Clinical trials: Cardiac Bypass Patients
Cardiac Surgery
A Registry Study on Serumal Biomarkers About Adverse Events in Patients Undergoing Coronary Artery Bypass Grafting.
This is a national registry study to determine the serumal biomarkers for prognosis of adverse events in patients undergoing coronary artery bypass grafting.
- Trial name
- ASBA-CABG (NCT04107571)
- Testing
- A type of operation for coranary heart disease patients.
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Postoperative Cognitive Dysfunction
The Effect on Cerebral Oxygenation of Retrograde Autologous Priming of the Cardiopulmonary Bypass Circuit in Cardiac Surgery Patients
The effect of retrograde autologous priming (RAP) on regional cerebral oxygenation (rSO2) still remains unclear, because studies are limited in sample size and study design, and because of the absence of prospective studies.
- Trial name
- RAP (NCT02108093)
- Testing
- retrograde autologous priming
- Where
- Netherlands
- Volunteers
- 220 people
- Sponsor
- Amphia Hospital
Coronary Artery Disease, Postoperative Care
CABG-AI-Supported Discharge Education
This randomized controlled trial will evaluate the effectiveness of artificial intelligence-supported individualized discharge education for patients undergoing coronary artery bypass graft (CABG) surgery.
- Conditions
- Coronary Artery Disease, Postoperative Care, Patient Discharge, Recovery of Function
- Trial name
- AI-D-E-CABG (NCT07503678)
- Testing
- AI-Supported Individualized Discharge Education, Standard Discharge Education
- Volunteers
- 128 people
- Sponsor
- Hasan Kalyoncu University
Cardiac Surgery With Cardiopulmonary Bypass, Complete Serum Phosphorus Measure
Serum Phosphatemia Predictive Marker for AKI Diagnosis After Cardiac Surgery
Cardiac surgery associated acute kidney injury is an independent factor of morbidity and mortality . Despite its delayed elevation, serum creatinine (Cr) remains the goal standard to diagnose AKI.
- Conditions
- Cardiac Surgery With Cardiopulmonary Bypass, Complete Serum Phosphorus Measure, Complete Serum Creatinine Measure
- Trial name
- PhosphoIRA (NCT02900313)
- Testing
- cardiac surgery
- Where
- France
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Post-discharge Outcomes
Retrospective Observational Study of Patients Who Have Undergone Coronary Artery Bypass Graft (CABG) and/or Cardiac Valve Surgery
This study is a retrospective chart abstraction for subjects who were enrolled in REN-004. As a retrospective study, all data will be abstracted from the medical records.
- Trial name
- NCT07009340
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Renibus Therapeutics, Inc.
Coronary Artery Disease
The HYCORE1 Trial: Hybrid Revascularization Versus Coronary Artery Bypass Grafting
Coronary artery disease often necessitates complex interventions like coronary artery bypass surgery (CABG) or percutaneous coronary intervention (PCI) with stents.
- Trial name
- HYCORE1 (NCT05504031)
- Testing
- Hybrid coronary revascularization, Conventional revascularization
- Where
- 3 sites in Belgium, Denmark and 1 more
- Volunteers
- 1,048 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Coronary Artery Bypass Grafting, Medication Adherence
Quality Measurement and Improvement Study of Surgical Coronary Revascularization: Medication Adherence
The study is a randomized controlled trial, having a plan to recruit 1000 patients underwent coronary artery bypass grafting in 1 of 5 participating sites in 2015, and randomized to either the intervention group or control group…
- Conditions
- Coronary Artery Bypass Grafting, Medication Adherence, Mobile Applications
- Trial name
- MISSION-2 (NCT02432469)
- Testing
- APP intervention
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- China National Center for Cardiovascular Diseases
Music Therapy, Pain
The Effect of Music Therapy on Pain and Anxiety in Patients After Coronary Artery Bypass Grafting
Coronary artery disease is a frequently occurring, life-threatening disease that has caused high morbidity and mortality, and has resulted in a high rate of death, both in our country and worldwide over the past five years.
- Conditions
- Music Therapy, Pain, Anxiety, Randomised Controlled Trial
- Trial name
- NCT07255339
- Testing
- Music therapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- University of Gaziantep
Coronary Artery Disease, Aspirin Resistance
Dual Antiplatelet Therapy in Patients With Aspirin Resistance Following Coronary Artery Bypass Grafting
Reactive platelet hyperactivity following coronary artery bypass grafting (CABG) might lead to thrombotic complications and major ischemic cardiac events.
