Clinical trials: Cannabis User
Substance Abuse, Depression
CONNECT for Depressed Cannabis Users Trial
The purpose of this study is to test the usefulness of a computer-assisted intervention for depressed cannabis users by combining peer and therapist social network support via Facebook that uses the techniques of cognitive…
- Trial name
- CONNECT (NCT03727659)
- Testing
- SHADE therapy + CONNECT FaceBook support
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of California, Los Angeles
Cannabis
Transcranial Magnetic Brain Stimulation to Reduce Cannabis Use in Heavy Cannabis Users
The growing legalization of cannabis across the U.S. is associated with increases in cannabis use, and accordingly, an increase in the number of individuals with cannabis use problems, including cannabis use disorder (CUD).
- Trial name
- iCURE (NCT05401929)
- Testing
- iTBS
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Duke University
Cannabis Use, Opioid Consumption
A Comparison of Post-Operative Analgesia Requirements In Recreational Cannabis Users Versus Cannabis Naïve Inflammatory Bowel Disease Patients
Cannabis is a drug that is widely used for recreational purpose. In most patients undergoing surgery, opioids are the most widely used mode of pain relief, during and following surgery.
- Trial name
- NCT04055662
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Mount Sinai Hospital, Canada
Marijuana Abuse, Marijuana Dependence
Attempts to Stop/Reduce Marijuana Among Dependent Users
The purpose of the study is to determine why and how marijuana users stop or reduce their marijuana use.
- Trial name
- NCT01039415
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Psychotic Disorder, Marijuana Use
A Cannabis Harm Reduction e-Intervention for Young Cannabis Users With Early Psychosis
Cannabis users who experienced a psychosis are particularly vulnerable to cannabis-related harms, which can include worse psychotic symptoms and more hospitalizations.
- Conditions
- Psychotic Disorder, Marijuana Use, Young Adult
- Trial name
- CHAMPS (NCT04968275)
- Testing
- CHAMPS
- Where
- 5 sites in Canada
- Volunteers
- 101 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Cannabis Use, Harm Reduction
Testing the Effects of Cann'App, a Digital Intervention for Cannabis Harm Reduction
The goal of this clinical trial is to learn if a digital web application can prevent the risks related to cannabis use among adult regular cannabis users who are enrolled in a pilot trial for cannabis sales regulation conducted…
- Trial name
- Cann'App (NCT07157540)
- Testing
- Personalized Feedback on Cannabis Protective Behavioral Strategies, Cannabis Use, Cannabis Expenditures, and Cannabis-Related Consequences (PF), Imagining the Future Using Counterfactual Thinking and Episodic Future Thinking (IMAGIN), Behavioral Economics-Informed Exercises to Increase Motivation to Engage in Substance-Free Activities (SFAS)
- Where
- Switzerland
- Volunteers
- 565 people
- Sponsor
- Jacques Gaume
Cannabis Dependence
Neural Indices Associated With Relapse in Cannabis Dependence
The aim of this fMRI study is to investigate neural indices of relapse in cannabis dependence. The development and maintenance of drug addictions have been associated with deficits in cognitive control, craving and impaired…
- Trial name
- NCT02801422
- Testing
- fMRI
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Cannabis Dependence
Improving Substance Use and Clinical Outcomes in Heavy Cannabis Users With Quetiapine
Cannabis is the most used illicit substance in the United States. Previous studies suggest that atypical antipsychotics decrease the frequency and the amount of substance use in subjects with and without psychotic illness.
- Trial name
- CD (NCT01153490)
- Testing
- Behavioral Intervention
- Where
- 2 sites in United States
- Volunteers
- 124 people
- Sponsor
- Northwell Health
Cannabis Dependence
Fixed or Self-Titrated Dosages of Sativex on Cannabis Users
The purpose of this study is to to demonstrate the feasibility and tolerability of the use of Sativex in cannabis dependent individuals and to assess the effects of fixed or self titrated dosages of SATIVEX®…
- Trial name
- NCT01748799
- Testing
- Sativex
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Centre for Addiction and Mental Health
Cannabis Use Disorder
Evaluation of a Brief Computerized and Smart Phone-based Intervention for Stress in Regular Cannabis Users
The prevalence of daily cannabis use and Cannabis Use Disorder (CUD) has increased in the United States over the past two decades.
- Trial name
- DISC (NCT06085222)
- Testing
- Emotional Engagement Distress Tolerance Intervention, Health Education Intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Florida State University
Opioid-use Disorder, Cocaine Use Disorder
Feasibility and Validation of a Standard Phenotyping Assessment Battery
The overall goal of this project is to collect preliminary data on psychosocial measures and behavioral performance comparing individuals with Opioid Use Disorder, Cocaine Use Disorder, dual diagnosis of Opioid and Cocaine Use…
- Conditions
- Opioid-use Disorder, Cocaine Use Disorder, Marijuana Use Disorder, Healthy Controls
- Trial name
- PhAB (NCT03495869)
- Where
- United States
- Volunteers
- 368 people
- Sponsor
- Virginia Commonwealth University
Cannabis Use
Electrophysiological Study of the Functioning of Magnocellular Visual Pathway in Regular Cannabis Users
This study will evaluate the impact of regular use of cannabis on the spatial sensitivity of magnocellular system (visual event-related potential, visual ERP).
- Trial name
- CAUSA MAP (NCT02864680)
- Testing
- Electroretinography, Contrast sensitivity test during Electroencephalography, Visual simultaneity test during Electroencephalography
- Where
- France
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Memory
Galantamine Effects on Cognitive Function in Marijuana Users
To evaluate galantamine's effects on cognitive performance in marijuana users. Galantamine, an acetylcholine esterase inhibitor, is approved for treatment of Alzheimer's disease.
- Trial name
- NCT00969696
- Testing
- Galantamine
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yale University
Cocaine Dependence, Cocaine Use Disorder
Neurobehavioral Measurement of Substance Users in Outpatient Treatment Setting
This study was an internal program effectiveness evaluation of the effects of a four-session weekly individualized cognitive therapy program (called the "Mind Freedom Plan" (MFP)) on substance use outcomes and substance abuse…
- Conditions
- Cocaine Dependence, Cocaine Use Disorder, Opiate Dependence, Opioid-use Disorder
- Trial name
- NCT03662529
- Testing
- Four-Session Mind Freedom Plan, Treatment as usual therapy
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Cannabis Intoxication
Exploring The Effect Of Cannabidiol On Cannabis Tolerance Using A Novel Vaporiser Device In Heavy Users (Stage 1)
Cannabis contains delta-9-tetrahydrocannabinol (THC), which causes intoxication. People who use cannabis frequently often develop tolerance, meaning they need to use more THC to feel the same effects.
- Trial name
- ENDURANCE (NCT07471347)
- Testing
- delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- King's College London
Cannabis Dependence
Social and Emotional Brain Function in Cannabis Users
The aim of this functional magnetic resonance imaging (fMRI) study is to find out whether and how social and emotional brain function are altered in dependent cannabis users relative to healthy non-using control subjects after a…
- Trial name
- NCT02711371
- Testing
- fMRI
- Where
- Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Cannabis, Abuse Liability
Repeated CBD Administration and Cannabis Outcomes
This outpatient study examines how cannabidiol (CBD) affects the behavioral and pain-relieving effects of cannabis.
- Conditions
- Cannabis, Abuse Liability, Experimental Pain in Healthy Human Participants
- Trial name
- NCT07434895
- Testing
- Cannabidiol, Medium Dose, Cannabidiol, Higher Dose, Active Inhaled Cannabis
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Hannah Harris
Opioid Use Disorder
Evaluation of the Interactions of Cannabidiol (CBD) With Morphine
The purpose of this study is to analyze drug-drug interactions of CBD on co-administered Morphine as first step in understanding CBD-opioid interactions.
- Trial name
- NCT05143424
- Testing
- Morphine Sulfate
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cannabis Users
Intracranial Arterial Stenosis and Resin of Cannabis Use
There is an association between intracranial arterial stenosis and ischemic stroke in young adults. The aim of this study is to evaluate the prevalence of intracranial arterial stenosis in asymptomatic regular resin of cannabis…
- Trial name
- NCT02246140
- Testing
- Cerebral MRI and MRA
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Occasional (1-2 Joints Per Week) and Chronic (1-2 Joints Per Day) Cannabis Users
Study of the Relationship Between Dose-concentration-effect of Delta-9-tetrahydrocannabinol (THC) and the Ability to Drive in Chronic or Occasional Cannabis Users
Study of the effects of smoked cannabis consumption on performance on a driving simulator and reaction time. The study aims to explore the relationship between concentrations of cannabis in the blood, driving performance and…
- Trial name
- VIGICANN (NCT02061020)
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris