Clinical trials: Cardiac Allograft Vasculopathy
Heart Transplant Recipients
Autonomic Cardiovascular Control After Heart Transplantation
The purpose of this prospective study is to investigate denervation (ie. surgical cutting of autonomic nerves) and re-innervation (ie. growth of autonomic nerves) in heart transplant recipients. More specifically, we focus on: 1.
- Trial name
- AccHeart (NCT01759966)
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cardiac Allograft Vasculopathy
A P2X7R Single Nucleotide Mutation Promotes Chronic Allograft Vasculopathy
Heart transplantation (HT) is a lifesaving procedure for patients with end-stage heart failure and provides a better survival and quality of life if compared to medical treatment.
- Trial name
- NCT02082821
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Heart Transplant Recipients
The GRAFT Study: Evaluation of Graft Function, Rejection and Cardiac Allograft Vasculopathy in First Heart Transplant Recipients.
Objective: To assess the relationship between coronary allograft vasculopathy (CAV) and graft function, and to evaluate non-invasive methods for CAV diagnosis.
- Trial name
- NCT02077764
- Testing
- OCT and coronary angiography, Right heart cat., PET
- Where
- Denmark
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital Skejby
Cardiac Allograft Vasculopathy
Noninvasive Evaluation of Cardiac Allograft Vasculopathy
Abnormal peripheral endothelial function and alterations in circulating biomarkers that are associated with endothelial activation and inflammation correlate with angiographic evidence of cardiac allograft vasculopathy, defined…
- Trial name
- CAVII (NCT01305382)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota