Clinical trials: Cardiac Autonomic Function, open to volunteers
Spinal Cord Injury
Cardiovascular Autonomic Function After Resistance Training
The purpose of this clinical trial is to evaluate whether an 8-week upper-limb resistance training program improves cardiovascular autonomic function in adults with chronic spinal cord injury (SCI).
- Trial name
- NCT07725952
- Testing
- Upper-Limb Resistance Training
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Pusan National University Yangsan Hospital
Epilepsy
Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male Epileptic Patients With Hypovitaminosis D
The goal of this clinical trial is to see the effect of vitamin D3 supplementation on cardiac autonomic nerve function in male epileptic patients with hypovitaminosis D that weather vitamin D improves heart rate variability or…
- Trial name
- NCT07085598
- Testing
- Vitamin D
- Where
- Bangladesh
- Volunteers
- 15 people
- Sponsor
- Bangladesh Medical University
Autonomic Nervous System (ANS) Functioning and Mood State, Heart Rate Variability (HRV)
taVNS During Multi-site HRV Measurement: Reliability & Agreement Study
This study examines the reliability and agreement of autonomic nervous system measurements obtained from different anatomical sites during transcutaneous auricular vagus nerve stimulation (taVNS).
- Conditions
- Autonomic Nervous System (ANS) Functioning and Mood State, Heart Rate Variability (HRV), Blood Pressure Monitoring, Transcutaneous Electric Nerve Stimulation
- Trial name
- taVNS-HRV (NCT07548723)
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Stroke
COMPARISON OF BREATHING AND SUBOCCIPITAL RELEASE IN STROKE
The aim of this study is to investigate the positive effects of deep, slow breathing exercises and suboccipital relaxation, when added to a routine physiotherapy and rehabilitation program, on autonomic, motor, cognitive, and…
- Trial name
- NCT07725471
- Testing
- Breathing Exercise, Suboccipital Release, Standard treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara Yildirim Beyazıt University
Acute Ischemic Stroke, Transient Ischemic Attack
Imaging and Serological Biomarkers of Autonomic Dysfunction After Ischemic Stroke
The goal of this observational study is to to investigate the prevalence and time course of autonomic dysfunction in acute ischemic stroke patients; to evaluate the influence of lesion location on autonomic dysfunction; to…
- Trial name
- ARIADNE (NCT06740942)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Major Depressive Disorder
Intradermal Acupuncture as an Adjunct to SSRI Tapering in Major Depressive Disorder
This randomized controlled trial aims to evaluate the clinical efficacy of intradermal acupuncture as an adjunctive intervention to assist selective serotonin reuptake inhibitor (SSRI) dose reduction or discontinuation in adult…
- Trial name
- NCT07390981
- Testing
- Selective Serotonin Reuptake Inhibitors (SSRIs), Intradermal Acupuncture
- Volunteers
- 114 people
- Sponsor
- First People's Hospital of Hangzhou
Occupational Health, Autonomic Nervous System (ANS) Functioning and Mood State
Office Massage Effects on HRV and Stress
This study is a randomized controlled trial designed to investigate which of three short office massage types (head, neck/shoulder area, or hand) is most effective for reducing chronic stress in women who perform sedentary office…
- Conditions
- Occupational Health, Autonomic Nervous System (ANS) Functioning and Mood State, Stress
- Trial name
- NCT07272031
- Testing
- Head Massage Intervention, Cervical Area Massage Intervention, Hand Massage Intervention
- Where
- Latvia
- Volunteers
- 140 people
- Sponsor
- Riga Stradins University
Atrial Fibrillation (AF), Cardiovascular Diseases
Low-Intensity Focused Ultrasound Targeting the Stellate Ganglion for Regulating Autonomic Nerve Function and Sleep Quality in Perioperative Patients With Cardiovascular Diseases
The goal of this multicenter, double-blind, randomized controlled trial is to evaluate the efficacy and safety of low-intensity focused ultrasound (LIFU) stellate ganglion modulation for improving autonomic function and sleep…
- Trial name
- US-REST (NCT07595068)
- Testing
- Low-intensity focused ultrasound (LIFU) targeting the left stellate ganglion
- Where
- 7 sites in China
- Volunteers
- 200 people
- Sponsor
- Renmin Hospital of Wuhan University
BPPV, Stress and Anxiety
Heart Rate Variability in Benign Paroxysmal Positional Vertigo
Benign paroxysmal positional vertigo (BPPV) is the most common peripheral vestibular disorder. Although the pathophysiology of BPPV is mainly attributed to the displacement of otoconia within the semicircular canals, recent…
- Trial name
- BPPV-HRV (NCT07472998)
- Testing
- Short-term HRV measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Long COVID, Heart Rate Variability (HRV)
Effects os Physiotherapeutic Rehabilitation on Function Autonomic and Inflammatory in Patients With Long Covid
Introduction: Long COVID is characterized by persistent symptoms that persist for weeks or months after the acute phase of infection, with a significant impact on the cardiovascular and autonomic systems.
- Conditions
- Long COVID, Heart Rate Variability (HRV), Cardiac Biomarkers, Inflammatory Biomarkers
- Trial name
- LongCovidRehab (NCT07046208)
- Testing
- physiothreapy protocol
- Volunteers
- 58 people
- Sponsor
- Universidade do Estado do Pará
Chronic Obstructive Pulmonary Disease Moderate, Chronic Obstructive Pulmonary Disease Severe
Respiratory and Cardiovascular Alterations in Patients With Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a lung condition characterized by chronic respiratory symptoms (dyspnoea, cough, sputum production and/or exacerbations) due to abnormalities of the airways (e.g.
- Conditions
- Chronic Obstructive Pulmonary Disease Moderate, Chronic Obstructive Pulmonary Disease Severe, Cardiovascular Diseases, Quality of Life
- Trial name
- NCT06072690
- Where
- Lithuania
- Volunteers
- 80 people
- Sponsor
- Lithuanian University of Health Sciences
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Postmenopausal, Menopausal Symptoms
Structured Combined Exercise Program in Postmenopausal Women: Effects on Heart Rate Variability and Menopausal Symptoms
The goal of this clinical trial is to learn whether a structured combined exercise program can improve heart health, menopausal symptoms, sleep quality, and quality of life in postmenopausal women aged 45 to 65 years.
- Conditions
- Postmenopausal, Menopausal Symptoms, Autonomic Nervous System Diseases, Sleep Wake Disorders
- Trial name
- NCT07615790
- Testing
- Structured Combined Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Fenerbahce University
Functional Voice Disorder, Psychogenic Voice Disorder
Autonomic Dysfunction in Functional Dysphonia
The first objective of this research project is to compare the occurrence and frequency of symptoms and/or disorders related to autonomic dysfunction in patients with functional dysphonia with gender- and age-matched vocally…
- Conditions
- Functional Voice Disorder, Psychogenic Voice Disorder, Muscle Tension Dysphonia
- Trial name
- NCT06100601
- Testing
- ANS regulation therapy, conventional voice therapy (CVT), ANS regulation therapy + CVT
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Ghent
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Bradycardia, Syncope, Vasovagal
Comparison of Focal Cryoablation vs. Radiofrequency Cardioneuroablation for Bradyarrhythmias
Bradyarrhythmias are conditions where the heart beats too slowly, causing symptoms like dizziness, fainting, and fatigue. In some patients, these slow heart rhythms are caused by overactivity of the vagus nerve (the part of the…
- Conditions
- Bradycardia, Syncope, Vasovagal, Sick Sinus Syndrome, Atrioventricular Block
- Trial name
- CRYO-CNA vs RF (NCT07671898)
- Testing
- Focal Cryoablation, Radiofrequency Catheter Ablation
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Type 1 Diabetes Mellitus
Hypoglycemia Fear Affect Autonomic Function, Physical Activity, and Exercise Capacity in Type I Diabetes
This cross-sectional study aims to investigate whether fear of hypoglycemia affects autonomic function, physical activity levels, and exercise capacity in children and adolescents with T1DM.
- Trial name
- HypoFear-T1DM (NCT07527676)
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Ordu University
Atrioventricular Block
Pacemaker Implantation Versus Cardioneuroablation for Functional Atrioventricular Block
The TELE-SPACER study is a multicenter, noncommercial, physician-initiated, proof-of-concept, prospective, randomized, controlled, unblinded clinical trial and registry designed to compare two methods of treatment of patients…
- Trial name
- TELE-SPACER (NCT05774262)
- Testing
- Pacemaker implantation, Cardioneuroablation (CNA)
- Where
- 2 sites in Poland
- Volunteers
- 300 people
- Sponsor
- American Heart of Poland
Parkinson Disease
Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male Parkinson's Disease Patients With Hypovitaminosis D
The goal of this clinical trial is to see the effect of vitamin D3 supplementation on cardiac autonomic nerve function in male Parkinson's disease patients with hypovitaminosis D Main questions it aims to answer are: 1.
- Trial name
- NCT07084597
- Testing
- Vitamin D
- Where
- Bangladesh
- Volunteers
- 15 people
- Sponsor
- Bangladesh Medical University
Posttraumatic Stress Disorder (PTSD), Depression - Major Depressive Disorder
To Investigate the Change of Brain and Autonomic Function From Different Protocols of Repeated Transcranial Magnetic Stimulation Therapy for Patients With Post-traumatic Stress Disorder Comorbid Major Depressive Disorder
This study aims to investigate the immediate neurophysiological and autonomic effects of two noninvasive brain stimulation protocols-prolonged intermittent theta-burst stimulation (prolonged iTBS) and high-frequency repetitive…
- Trial name
- NCT07327385
- Testing
- Prolonged Intermittent Theta-Burst Stimulation (prolonged iTBS), High-Frequency Repetitive Transcranial Magnetic Stimulation (HF-rTMS)
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Tri-Service General Hospital (TSGH)