Clinical trials: Cardiac Arrest, diet or lifestyle or exercise or nutrition or physical activity or counseling, open to volunteers
- Condition Cardiac Arrest
- Drug or intervention diet OR lifestyle OR exercise OR nutrition OR physical activity OR counseling
- Status Open to volunteers
Cardiac Arrest (CA), Resuscitated Sudden Cardiac Death
Long Term Follow-up of Cardiac Arrest Survivors Exposed to Ultra-rapid Cooling
Less than 10% of patients eliciting out-of-hospital cardiac arrest (OHCA) survive, although 30% can be resuscitated by Emergency services before admission in Intensive Care Units (ICU).
- Conditions
- Cardiac Arrest (CA), Resuscitated Sudden Cardiac Death, Post Cardiac Arrest Patient Who Was Treated by Hypothermia Protocol
- Trial name
- AFTERCOOL (NCT07028372)
- Testing
- Short Form Health Survey (SF-36), Modified Rankin Score (mRS), Activity of Daily Living (ADL) questionnaire
- Where
- 2 sites in France
- Volunteers
- 12 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Heart Arrest, Implantable Defibrillator User
Effectiveness of Exercise After an ICD
This study will test an exercise intervention (E-ICD) following an implantable cardioverter defibrillator.
- Conditions
- Heart Arrest, Implantable Defibrillator User, Physical Activity
- Trial name
- E-ICD (NCT03544489)
- Testing
- E-ICD Intervention
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- University of Washington
Sudden Cardiac Arrest
AI-guided Prediction and Treatment of Cardiac Arrest
Sudden cardiac arrest is a major health problem, and most people don't survive. One big reason is that even if resuscitation is successful, people commonly have recurrent cardiac arrests (rearrest).
- Trial name
- NCT07452016
- Testing
- Machine learning-guided cardiac arrest prediction device
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Cardiac Arrest (CA)
Effects of a Web-based Support Programme for Cardiac Arrest Survivors
The overall goal of this clinical trial is to learn if a web-based support programme can improve wellbeing in cardiac arrest survivors by helping them manage emotional, cognitive, and physical challenges.
- Trial name
- CARDIS (NCT07240714)
- Testing
- Digital Support Programme
- Where
- 9 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Linkoeping University
Mitral Annular Disjunction, Mitral Valve
Loop Recorder Implantation in Patients With Mitral Annular Disjunction
The goal of clinical trial is to prospectively collect data to investigate the prevalence of arrhythmia in young patients diagnosed with mitral annular disjunction who have no indication for implantable cardioverter defibrillator…
- Conditions
- Mitral Annular Disjunction, Mitral Valve, Arrhythmia Ventricular, Sudden Cardiac Death Due to Cardiac Arrhythmia
- Trial name
- ILR MAD IIT (NCT07436962)
- Testing
- loop recorder implantation
- Where
- Hungary
- Volunteers
- 20 people
- Sponsor
- Gottsegen National Cardiovascular Institute
Heart Failure With Reduced Ejection Fraction (HFrEF), Sudden Cardiac Death
Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator
This prospective, multicenter, open-label, randomized comparative effectiveness trial, titled CARVTOP-ICD, evaluates the impact of carvedilol versus metoprolol succinate in patients with heart failure with reduced ejection…
- Conditions
- Heart Failure With Reduced Ejection Fraction (HFrEF), Sudden Cardiac Death, Ventricular Arrhythmia, Implantable Cardioverter Defibrillator (ICD)
- Trial name
- CARVTOP-ICD (NCT06964464)
- Testing
- Metoprolol Succinate, Carvedilol
- Where
- 13 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- University of Rochester
Out of Hospital Cardiac Arrest, Inhospital Cardiac Arrest
Skeletal Muscle Mass on Prognosis and Recovery in Clinical Trial
The objective of this research project is to develop an automated muscle mass measurement system based on computed tomography (CT) images using deep learning and artificial intelligence, and to construct a prognostic prediction…
- Trial name
- NCT07034170
- Testing
- Enhanced Rehabilitation Program
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Adult Non-trauma Cardiac Arrest Resuscitation, Effectiveness of In-situ Simulation (ISS) Training
Effectiveness of In-Situ Simulation Training in Adult Non-Trauma Resuscitation: A Comparison of ISS and OSS Team Performance Using the A-C-L-S Model
This study employed a two-group non-randomized pre-post design to evaluate the effectiveness of interprofessional ISS training over one year at the National Taiwan University Hospital Yunlin Branch.
- Conditions
- Adult Non-trauma Cardiac Arrest Resuscitation, Effectiveness of In-situ Simulation (ISS) Training, Effectiveness of Off-site Simulation (OSS) Training, Improvement of Teamwork in Emergency Care Settings
- Trial name
- NCT07358793
- Testing
- In-situ Simulation (ISS) Training, Off-site Simulation (OSS) Training
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cognitive Impairment, Depression, Anxiety
intErnet-based iNterventions FOR Cardiac arrEst suRvivors
This randomized clinical trial will test whether an internet-based lifestyle intervention administered through a web app can foster Health Related Quality of Life in patients who survived an out-of-hospital cardiac arrest and…
- Conditions
- Cognitive Impairment, Depression, Anxiety, Cardiac Arrest, Quality of Life
- Trial name
- ENFORCER (NCT06395558)
- Testing
- Lifestyle intervention
- Where
- 2 sites in Italy
- Volunteers
- 106 people
- Sponsor
- Azienda Usl di Bologna
AAOCA, ACAOS
Speed-up the Diagnosis and Evaluation of anoMalous Coronary ARTery From the Aorta
Anomalous aortic origin of the coronary arteries (AAOCA) is a rare congenital disease and one of the leading causes of sudden cardiac deaths (SCD) in young athletes but also has a lethal presentation in adult age with myocardial…
- Conditions
- AAOCA, ACAOS, Anomalous Aortic Origin of the Coronary Artery (AAOCA), Anomalous Coronary Artery Arising From the Opposite Sinus
- Trial name
- SMART (NCT06705751)
- Testing
- Autonomic response in AAOCA
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- IRCCS Policlinico S. Donato
IVF Outcomes
HELIOS Advanced: Human Oocyte Illumination to Enhance Development
Oocytes need a lot of energy to complete meiosis and fertilize successfully. As women get older, the "power plants" of the cells (called mitochondria) don't work as well.
- Trial name
- HELIOS-A (NCT07425080)
- Testing
- Photobiomodulation
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Columbia University
Inherited Cardiac Conditions, Sudden Cardiac Arrest
Using Heart Electrical Signals to Study How Well Treatments Prevent Dangerous Heart Rhythms in Active People
The goal of this observational study is to learn if two specific heart electrical signal patterns can help in detecting the risk of dangerous heart rhythms in athletes, and to see if exercise-based tests can be used instead of…
- Conditions
- Inherited Cardiac Conditions, Sudden Cardiac Arrest, Ventricular Arrhythmia, Athlete
- Trial name
- ULTIMATE-A (NCT07014579)
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Sudden Cardiac Death, Cardiac Arrhythmias
Cardiovascular Pre-participation Screening in Children and Adolescents
Sports participation is strongly encouraged in children and adolescents, but intense training at early ages may reveal hidden heart conditions that increase the risk of sudden cardiac death.
- Trial name
- NCT07862504
- Testing
- Pre-participation clinical evaluation, Diagnostic Test: Resting 12-lead electrocardiogram, Diagnostic Test: Step test (Harvard step test)
- Where
- Brazil
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Post-Cardiac Arrest Syndrome, Post Cardiac Arrest Brain Injury
Cerebral Oximetry in Management of Post Cardiac Arrest
Resuscitation from a cardiac arrest is a common reason for admission to an intensive care unit (ICU). Because the brain is highly vulnerable to oxygen deprivation, severe brain damage often occurs during a cardiac arrest.
- Conditions
- Post-Cardiac Arrest Syndrome, Post Cardiac Arrest Brain Injury, Hypoxic-Ischemic Brain Injury
- Trial name
- COMPACT (NCT07829887)
- Testing
- Cerebral oximetry-guided treatment
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University of Calgary
CPR, Cardiac Arrest (CA)
Effect of an Educational Intervention on CPR Knowledge and Skills in Schoolchildren
This study aims to evaluate the effectiveness of a CPR intervention for children aged 7 and 8. Given the high prevalence of out-of-hospital cardiac arrests (OHCA) and the proven benefits of early CPR training, the study seeks to…
- Trial name
- NCT06929715
- Testing
- Intervention for Teaching the First Link in the Chain of Survival to 7- and 8-Year-Old Children
- Where
- Colombia
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Cardiac Arrest, Pulseless Electrical Activity
Surviving PEA in Roanoke (SPEAR) Study
The Carilion Clinic and Virginia Tech Carilion School of Medicine, in conjunction with Roanoke Fire-EMS, Botetourt County Department of Fire \& EMS and Salem Fire-EMS, are studying the outcomes of patients experiencing Pulseless…
- Trial name
- SPEAR (NCT05283850)
- Testing
- High Calcium, Low Sodium (HCLS) Crystalloid Therapy, High Calcium, High Sodium (HCHS) Crystalloid Therapy
- Where
- United States
- Volunteers
- 342 people
- Sponsor
- Carol Bernier
Acute Myocardial Infarction (AMI), Asystole
SPIKE FLOW Endocardial Lead Safety and Performance Study
The objective of this study is to assess the safety and performance of the SPIKE FLOW endocardial lead. Primary objectives are to assess: safety in terms of freedom from Serious Adverse Events(SADEs); performance in terms of Mean…
- Conditions
- Acute Myocardial Infarction (AMI), Asystole, Bradycardia, AV Block
- Trial name
- SPIKE FLOW (NCT07820072)
- Testing
- Lead insertion, lead removal
- Where
- 3 sites in Italy
- Volunteers
- 131 people
- Sponsor
- FIAB SpA
Out-Of-Hospital Cardiac Arrest
First Responder Airway & Compression Rate Trial
The First responder Airway \& Compression rate Trial (FACT) Study will address basic life support (BLS) treatments administered by Emergency Medical Services (EMS) first responders to patients who suffer a sudden circulatory…
- Trial name
- FACT (NCT05969028)
- Testing
- igel, Compression Rate
- Where
- United States
- Volunteers
- 4,200 people
- Sponsor
- University of Washington
Cardiac Arrest (CA), Anoxic Brain Injury
Early WAKE-up Predictors After Out-of-Hospital Cardiac Arrest
WAKE-OHCA is a prospective observational substudy of the Danish Out-of-Hospital Cardiac Arrest (DANOHCA) trial, identifier NCT05895838.
- Conditions
- Cardiac Arrest (CA), Anoxic Brain Injury, Comatose Survivors of Cardiac Arrest, EEG
- Trial name
- WAKE-OHCA (NCT06979700)
- Testing
- Automated Pupillometry, Transcranial Doppler Ultrasound, Optic Nerve Sheath Diameter
- Where
- 2 sites in Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Out-Of-Hospital Cardiac Arrest
Accuracy of EEG Slow Wave Activity in Predicting Favourable Outcome in Patients With Hypoxic Brain Injury - A Substudy of STEPCARE Trial
This is an observational substudy embedded in the STEPCARE Trial. The study involves EEG analysis, covered by the ethics approval of STEPCARE Trial.
- Trial name
- PROPEASTEPCARE (NCT06564675)
- Testing
- C-Trend Index
- Where
- 4 sites in Finland, Sweden
- Volunteers
- 300 people
- Sponsor
- University of Helsinki