Clinical trials: Cardiac Autonomic Function
Type 2 Diabetes, Diabetes Mellitus, Type 2
Heart Rate Variability-Guided Exercise Training in Type 2 Diabetes
The primary aim of this randomized clinical trial is to determine the effectiveness of a 16 wk individualized aerobic exercise program, using heart rate variability to guide the exercise prescription, for increasing aerobic…
- Conditions
- Type 2 Diabetes, Diabetes Mellitus, Type 2, Type 2 Diabetes Mellitus in Obese
- Trial name
- NCT04910997
- Testing
- Aerobic exercise training
- Where
- United States
- Sponsor
- University of Illinois at Chicago
Pain Perception, Autonomic Nervous System Functioning
Music-based Intervention for the Reduction of Pain
This study aims to compare the impact of listening to frequency-modulated music vs. non-modulated music (both researcher-selected), and to test whether there are differential effects on pain and stress perception.
- Trial name
- MINTREP (NCT02991014)
- Testing
- researcher-selected frequency-modulated music, researcher-selected non-modulated music, participant-selected non-modulated music
- Where
- 2 sites in Austria, Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Ischemic Preconditioning, Autonomic Nervous System (ANS) Functioning and Mood State
The Impact of Ischemic Preconditioning on Exercise Performance and Physiological Function
Ischemic Preconditioning has been confirmed to prevent long-term ischemic damage to tissues, among which the improvement of autonomic nerve system function may be one of its mechanisms of action.
- Trial name
- NCT07146399
- Testing
- Ischemic Preconditioning
- Where
- China
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ziyue Ou
Type 1 Diabetes Mellitus
To Evaluate if Wide Blood Sugar Fluctuations Lead to Injury of Heart Function and Heart Nerves
This proposal will test if, in patients with type 1 diabetes, wide blood glucose fluctuations lead to the injury to heart nerves , called cardiac autonomic neuropathy (CAN), and to impaired heart contractile (pumping) function…
- Trial name
- NCT01170832
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Heart Failure
Safety Study of Pyridostigmine in Heart Failure
Heart failure, a common heart disease affecting nearly 6 million Americans, is associated with high rates of hospitalization and death.
- Trial name
- APP-HF (NCT01415921)
- Testing
- Pyridostigmine Bromide
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- NYU Langone Health
Diabetes Mellitus Type 2, Heart Failure
Heart Failure in Patients With Diabetes: Cells, Crosstalk and Consequences
This will be an observational study to explore differences in pathophysiology between groups of people with and without heart failure (HF) (reduced and preserved ejection fraction) and with and without diabetes mellitus (DM) with…
- Conditions
- Diabetes Mellitus Type 2, Heart Failure, HFrEF - Heart Failure With Reduced Ejection Fraction, HFpEF - Heart Failure With Preserved Ejection Fraction
- Trial name
- NCT06774014
- Where
- United Kingdom
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Reduction of Blood Pressure in Hypertensive Patients., Improvement of Cardiovascular Autonomic Control.
Effects of Inspiratory Muscle Training on Cardiovascular Function in Hypertension.
The purpose of this study is to determine inspiratory muscle training effects on blood pressure, functional capacity and quality of life in hypertensive patients.
- Conditions
- Reduction of Blood Pressure in Hypertensive Patients., Improvement of Cardiovascular Autonomic Control., Improvement of Functional Capacity., Improvement of Quality of Life.
- Trial name
- TREMVEN (NCT01250444)
- Testing
- Inspiratory Muscle Training
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Cerebral Palsy, Autonomic Nerveus System
BioFeedBack Breathing Training Influence Cardiac Autonomic Nervous System in Children With Cerebral-Palsy.
The effect of breathing biofeedback training to influence the function of the cardiac autonomic nervous system at rest and in activity in children with cerebral palsy.
- Trial name
- NCT01872507
- Testing
- Biofeedback training
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Disorders of the Autonomic Nervous System, Cardiovascular Abnormalities
Electrocardiographic Autonomic Function Measures in Mechanically Ventilated Patients
This research proposal has two main objectives. The first is to increase understanding of the underlying physiological interactions that occur between the cardiovascular, pulmonary, and ANS during transition between positive…
- Conditions
- Disorders of the Autonomic Nervous System, Cardiovascular Abnormalities, Respiratory Disorders
- Trial name
- NCT00844935
- Where
- United States
- Sponsor
- University of California, San Francisco
Mood Modulation, Modulation of Cognition
Investigation of the Acute Cognitive, Mood and Autonomic Effects of Hops in Healthy Participants
Hops have been used for many years for their supposed sedative and anxiety reducing properties and can be found in many natural remedies for stress, anxiety and sleeping that are already available to buy.
- Trial name
- NCT01376869
- Testing
- Hops Extract
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Recurrent Pregnancy Loss, Anxiety
Cardiac Autonomic and Anxiety Regulation Via Closed-loop nEurofeedback in Recurrent Pregnancy Loss
The goal of this clinical trial is to learn whether right dorsolateral prefrontal cortex (right DLPFC)-targeted fNIRS-BCI online closed-loop neurofeedback, delivered with slow-wave acoustic cueing, can reduce anxiety symptoms and…
- Trial name
- CARE-RPL (NCT07325370)
- Testing
- Right DLPFC fNIRS-BCI closed-loop neurofeedback (real feedback)
- Where
- 2 sites in China
- Volunteers
- 62 people
- Sponsor
- Shenyang Medical College
Heart Rate Variability
Effects of Arm Crank Versus Treadmill Exercises on Heart Rate Variability in Adult Subjects.
Cardiovascular response to exercise affects the capacity of all body organs depending upon intensity, duration and mode of exercises.
- Trial name
- NCT03068182
- Testing
- Arm crank, Treadmill, Exercise
- Where
- Saudi Arabia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University