Clinical trials: Carcinoma Breast
CIPN in Adjuvant Colon Cancer Patients, CIPN in Adjuvant Breast Cancer Patients
Observational STudy to Evaluate the EFfectiveness of OnLife® in Improving CIPN in Patients With Colon or Breast Cancer After End of Adj. Therapy
The objective of this observational study is to evaluate the effectiveness of the dietary supplementation "OnLife" in improving signs and symptoms of chemotherapy-induced peripheral neuropathy (CIPN) in adult patients who have…
- Trial name
- STEFANO (NCT03065478)
- Testing
- OnLife
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Swiss Medical Food AG
Lymphedema
Therapeutical Assessment of Compression Armsleeves for Lymphatic Indications
Examination of therapeutical effects of different types of armsleeves in treating lymphatic diseases after breast cancer surgery during maintenance phase 1. thesis: all types should be equal regarding volume reduction 2.
- Trial name
- BF09-PH-01 (NCT01318785)
- Testing
- Compression Armsleeves
- Where
- 4 sites in Austria, Belgium and 2 more
- Volunteers
- 40 people
- Sponsor
- University Medicine Greifswald
Breast Cancer Female
Non-interventional Study Evaluating Gynecological Impact of Diagnosis and Treatment of Breast Cancer in Patients Younger
Brest cancer is the most common cancer in women in France with 52.000 new cases diagnosed in 2010 including nearly 6.000 women younger than 40.
- Trial name
- ARTEMIS (NCT03470935)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hôpital Privé des Côtes d'Armor (HPCA)
Breast Cancer
Assessment of Ability of Breath Hold for Left-sided Breast Cancer Radiation Therapy to Reduce Side Effects to Heart
The purpose of this research study is to demonstrate that Deep Inspiration Breath Hold (DIBH), the technique used at the University of North Carolina (UNC) for left-side breast cancer radiation therapy, can reduce side effects to…
- Trial name
- NCT01849614
- Testing
- Cardiac SPECT perfusion scan
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Peripheral Nervous System Disorders, Breast Neoplasms
Heading Off Peripheral Neuropathy With Exercise
Chemotherapy for the treatment of breast cancer can affect nerves and muscles leading to loss of sensation in the hands and feet for feeling hot and cold, difficulty walking, and muscle weakness.
- Conditions
- Peripheral Nervous System Disorders, Breast Neoplasms, Chemotherapy
- Trial name
- HOPE (NCT00869804)
- Testing
- Aerobic/ Resistance Exercise Intervention, Attention control
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Nebraska
Breast Cancer
A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Primary Breast Cancer
This study will evaluate the effect of Avastin (15mg/kg iv) in combination with Docetaxel and Xeloda, given as pre-operative therapy to patients with primary breast cancer.
- Trial name
- NCT02005549
- Testing
- bevacizumab [Avastin], docetaxel, capecitabine [Xeloda]
- Where
- Austria
- Volunteers
- 18 people
- Sponsor
- Hoffmann-La Roche
Breast Cancer
Pre-operative Contrast Enhanced CT to Improve Delineation of the Tumorbed in Radiotherapy for Breast Cancer.
Rationale: Whole breast irradiation with 50 Gy after lumpectomy has been shown to reduce the local recurrence rate with a factor 3 to 4.
- Trial name
- NCT00721058
- Testing
- CT-scan
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht Radiation Oncology
Breast Cancer
Marker Technique Comparison in Targeted Axillary Dissection
Comparison of two methods (Magnetic Marker and standard metal clip) used for localisation and extraction of lymph nodes in Targeted Axillary Dissection (TAD) in patients with breast cancer.This Project will investigate and…
- Trial name
- MALLORCA (NCT05173415)
- Testing
- Sirius Pintution, HydroMARK (C) Clip
- Where
- 4 sites in Switzerland
- Volunteers
- 40 people
- Sponsor
- Constanze Elfgen
Breast Cancer
A Study of GDC-0810 Single Agent or in Combination With Palbociclib and/or a Luteinizing Hormone-Releasing Hormone (LHRH) Agonist in Women With Locally Advanced or Metastatic Estrogen Receptor Positive Breast Cancer
This study is a multi-institution, Phase Ia/Ib/IIa open-label, dose-finding, safety, pharmacokinetics (PK), and proof-of-concept study of GDC-0810 as a single agent and in combination with palbociclib and/or LHRH agonist.
- Trial name
- NCT01823835
- Testing
- GDC-0810, LHRH Agonist, Palbociclib
- Where
- 14 sites in United States, Netherlands and 2 more
- Volunteers
- 152 people
- Sponsor
- Genentech, Inc.
Breast Cancer, Colorectal Cancer
Survey of Health Preferences in Cancer Patients (QALY-Cancer)
This study will evaluate health utilities in patients with breast or colorectal cancer.
- Trial name
- QALY-Cancer (NCT03560817)
- Where
- Canada
- Volunteers
- 198 people
- Sponsor
- Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Breast Cancer
Reliability and Reproducibility of Bandaging in Breast Cancer
Functional Compressive Bandage (ECF) is a widely used therapeutic resource in the control of lymphedema resulting from the treatment of breast cancer, however, the effects inherent to the technique depend on the quality of the…
- Trial name
- NCT04076033
- Testing
- functional compressive bandage
- Where
- Brazil
- Volunteers
- 23 people
- Sponsor
- Elaine Caldeira de Oliveira Guirro
Metastatic Breast Cancer
Stereotactic Body Radiation Therapy Combined With Anti-PD-1 Antibody in Metastatic Triple Negative Breast Cancer
The objective of this study is to evaluate the safety and tolerance of Stereotactic Body Radiation Therapy Combined With Anti-PD-1 Antibody in Patients in Metastatic Triple Negative Breast Cancer
- Trial name
- NCT03151447
- Testing
- stereotactic body radiation therapy
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Fudan University
Breast Cancer, Nausea
Fosaprepitant Dimeglumine and Granisetron Transdermal System in Preventing Nausea and Vomiting in Patients With Breast Cancer Undergoing Chemotherapy
This clinical trial studies how well fosaprepitant dimeglumine and granisetron transdermal system work in preventing nausea and vomiting in patients with breast cancer undergoing chemotherapy.
- Conditions
- Breast Cancer, Nausea, Vomiting
- Trial name
- NCT01649258
- Testing
- granisetron transdermal system, fosaprepitant dimeglumine, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Southern California
Breast Cancer, Metastatic Cancer
Molecularly Targeted Umbrella Study in Luminal Advanced Breast Cancer
This study is a prospective, single-center, open-label, umbrella-shaped phase II clinical study for patients with HR+/HER2- endocrine-resistant advanced breast cancer.
- Trial name
- MULAN (NCT04355858)
- Testing
- SHR7390, Famitinib, SHR3162
- Where
- China
- Volunteers
- 319 people
- Sponsor
- Fudan University
Breast Cancer, Hot Flashes
Hormone Replacement Therapy in Relieving Menopausal Symptoms in Postmenopausal Women With Previous Stage I or Stage II Breast Cancer
RATIONALE: Hormone replacement therapy may be effective in relieving symptoms of menopause, such as hot flashes, night sweats, and vaginal dryness, without causing a recurrence of breast cancer.
- Conditions
- Breast Cancer, Hot Flashes, Menopausal Symptoms, Osteoporosis
- Trial name
- NCT00079248
- Testing
- therapeutic progesterone, conjugated estrogens
- Where
- United Kingdom
- Sponsor
- Institute of Cancer Research, United Kingdom
Metastatic Breast Cancer
A Study of JNJ-101684362 (HLD-0117) in Patients With Metastatic Breast Cancer
The purpose of this study is to find out the maximum tolerated dose (MTD) and/or recommended dose(s) for expansion (RDEs) of JNJ-101684362 (HLD-0117), to evaluate the safety of JNJ-101684362 (HLD-0117) , and how well the…
- Trial name
- HLD-0117 (NCT07524855)
- Testing
- JNJ-101684362 (HLD-0117)
- Where
- 7 sites in United States, Australia
- Volunteers
- 170 people
- Sponsor
- Janssen Research & Development, LLC
Breast Cancer
Assessment of Automated Breast Ultrasound
The investigators are interested in assessing the value of and comparing the use of automated breast ultrasound (ABUS) (either as a primary screening approach or as a supplementary procedure) with digital breast tomosynthesis…
- Trial name
- NCT02386176
- Where
- United States
- Volunteers
- 598 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Breast Cancer
Light Based Analysis of Developing Breast Tissue in Adolescent Girls: a Feasibility Study
The proposed pilot study attempts to investigate the feasibility of Optical Spectroscopy (OS) as a method to quantify breast tissue composition and density in adolescent females.
- Trial name
- NCT00188591
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Breast Cancer, Ribociclib
A Deep Learning Method to Evaluate QT on Ribociclib
"Deep-learning" is a fast-growing method of machine learning (artificial intelligence, AI) which is arousing the interest of the scientific committee in many medical fields.
- Trial name
- QT-RIBRATING (NCT05623397)
- Testing
- Acquisition of a digitized ECG by four modalities within 20 minutes
- Where
- 4 sites in France
- Volunteers
- 70 people
- Sponsor
- CMC Ambroise Paré
TNBC - Triple-Negative Breast Cancer
Neoadjuvant Fluzoparib in Germline BRCA-mutated Three-negative Breast Cancer Breast Cancer
Although many PARP inhibitors did not improve pCR in neoadjuvant studies, it is not an unchallenged conclusion that TNBC does not benefit from use of PARP inhibitors in neoadjuvant therapy.This study is an open-label, two-cohort…
- Trial name
- NCT05834582
- Testing
- Fluzoparib+Paclitaxel, Epirubicin+Cyclophosphamide
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
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