Clinical trials: Carbohydrates
Pediatric Obesity, Diet, Food, and Nutrition
Reducing Sugar-sweetened Beverage Consumption Among Children
Lowering sugar-sweetened beverage (SSB) consumption is a central component of lifestyle behavior change aimed at preventing and managing obesity, yet effective reduction of SSB intakes has been met with many challenges.
- Trial name
- NCT04025060
- Testing
- Commercially-available caffeine-free soda, Carbonated water, Regular soda
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- George Washington University
Obesity Type I and II, Obesity and Overweight
Metabolic Investigation, Physical Performance, Physical Training At Different Times of the Day in Obese Women
Obesity is a disease characterized by the accumulation of adipose tissue, which is multifactorial and can be caused by environmental, social, behavioral, biological and genetic issues, and affects people health and well-being.
- Trial name
- MOT-time (NCT06601660)
- Testing
- Morning Physical Training, Night Physical Training, No intervention
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- State University of Minas Gerais
Lafora Disease
Ketogenic Diet in Lafora Disease
This study will examine the effect of a restricted-carbohydrate diet (ketogenic diet) on Lafora disease-a severe neurological disease in which brain cells die because of abnormal accumulation of glucose (a type of sugar).
- Trial name
- NCT00007124
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
High Whole Grain and Low Sugar, Medium Whole Grain and Low Sugar
Health Effects of Grain Foods in Adults
This study will assess the effects of eating whole grain foods versus refined grain foods with different amounts of added sugar.
- Conditions
- High Whole Grain and Low Sugar, Medium Whole Grain and Low Sugar, Low Whole Grain and Low Sugar, Low Whole Grain and High Sugar
- Trial name
- NCT06339879
- Testing
- High Whole Grain, Low Sugar, Low Whole Grain, Low Sugar, High Whole Grain, High Sugar
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Purdue University
Type 2 Diabetes Mellitus, Cardiovascular Disease
The Effect of a Traditional Dietary Intervention on Diabetes Mellitus and Cardiovascular Disease Risk Factors in a First Nation Community: A Pilot Study
The purpose of this study is to evaluate whether or not a traditional First Nations diet (high protein) and/or a dietary intervention based upon current Canadian dietary recommendations (high carbohydrate/high fiber) effects risk…
- Conditions
- Type 2 Diabetes Mellitus, Cardiovascular Disease, Obesity
- Trial name
- SLHDP (NCT00707460)
- Testing
- Dietary Intervention (Macronutrient composition)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Inflammation, Insulin Sensitivity
Sugar-sweetened Beverages Influence Benefits of Exercise in Overweight Adults
The objective of this study was to determine how metabolic and inflammatory effects of physical exercise in overweight individuals are altered when sugar-sweetened beverages (SSB) are consumed after physical exercise.
- Trial name
- NCT03576703
- Testing
- Exercise with and without SSB ingestion
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Montana State University
Genetic Disease, Inborn Errors of Metabolism
Identification and Characterization of Novel Non-Coding Variants That Contribute to Genetic Disorders
The goal of this study is to identify and characterize novel non-coding and splicing variants that may contribute to genetic disorders.
- Conditions
- Genetic Disease, Inborn Errors of Metabolism, Glycogen Storage Disease, Lysosomal Storage Diseases
- Trial name
- NCT04399694
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Duke University
Aneurysmal Subarachnoid Hemorrhage
Efficacy and Safety Study of a Low-carbohydrate Tube Feed in Critically Ill Patients Under Insulin Therapy
The purpose of this study is to determine the efficacy and safety of a diabetes-specific tube feed in comparison to an isocaloric, isonitrogenous standard enteral formula in critically ill patients receiving insulin treatment for…
- Trial name
- NCT02503527
- Testing
- Diben 1.5 kcal HP, Fresubin HP Energy Fibre (1.5 kcal)
- Where
- Austria
- Volunteers
- 28 people
- Sponsor
- Fresenius Kabi
Mucolipidosis Type IV
The Natural History of Mucolipidosis Type IV
The purpose of this study is to define the natural history of Mucolipidosis Type IV and identify potential clinical outcome measures.
- Trial name
- NCT01067742
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Baylor Research Institute
Cognitive Performance, Food Cravings
Cognitive Function and Cue-Reactivity Study
We are interested in testing differences in cognitive function and food reactivity at various time points in individuals following low and high carbohydrate diets.
- Trial name
- NCT00194246
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Temple University
Obesity Prevention, Diabetes Prevention
Types of Starch and Their Effect on Blood Glucose, Appetite and Food Intake
The investigators hypothesize that different types of starch vary in their effects on appetite, blood sugar and food intake. In this study, subjects consumed five soups containing 50 g of whole grain, high amylose corn, regular…
- Trial name
- NCT00980941
- Testing
- soup with or without starch
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Type 1 Diabetes
Supporting Meal Management in Type 1 Diabetes
Carbohydrate count marks the cornerstone of Type 1 Diabetes management. Eventhough it is a crucial task, it is burdensome and prone to error.
- Trial name
- SUMMIT1 (NCT05671679)
- Testing
- SNAQ app, Traditional carbohydrate counting
- Where
- Switzerland
- Volunteers
- 44 people
- Sponsor
- Lia Bally
Glycogen Storage Disease Type V, McArdle Disease
Sodium Valproate for GSDV
McArdle disease is a metabolic myopathy characterised by the absence of glycogen phosphorylase in skeletal muscle. Sodium Valproate is part of a group of drugs known as histone deacetylase inhibitors, which have a direct effect…
- Trial name
- NCT03112889
- Testing
- Sodium Valproate
- Where
- 2 sites in Denmark, United Kingdom
- Volunteers
- 8 people
- Sponsor
- University College, London
Local Anesthesia
Effect of a Candy Flavoring Before Local Anesthesia on Anxiety and Pain Perception in Children
This is a randomized clinical trial that aimed to test the effect of using sugar-free flavors as a sensory distraction technique during local anesthesia on pain perception when compared to a negative control group.
- Trial name
- NCT05727527
- Testing
- Local Anesthesia 1, Local Anesthesia 2
- Where
- Jordan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Over Weight, Obesity
Low-Carbohydrate Diet Intervention on Body Weight
The primary aim of this study is to determine the adherence of low- carbohydrate among Chinese. Then compare the effect of low-carbohydrate and traditional Chinese but restricted-calories diet on weight loss and metabolic traits.
- Trial name
- NCT01358890
- Testing
- low carbohydrate diet, Calories restricted diet
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Chinese Academy of Sciences
Diabetes Mellitus, Type 2
A Research Study Comparing RYBELSUS® to Other Blood Sugar Lowering Tablets in People Living in America With Type 2 Diabetes (REALYSE)
This study is comparing the medicine RYBELSUS® to other medicines in people with type 2 diabetes who need extra treatment. All medicines used in this study are tablets which lower blood sugar in people with type 2 diabetes.
- Trial name
- REALYSE (NCT05035082)
- Testing
- semaglutide, oral glucose-lowering medications (commercially available)
- Where
- 25 sites in United States
- Volunteers
- 1,018 people
- Sponsor
- Novo Nordisk A/S
Primary Immune Deficiency Disorders, Hemophagocytic Lymphohistiocytosis
Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases
The purpose of this study is to determine a safe dose of BPX-501 gene modified T cells infused after a haplo-identical stem cell transplant to facilitate engraftment and the safety of Rimiducid (AP1903) on day 7 to prevent GVHD.
- Conditions
- Primary Immune Deficiency Disorders, Hemophagocytic Lymphohistiocytosis, Inherited Bone Marrow Failure Syndrome, Hemoglobinopathies
- Trial name
- NCT02231710
- Testing
- BPX-501 and Rimiducid
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Bellicum Pharmaceuticals
Severe Combined Immunodeficiency, Malignancy, Hematologic
Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked Products
This protocol (GENEFU) provides a mechanism for the 15-year followup period that the FDA requires for all participants in gene transfer protocols and assures that adequate followup can be maintained for a wide variety of…
- Conditions
- Severe Combined Immunodeficiency, Malignancy, Hematologic, Neuroblastoma, Neoplasm
- Trial name
- NCT00695279
- Testing
- Venipuncture
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- St. Jude Children's Research Hospital
Healthy, Obese
The Impact of Modified Wheat Bran on Carbohydrate Fermentation in the Colon in Healthy and Obese Subjects
During this project the effect of modified wheat bran on colon health and systemic health will be evaluated in a long-term intervention study in healthy and obese subjects.
- Trial name
- NCT02796989
- Testing
- Wheat bran
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Cardiovascular Diseases, Chronic Disease
Nutrigenomics Diet Intervention Study Comparing Effects of Western and Balanced Diet in Healthy Subjects
Diet macronutrient relative composition, quality and quantity determines lifestyle disease, including cardiovascular disease, development.
- Trial name
- Foodgene (NCT00733018)
- Testing
- "Western" versus "balanced" macro nutrient diet composition
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology