Clinical trials: Carcinoma, Breast
Breast Cancer
Evaluation of Breast Cancer Screening Program at Assiut Governorate
1. To evaluate the ability of breast clinical examination as screening tool to detect early and advanced stages of breast cancer. 2.
- Trial name
- NCT06403917
- Testing
- Evaluation of breast screening
- Volunteers
- 15,000,000 people, healthy volunteers welcome
- Sponsor
- Assiut University
Breast Cancer, Aromatase Inhibitors
Effect of Aromatase Inhibitors on Ultrasonographic Measurements and Static and Dynamic Balance Scores in Breast Cancer
To evaluate the effects of aromatase inhibitors on lower extremity ultrasonographic measurements, static and dynamic balance scores in breast cancer patients using aromatase inhibitors
- Conditions
- Breast Cancer, Aromatase Inhibitors, Balanced
- Trial name
- NCT06184074
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Breast Cancer, Osteoporosis
Zoledronate in Preventing Bone Loss in Premenopausal Women Receiving Chemotherapy After Surgery For Early Stage Breast Cancer
RATIONALE: It is not yet known whether zoledronate is effective in preventing bone loss in premenopausal women who are receiving adjuvant chemotherapy after undergoing surgery for early stage breast cancer.
- Trial name
- NCT00049452
- Testing
- zoledronic acid
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Herbert Irving Comprehensive Cancer Center
Breast Cancer
Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Breast Cancer
The purpose of this study is to evaluate the safety and time to progression of HLA-A*0201 restricted epitope peptides VEGFR1 and VEGFR2 emulsified with Montanide ISA 51 in advanced breast cancer patients.
- Trial name
- NCT00677326
- Testing
- VEGFR1 and VEGFR2
- Where
- Japan
- Volunteers
- 1 people
- Sponsor
- Tokyo University
Breast Cancer
Docetaxel and Ifosfamide in Treating Women With Metastatic Breast Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of docetaxel and ifosfamide in treating women who have…
- Trial name
- NCT00026078
- Testing
- docetaxel, ifosfamide
- Where
- 8 sites in Argentina, Mexico
- Volunteers
- 42 people
- Sponsor
- Grupo Oncologico Cooperativo del Sur
Breast Cancer, Metastatic Castration-resistant Prostate Carcinoma
Lean Body Mass as a Determinant of Docetaxel Pharmacokinetics and Toxicity
Docetaxel is used as a first line anti-cancer drug in the treatment of several cancers, mainly breast- and metastatic castration-resistant prostate carcinoma.
- Trial name
- LEANDOC (NCT01621425)
- Testing
- Lean body mass, Total body weight, bloodsampling
- Where
- 2 sites in Netherlands
- Volunteers
- 25 people
- Sponsor
- Radboud University Medical Center
Breast Cancer
Gemcitabine Hydrochloride and Genistein in Treating Women With Stage IV Breast Cancer
RATIONALE: Drugs used in chemotherapy, such as gemcitabine hydrochloride and genistein, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00244933
- Testing
- genistein, gemcitabine, Tumor biopsy
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Breast Cancer
Optical Spectroscopy During Breast Cancer Surgery and Core Needle Biopsy
The objective of the proposed research is to develop new diagnostic modalities based on optical spectroscopy (auto fluorescence, absorption, and scattering) for the diagnosis of breast cancer and test its performance as an…
- Trial name
- NCT00734838
- Testing
- High Resolution Microendoscope
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Duke University
HER 2 Positive Advanced Breast Cancer, Breast Cancer
Phase Ib/II Study of Zanidatamab Plus Tucatinib and Chemotherapy in HER2-Positive Advanced Breast Cancer
The JAZMINE study is a multicenter, open-label, non-comparative, phase Ib/II clinical trial to evaluate safety and preliminary efficacy of zanidatamab in combination with tucatinib and chemotherapy (capecitabine or eribulin…
- Trial name
- JAZMINE (NCT07494448)
- Testing
- Zanidatamab, Tucatinib, Capecitabine
- Volunteers
- 24 people
- Sponsor
- MedSIR
Atypical Ductal Hyperplasia, Ductal Carcinoma in Situ
Excisional Vacuum-Assisted Breast Biopsy
The goal of this prospective cohort study is to evaluate the possibility of vacuum-assisted excisional biopsy (VAE) to completely remove the pathology in case of small lesions for Atypical Ductal Hyperplasia (ADH) and…
- Trial name
- NCT05932758
- Testing
- Vacuum-assisted excisional biopsy, Not excisional biopsy
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- European Institute of Oncology
Breast Cancer
Individuals on Hormone Therapy Breast Cancer Screening Pilot
This investigation is a prospective breast cancer screening study open to all individuals on hormone therapy. Using a mixed methods approach, the study will 1) gather prospective quantitative breast imaging data in conjunction…
- Trial name
- NCT06383026
- Testing
- Breast Cancer Screening, Survey/Interview, Focus Group
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Breast Cancer Female
Cosmetic Outcome, Patient-reported Outcomes, and Reconstruction-related Complications in Breast Cancer Women Treated With or Without Post-mastectomy Radiation Therapy
This study aim to investigate the breast reconstruction outcome after mastectomy with or without radiation therapy from the patient's point of view.
- Trial name
- NCT03523078
- Testing
- Breast reconstructive surgery
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Yonsei University
Aromatase Inhibitor-Associated Musculoskeletal Syndrome, Arthralgia Syndrome
AKU Study - Acupuncture for Aromatase Inhibitor-Induced Musculoskeletal Syndrome
Third-generation aromatase inhibitors (AIs) represent a standard adjuvant endocrine treatment for postmenopausal and high-risk premenopausal women with hormone receptor-positive early breast cancer.
- Conditions
- Aromatase Inhibitor-Associated Musculoskeletal Syndrome, Arthralgia Syndrome, Early Breast Cancer (EBC)
- Trial name
- AKU (NCT07909785)
- Testing
- Manual Acupuncture
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- Masaryk Memorial Cancer Institute
Breast Cancer Detection
Developing Screening Clinical Breast Examination Implementation Strategies in Nigeria
The goal of this observational study is to engage with multilevel stakeholders to collaboratively and to systematically develop a suite of strategies for implementing breast cancer screening using clinical breast examination…
- Trial name
- NCT07080515
- Where
- Nigeria
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Yale University
Breast Neoplasm Female
Peri-gravidic Exposure to Endocrine Disrupting Persistent Organic Pollutants
Breast cancer, the first female cancer, affects one in eight women in her lifetime. The increase and unequal distribution of its prevalence throughout the world, regardless of age and genetic factors (< 10% of cases)…
- Trial name
- SEINPOL (NCT03673150)
- Testing
- non intervention
- Where
- France
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Osteoporosis, Breast Cancer
Effect Of Whole Body Vibration Versus Weight Bearing Exercises On Osteoporosis In Breast Cancer Patients After Chemotherapy
Chemotherapy can damage bone marrow and therefore impair the production of white blood cells, platelets and red blood cells with the resulting anemia and osteoporosis.
- Trial name
- NCT05970250
- Testing
- Whole body vibration group, Weight bearing exercises, vitamin D supplements and calcium
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors
This research trial is testing a combination of two experimental drugs, MSC1936369B (Mitogen-activated protein extracellular signal-regulated kinase (MEK) Inhibitor) and SAR245409 (Phosphatidylinositol 3-kinase (Pi3K)/Mammalian…
- Conditions
- Locally Advanced Solid Tumor, Metastatic Solid Tumor, Breast Cancer, Non Small Cell Lung Cancer
- Trial name
- NCT01390818
- Testing
- MSC1936369B (pimasertib), SAR245409 (PI3K and mTOR inhibitor)
- Where
- 8 sites in United States, Italy and 1 more
- Volunteers
- 146 people
- Sponsor
- EMD Serono
Breast Cancer, Uterine Cancer
Musicotherapy in the Reduction of Fatigue in Women With Breast or Gynecological Cancer Under Radiotherapy
OBJETIVE: To study the influence of musicotherapy in reduction of fatigue related to cancer in patients with breast's or gynecology's cancer, during the radiotherapy treatment.
- Conditions
- Breast Cancer, Uterine Cancer, Ovarian Cancer
- Trial name
- NCT01570218
- Testing
- Music therapy
- Where
- 2 sites in Brazil
- Volunteers
- 164 people
- Sponsor
- Universidade Federal de Goias
Breast Cancer, Age
The Association Between Age-related Peripheral Blood Components and Treatment Efficacy in Breast Cancer
This study is a single-center, prospective/retrospective, observational clinical research designed to compare the differences in peripheral blood components between young and elderly HR+HER2- breast cancer patients, and to…
- Trial name
- NCT06718010
- Testing
- No intervention (observational study)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fudan University
Breast Cancer
Eradication of Malignant Carcinoma in the Breast Tissue
The purpose of this study is to confirm the findings of an early study and expand our knowledge of treating Malignant Carcinoma in the Breast Tissue Using an ATP (Adenosine-5'-Triphosphate) Inhibitor.
- Trial name
- NCT02286778
- Testing
- Acetogenins
- Volunteers
- 60 people
- Sponsor
- Optimal Health Research
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