Clinical trials: Cardiac
Blood Pressure, Heart Rate Variability
The Cardiovascular Benefits of Reducing Personal Exposure to Air Pollution
Exposure to air pollution is an important risk factor for cardiovascular morbidity and mortality, and is associated with increased blood pressure, reduced heart rate variability, endothelial dysfunction and myocardial ischaemia.
- Trial name
- NCT00809432
- Testing
- Face mask (Dust Respirator), No Face mask
- Where
- China
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Coronary Artery Disease, Coronary Atheroscleroses
Screening Coronary Artery Disease Using artiFicial intelligencE in Non-contrast Computed Tomography
This project aims to improve direct patient care by reducing the risks of futile exposure to ionizing radiation and iodinated contrast in patients referred for coronary computed tomography angiography
- Trial name
- SAFE-CT (NCT06438393)
- Testing
- CT coronary angiography and non-contrast CT
- Where
- Portugal
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Fever, COPD
The Application of a Wireless Sensor Technology for Vital Statistics in CHILDREN AND ADULTS
The primary outcome for this project will be the development of a small, non-invasive wireless sensor that is linked to a conventional computer that can be used in health care for monitoring of acute and chronic health problems.
- Conditions
- Fever, COPD, Obesity, Congenital Heart Disease
- Trial name
- NCT01845506
- Testing
- Cardiorespiratory monitor, Wireless pressure sensor
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chronic Heart Failure
A Study to Evaluate the Safety, Pharmacokinetics of AD-118 and AD-1181 in Healthy Adult Subjects
A Study to Evaluate the Safety and Pharmacokinetics of AD-118 and AD-1181 Under Fasted Conditions in Healthy Adult Subjects
- Trial name
- NCT07717749
- Testing
- AD-118, AD-1181
- Where
- South Korea
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Addpharma Inc.
Atrial Fibrillation (AF), Cardiac Arrhythmias
Comparison of 7-Day ECG Patches
This prospective, randomized, multi-arm study evaluates the usability and performance of commercially available CE-certified 7-day ECG patches in an outpatient setting.
- Trial name
- NCT07564349
- Testing
- Smartcardia 7L Patch, ECG247, HeartX Recorder
- Where
- Austria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Heart Failure
Point of Care Artificial Intelligence Tool for Heart Failure Diagnosis
Abbreviations/acronyms: DUO-EF = prediction of ejection fraction (EF) using the Eko-DUO digital stethoscope algorithm HF = heart failure HFrEF = heart failure with reduced ejection fraction COVID-19 = coronavirus disease 2019 Eko…
- Trial name
- DUO-EF-19 (NCT04601415)
- Testing
- ECG from handheld device
- Where
- United Kingdom
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Atrial Fibrillation, Heart Failure, Diastolic
The Effect of Different Low-Level Tragus Stimulation Parameters On Autonomic Nervous System Function
Low level transcutaneous vagus nerve stimulation (LLTS) involves delivery of electrical impulses transcutaneously at the auricular branch of vagus nerve and it has been shown to have anti-inflammatory and anti-arrhythmic effects.
- Trial name
- LLT-SPANS (NCT04682704)
- Testing
- Parasym
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Acute Decompensated Heart Failure (ADHF)
Comparison of the Effectiveness of Different Diuretic Therapies in the Management of Acute Heart Failure
Acute decompensated heart failure (ADHF) is a clinical syndrome associated with high morbidity and mortality rates. Current guidelines emphasize the importance of oxygenation and diuresis in the management of ADHF.
- Trial name
- NCT07464249
- Testing
- Furosemide Bolus, Furosemide Continuous İnfusion
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Inflammation, Death, Sudden, Cardiac
The Effects of Enzymes and Flavonoids on Inflammation and Coagulation After Marathon
The aim of the present study is to investigate changes in inflammatory status and incidence of infection after extreme aerobic physical stress (participation in a marathon).
- Conditions
- Inflammation, Death, Sudden, Cardiac, Death, Heart Diseases
- Trial name
- Enzy-MagIC (NCT01916408)
- Testing
- Wobenzym plus, PL 1
- Where
- Germany
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Heart Failure, Acute Kidney Injury
Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome
The overall objective of this study is to determine whether the addition of SGLT2 inhibitors to usual care in hospitalized patients with heart failure associated acute kidney injury is safe and efficacious.
- Trial name
- NCT07273838
- Testing
- Dapagliflozin 10mg Tab
- Where
- 2 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Yale University
Congenital Heart Disease, Single Ventricle
Cardiovascular, Pulmonary and Skeletal Muscle Evaluation Postoperative in Fontan Patients: Effects of Exercise Training
Introduction: The Fontan operation is the surgical treatment in most patients with either anatomic or functional single ventricles.
- Conditions
- Congenital Heart Disease, Single Ventricle, Univentricular Heart
- Trial name
- NCT02283255
- Testing
- Aerobic Exercise Training, Inspiratory Muscle Training, No Exercise Training
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cardiovascular Disease, Preeclampsia
Heart Health 4 Moms Trial to Reduce CVD Risk After Preeclampsia
This study will compare two arms in a randomized clinical trial of cardiovascular risk prevention in women with a history of preeclampsia.
- Conditions
- Cardiovascular Disease, Preeclampsia, Hypertension, Post-partum Weight Retention
- Trial name
- HH4M (NCT02147626)
- Testing
- Web-based educational and motivational modules, Information and Screening Group
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Alzheimer Disease
Effects of Heart Rate Oscillations During Meditation on Plasma Biomarkers of Alzheimer's Disease
In the current study, we will examine how two types of concentration meditation practices affect plasma biomarkers of Alzheimer's Disease (AD).
- Trial name
- NCT06210035
- Testing
- Belly-focus meditation, Belly-focus meditation with slow breathing
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cardiovascular Disease, Healthy
Technical Evaluation of Cardiovascular Magnetic Resonance Imaging and Spectroscopy
Magnetic resonance imaging (MRI) and spectroscopy are diagnostic tools that create high quality images of the human body without the use of X-ray (radiation).
- Trial name
- NCT00001874
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Sudden Cardiac Death, Implantable Defibrillator User
Implantable Cardioverter Defibrillators - Improving Risk Stratification
Worldwide three million people a year die from sudden cardiac death (SCD). In most cases there is no warning and the heart is stopped by a sudden arrhythmia.
- Conditions
- Sudden Cardiac Death, Implantable Defibrillator User, Myocardial Infarction, Arrhythmias, Cardiac
- Trial name
- ICD-IRS (NCT01944514)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Arrhythmias, Cardiac
Effect of Monitoring System Design on Response Time to Cardiac Arrhythmias
To increase the potential for timely detection and treatment of cardiac events, hospitals have implemented a number of different cardio-respiratory monitoring methods for at-risk patients.
- Trial name
- NCT02466633
- Testing
- In-hospital cardiac monitoring method
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Duke University
Severe Cardiomyopathy, Angina, Unstable
Hemodynamics During the Soccer Championship 2012
The purpose of this study is to determine in soccer fans whether and to which extend positive or negative emotions during the European soccer Championship affects Central Hemodynamics, Arterial Stiffness, Heartrate and…
- Conditions
- Severe Cardiomyopathy, Angina, Unstable, Myocardial Infarction, Angina, Stable
- Trial name
- NCT01617863
- Where
- 4 sites in Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Coronary Artery Disease, Coronary Disease
The Effect of Hand Reflexology on Anxiety and Vital Signs With Angiography
This study was planned to determine the effect of hand reflexology on anxiety and vital signs in patients undergoing coronary angiography.
- Trial name
- NCT04956055
- Testing
- Reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Atrial Fibrillation
Imaging-based, Non-invasive Diagnosis of Persistent Atrial Fibrillation
The main objective of the present project is to develop an imaging-based tool to determine the origin and cause of persistent atrial fibrillation (AF).
- Trial name
- imATFIB (NCT03584126)
- Testing
- Electrocardiography, ecocardiography and MRI.
- Where
- Romania
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- County Clinical Emergency Hospital Cluj-Napoca
Takotsubo Cardiomyopathy
Life-style Interventions for Modulating the Brain Phenotype of Takotsubo Cardiomyopathy
Takotsubo cardiomyopathy presents like a heart attack and is typically triggered by intense emotional or physical stress. Recovery of this condition varies and many patients continue to suffer from symptoms such as fatigue and…
- Trial name
- BREAKOUT (NCT05530135)
- Testing
- Exercise program, Cognitive behavioural therapy, Standard clinical care
- Where
- United Kingdom
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
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