- Trial name
- NCT01159639
- Testing
- Clopidogrel
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- University of Zagreb
Coronary Artery Disease
MIDCAB Versus DES in Proximal LAD Lesions
Percutaneous coronary intervention with a sirolimus-coated stent compared to minimally invasive bypass surgery in patients with isolated proximal left anterior descending coronary arteries in terms of non-inferiority of an end…
- Trial name
- NCT00299429
- Testing
- Stenting and minimally invasive bypass surgery, PCI with DES
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- University of Leipzig
Coronary Heart Disease
Efficacy and Safety of Hypertonic Sodium Lactate Solution Compared With 6% HES Solution in CABG Patients
The choice of fluid therapy is controversial in cardiac surgery. Numerous studies have shown that colloid is better as compared to crystalloids.
- Trial name
- NCT01654653
- Testing
- Hypertonic sodium lactate, 6% Hydroxy Ethyl Starch
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Innogene Kalbiotech Pte. Ltd
Postoperative; Dysfunction Following Cardiac Surgery
Impact of Mobilization on Cardiac Surgery
The objective of this study is to investigate the effects of a program of early mobilization in the functional capacity in patients undergoing coronary artery bypass grafting in short and long- term.
- Trial name
- NCT02312648
- Testing
- Interventional Group, Control group
- Volunteers
- 52 people
- Sponsor
- Luciana Chiavegato
Ischaemic Heart Disease
Trial of Rehabilitation in Phase 1 After Coronary Artery Bypass Grafting
Patients undergoing coronary artery bypass graft surgery often experience a range of problems and symptoms related to the procedure and the underlying heart disease.
- Trial name
- SheppHeart (NCT01941355)
- Testing
- Exercise training component, Psycho-educative component
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cardiac Surgery Intensive Care Treatment
Identification of Dominate Stressors in the Intensive Care Unit (ICU)
Undergoing cardiopulmonary bypass surgery and the subsequent admission to the intensive care unit (ICU) is known to be a stressful event to the patient.
- Trial name
- NCT00645008
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Weill Medical College of Cornell University
Ventricular Septal Defect
Bypass Clear Priming VSD Cardiopulmonary Bypass Circuit Reduce Bypass Associated Inflammation?
The purpose of this trial is to study if priming the pump used during cardiac surgery with non-blood fluids instead of donated blood products reduces the inflammation that occurs after heart surgery.
- Trial name
- NCT07393243
- Testing
- Clear priming of the bypass pump
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Seattle Children's Hospital
Anesthesia, Regional, Pain, Postoperative
Pectoral-Intercostal Fascial Plane Block Study
Pain along the sternum following opening of the chest cavity, also known as post-sternotomy pain (PSP), is a common complication after heart surgery that is associated with several negative side effects.
- Trial name
- PIFB (NCT03729635)
- Testing
- Pectoral-intercostal fascial plane block (PIFB)
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Coronary Artery Disease, Mitral Valve Insufficiency
Mitral Valve Repair Combined Coronary Artery Bypass Grafting(CABG) Verus CABG Alone on Functional Ischemic Mitral Regurgitation
Coronary artery bypass grafting(CABG) is an effective procedure in treating severe coronary artery disease(CAD). Optimal surgical method for CAD patients with functional ischemic mitral regurgitation(FIMR) is still controversial.
- Trial name
- NCT03525041
- Testing
- CABG, mitral valve annuloplasty
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Anzhen Hospital
Heart Valve Diseases, Image
Research on Neurological Prognosis of Patients Undergoing Heart Valve Surgery
The purpose of this study is to clarify the changes of neurocognitive function of patients undergoing cardiac valve disease before and after surgical treatment under cardiopulmonary bypass operation, and to predict the…
- Trial name
- NCT05539261
- Testing
- magnetic resonance image, Neuropsychological scale
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nanjing University of Traditional Chinese Medicine
Cardiac Surgery
Efficacy and Safety of Sodium Heparin (Hipolabor) in Patients
The objective of this study is to verify, through a randomized, single-blind, multicentre, parallel and comparative study, the effectiveness of heparin sodium of porcine origin in patients undergoing heart surgery at that require…
- Trial name
- HEPSBCCV0109 (NCT00894673)
- Testing
- Heparin sodium Hipolabor, Heparin sodium APP
- Where
- 2 sites in Brazil
- Volunteers
- 104 people
- Sponsor
- Azidus Brasil
Kidney Injury
Advance Targeted Transfusion in Anemic Cardiac Surgical Patients for Kidney Protection: A Proof of Concept Pilot Study
One of the major complications of heart surgery is kidney injury, which occurs in up to 30% of patients and is associated with poor outcomes including death.
- Trial name
- NCT00861822
- Testing
- Advanced red blood cell transfusion
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto