Clinical trials: Cardiac Anesthesia
Low Cardiac Output
Comparative Study of Haemodynamic Changes After Spinal Anaesthesia in Non-obese and Pregnant Women
Obesity has become one of the most common risk factors in obstetric practice with serious anaesthetic implications. Obese pregnants have limited physiological reserves and cardiovascular co- morbidities when compared to non-obese…
- Trial name
- NCT02599376
- Testing
- LiDCOrapid
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Autonomic Nervous System, Nerve Block
Heart Rate Variability and Electroencephalography Analysis in Laparoscopic Surgery With or Without Transversus Abdominis Plane Block
Heart rate variability(HRV) and electroencephalography(EEG) has been used widely in anesthetic practice nowadays. One of the most dominant applications is the nociception-analgesia balance.
- Conditions
- Autonomic Nervous System, Nerve Block, Laparoscopy, Anesthesia and Analgesia
- Trial name
- NCT04539080
- Testing
- transversus abdominis plane block
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
MYOCARD INFARCTUS, Non Cardiac Surgery
Myocardial Injury After Noncardiac Surgery (MINS) in Lumbar Surgery Patients
The aim of this study is to evaluate the incidence of myocardial injury after noncardiac surgery (MINS) in patients undergoing lumbar surgery, and to investigate the associated risk factors.
- Conditions
- MYOCARD INFARCTUS, Non Cardiac Surgery, Lumbar Surgery, Anesthesia
- Trial name
- NCT07081009
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Stress, Stress and Burnout
Deep Relaxation Using Virtual Reality Intervention Before Surgery for Healthcare Professionals Working in the Operating Room
The goal of this clinical trials is to primary learn if deep relaxation using Virtual Reality (VR) compared to a low stimulus environment can lower perceived and measured stress in healthcare professionals working in the…
- Conditions
- Stress, Stress and Burnout, Stress Biomarkers
- Trial name
- DEEP_VR (NCT07470697)
- Testing
- Virtual Reality intervention, Low Stimulus Environment
- Where
- 2 sites in Denmark, Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Hypotension, Hypertension
Norepinephrine ED90 Bolus After Spinal Anesthesia in Cesarean Section
The investigators are aiming to determine what is the effective intravenous dose required of an initial bolus of norepinephrine prior to a maintenance infusion to prevent a 20% decrease in maternal blood pressure from baseline…
- Conditions
- Hypotension, Hypertension, Nausea, Pain
- Trial name
- NCT06574555
- Testing
- Norepinephrine
- Where
- Chile
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Pain, Anxiety
The Use of Music for Pain and Anxiety Control During Abortion
Most first trimester abortions are performed under local anesthesia using either manual or electric vacuum suction aspiration. The majority of women undergoing these procedures experience some amount of pain and anxiety.
- Trial name
- NCT01013363
- Testing
- iPod Nano digital music player
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Columbia University
Postoperative Pain
Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management
To evaluate the efficacy of bilateral continuous erector spinae blocks (BESB) for postoperative analgesia in children and adolescents undergoing cardiac surgical procedures via sternotomy in the Early Recovery After Surgery…
- Trial name
- NCT04567407
- Testing
- Bilateral erector spinae blocks using ropivacaine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Coronary Artery Disease, Anesthesia
Influence of Oxygen on Perioperative Outcome in Patients Undergoing General Anaesthesia for Elective Non-cardiac Surgery
The purpose of this study is to investigate the impact of supraphysiologic oxygen (hyperoxia) on myocardial function in anaesthetized patients undergoing non-cardiac vascular surgery.
- Trial name
- Promise-O2 (NCT04808401)
- Testing
- Oxygen
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pregnancy, Cesarean Delivery
Transthoracic Echocardiographic Monitoring of Cardiac Output Effects of Colloid Preload and Crystalloid Coload During Cesarean Delivery Under Spinal Anesthesia
Transthoracic echocardiography (TTE) has been introduced in anesthesia and intensive care practice to assess the volume status and predict fluid responsiveness, with a few studies performed on pregnant women (5).
