Clinical trials: Cardiac Arrest, completed
Cardiopulmonary Arrest
Perception of Inappropriate CPR: a Multicenter International Cross-sectional Survey
The primary objective of this study is to determine how often cardiopulmonary resuscitation (CPR) is perceived as inappropriate by Healthcare Providers (HCPs) working in prehospital Ambulance Services and Emergency Departments.
- Trial name
- REAppropriate (NCT02356029)
- Where
- 5 sites in Belgium
- Volunteers
- 5,882 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Erythropoietin, Acute Kidney Injury
Evaluating Erythropoietin as an Indicator for Possible Kidney Injury After Cardiac Surgery
The purpose of the study is to evaluate kidney biomarkers and determine if there is a correlation between Erythropoietin (EPO) levels and acute kidney injury after cardiac surgery.
- Conditions
- Erythropoietin, Acute Kidney Injury, Renal Biomarker
- Trial name
- EPO (NCT01393418)
- Testing
- Cardiac Surgery
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Michigan
Cardiopulmonary Arrest
Measurement of Cerebral Flow Using Transfontanellar Doppler in Infants Under Cardiopulmonary Bypass
Transfontanellar Doppler can measure the velocity at both the carotid artery and the anterior cerebral artery during cardiopulmonary bypass in congenital heart disease patients.
- Trial name
- NCT01996020
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Seoul National University Hospital
Heart Arrest, Sport Injury
Tour de Borobudur Troponin Study on Predictors and Synergistic Role of MDA and Hs-CRP Levels
Prospective observational study to determine predictors that related to cardiac troponin I (cTnI) release, malondialdehyde (MDA) and high sensitivity C Reactive Protein (hs-CRP) after Tour de Borobudur (TdB) 2017
- Conditions
- Heart Arrest, Sport Injury, Inflammatory Response, Oxidative Stress
- Trial name
- TdBTS (NCT03310450)
- Testing
- 140kms cycling
- Where
- Indonesia
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Universitas Negeri Semarang
Ischemic Heart Failure
LifeVest Wearable Cardioverter Defibrillator WEARIT-III Registry
The WEARIT-III registry enrolls subjects with ischemic cardiomyopathy and heart failure (including NYHA II, III, IV and an ejection fraction ≤ 35%) who wear a medically prescribed ZOLL LifeVest Wearable Defibrillator.
- Trial name
- WEARIT-III (NCT02700880)
- Testing
- LifeVest
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Zoll Medical Corporation
Cardiac Arrest
Washington Study of Hemofiltration After Out-of-Hospital Cardiac Arrest
The purpose of this study is to assess the feasibility of hemofiltration in patients resuscitated from cardiac arrest. Cardiac arrest is the loss of mechanical activity of the heart including the loss of detectable pulse, or…
- Trial name
- NCT01509040
- Testing
- Standard Care, Low Volume Hemofiltration, High Volume Hemofiltration
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Washington
Cardiac Arrest
OPALS Cardiac Arrest Database (OCAD)
To provide the infrastructure to answer prehospital research questions posed by scientists at academic health science centers and policy makers at multiple levels of government.
- Trial name
- NCT00300703
- Where
- 11 sites in Canada
- Volunteers
- 1,538 people
- Sponsor
- Ottawa Hospital Research Institute
Arrhythmia, Cardiovascular Diseases
Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)
To compare conventional treatment of congestive heart failure (CHF) with two experimental interventions: amiodarone and an implantable cardioverter-defibrillator (ICD).
- Conditions
- Arrhythmia, Cardiovascular Diseases, Death, Sudden, Cardiac, Heart Diseases
- Trial name
- NCT00000609
- Testing
- amiodarone, defibrillators, implantable
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Heart Arrest, Birth Asphyxia
SI + CC Versus 3:1 C:V Ratio During Neonatal CPR
Research question In newborn infants requiring CPR, does CC superimposed by sustained inflation compared to 3:1 compression to ventilation ratio improves return of spontaneous circulation? Overall objective: CC superimposed by…
- Conditions
- Heart Arrest, Birth Asphyxia, Bradycardia
- Trial name
- SURV1VE (NCT02858583)
- Testing
- CC+SI, 3:1 C:V
- Where
- 4 sites in Austria, Canada
- Volunteers
- 27 people
- Sponsor
- University of Alberta
Cardiac Arrest, Perioperative Complication
The Factors Associated 30-day Mortality After Perioperative Cardiac Arrest in Adults Undergoing Non-cardiac Surgery.
Perioperative cardiac arrest (PCA) in patients undergoing noncardiac surgery is a rare but potentially catastrophic event associated with high mortality.
- Trial name
- NCT06712134
- Volunteers
- 105 people
- Sponsor
- Siriraj Hospital
Neurological Prognosis Cardiac Arrest
EEG and SEP Evaluation for Good and Poor Neurological Prognosis After Cardiac Arrest
Hypoxic-Ischemic-encephalopathy (HIE) is a severe and frequent neurological complication of successful cardiopulmonary-resuscitation after cardiac arrest (CA).
- Trial name
- ProNeCA (NCT03849911)
- Testing
- Neurophysiological Prognosis, Multimodal Prognosis for poor early neurological outcome
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Hypothermia, Heart Arrest
Haemostasis and Therapeutic Hypothermia
The purpose of this study is to investigate, if the haemostasis is impaired in cardiac arrest patients during therapeutic hypothermia compared with normothermia.
- Trial name
- NCT02179021
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- University of Aarhus
Cardiomyopathy, Heart Failure
An Arrhythmia Risk Predictor Trial
This prospective single-center study is an observational risk stratification trial in about 250 patients with standard indications for ICD treatment.
- Trial name
- NCT02010515
- Where
- Germany
- Volunteers
- 282 people
- Sponsor
- University Medical Center Goettingen
Cardiopulmonary Arrest
Extension of Rapid Response Team Operation Time and Cardiopulmonary Resuscitation Incidence
Although early rapid response team was reported as a full-time operating system, similar efficacy of part-time rapid response team has been recently reported.
- Trial name
- NCT05712915
- Testing
- RRT operation
- Where
- South Korea
- Volunteers
- 142,088 people
- Sponsor
- Dong-A University Hospital
Cardiopulmonary Resuscitation, Cardiopulmonary Arrest
Evaluation of Efficacy of Online Real-time Home CPR Training Program
The purpose of this study is to evaluate the effectiveness of a real-time home CPR(cardiopulmonary resuscitation) training program. The study participants will be allocated to two different CPR training programs.
- Conditions
- Cardiopulmonary Resuscitation, Cardiopulmonary Arrest, Education
- Trial name
- NCT05023616
- Testing
- Real-time home CPR training, Conventional CPR training
- Where
- South Korea
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Out-Of-Hospital Cardiac Arrest
Sex-unique Disparities in Survival and Resuscitation After Out-of-hospital Cardiac Arrest - a Danish Analysis
The goal of this observational study is to investigate characteristics in out-of-hospital cardiac arrests (OHCA) related to sex differences.
- Trial name
- NCT05583084
- Testing
- Investigation
- Volunteers
- 27,000 people
- Sponsor
- Prehospital Center, Region Zealand
Cardiac Arrest
Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or Tachycardia
The primary objective of the trial is to determine if survival to hospital discharge is improved with early therapeutic administration of a new Captisol-Enabled formulation of IV amiodarone (Nexterone-PM101) compared to placebo.
- Trial name
- ALPS (NCT01401647)
- Testing
- amiodarone, Lidocaine, Normal saline
- Where
- 9 sites in United States, Canada
- Volunteers
- 3,024 people
- Sponsor
- University of Washington
Prediction by the Synek Score of Poor Neurological Outcome in Postanoxic Comatose Patients Treated With Induced Hypothermia
Synek Score to Predict Poor Neurological Outcome Post Resuscitated Cardiac Arrest
Resuscitated cardiac arrest (CA) is a frequent cause of admission in intensive care unit (ICU). Neurological state of postanoxic comatose patients can evolve either towards the absence of awakening or towards a more or less…
- Trial name
- NCT03737747
- Testing
- induced hypothermia
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cardiac Arrest, Cognitive Function
Brain Function After Cardiac Arrest (Measured With FMRI and Cognitive Tests)
The aim of this longitudinal study is to determine whether brain function is affected after a cardiac arrest. The primary question is whether cognitive function is affected after cardiac arrest and whether it changes over time…
- Trial name
- BRAINnHEART (NCT03579498)
- Where
- 2 sites in Norway, Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Sudden Cardiac Death
Predictive Risk Stratification Through T Variability in ICD Patients Without Pacing Indications
The aim of the study is to assess the negative predictive value of the T amplitude variance as a method for risk stratification for patients with an increased risk for SCD.
- Trial name
- Prediction (NCT00560768)
- Testing
- Ovatio VR 6250 or DR6550
- Where
- 30 sites in United States, Canada and 2 more
- Volunteers
- 198 people
- Sponsor
- LivaNova