Clinical trials: Cardiac
Heart Diseases, Lung Diseases
The Usefulness of Patients Receiving Their Own Letter After an Outpatient Attendance
As part of the NHS plan it has been proposed to extend some consultants' usual practices and to send all patients copies of the letters sent to their general practitioners (GPs) following outpatient consultations.
- Trial name
- NCT00129636
- Testing
- Additional specific letter written to patient
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Bradyarrhythmia
Identify the Genes Polymorphisms Related to Non-familial Bradyarrhythmia
Bradyarrhythmia, including sinus node dysfunction and atrioventricular block, is a major cause necessitating pacemaker implantation.
- Trial name
- NCT01310907
- Where
- 2 sites in Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Rest Gated Myocardial Perfusion Imaging in Heart Failure
18F-MFBG Cardiac Imaging for Heart Failure Administration
The clinical feasibility of 18F-FMBG cardiac PET imaging will be observed in sympathetic nervous system activity in patients with heart failure, predicted cardiac events, guided ICD implantation, and evaluated therapy efficiency.
- Trial name
- NCT06149195
- Testing
- Standard medical care for heart failure
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sichuan Provincial People's Hospital
Acute Kidney Injury, Heart Valve Diseases
Correlation of Brain and Thenar Muscle Oximetry During Cardiac Surgery With Parameters of Acute Kidney Injury
Identification of risk factors of acute kidney injury (AKI). It is hypothesized that there might be a correlation between brain oximetry, tissue saturation of thenar muscle and marker of AKI in blood - neutrophil…
- Trial name
- NCT02979275
- Testing
- Open heart surgery on cardiopulmonary bypass.
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Heart Murmurs, Wheezing
Validate the Efficacy and the Safety of the Keikku Electronic Stethoscope for Its Indication and Intended Purpose, Under the Intended Conditions of Use.
This study is testing a digital stethoscope called the Keikku electronic stethoscope. Doctors use stethoscopes to listen to the heart, and this new device records heart sounds using a smartphone app.
- Trial name
- KCI-1 (NCT07044128)
- Testing
- Digital stethoscope using MEMS sensor and mobile application for cardiac auscultation
- Where
- Peru
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Lapsi Health Holding B.V.
Cardiac Surgical Procedures
Opioid Sparing Pain Management Strategy
The purpose of this research study is to compare the amount of morphine milligram equivalents consumed post operatively until discharge between the control cohort and intervention cohort.
- Trial name
- NCT04269109
- Testing
- Multi-modal Opioid Sparing Pain Management Protocol
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Upstate
Thyroid, Thyroidectomy
Post Thyroidectomy Myocardial Function
Protocol Synopsis Protocol title: Post thyroidectomy myocardial function Purpose: Evaluation of the effects of total thyroidectomy on myocardial function Design: Prospective, single-center, cohort study Patient Population: Male…
- Conditions
- Thyroid, Thyroidectomy, Myocardial Function
- Trial name
- TECH (NCT03060499)
- Where
- Greece
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Auscultation of Heart, Simulation Based Learning
The Effect of Simulation on Cardiac Auscultation Competence
This randomized controlled study aims to determine the effect of simulation on the cardiac auscultation competence of nursing students.
- Conditions
- Auscultation of Heart, Simulation Based Learning, Psychoacoustics
- Trial name
- NCT06689475
- Testing
- Psychoacoustic approach, Simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Gazi University
Heart Failure, Ageing
Leipzig Exercise Intervention in Chronic Heart Failure and Aging
In both ageing and heart failure progressive exercise intolerance is observed. The Leipzig Exercise Intervention in Chronic heart failure and Aging (LEICA) study aims to investigate how aerobic short-term training interventions…
- Trial name
- LEICA (NCT00176319)
- Testing
- Aerobic endurance exercise training (ergometer)
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Periodontitis, Cardiac Electrophysiology
Effects of Periodontitis on Heart Rate Variability
Periodontitis is a chronic inflammatory disease associated with systemic inflammatory burden and possible alterations in autonomic nervous system regulation.
- Trial name
- NCT07735312
- Testing
- Non-surgical periodontal therapy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cardiac Arrest, Hyperventilation
Investigation of a Novel Turbine-driven Ventilator for Use in Cardiopulmonary Resuscitation
The objective of this study is to determine whether healthcare professionals trained in CPR can deliver more effective ventilations during CPR using the Handivent, a novel turbine-driven ventilator as compared to bag-valve-mask…
- Trial name
- NCT02743299
- Testing
- Handivent Ventilator
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Utah
Cardiovascular Disease
Implementation of Practice Standards for ECG Monitoring
The purpose of this study is to test the effect of implementing new practice standards for electrocardiographic (ECG) monitoring on nurses' knowledge and skills, quality of care, and patient outcomes.
- Trial name
- PULSE (NCT01269736)
- Testing
- Education
- Where
- 16 sites in United States, Canada and 1 more
- Volunteers
- 92,057 people, healthy volunteers welcome
- Sponsor
- Yale University
Psoriasis
Effects of Treatment With Biological Agents on Vascular and Cardiac Function in Psoriasis
Psoriasis has been associated with an increasing risk for atherosclerosis. The investigators investigated whether surrogate markers of subclinical atherosclerosis, vascular dysfunction and myocardial dysfunction are impaired in…
- Trial name
- NCT02144857
- Testing
- etanercept, ustekinumab, cyclosporine
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Athens
Healthy, Physical Activity
Virtual Reality Exergaming on Heart Rate, Perceived Exertion, and Technology Acceptance in Healthy Individuals
This pilot cohort study aimed to investigate the immediate impact of Virtual Reality (VR) exergaming on heart rate (HR), rate of perceived exertion (RPE), and technology acceptance using the Unified Theory of Acceptance and Use…
- Conditions
- Healthy, Physical Activity, Virtual Reality, Exergame
- Trial name
- NCT06411119
- Testing
- Meta Oculus Quest 2™ Virtual Reality Exergaming
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Teesside University
Parent-Child Relations, Development, Infant
Hands and Hearts Together
Growing evidence demonstrates that secure attachment in childhood predicts children's healthy social, biological, and behavioral functioning, whereas insecure attachment predicts behavior problems and physiological dysregulation…
- Conditions
- Parent-Child Relations, Development, Infant, Parenting, Development, Child
- Trial name
- NCT05834907
- Testing
- Circle of Security Parenting, Little Talks
- Where
- 2 sites in United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Patients With Cardiovascular Disease, Healthy Participants
OCTA in Cardiovascular Disease and Healthy Controls
This prospective clinical study will involve the non-invasive assessment of retinal vessels using OCTA (Cirrus OCT 6000 AngioPlex) and scanning laser Doppler flowmetry (SLDF) in patients with cardiovascular disease and healthy…
- Trial name
- NCT07359664
- Testing
- Retinal vascular assessment using OCTA and SLDF
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Infectious Endocarditis
Evaluation of an Antibiotic Regimen Pharmacokinetic Applicable to Enterococcus Faecalis Infective Endocarditis
The clinical trial is designed as a phase II, crossover clinical trial. It will be carried out in healthy volunteers, who will receive two different antibiotic regimen based on ceftriaxone.
- Trial name
- NCT03681431
- Testing
- Ceftriaxone 4g/ 24h, Ceftriaxone 2g/ 12h
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Atrial Fibrillation, Acute Coronary Syndrome
Antithrombotic Triple Therapy in Humans
Background:The acute coronary syndrome (ACS) is a complication of coronary artery disease (CAD) and associated with increased mortality.
- Trial name
- NCT01812200
- Testing
- Dabigatran, Ticagrelor, ASA, Rivaroxaban, Ticagrelor, ASA, Phenprocoumon, Ticagrelor, ASA
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Healthy
Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing
The purpose of this research is to understand how to apply cardiac magnetic resonance imaging (CMR) to women with small artery heart disease by looking at the CMRs of women without heart disease.
- Trial name
- NCT00573339
- Testing
- Cardiac MRI
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Heart Failure
A Study Designed to Assess the Mass Balance Recovery, Absorption, Metabolism, Excretion of [14C]AZD5462 and the Absolute Bioavailability of AZD5462
A study to investigate how the body breaks down and gets rid of the test medicine, AZD5462. To help investigate this, the test medicine is radiolabelled, which means that the test medicine has a radioactive component (carbon-14)…
- Trial name
- NCT06989983
- Testing
- AZD5462 film-coated tablet, [14C]AZD5462 Solution for Infusion, [14C]AZD5462 Oral Solution
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
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