Clinical trials: Cardiac Arrhythmias
Healthy, Arrhythmia
Prospective Study to Validate the Clinical Accuracy of the Norbert Device to Measure Pulse Rate
The study will evaluate the mean average error (MAE) of measuring pulse rate using the Norbert Device (ND) as compared to a reference heart rate measured using an electrocardiogram (ECG).
- Trial name
- NCT05640323
- Testing
- Norbert Device
- Where
- 2 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Norbert Health
Hypertrophic Cardiomyopathy
Sleep Apnea and Hypertrophic Cardiomyopathy (HCM)
The investigators are trying to find out how common sleep apnea is in hypertrophic cardiomyopathy. The purpose of this study is to see if sleep apnea is common in hypertrophic cardiomyopathy and if its presence is associated with…
- Trial name
- NCT03327623
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Heart Rate Low, Anesthesia; Functional
A Study on Safety and Efficacy of Propofol in Small Children Under 2 Years of Age
This retrospective study the safety and efficacy of intravenous propofol used in children under 2 years of age during general anesthesia for surgery.
- Trial name
- NCT03132688
- Testing
- Propofol
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Atrial Fibrillation
Autoimmunity in the Pathogenesis of AF
This research study is being done to find out whether autoimmune mechanisms are associated with the development of atrial fibrillation.
- Trial name
- NCT03498729
- Testing
- Peripheral Blood Sample
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Atrial Fibrillation
Validation of ECG Measurement and Atrial Fibrillation Detection
Atrial fibrillation (AFib) is a common type of cardiac arrhythmia in clinical practice, affecting millions of people worldwide. Early detection and treatment of atrial fibrillation are crucial in preventing serious complications…
- Trial name
- NCT06099249
- Testing
- ASUS ECG App
- Volunteers
- 602 people, healthy volunteers welcome
- Sponsor
- ASUSTek Computer INC.
Atrial Fibrillation
Validation of Software for Assessment of Atrial Fibrillation From Data Acquired by a Wearable Smartwatch
The goal of this study is to validate the Fitbit ECG software algorithm's ability to detect atrial fibrillation using data derived from a Fitbit wrist-worn consumer device that features a single lead ECG.
- Trial name
- NCT04176926
- Testing
- Electrocardiogram
- Where
- 10 sites in United States, Greece
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- Fitbit LLC
Atrial Fibrillation
Replication of the RELY Anticoagulant Trial in Healthcare Claims Data
Investigators are building an empirical evidence base for real world data through large-scale replication of randomized controlled trials.
- Trial name
- NCT04593043
- Testing
- Warfarin, Dabigatran
- Where
- United States
- Volunteers
- 78,140 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Embolic Stroke of Undetermined Source
Identification of New Markers of Atrial Myopathy in Patients With Embolic Stroke of Undetermined Source (ESUS) From MRI 4D Data
Atrial myopathy is considered to be the underlying cause of a large proportion of embolic strokes of undetermined source. However, the definition of this atrial condition is not well delineated while its identification could lead…
- Trial name
- IRM 4D-AVC (NCT04717843)
- Testing
- 4D Flow MRI, Medical consultation with 12 leads ECG, Holter ECG
- Where
- 3 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Complication Due to Immunization
Cardio-respiratory Events and Inflammatory Response After Primary Immunization in Preterm Infants
Background: Inflammation may depress respiration in neonates. The aim of this study was to establish a link between post-immunization inflammation and cardio-respiratory events (CRE).
- Trial name
- NCT02726178
- Testing
- Advil® Pediatric drops for infants
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Atrial Fibrillation, Catheter Ablation
Post-Ablation Pericarditis Reduction Study
There has not been a prospective, randomized controlled trial of colchicine to reduce post-AF ablation pericarditis in an era of newer AF ablation techniques.
- Conditions
- Atrial Fibrillation, Catheter Ablation, Pericarditis
- Trial name
- PAPERS (NCT04906720)
- Testing
- Colchicine
- Where
- United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- St. Vincent Cardiovascular Research Institute
Long QT Syndrome
Effect of Oral GS-6615 on Dofetilide-Induced QT Prolongation, Safety, and Tolerability in Healthy Adults
This study will evaluate the effect of oral GS-6615 on QTc interval in healthy adults with dofetilide-induced QTc prolongation.
- Trial name
- NCT02365532
- Testing
- GS-6615, Dofetilide
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
Arterial Thromboembolic Events, Atrial Fibrillation
Effectiveness of Bridging Anticoagulation for Surgery (The BRIDGE Study)
Blood thinners, such as warfarin, prevent blood clots from forming, thereby reducing the risk of a stroke or heart attack. When people undergo surgery or certain procedures, they must stop using warfarin to prevent too much…
- Trial name
- NCT00786474
- Testing
- Dalteparin
- Where
- United States
- Volunteers
- 1,884 people, healthy volunteers welcome
- Sponsor
- Duke University
Arrhythmias, Cardiac, Tachycardia, Ventricular
Cardiac Arrhythmias at Extreme Altitude
Background: Exposure to high altitudes has been associated with an increased risk of cardiac arrhythmias in healthy subjects and an increased risk of sudden cardiac death.
- Conditions
- Arrhythmias, Cardiac, Tachycardia, Ventricular, Tachycardia, Supraventricular, Bradycardia
- Trial name
- SUMMIT (NCT05676398)
- Testing
- Ambulatory rhythm recording
- Where
- Nepal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Lung Neoplasms, Respiratory Failure
Clearance Of Mucus In Stents (COMIS)
The goal of this clinical research study is to compare the effects of sodium bicarbonate to normal saline when used for clearing mucus blockage in patients with airway stents.
- Conditions
- Lung Neoplasms, Respiratory Failure, Pneumonia, Acute Coronary Syndromes
- Trial name
- NCT01370278
- Testing
- Normal Saline, Sodium Bicarbonate
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Death, Sudden, Cardiac, Electrocardiogram QT Prolonged
Risk of Sudden Cardiac Death in UN Athletes
The detection of sudden cardiac death risk in athletes is a topic of great relevance in the field of sports physiotherapy and physical activity.
- Conditions
- Death, Sudden, Cardiac, Electrocardiogram QT Prolonged, Athlete Heart, Athletic Injuries
- Trial name
- Suddendeath (NCT06518252)
- Where
- Colombia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Bradycardia
Can Medical Personnel Properly Proceed in the Case of a Patient With Bradycardia?
The study aims to assess the regularity of the proceedings in the case of a patient with bradycardia ECG.
- Trial name
- NCT02711748
- Testing
- electrostimulation, cardiopulmonary resuscitation
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Ventricular Tachycardia
MANAGE-VT Registry - MANAGEment of Ventricular Tachycardia Outcomes Registry
Data collection registry for patients with ventricular tachycardia to help physicians give better care for patients clinically and procedurally.
- Trial name
- MANAGE-VT (NCT06455488)
- Testing
- Ventricular Tachycardia Ablation, ICD Implant, Antiarrhythmic drug
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- CorVita Science Foundation
Atrial Fibrillation, Sepsis
Continuous Ambulatory Cardiac Monitoring for Recurrent Atrial Fibrillation After Sepsis
To detect atrial fibrillation after infection.
- Conditions
- Atrial Fibrillation, Sepsis, Infections, Cardiac Arrhythmia
- Trial name
- CAMS-AF (NCT05217485)
- Testing
- Zio 14-day cardiac patch
- Where
- United Kingdom
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Medical Education, Emergency Medicine
Comparison of Task Trainer and Virtual Reality Approaches in Dysrhythmia Management Education
The aim of this randomized controlled simulation-based educational study was to compare the effectiveness of virtual reality (VR)-based and task trainer-based training in improving dysrhythmia management performance among intern…
- Conditions
- Medical Education, Emergency Medicine, High-Fidelity Simulation Training, Virtual Reality Simulation
- Trial name
- NCT07892391
- Testing
- Virtual Reality-Based Dysrhythmia Management Training, Task Trainer-Based Dysrhythmia Management Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Atrial Fibrillation, Postoperative Complications
Landiolol for Prevention of Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
Postoperative atrial fibrillation (POAF) is the most common arrhythmia after cardiac surgery with incidences ranging from 20% to 40% with the consequence of increasing mortality, morbidity, and hospital length of stay, as well as…
- Trial name
- LANDI-POAF (NCT05084118)
- Testing
- Landiolol HCl
- Where
- Austria
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna