testing
- Baclofen, Marijuana
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Cannabis Dependence, Alcohol Dependence
Pharmacological Treatment of Comorbid Alcohol and Marijuana Withdrawal and Dependence
The primary aim of the supplemental study is to provide POC testing of aprepitant as a treatment for comorbid alcohol and cannabis dependence.
- Conditions
- Cannabis Dependence, Alcohol Dependence, Cannabis Use Disorder, Alcohol Use Disorder
- Trial name
- NCT02210195
- Testing
- aprepitant, Manual-guided behavioral counseling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Scripps Research Institute
Cannabis Dependence, Harmful Use
Cannabis Abstinence and Neurocognitive Assessment in Adolescence
Cannabis Abstinence and Neurocognitive Assessment in Adolescence
- Conditions
- Cannabis Dependence, Harmful Use, Cognitive Assessment
- Trial name
- CANAA (NCT07160153)
- Testing
- Neurocognitive assessment, Urine toxicological assessment
- Where
- Czechia
- Volunteers
- 29 people
- Sponsor
- University Hospital Pilsen
Marijuana Dependence
Pregnenolone and Marijuana Dependence
The cannabinoid delta 9-tetrahydrocannabinol (THC) is the primary psychoactive component of marijuana. THC is believed to be a significant factor in the addictive potential associated with marijuana use.
- Trial name
- NCT02439814
- Testing
- Pregnenolone
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Medical University of South Carolina
Marijuana Use, Marijuana Dependence
Testing the Efficacy of an Online Treatment Program for Heavy Cannabis Use
Cannabis is a frequently-used psychoactive substance. While the majority of individuals can use cannabis without experiencing problems, a small minority of people develop cannabis problems.
- Trial name
- NCT04965012
- Testing
- Online CBT with MET treatment, CBT without MET treatment
- Where
- 2 sites in Canada
- Volunteers
- 152 people
- Sponsor
- York University
Marijuana Dependence
Buspirone Treatment for Marijuana Dependence
Marijuana is the most commonly used illicit drug, yet few clinical trials have evaluated pharmacotherapy treatments for marijuana dependence.
- Trial name
- NCT00875836
- Testing
- Buspirone
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Medical University of South Carolina
Marijuana Dependence
Hormones and Reduction in Co-users of Marijuana and Nicotine
The purpose of this study is to examine the role of progesterone (a naturally occurring hormone found in both men and women) on reducing marijuana use.
- Trial name
- NCT02579421
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cannabis, Cannabis Intoxication
Do Adolescents and Adults Differ in Their Acute Response to Cannabis?
The acute effects of cannabis may differ between adolescents and adults. Furthermore, these effects may be tempered by the presence of cannabidiol.
- Conditions
- Cannabis, Cannabis Intoxication, Cannabis Use, Cannabis Dependence
- Trial name
- CannTeenA (NCT04851392)
- Testing
- Cannabis with delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), Cannabis with THC without CBD
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University College, London
Cannabis Use Disorder
Psilocybin-assisted Treatment for Cannabis Use Disorder
This pilot study will evaluate the therapeutic potential of psilocybin in people with Cannabis Use Disorder (CUD). This study will examine the impact of psilocybin treatment on cannabis use and related variables in 12 people with…
- Trial name
- NCT06660381
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Johns Hopkins University
Marijuana Smoking
Nabilone & Marijuana Addiction
Safety of Nabilone in reducing marijuana craving
- Trial name
- NCT01025700
- Testing
- Cesemat
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of British Columbia
Cannabis, Dependence
Antagonist-Elicited Cannabis Withdrawal
Background: Rimonabant, a CB1 receptor antagonist, blocks effects of cannabinoids and, in dependent animals, elicits cannabinoid withdrawal. No studies have examined rimonabantelicited cannabis withdrawal in humans.
- Trial name
- NCT01041170
- Testing
- THC, Rimonobant, Rimonabant
- Where
- 2 sites in United States
- Sponsor
- National Institute on Drug Abuse (NIDA)
Psychotic Disorders, Cannabis Use Disorder
Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric Controls With Cannabis Use
Cognitive impairment is well established in people with psychosis and is associated with cannabis use. The current study will investigate the neurobiological basis of cognitive change associated with 28-days of cannabis…
- Conditions
- Psychotic Disorders, Cannabis Use Disorder, Cannabis Dependence, Cannabis Use
- Trial name
- NCT05445180
- Testing
- Contingency management
- Where
- Canada
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Marijuana Dependence
The Effect of Marijuana and Prescription Medications in Mood, Performance and Sleep
Heavy marijuana users report experiencing trouble sleeping when they try to quit, but this has not been carefully studied. This research is being done to learn more about sleep function in heavy marijuana users, and to determine…
- Trial name
- NCT00893269
- Testing
- eszopiclone, ramelteon, zolpidem
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cannabis Dependence
Efficacy of Community Reinforcement Approach (CRA) in the Treatment of Cannabis Users
Substance abuse is not a new phenomenon in Pakistan. Its prevalence is increasing day by day due to multi-factorial reasons including psychological, cultural, biological, environmental, social and personal factors.
- Trial name
- Lifecare (NCT04513756)
- Testing
- Community Reinforcement Approach
- Where
- 2 sites in Pakistan
- Volunteers
- 120 people
- Sponsor
- International Islamic University, Islamabad
Cannabis Use Disorder, Cannabis Dependence
N-acetylcysteine for the Treatment of Cannabis Dependence: Working Mechanisms
This study investigates the effects of repeated NAC administration on glutamate concentrations in the anterior cingulate cortex (ACC), on neurocognitive functioning, and on neuro-inflammatory parameters in adult…
- Trial name
- NCT03221231
- Testing
- N-acetylcysteine, Magnetic Resonance Imaging, Neurocognitive measures
- Where
- Belgium
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Cannabis Dependence, Nicotine Dependence
Cognitive Behavioral Therapy and the Nicotine Transdermal Patch for Cannabis Dependence and Nicotine Dependence
The investigators are conducting a Stage 1 pilot feasibility study at McLean Hospital to develop and refine a Cognitive Behavioral Therapy (CBT) intervention.
- Trial name
- CBT-MJ-NIC (NCT01292642)
- Testing
- Cognitive Behavioral Therapy, Nicotine Replacement Therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mclean Hospital
Marijuana Dependence
Marijuana Treatment Project - 3
The goal of this research is to improve treatment outcome for marijuana-dependent individuals. The current study builds on the findings of our prior NIDA-funded marijuana treatment study in which improved client outcomes were…
- Trial name
- MTP-3 (NCT00107588)
- Testing
- Reinforcement for homework completion, Reinforcement for Abstinence, Case Management
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- UConn Health
Cannabis Dependence
Interactions Between Physical Activity and Cannabis Use in Adults
In this study the investigators will explore the relationship between physical activity and cannabis use. The investigators will compare regional brain activation detected by imaging technique(fRMI) before and after exercise in…
- Trial name
- NCT00838448
- Testing
- Exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Cocaine Dependence
Randomized, Double-blind, Placebo-controlled Cannabis Extract x Placebo for Cocaine Addicts
2.1. General To evaluate the efficacy and safety of a Cannabis sativa extract (CBD (Cannabidiol) + up to 0.3% THC (Delta-9-tetrahydrocannabinol)), compared to placebo, in the treatment of cocaine/crack use disorder. 2.2.
- Trial name
- NCT06159387
- Testing
- Cannabis Extract Oil SR Capsule
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital