Clinical trials: Carbon Dioxide
Partial Pressure of Carbon Dioxide
Correlation Between Peripheral and Central Venous Blood Partial Pressure of Carbon Dioxide in Critical Ill Patients
Observational study to analyze correlation between partial pressure of carbon dioxide from blood obtained from peripheral and central veins
- Trial name
- NCT03269448
- Testing
- Peripheral venous blood sampling
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Ramathibodi Hospital
Neurosurgery
Correlation of PaCO2 to the Inspired and Expired Oxygen Gradient
The purpose of this study is to evaluate whether a correlation exists between the partial pressure of carbon dioxide existing within arterial blood and the gradient between inhaled and exhaled fractions of oxygen.
- Trial name
- O2 Fraction (NCT01513213)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Swedish Medical Center
Critically Ill, Hypovolemia
Fluid Responsiveness After CArdiac Surgery Study
Study Design: Prospective observational study Study Location: Liverpool Hospital Intensive Care Unit, South Western Sydney Local Health District, Sydney, Australia.
- Trial name
- FRACAS (NCT02841943)
- Where
- Australia
- Volunteers
- 102 people
- Sponsor
- South West Sydney Local Health District
Hyperventilation, Chronic Idiopathic Hyperventilation
Normalizing CO2 in Chronic Hyperventilation by a Novel Breathing Mask: A Pilot Study
Background: Chronic Idiopathic Hyperventilation (CIH) is a form of dysfunctional breathing which has proven hard to treat effectively.
- Conditions
- Hyperventilation, Chronic Idiopathic Hyperventilation, Dysfunctional Breathing, Respiratory Alkalosis
- Trial name
- HVMASKE (NCT01575665)
- Testing
- Partial Rebreathing Mask
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- University of Aarhus
Genitourinary Syndrome of Menopause (GSM), Breast Cancer Female
Genitourinary Syndrome of Menopause in Breast Cancer
This randomized, single-blind clinical trial will compare the effectiveness of multimodal pelvic floor physiotherapy (PPT) and fractional CO2 vaginal laser therapy in reducing genitourinary syndrome of menopause (GSM) symptoms…
- Trial name
- PILME (NCT06721936)
- Testing
- Multimodal pelviperineal physioterapy group, Laser CO2 Therapy group
- Where
- Spain
- Volunteers
- 182 people
- Sponsor
- University of Alcala
Pneumoperitoneum
A Trial of Supplemental CO2 Versus Room Air in Percutaneous Endoscopic Gastrostomy
The investigators hypothesize that using carbon dioxide for PEG placement versus using room air will decrease post-procedure pneumoperitoneum as well as improve post-procedure bloating/pain, and waist circumference.
- Trial name
- NCT02619656
- Testing
- CO2 insufflation, Ambient air insufflation
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Utah
Local Anesthesia of the Skin.
Fractional Laser Assisted Delivery of Anesthetics
The purpose of this study is to assess the efficacy of fractional CO2 laser assisted delivery of topically applied anesthetics (articaine hydrochloride 40 mg/ml and epinephrine 10 μg/ml solution and EMLA cream) regarding to…
- Trial name
- NCT02246179
- Testing
- AFXL, AHES, EMLA cream
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Netherlands Institute for Pigment Disorders
Cardiac Physiology, Cardiac Output
The Feasibility and Accuracy of Exhaled CO2 to Measure Cardiac Output in Ventilated Patients Without Tracheal Intubation
The purpose of this study is to test the accuracy of a new noninvasive way to measure how much blood our heart pumps per minute.
- Trial name
- NCT00783679
- Testing
- NICO device
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Acute Respiratory Failure With Hypoxia
pRotective vEntilation With Veno-venouS Lung assisT in Respiratory Failure
This is a trial of a new way of treating patients with respiratory failure. The investigators propose to deliver a multi-centre clinical trial to determine whether veno-venous extracorporeal carbon dioxide removal (VV-ECCO2R) and…
- Trial name
- REST (NCT02654327)
- Testing
- VV-ECCO2R to enable lower tidal volume mechanical ventilation
- Where
- United Kingdom
- Volunteers
- 1,120 people
- Sponsor
- Belfast Health and Social Care Trust
High-Frequency Ventilation
HFOV With Intermittent Sigh Breaths in Neonate: Carbon Dioxide Level
The goal of this clinical trial is to the short-term effects of sigh breaths during High-frequency oscillatory ventilation (HFOV) in neonate undergoing mechanical ventilation.