- Conditions
- Pregnancy, Cesarean Delivery, Spinal Anesthesia Induced Hypotension, Cardiac Output Measurement
- Trial name
- NCT06654687
- Testing
- Transthoracic Echocardiography, Ringer lactate 1000 ml, Albumin
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Sameh Fathy
Coronary Artery Disease, Cardiometabolic Risk Factors
Impact of New Anthropometric Indices on Outcomes After Cardiac Surgery
Obesity is associated with a number of risk factors for cardiovascular disease. Body mass index (BMI) is the most commonly recommended and used anthropometric measure to classify general obesity in clinical and epidemiological…
- Conditions
- Coronary Artery Disease, Cardiometabolic Risk Factors, Cardiac Anesthesia, Cardiac Surgery
- Trial name
- NCT05403294
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Education, Medical, Critical Care Ultrasonography
Focused Cardiac and Lung Ultrasound in Anesthesia/Critical Care - The Role of Self-directed Simulation-assisted Training Compared to a Traditional Supervised Approach
The purpose of this study is to determine whether a self-directed and simulation-based lung ultrasound (LUS) and focused cardiac ultrasound (FCU) curriculum is efficacious on anesthesia trainees' image acquisition skills and…
- Trial name
- NCT01972698
- Testing
- Self-directed and simulation-assisted training, Traditional apprenticeship training
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Arrythmia
Assessment of Adverse Cardiac Events Using Local Anesthesia With Adrenaline
The use of vasopressor supplement materials to local anesthetics is commonly used in procedures in various fields of dentistry, ENT (ear, nose, and throat), Plastic Surgery, Hand surgery and gastroenterology.
- Trial name
- NCT02738567
- Testing
- patients undergoing surgery or medical procedure
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Postoperative Pain
Comparison of Interpectoral+Serratus Anterior Block With Erector Spinae Block in Minimally Invasive Cardiac Surgery
Adequate pain management after minimally invasive cardiac surgery is essential for early ambulation and patient satisfaction. However, an incision similar to thoracotomy surgery is made by entering between the ribs, and a…
- Trial name
- NCT05743231
- Testing
- interpectoral area block + serratus anterior area block group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Pain, Anxiety
The Effect of Cold Spray Applied Before Local Anaesthesia
Coronary angiography is a reliable and valid method used in the diagnosis of Coronary Artery Disease (CAD). Coronary angiography is defined as the process of obtaining cineangiographic images by administering radio-opaque…
- Conditions
- Pain, Anxiety, Coronary Artery Disease
- Trial name
- EffectofCold (NCT06035237)
- Testing
- Cold Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ozkan Sir
Pediatric ALL, Cardiac Complication
Femoral Arterial Cannulation in Pediatrics
The goal of this clinical trial] is to evaluate the efficacy and safety of the ultrasound-guided "Modified Dynamic Needle Tip Positioning Short-Axis, Out-Of-Plane" (MDNTP-SAOP) technique compared to the "Conventional, Short-Axis…
- Conditions
- Pediatric ALL, Cardiac Complication, Anesthesia
- Trial name
- NCT07059624
- Testing
- "Modified Dynamic Needle Tip Positioning, Short-Axis, Out-Of-Plane" (MDNTP-SAOP), "Conventional, Short-Axis, Out-Of-Plane" (C-SAOP)
- Where
- Lebanon
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Geriatric, General Anesthesia Induced Hypotension
What Causes Low Blood Pressure After Anesthesia in Older Adults Having Non-Heart Surgery ?
The purpose of this study is to identify risk factors contributing to post-induction hypotension in geriatric patients undergoing elective non-cardiac surgery under general anesthesia at Dr.
- Conditions
- Geriatric, General Anesthesia Induced Hypotension, Elective Surgery, Hypotension
- Trial name
- GERIHYPO (NCT07019805)
- Testing
- Standard General Anesthesia Induction Using Propofol, Fentanyl and Midazolam, Blood Pressure Continous Monitoring, syrnge pump for the anesthesia agent, and vasoconstrictor drug
- Where
- Indonesia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Cardiac Arrythmias
Carbetocin on Myocardial Repolarization Dynamics in Obstetrics Study
Relationship between carbetocin dose on transmural dispersion of repolarization (TDR).
- Trial name
- CaRDIO (NCT03716076)
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Tachycardia, Hypertension
To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU.
The goal of this clinical trial is to to observe the haemodynamic parameters including Heart Rate Blood pressure Respiratory rate and Oxygen Saturation with or without giving reversal agent on extubation in patients receiving…
- Conditions
- Tachycardia, Hypertension, Hypoxia, Hyperventilation
- Trial name
- NCT07097441
- Testing
- neostigmine (reversal agent)
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Tachycardia
Incident and Extent of Pulse Alteration During Local Anesthesia in Children
Incident and extent of pulse alteration during administration of various modes of local anesthesia in children during routine dental treatment.
- Trial name
- NCT02328729
- Testing
- mandibular block with Epinephrine, C-CLAD-IL with Epinephrine, Infiltration with Epinephrine
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Healthy Participants, Tooth Extraction
Application Of Dentapen In Dental Local Infiltration Anesthesia
The goal of this clinical study is to compare patients' self-reported pain and mental stress during infiltration anesthesia between conventional syringe and Dentapen.
- Conditions
- Healthy Participants, Tooth Extraction, Orthodontic Patients
- Trial name
- NCT07431801
- Testing
- computer controlled local anesthesia delivery device (Dentapen), Control
- Where
- Vietnam
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Son Hoang Le