Clinical trials: Cardiac Arrest With Successful Resuscitation
Cardiac Arrest With Successful Resuscitation, Hypoxia, Brain
Sedation, Temperature and Pressure After Cardiac Arrest and Resuscitation
The STEPCARE-trial is a 2x2x2 randomised trial studying patients who have been resuscitated from cardiac arrest and who are comatose.
- Trial name
- STEPCARE (NCT05564754)
- Testing
- Feedback-controlled temperature device, High MAP, Deep sedation
- Where
- 56 sites in Australia, Belgium and 13 more
- Volunteers
- 3,500 people
- Sponsor
- Region Skane
Cardiac Arrest, Out-Of-Hospital, Cardiac Arrest With Successful Resuscitation
CardioPulmonary Resuscitation With Argon (CPAr) Trial
Preclinical studies suggest that argon (Ar) might diminish the neurological and myocardial damage after any hypoxic-ischemic insult.
- Trial name
- CPAr (NCT05482945)
- Testing
- Noble gas Argon
- Where
- 9 sites in Italy
- Volunteers
- 120 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Alpine Accident, Frostbite
10-years Nationwide Alpine Accidents in Austria
This observational study intends to analyze the characteristic of specific accidents happened in Austrian's mountainous regions.
- Conditions
- Alpine Accident, Frostbite, Cardiopulmonary Arrest With Successful Resuscitation, Lightning Injuries
- Trial name
- NCT03405467
- Testing
- general and specific data
- Where
- Austria
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Echocardiography, Transesophageal, In-hospital Cardiac Arrest
RescueTEE for In-hospital Cardiac Arrest (ReTEECA Trial)
ReTEECA Trial. Rescue TransEsophageal Echocardiography for In-Hospital Cardiac Arrest. This trial is aimed at studying the utility and interventional outcomes of rescue transesophageal echocardiography (RescueTEE) to aid in…
- Conditions
- Echocardiography, Transesophageal, In-hospital Cardiac Arrest, Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation
- Trial name
- ReTEECA (NCT04220619)
- Testing
- Tranesophageal Echocardiography
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cardiac Arrest With Successful Resuscitation
Hemodynamic Optimization Through Pleth Variability Index for OHCA
Less than half of the patients suffering from sudden cardiac arrest arrive at the hospital alive. Within these survivors less than half will be discharged alive from the hospital without being severely disabled.
- Trial name
- HemOpt-PVI (NCT03841708)
- Testing
- Pleth variability index, Standard non invasive monitoring
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- Stefano Malinverni, MD
Cardiac Arrest, Cardiac Arrest, Out-Of-Hospital
Resuscitation and Capillary Reperfusion
Persistent microperfusion alterations after return of spontaneous circulation (ROSC) are associated with poor survival. To our knowledge, no human studies evaluating microperfusion during cardiopulmonary resuscitation (CPR) with…
- Conditions
- Cardiac Arrest, Cardiac Arrest, Out-Of-Hospital, Cardiopulmonary Arrest, Cardiopulmonary Arrest With Successful Resuscitation
- Trial name
- ReCapp (NCT04791995)
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Sepsis, Septic Shock
The Role of Serotonin in Intensive Care Patients
Sepsis, cardiac arrest and multiple trauma are potentially life-threatening conditions and common reasons for intensive care unit (ICU) admission.
- Conditions
- Sepsis, Septic Shock, Cardiac Arrest With Successful Resuscitation, Multiple Trauma
- Trial name
- SERO-22 (NCT05386199)
- Where
- Norway
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cardiac Arrest With Successful Resuscitation, Mechanical Ventilation
Study of Ventilator Associated Event During Intensive Care After Resuscitated Cardiac Arrest.
The aim is to describe the incidence, characteristics, risk factors and outcome of complications acquired under mechanical ventilation (called ventilator-associated events) according to the new CDC criteria, in a population of…
- Trial name
- VAE-ACR (NCT06466980)
- Testing
- Ventilator associated event
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Sud Francilien
Cardiac Arrest
Survey of Attitudes and Factors Associated With CPR in an Older Population
The goal of this study is to conduct a survey to better understand the factors associated with undertaking cardiopulmonary resuscitation (CPR) training and performing CPR in an emergency situation.
- Trial name
- NCT00665288
- Where
- Canada
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation
Pupillometry and Somatosensory Evoked Potential in Cardiac Arrest
Somatosensory Evoked Potentials (SSEP) and Pupillary Light Reflex (PLR) are key methods for neurologic prognostication in comatose survivors of cardiac arrest.
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation, Resuscitation
- Trial name
- PASCA (NCT04720482)
- Testing
- Somatosensory Evoked Potentials, Automated Pupillometry
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Sahlgrenska University Hospital
Cardiac Arrest With Successful Resuscitation
Study of Brain Cools Device in Patients Resuscitated From Cardiac Arrest
This submission is a pilot in which the new IQool Warming System device will be used to maintain the temperature of adult patients in cardiac arrest within a range of within a range of 32°C to 38.5°C (89.6°F to 101.3°F).
- Trial name
- NCT03889340
- Testing
- IQool
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Adam Frisch
Cardiac Arrest With Successful Resuscitation
A Novel Patient Decision Aid for Surrogate Decision Makers of Comatose Survivors of Cardiac Arrest
This study will test the feasibility and acceptability of deploying a decision aid for surrogate decision makers of comatose survivors of cardiac arrest early during hospitalization.
- Trial name
- NCT03908346
- Testing
- Decision Aid for Surrogate Decision Makers of Comatose Survivors of Cardiac Arrest
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Colorado, Denver
Cardiac Arrest With Successful Resuscitation, Hypothermia
Skeletal Muscle Paralysis in Hypothermic Patients After Cardiac Arrest
Mild hypothermia improves neurological outcome after cardiac arrest. Neuromuscular blockers are in use, together with analgesia and sedation, during the cooling process in many centers to prevent shivering.
- Conditions
- Cardiac Arrest With Successful Resuscitation, Hypothermia, Skeletal Muscle Relaxant Overdose
- Trial name
- RELAX (NCT01719770)
- Testing
- rocuronium
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Out-Of-Hospital Cardiac Arrest, Cardiac Arrest
Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest
Comatose patients resuscitated from Out-of-Hospital Cardiac Arrest (OHCA) often develop a complicated systemic inflammatory response and have a poor prognosis with neurological damage being the most common cause of death.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Cardiac Arrest, Cardiac Arrest With Successful Resuscitation, Post Cardiac Arrest Syndrome
- Trial name
- STEROHCA (NCT04624776)
- Testing
- Methylprednisolone, Isotonic saline
- Where
- 2 sites in Denmark
- Volunteers
- 158 people
- Sponsor
- Christian Hassager
Cardiorespiratory Arrest, Cardiopulmonary Arrest With Successful Resuscitation
Effectiveness of Online Training in Cardiopulmonary Resuscitation Maneuvers for a Network of Volunteers.
Background: Cardiorespiratory arrest (CPA) occurs when there is a cessation of cardiac mechanical activity, typically diagnosed by the absence of consciousness, pulse, and breathing.
- Trial name
- EFORCP (NCT06275984)
- Testing
- online CPR-AED training
- Where
- Spain
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Cardiac Arrest With Successful Resuscitation, Cardiac Arrest, Cause Unspecified
Optimization of Transport and Use of a Mobile ECMO Team in Patients With Sudden Cardiac Arrest in the Moravian-Silesian Region
This study evaluates the feasibility of implementing a mobile extracorporeal membrane oxygenation (ECMO) team and optimizing patient transport logistics.
- Trial name
- NCT07009652
- Testing
- Extracorporeal cardiopulmonary resuscitation (ECPR)
- Where
- 2 sites in Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Cardiopulmonary Arrest With Successful Resuscitation, Education, Nursing
Basic Life Support (BLS) Training by Homemade Manikin
The experimentally planned research was carried out between the dates of 01.06.2021-10.11.2021 with the students of ……………. Faculty of Health Sciences, Department of Nursing.
- Trial name
- NCT05191992
- Testing
- CPR training with e-learning with a handmade mannequin.
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation
Impact of NIRS-guided Cardiopulmonary Resuscitation After Cardiac Arrest on Resuscitation Rate
Sudden cardiac death is one of the main causes of morbidity and mortality worldwide. Cardiac arrest requires prompt intervention by cardiopulmonary resuscitation (CPR).
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation, Cerebral Oxygenation
- Trial name
- NICA (NCT03911908)
- Testing
- Cerebral oximetry (near infrared) based CPR-Algorithm
- Where
- Germany
- Volunteers
- 360 people
- Sponsor
- Dr. Serge Thal
Neurological Outcome, Cardiac Arrest
Out-of-hospital Cardiac Arrest (OHCA) Biomarkers
Few early prognostic indicators are currently available for patients' families and clinicians following out of hospital cardiac arrest (OHCA), and blood biomarkers may be of prognostic value in these cases.
- Conditions
- Neurological Outcome, Cardiac Arrest, Out-Of-Hospital Cardiac Arrest, Brain Anoxia Ischemia
- Trial name
- NCT03112486
- Testing
- blood draw
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Florida
Cardiogenic Shock, Ventricular Arrythmia
Innovative Technologies for the Treatment of Pulmonary and Heart Failure
The purpose of the program. Formulation of new treatments for heart and pulmonary failure through using organ-replacing technologies.
- Conditions
- Cardiogenic Shock, Ventricular Arrythmia, Cardiac Arrest With Successful Resuscitation, Sepsis
- Trial name
- NCT05090930
- Testing
- HA330 - Jafron Biomedical Co., Ltd., China - extracorporeal hemocorrection, CytoSorb (CytoSorbents Corp., USA) - an extracorporeal cytokine adsorber
- Where
- Kazakhstan
- Volunteers
- 100 people
- Sponsor
- National Research Center for Cardiac Surgery, Kazakhstan