- Trial name
- SighCO2 (NCT05682937)
- Testing
- HFOV-sigh
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Prince of Songkla University
Keloid
A Study Using Fractional Carbon Dioxide and Long Pulsed Neodymium-yttrium Aluminum Garnet Lasers in Treatment of Keloids
clinical comparative study comparing the effectiveness of fractional CO2, long pulsed Nd YAG and their combination in collagen remodeling in keloid clinically, biochemically and histopathologically
- Trial name
- NCT03460431
- Testing
- fractional CO2 laser 10,600nm, Nd YAG laser1064 nm
- Volunteers
- 30 people
- Sponsor
- Cairo University
Hydration, Carbon-dioxide Laser
Effectiveness and Safety of a Hydrating Gel Containing Polyvinyl Pyrrolidine, Algin and Hyaluronic Acid Applied After and Without Fractional CO₂ Laser Therapy
The purpose of this interventional study is to evaluate the effectiveness and safety of a hydrating gel containing aqua, carrageenan, polyvinyl pyrrolidone, algin, gellan gum, and hyaluronic acid.
- Conditions
- Hydration, Carbon-dioxide Laser, Laser Therapy, Hydrogel
- Trial name
- NCT07639151
- Testing
- CO2 Fractional Laser, Hydrogel
- Where
- Indonesia
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Brain Death
ORI and ETCO₂ Relationship With Arterial Blood Gas During Apnea Test
This observational study aims to evaluate the relationship between the Oxygen Reserve Index (ORI) and End-Tidal Carbon Dioxide (ETCO2) values with arterial blood gas parameters in patients undergoing the apnea test for the…
- Trial name
- NCT06983990
- Testing
- No intervention (observational monitoring only)
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Benign Neoplasm of Cervix Uteri, Gynecological Laparoscopy
The Effects of CO2 Pneumoperitoneum at Different Temperature in Laparoscopic Surgery
Objective: It is recommended to heat and humidify CO2 in laparoscopic surgery to prevent postoperative pain and hypothermia but information about its effects on hemodynamic and respiratory parameters is limited.
- Trial name
- NCT04508387
- Testing
- Group HH (heated-humidified)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ege University
Traumatic Brain Injury, Aging Disorder
Carbon Dioxide Administration and Brain Waste Clearance
The current study tests whether different exposures to carbon dioxide (CO2) can safely result in the increased movement of proteins from the brain into the blood.
- Conditions
- Traumatic Brain Injury, Aging Disorder, Magnetic Resonance Imaging (MRI)
- Trial name
- COPETBI (NCT07357090)
- Testing
- Hypercapnia task performed during fMRI
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Andrew Mayer
COVID-19 Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation Complication
Correlation Between PaCO2 and Respiratory Effort in Patients With COVID-19 With Extracorporeal Membrane Oxygenation
Excessive respiratory effort may cause self-inflicted lung injury (SILI) and inspiratory muscle injuries , stimulate desynchronization between the patient and ventilator , and worsen the perfusion of extrapulmonary organs .
- Conditions
- COVID-19 Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation Complication, Respiratory Effort-Related Arousal
- Trial name
- NCT05882474
- Testing
- PaCO2
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Peking Union Medical College Hospital
Acute Respiratory Failure
Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults
This study will compare the sensitivity and specificity of waveform capnography versus colorimetric carbon dioxide detection to identify tracheal placement of the endotracheal tube during intubation of critically ill adults.
- Trial name
- WAVE (NCT06934876)
- Testing
- Colorimetric carbon dioxide (CO2) detection, Waveform capnography
- Where
- 9 sites in United States
- Volunteers
- 2,092 people
- Sponsor
- Brian Driver
Cholecystolithiasis
Warmed, Humidified Carbon Dioxide Insufflation vs Standard Carbon Dioxide in Laparoscopic Cholecystectomy
The purpose of this study is to determine the effect of warmed, humidified carbon dioxide Insufflation vs standard carbon dioxide in laparoscopic cholecystectomy.
- Trial name
- NCT01667848
- Testing
- Optitherm® device activated, Optitherm® device inactivated
- Where
- Austria
- Volunteers
- 148 people
- Sponsor
- Kepler University Hospital
Obstructive Sleep Apnea
Respiratory Drive on Obstructive Apnea
This study is being conducted to determine whether inhaling exhaled carbon dioxide is effective for the treatment of sleep apnea.
- Trial name
- NCT01961648
- Testing
- Rebreathing bag, Mask
- Where
- 2 sites in Canada
- Volunteers
- 13 people
- Sponsor
- University of Manitoba
Death, Sudden, Cardiac, Perfusion Index
Is the Perfusion Index an Accurate Predictor of Return of Spontaneus Circulation in Out-of-hospital Cardiac Arrest
The purpose of this pilot feasibility study is to evaluate the ability of the Perfusion Index to predict the return to spontaneous circulation of the out-of-hospital cardiac arrest patient during cardiopulmonary resuscitation.
- Conditions
- Death, Sudden, Cardiac, Perfusion Index, Return of Spontaneous Circulation
- Trial name
- NCT05383885
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre