Clinical trials: Cardiac Bypass Patients
Cardiac Surgery and Cardiopulmonary Bypass
Sodium Bicarbonate in Cardiac Surgery
Many patients develop kidney failure after cardiac surgery. Although this kidney failure can usually be treated effectively, a longer stay in intensive care is often required.
- Trial name
- NCT00334191
- Testing
- Sodium Bicarbonate
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- Austin Health
Minimally Invasive Cardiac Surgery
The Quality of Life and Patency Rate After Minimally Invasive Cardiac Surgery
This trial will address essential questions of the efficacy and safety of MICS-CABG in addition to the quality of life and patency rate of the grafts.
- Trial name
- NCT05104320
- Testing
- MICS-CABG, sternotomy CABG
- Volunteers
- 248 people
- Sponsor
- Peking University Third Hospital
Anxiety, Depression
HINCAB-study. Home Based Intervention in Nursing for Coronary Artery Bypass Patients
HINCAB-study is a single senter, prospective, randomised controlled trial. The aim of the study is to test the effect of a home based intervention program.
- Trial name
- NCT00245817
- Testing
- HINCAB
- Where
- Norway
- Volunteers
- 203 people
- Sponsor
- Ullevaal University Hospital
Coronary Artery Disease
Efficacy of Early Short-term Training on Thrombogenesis in Patients Following Coronary Bypass Surgery
Although the benefit of cardiac rehabilitation following coronary artery bypass graft (CABG) is well-established, it is underused.
- Trial name
- NCT02144480
- Testing
- Intensive training, traditional training
- Where
- Taiwan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Coronary Artery Disease
Optimizing Timing of CABG in Patients Presenting With ACS and Treated With Ticagrelor
The administration of Ticagrelor have demonstrated superiority to Clopidogrel in patients presenting with acute coronary syndrome (ACS) and remains a first line therapy as an adjunct to aspirin for patients admitted with ACS.
- Trial name
- CABG-TIME (NCT02627521)
- Testing
- PRU guided CABG, CABG per standard of care, VerifyNow assay
- Where
- Canada
- Volunteers
- 260 people
- Sponsor
- Unity Health Toronto
Platelets, Bleeding
Delayed Cold-Stored Platelets -PLTS-1
PLTS-1 is a multicentre, randomized, controlled, pilot trial, using a conventional, parallel group, two-armed design at 2 cardiac surgery centres in Canada.
- Conditions
- Platelets, Bleeding, Cardiopulmonary Bypass, Cardiac Surgery
- Trial name
- PLTS-1 (NCT06147531)
- Testing
- Delayed Cold-Stored Buffy Coat Platelets, Room Temperature Buffy Coat Platelets
- Where
- 2 sites in Canada
- Volunteers
- 150 people
- Sponsor
- University Health Network, Toronto
Coronary Artery Disease, Atrial Fibrillation
Postoperative Lactate and Atrial Fibrillation After CABG
Postoperative atrial fibrillation (POAF) is associated with increased mortality and morbidity in patients undergoing isolated coronary artery bypass grafting (CABG).
- Trial name
- NCT05448521
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Delirium
Delirium and EuroSCORE II in Cardiac Surgery
The goal of this observational study is to find out the association between EuroSCORE II of Delirium in patients undergoing cardiac surgery.
- Trial name
- NCT05218720
- Testing
- EuroSCORE II risk score and CAM-ICU (The Confusion Assessment Method for the Intensive Care Unit)
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Aga Khan University
Cardiac Surgery, Cardiopulmonary Bypass
Voluven® in Paediatric Patients
This study will compare the clinical efficacy and safety of Voluven® and Human Albumin during elective open-heart surgery in pediatric patients.
- Trial name
- NCT00860405
- Testing
- HES 130/0.4 (6%) in sodium chloride (Voluven®, solution for infusion), Human serum albumin (HSA 50g/L), Human serum albumin (HSA 50g/L)
- Where
- 2 sites in Austria, Belgium
- Volunteers
- 61 people
- Sponsor
- Fresenius Kabi
Cardiac Surgical Procedures, Cardiac Surgical Procedures (Postoperative Population)
Vasoactive Inotropic Score in Adult Cardiac Surgery Outcomes
This study looked at whether a bedside score called the Vasoactive Inotropic Score (VIS) could help doctors predict which adult patients are at higher risk of complications after heart surgery that uses a heart-lung machine…
- Trial name
- NCT07745283
- Where
- India
- Volunteers
- 635 people
- Sponsor
- Sir Ganga Ram Hospital
Coronary Artery Disease, Stroke
Effects of Left Atrial Appendage Resection and Marshall Ligament Amputation on Clinical Outcome in Patients Undergoing Off-pump Coronary Artery Bypass
Surgical occlusion of the left atrial appendage (LAAO) is sometimes performed during the cardiac surgery to reduce long-term risk of stroke.A previous study found that LAAO may be associated with increased risk of postoperative…
- Conditions
- Coronary Artery Disease, Stroke, Atrial Fibrillation
- Trial name
- NCT04220047
- Testing
- Left Atrial Appendage Resection and Marshall Ligament Amputation
- Where
- China
- Volunteers
- 400 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Disease, Anesthesia
Xenon in Off-pump Coronary Artery Bypass Graft Surgery
Purpose of this study is to test whether xenon application during off-pump-coronary artery bypass (OPCAB)-surgery is safe and feasible.
