Clinical trials: Carcinoma of Prostate (Disorder)
Prostate Adenocarcinoma, Stage IIC Prostate Cancer AJCC v8
Testing the Addition of a New Anti-Cancer Drug, Niraparib, to the Usual Treatment (Hormone and Radiation Therapy) for Prostate Cancer With a High Chance of Recurring
This is a phase I-II trial to find the safety and activity of adding a new drug (neraparib) to the usual treatment (radiation combined with male hormone deprivation therapy) in lowering the chance of prostate cancer growing or…
- Conditions
- Prostate Adenocarcinoma, Stage IIC Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8, Stage IIIA Prostate Cancer AJCC v8
- Trial name
- NCT04037254
- Testing
- Gonadotrophin Releasing Hormone, Intensity-Modulated Radiation Therapy, Niraparib
- Where
- 95 sites in United States, Canada
- Volunteers
- 22 people
- Sponsor
- NRG Oncology
Prostate Cancer
Study of Proscavax Vaccine in Patients With Localized Prostate Cancer vs Active Surveillance
This study will evaluate the safety and efficacy of a prostate cancer vaccine named Proscavax (Prostate-specific antigen(PSA) / Interleukin-2(IL-2) / Granulocyte-macrophage colony-stimulating factor(GM-CSF)) in patients with…
- Trial name
- NCT03579654
- Testing
- Proscavax
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- OncBioMune Pharmaceuticals
Prostate Cancer
A Study of MRI-guided High-dose Radiation Therapy in Prostate Cancer
One of the usual approaches to treating intermediate-risk prostate cancer is a type of radiation therapy called SBRT (stereotactic body radiation therapy).
- Trial name
- NCT04997018
- Testing
- Radiation Therapy
- Where
- 7 sites in United States
- Volunteers
- 91 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer of the PROSTATE
Multicentric Study Comparing Carcinological and Functional Results of Surgery
National multicentric prospective open study, comparing two current surgical methods: laparoscopic way versus open retropubic way among patients requiring a radical prostatectomy for a localised prostate cancer.
- Trial name
- PROPENLAP (NCT00502723)
- Testing
- Radical retropubic prostatectomy, Radical laparoscopy prostatectomy
- Where
- France
- Volunteers
- 1,440 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Advanced HR+/HER2- Breast Cancer, Advanced CCNE1-amplified Solid Tumors
Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors
Phase I: Characterize safety and tolerability of GVV858 as a single agent and in combination with fulvestrant or letrozole. Identify dose range for optimization/recommended dose for further clinical evaluation.
- Conditions
- Advanced HR+/HER2- Breast Cancer, Advanced CCNE1-amplified Solid Tumors, Metastatic Castration-resistant Prostate Cancer
- Trial name
- NCT07288359
- Testing
- GVV858, Fulvestrant, Letrozole
- Where
- 16 sites in United States, Canada and 9 more
- Volunteers
- 205 people
- Sponsor
- Novartis Pharmaceuticals
Prostate Cancer, Localized Carcinoma
Validation of the Stockholm3 Test for Detection of Prostate Cancer in the Swiss Population
The purpose of this study is to collect blood samples to investigate the prognostic performance of the STHLM3 test in a population of Swiss and German men suspected of harbouring prostate cancer based on a combination of elevated…
- Trial name
- NCT05294627
- Testing
- Stockholm3
- Where
- Switzerland
- Volunteers
- 380 people
- Sponsor
- University Hospital, Basel, Switzerland
Prostate Cancer
Real-life Study of Patients After 3-months of Leuprorelin 5mg Implant in Prostate Cancer
To improve the management of patients suffering from prostate cancer, Laboratoires BOUCHARA-RECORDATI wish to set up an observational study to document, in daily practice, and over a large population, the profile and clinical and…
- Trial name
- LEPTO (NCT03990194)
- Testing
- Leuprolide Acetate
- Sponsor
- RECORDATI GROUP
Prostate Cancer
Hormone Therapy With or Without Squalamine Lactate in Treating Patients Who Are Undergoing a Radical Prostatectomy for Locally Advanced Prostate Cancer
RATIONALE: Androgens can cause the growth of prostate cancer cells. Drugs, such as leuprolide and bicalutamide, may stop the adrenal glands from making androgens.
- Trial name
- NCT00244920
- Testing
- bicalutamide, leuprolide acetate, squalamine lactate
- Sponsor
- OHSU Knight Cancer Institute
Lymphoma, Prostate Cancer
AMG-479 in Treating Patients With Advanced Solid Tumors or Non-Hodgkin Lymphoma
RATIONALE: Monoclonal antibodies, such as AMG-479, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread.
- Conditions
- Lymphoma, Prostate Cancer, Sarcoma, Small Intestine Cancer
- Trial name
- NCT00562380
- Testing
- ganitumab, laboratory biomarker analysis, pharmacological study
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Amgen
Prostate Cancer
SRT Versus SRT+ADT in Prostate Cancer
To clarify the role of short-term Androgen deprivation therapy (ADT) in the context of intermediate unfavorable and a subclass of high-risk patients treated with prostate Stereotactic radiotherapy (SRT).
- Trial name
- SPA (NCT05019846)
- Testing
- Triptorelin Embonate, Bicalutamide 50 mg
- Where
- Italy
- Volunteers
- 310 people
- Sponsor
- Marco Lorenzo Bonu
Hormone-Resistant Prostate Cancer, Metastatic Prostatic Adenocarcinoma
Phenelzine Sulfate and Docetaxel in Treating Patients With Prostate Cancer With Progressive Disease After First-Line Therapy With Docetaxel
This phase II trial studies how well giving phenelzine sulfate together with docetaxel works in treating patients with prostate cancer that is growing, spreading, or getting worse after first-line therapy with docetaxel.
- Conditions
- Hormone-Resistant Prostate Cancer, Metastatic Prostatic Adenocarcinoma, Prostate Adenocarcinoma, Recurrent Prostate Carcinoma
- Trial name
- NCT01253642
- Testing
- Biopsy of Prostate, Docetaxel, Laboratory Biomarker Analysis
- Where
- 3 sites in United States
- Volunteers
- 11 people
- Sponsor
- OHSU Knight Cancer Institute
Prostate Cancer
Leuprolide, Bicalutamide, and Implant Radiation Therapy in Treating Patients With Locally Recurrent Prostate Cancer After External-Beam Radiation Therapy
RATIONALE: Androgens can cause the growth of prostate cancer cells. Antihormone therapy, such as leuprolide and bicalutamide, may lessen the amount of androgens made by the body.
- Trial name
- NCT00684905
- Testing
- bicalutamide, leuprolide acetate, adjuvant therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Prostate Cancer, Radiotherapy Side Effect
PROstate CAncer Radiotherapy - Bowel Quality of Life (PROCAR-BQ)
This is a prospective pilot study to evaluate the mean increase of bowel symptoms after pelvic radiotherapy (RT) in prostate cancer (PCa) patient using the validated \& newly translated EORTC-QLQ PRT20 module.
- Conditions
- Prostate Cancer, Radiotherapy Side Effect, Bowel Dysfunction, Quality of Life
- Trial name
- PROCAR-BQ (NCT05880446)
- Testing
- Bowel symptoms & QoL assessment
- Where
- Belgium
- Volunteers
- 41 people
- Sponsor
- Jules Bordet Institute
Prostatic Neoplasms
Safety, Biodistribution, Radiation Dosimetry and Pharmacokinetics Study of BAY88-8223 in Japanese Patients
This is an uncontrolled, open-label, non-randomized Phase I study to investigate safety, biodistribution, radiation dosimetry and pharmacokinetics of a single dose of BAY88-8223 in Japanese patients with castration-resistant…
- Trial name
- NCT01565746
- Testing
- Radium-223 dichloride (Xofigo, BAY88-8223)
- Where
- 3 sites in Japan
- Volunteers
- 19 people
- Sponsor
- Bayer
Prostate Cancer
Study Investigating the Long-Term Safety and Tolerability of Repeated Doses of Degarelix in Prostate Cancer Patients
To investigate the long-term safety and tolerability of repeated doses of degarelix to prostate cancer patients
- Trial name
- NCT00245466
- Testing
- Degarelix
- Volunteers
- 88 people
- Sponsor
- Ferring Pharmaceuticals
Prostate Cancer, Advanced Cancer
SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization
The investigators will study SPECT imaging of radiopharmaceutical therapies given as standard of care or as part of other compatible research protocols.
- Trial name
- (SEEtoTREAT) (NCT06389097)
- Testing
- Radium-223, 177Lu-DOTATATE, 177Lu-PSMA-617
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Neoplasms, Breast Neoplasms
Rehabilitation of Cancer Survivors in Denmark: The Effect of a Psychosocial Rehabilitation Course
This randomized study evaluates the effect of a multi-focused, psychosocial 6-day residential rehabilitation course at a Danish rehabilitation centre for cancer survivors.
- Conditions
- Neoplasms, Breast Neoplasms, Colorectal Neoplasms, Prostatic Neoplasms
- Trial name
- NCT01086683
- Testing
- Psychosocial rehabilitation course
- Where
- Denmark
- Volunteers
- 513 people
- Sponsor
- Danish Cancer Society
Prostate Cancer
A Phase 2 Study to Evaluate Safety and Efficacy of Abiraterone in Participants With Prostate Cancer Who Have Received Docetaxel
The purpose of this study is to investigate the safety and efficacy of abiraterone in participants with metastatic castration-resistant prostate cancer (mCRPC) who have received docetaxel-based chemotherapy (treatment of disease…
- Trial name
- NCT01795703
- Testing
- Abiraterone, Prednisolone
- Where
- 18 sites in Japan
- Volunteers
- 47 people
- Sponsor
- Janssen Research & Development, LLC
Prostate Cancer
Soccer Intervention in Prostate Cancer Survivors
This study seeks to directly test the implementation feasibility of a soccer-based and lifestyle education intervention to determine the effects on bone health, body composition, mental health, functional and cardiometabolic…
- Trial name
- NCT04144127
- Testing
- Soccer
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Emory University
Cancer Related Fatigue
Body Mind Training Project
Aim 1: Assess the feasibility, safety and efficacy of a Qigong intervention in elderly prostate cancer survivors. Describe participation, retention, and adherence rates and assess reasons for participation, attrition, and…
- Trial name
- NCT01564394
- Testing
- Qigong, Non-aerobic stretching
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Utah
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