Clinical trials: Carcinomatosis, Peritoneal
Cancer, Peritoneal Carcinosis
Development of a Clinical and Biological Database in Peritoneal Carcinosis (BCB CARCINOSE)
The creation of a prospective clinical-biological base dedicated to peritoneal carcinosis must therefore be able to serve as a support for this essential search for transfer.
- Trial name
- BCB (NCT04221464)
- Testing
- biological collection, Tissues collections
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Peritoneal Carcinomatosis, Gastric Cancer
Intraoperative ICG Fluorescence Imaging for Peritoneal Carcinomatosis Detection
Background. Peritoneal carcinomatosis is a frequent and deadly localization of gastric cancer. Available imaging techniques have a low accuracy in detecting small peritoneal nodules, and direct laparoscopic visualization may fail…
- Trial name
- NCT04352894
- Testing
- Fluorescence guided peritoneal exploration
- Volunteers
- 120 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Colorectal Cancer, Peritoneal Carcinomatosis
Near-Infrared Imaging of Peritoneal Carcinomatosis From Colorectal Cancer
The purpose of this study is to determine if Near-Infrared fluorescence imaging is an effective approach to detect the colorectal tumoral tissues and peritoneal implants in colorectal cancer patients.
- Trial name
- OC-AP-ICG-IV (NCT02032485)
- Testing
- Indocyanine Green
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Jules Bordet Institute
Peritoneal Carcinomatosis
Second Line Oxaliplatin Based Chemotherapy Alone Versus Oxaliplatin Based PIPAC and Chemotherapy in Colorectal Peritoneal Carcinomatosis : A Phase II Randomize Mutli-centric Study
Colorectal cancer is the third most common cancer in men and second in women. It represent 345'346 new cases per year in Europe and 134'349 in the United States of America.
- Trial name
- OPAC (NCT04734691)
- Testing
- PIPAC
- Volunteers
- 50 people
- Sponsor
- Sleiman Marwan-Julien
Gastric Cancer, Peritoneal Carcinomatosis
Complete Cytoreduction Followed by IP and Systemic Chemotherapies for Gastric Cancer With Peritoneal Carcinomatosis
Background: Approximately 15% of gastric adenocarcinoma patients presents with peritoneal carcinomatosis (PC) at the first encounter and is regarded as an unresectable and end-stage disease.
- Trial name
- CRS-IP (NCT04547725)
- Testing
- CRS followed by IP and systemic chemotherapies
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- National Taiwan University Hospital
Ventral Hernias, Cytoreductive Surgery
Ventral Hernias Following Cytoreductive Surgery : Incidence, Risk Factors and Surgical Management.
Cytoreductive surgery (CRS), with or without hyperthermic intraperitoneal chemotherapy (HIPEC), is currently the standard treatment for advanced peritoneal tumors, including pseudomyxoma peritonei (PMP), colorectal, and ovarian…
- Trial name
- NCT07451483
- Where
- Belgium
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute
Peritoneal Surface Malignancy, Postoperative Adhesion
SurgiPerito Trial: High-Purity Type-I Collagen for Peritoneal Reconstruction After Cytoreductive Surgery
This dual-centre, randomized controlled trial evaluates the safety and efficacy of high-purity Type-I collagen-based biomaterial, as a peritoneal substitute following peritonectomy in patients undergoing cytoreductive surgery…
- Conditions
- Peritoneal Surface Malignancy, Postoperative Adhesion, Bowel Obstruction, Wound Complications
- Trial name
- NCT07241091
- Testing
- High-Purity Type-I Collagen Scaffold, Standard Peritonectomy Closure
- Where
- 2 sites in India
- Volunteers
- 60 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Cancer
Interleukin-12 in Treating Patients With Refractory Advanced-Stage Ovarian Cancer or Abdominal Cancer
Phase I trial to study the effectiveness of interleukin-12 in treating patients with refractory ovarian or abdominal cancers. Interleukin-12 may kill tumor cells by stopping blood flow to the tumor and by stimulating a persons's…
- Trial name
- NCT00003439
- Testing
- recombinant interleukin-12
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- National Cancer Institute (NCI)
Peritoneal Carcinomatosis
Study in Patients With Peritoneal Carcinomatosis From CEA Overexpressing Digestive Cancer
The digestive cancer is the second cause of death worldwide. The presence of peritoneal carcinomatosis is common in the evolution of this type of cancer, as well as increased levels of ACE.
- Trial name
- FLUOCAR-1 (NCT02784028)
- Testing
- SGM-101
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Peritoneal Carcinomatosis
Preoperative Inflammatory Markers Predict Postoperative Complications After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Colorectal Carcinomatosis
A retrospective study of a single-center prospective database of patients who underwent curative CRS-HIPEC for peritoneal carcinomatosis (PC) of colo-rectal cancer (CRC), between September 2012 and July 2023 at Reims…
- Trial name
- NCT06318793
- Where
- France
- Volunteers
- 166 people
- Sponsor
- CHU de Reims
Peritoneal Carcinomatosis
Role of Intraperitoneal Intraoperative Chemotherapy With Paclitaxel in the Surgical Treatment of Peritoneal Carcinomatosis From Ovarian Cancer. Hyperthermia Versus Normothermia
A randomized controlled single-blind clinical trial was performed, in 32 patients diagnosed with peritoneal carcinomatosis from epithelial ovarian cancer, who underwent radical surgery-peritonectomy, achieving an optimal R0-R1…
- Trial name
- NCT02739698
- Testing
- Paclitaxel, Radical surgery-peritonectomy
- Volunteers
- 32 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Malignant Neoplasm of Pancreas Metastatic to Peritoneal Surface, Malignant Peritoneal Mesothelioma
αDC1 Vaccine + Chemokine Modulatory Regimen (CKM) as Adjuvant Treatment of Peritoneal Surface Malignancies
This trial is to determine the safest dose of a triple combination (chemokine modulatory regimen or CKM) of celecoxib, interferon alfa (IFN), and rintatolimod that can be given with a DC vaccine as treatment of peritoneal surface…
- Conditions
- Malignant Neoplasm of Pancreas Metastatic to Peritoneal Surface, Malignant Peritoneal Mesothelioma, Peritoneal Carcinomatosis
- Trial name
- NCT02151448
- Testing
- DC vaccine, Celecoxib, Interferon Alfa-2b
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- David Bartlett
Colorectal Cancer
Assessing Safety of NIPOX in Peritoneal Carcinomatosis of CRC
This study determine the maximal tolerate dose
- Trial name
- NIPOX (NCT03253133)
- Testing
- Oxaliplatin, LV5FU or Folfiri, Oxycodone
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Peritoneal Cancer
Oxaliplatin and Paclitaxel Plus Bevacizumab in Advanced Peritoneal Carcinomatosis
The goal of this clinical research is to learn acceptable dosages of paclitaxel, oxaliplatin, and Avastin (bevacizumab) that can be given in combination to patients with advanced peritoneal carcinomatosis.
- Trial name
- NCT00491855
- Testing
- Bevacizumab, Oxaliplatin, Paclitaxel
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
Ascites, Peritoneal Carcinomatosis
Comparison of "Roll-over' Technique With Standard Abdominal Paracentesis in Suspected Peritoneal Carcinomatosis
The study will be a randomized trial that will compare two techniques of abdominal paracentesis in patients with suspected peritoneal carcinomatosis.
- Conditions
- Ascites, Peritoneal Carcinomatosis, Peritoneum Neoplasm, Tuberculous Peritonitis
- Trial name
- ROLLON (NCT04232384)
- Testing
- Standard Paracentesis, Roll Over Paracentesis
- Where
- India
- Volunteers
- 71 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Peritoneal Neoplasms, Stomach Neoplasms
Phase I Study of Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Escalating Dose I.P. Platinum for Gastrointestinal Peritoneal Carcinomatosis
Patients with gastric adenocarcinoma are most frequently diagnosed at an advanced stage. The disease has a marked propensity for loco-regional spread and will be the sole or major site of disease in up to 80% of patients.
- Trial name
- NCT00001332
- Testing
- CHPP with cisplatin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute (NCI)
Peritoneal Carcinomatosis
Longitudinal Study of CRS/HIPEC for Peritoneal Carcinomatoses
Longitudinal Study of the Effect of Cytoreductive Surgery and HIPEC in Patients With Peritoneal Carcinomatoses
- Trial name
- CRS/HIPEC (NCT04108936)
- Where
- 2 sites in Germany
- Volunteers
- 250 people
- Sponsor
- University of Regensburg
Gastric Cancer
Preventive Use of PIPAC in Locally Advanced Gastric Cancer.
Gastric cancer is the fifth most common cancer worldwide and the third leading cause of cancer-related mortality. In patients with locally advanced gastric cancer, multimodal treatment strategies, including perioperative…
- Trial name
- NCT06784765
- Testing
- Intervention Group, Control Group
- Where
- Kazakhstan
- Volunteers
- 160 people
- Sponsor
- National Research Oncology and Transplantology Center, Kazakhstan
Carcinoma
The Role of Pre-operative and Post-operative Circulating Tumor Cells in Gastric Cancer.
In resectable gastric cancer participants who received curative surgery, to early and more accurately detect peritoneal carcinomatosis or occult metastasis is important.
- Trial name
- NCT05752357
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
Peritoneal Carcinomatosis
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) : Predictive Marker and Mechanism
Peritoneal carcinomatosis (PC) is the stage III of the FIGO ovarian cancer staging. It corresponds to an advanced stage with a relative 5 year survival rate of 52%.
- Trial name
- NCT02803515
- Testing
- peripheral venous blood samples
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Centre Hospitalier Universitaire de Nice