- Trial name
- NCT01757106
- Testing
- Xenon, sevoflurane
- Where
- Belgium
- Volunteers
- 42 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ischemic Heart Disease
Long-term Outcomes and Prognostic Factors in Patient Undergoing CABG or PCI
1. To evaluate the long-term clinical outcomes and prognostic factors in patients with coronary artery disease undergoing coronary artery bypass graft surgery. 2.
- Trial name
- NCT03870815
- Testing
- CABG, PCI
- Where
- South Korea
- Volunteers
- 10,000 people
- Sponsor
- Samsung Medical Center
Coronary Artery Occlusion
Effects of N-acetylcysteine on Pulmonary Function in High-risk Patients Undergoing Off-pump Coronary Bypass Surgery
The purpose of this study is to study the effects of N-acetylcysteine on pulmonary function in high-risk patients undergoing off-pump coronary bypass surgery.
- Trial name
- NCT01021163
- Testing
- N-acetylcysteine, saline
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Atrial Fibrillation
Effect of Venous Cannulation on the Incidence of Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass
Context Atrial fibrillation is the most frequent arrhythmia following coronary artery bypass grafting. POAF is associated with worse outcomes following CABG.
- Trial name
- NCT04641611
- Testing
- Bicaval cannulation, Cavoatrial cannulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Dr. Jean-Francois Morin
Cardiac Surgery Requiring Cardiopulmonary Bypass, Brain Injury
The Association Between Tau & GFAP and Postoperative Neurological Impairment in Patients Undergoing Cardiac Surgery
Patients born with heart defects often undergo surgical procedures on a heart lung machine. With improvements in medical and surgical management, their survival has significantly improved, but their brain insult has not been paid…
- Conditions
- Cardiac Surgery Requiring Cardiopulmonary Bypass, Brain Injury, Congenital Heart Defect
- Trial name
- NCT06899971
- Testing
- Collecting discarded blood samples
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Systemic Inflammatory Response, Aortic Valve Stenosis
Evaluation of Intraoperative Dexmedetomidine Use in Patients Undergoing Surgical Aortic Valve Replacement
Aim of this randomized prospective study is to investigate the immunomodulatory effects of dexmedetomidine on outcomes in patients with isolated aortic stenosis after surgical aortic valve replacement.
- Trial name
- NCT05641064
- Testing
- Dexmedetomidine 0.5mcg/kg/h, Dexmedetomidine 1 mcg/kg/h
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital Dubrava
Postoperative Delirium
Intraoperative Dexmedetomidine Use, MMP-8, and Postoperative Delirium After Cardiac Surgery With Cardiopulmonary Bypass
This observational study evaluated the association between intraoperative dexmedetomidine use and postoperative delirium (POD) in adults undergoing cardiac surgery with cardiopulmonary bypass (CPB).
- Trial name
- NCT07759297
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 5,688 people
- Sponsor
- Shusheng Li
Vascular Occlusion Test
Near-Infrared Spectroscopic (NIRS) Tissue Oxygen Saturation and the Vascular Occlusion Test in Cardiac Surgery Patients
Tissue oxygen saturation (StO2) and its recovery during a vascular occlusion test (VOT) will be measured in elective cardiac surgery patients undergoing cardiopulmonary bypass using a non-invasive near infrared spectrometry…
- Trial name
- NCT01712750
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- London Health Sciences Centre
Telehealth, Coronary Artery Bypass Surgery
The Effectiveness of a Telehealth Program on Cardiac Symptom Distress, Self-care and Quality of Life of Patients With Coronary Artery Disease After Coronary Artery Bypass Surgery: A Randomized Study
The goal of this randomized trial is to compare the outcomes of a telehealth program with conventional discharge care for patients aged 18 years and older with coronary artery disease following coronary artery bypass surgery.
- Trial name
- NCT06648291
- Testing
- QOCA EKG Device, Usual Care
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital