Clinical trials: Cardiac Catheterisation
Portopulmonary Hypertension
Ambrisentan in Patients With Porto-pulmonary Hypertension A Multicenter Open Label Trial
This is an Open Label, Multicenter, pilot clinical trial to assess the efficacy and safety of an oral selective Endothelin Receptor Antagonist (ambrisentan) in patients with portopulmonary hypertension.
- Trial name
- Portopulm (NCT01224210)
- Testing
- Ambrisentan
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- Tufts Medical Center
Coronary Angiography, Coronary Angioplasty
DIstal vs Proximal Radial Artery Access for Cath
This single-center, prospective, randomized study will evaluate distal radial artery (dRA) vs. proximal radial artery access (pRA) in regards to hand function and radial artery occlusion.
- Trial name
- DIPRA (NCT04318990)
- Testing
- Distal radial artery access, Proximal radial artery surgery
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Baylor Research Institute
Acute Myocardial Infarction
ClearWay Rx Readmission Registry
The purpose of this registry is to determine if delivery of weight adjusted, in a large dose with either Abcixmab or Eptifibitide through the ClearWay™ RX, in patients admitted for primary coronary intervention lowers readmission…
- Trial name
- ClearWay (NCT01673893)
- Testing
- ClearWay™ Rx catheter
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Cardiovascular Institute of the South Clinical Research Corporation
Preprocedure Anxiety
Impact of Virtual Reality on Pre-procedural anxieTy Prior to Heart cathEterIzAtion - VR-THEIA
The primary aim of this study is to test the hypothesis that use of VR combined with standard procedural education will result in less pre-procedural anxiety than standard procedural education alone among patients undergoing…
- Trial name
- VR-THEIA (NCT03662607)
- Testing
- Virtual reality experience
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Corewell Health West
Foramen Ovale, Patent, Heart Catheterization
Procedural Success and Safety of the Nit-Occlud® Patent Foramen Ovale (PFO) Closure Device and Its Application System
The foramen ovale is an opening in the interatrial septum. It results from an incomplete coverage of the ostium secundum. In 10 to 24% of the general population incomplete fibrosis of the interatrial septum is a clinical finding…
- Conditions
- Foramen Ovale, Patent, Heart Catheterization, Heart Septal Defects, Atrial
- Trial name
- 09k003 (NCT00968032)
- Testing
- Nit-Occlud® PFO
- Where
- Germany
- Volunteers
- 63 people
- Sponsor
- pfm medical gmbh
Coronary Artery Disease
Simultaneous Assessment of FFR and SPECT
The overall purpose of this research study is to identify the disparity in ischemia measurement between fractional flow reserve (FFR) used in the cardiac catheterization laboratory and myocardial perfusion stress- single-photon…
- Trial name
- NCT02749045
- Testing
- SPECT imaging
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Prem Soman
Heart Catheterization
Randomized, Open Label Study of Dabigatran Etexilate in Elective Percutaneous Coronary Intervention
To assess whether two doses of dabigatran etexilate (110 mg twice daily (b.i.d) and 150 mg twice daily (b.i.d)) as compared to unfractionated heparin (UFH), both in addition to a standard dual antiplatelet regimen, provide…
- Trial name
- NCT00818753
- Testing
- dabigatran 110 mg, dabigatran 150 mg, unfractionated heparin
- Where
- 4 sites in Netherlands
- Volunteers
- 53 people
- Sponsor
- Boehringer Ingelheim
Pulmonary Hypertension
Evaluate Effect of Optison on Pulmonary Artery Systolic Pressure (PASP) and Pulmonary Vascular Resistance (PVR).
The design of this study is to conduct a comprehensive safety evaluation of the pulmonary hemodynamic effects of Optison. The study is being conducted in subjects referred for cardiac catheterization for clinical reasons.
- Trial name
- NCT00878878
- Testing
- Optison (Perflutren Protein-Type A Microspheres Injectable Suspension), Dextrose
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- GE Healthcare
Radiation Exposure to Operator
Physician Radiation Exposure During Radial Access Cardiac Catheterization Using a RAD Board
Radiation exposure to operator is an occupational hazard of invasive cardiologists. During radial access for diagnostic catheterization, a new radio-dense arm board is advertised to reduce operator radiation exposure.
- Trial name
- NCT02088788
- Testing
- Board, No Board
- Where
- United States
- Volunteers
- 265 people
- Sponsor
- Geisinger Clinic
Accidental Puncture of Artery During Catheter Insertion
Ultrasound Guided Technique for Internal Jugular Central Venous Catheterization in Pediatric Cardiac Surgical Patients
The purpose of the study is to evaluate the success rate using ultrasound as guidance during central venous cannulation in pediatric cardiac surgical patients.
- Trial name
- NCT02687126
- Testing
- Central Venous Catheterization
- Where
- Nepal
- Volunteers
- 106 people
- Sponsor
- Shahid Gangalal National Heart Centre
Hypertension, Congestive Cardiomyopathy
The Acute Effects of the Angiotensin-converting Enzyme Inhibitor Enalaprilat on Flow Distribution
The primary objective of this study is to study the acute effects of angiotensin-converting enzyme inhibitor (ACEI) on systemic, pulmonary and cerebral blood flow in post bidirectional cavopulmonary connection (BCPC) patients.
- Trial name
- NCT00741156
- Testing
- Enalaprilat
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- The Hospital for Sick Children
Coarctation of the Aorta
Coarctation Of the Aorta Stent Trial
The purpose of this study is to determine whether Cheatham Platinum bare metal stents are safe and effective in the treatment of native and recurrent aortic coarctation in selected children, adolescents and adults.
- Trial name
- COAST (NCT00552812)
- Testing
- Stent therapy of aortic coarctation
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Richard E. Ringel
Coronary Artery Disease
Intravenous Regadenoson Versus Intravenous Adenoscan® for Fractional Flow Reserve (FFR)
The purpose of this study is to demonstrate that intravenous regadenoson is equivalent to intravenous Adenoscan® for the physiological assessment of intermediate coronary lesions.
- Trial name
- NCT01482169
- Testing
- FFR Measurement with IV Adenoscan® then with Regadenoson
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Ochsner Health System
Myocardial Infarction, Coronary Artery Disease
PET/CT Study in the Diagnosis of Coronary Plaque
This study is being done to determine if a picture taking test of the heart, positron emission tomography/computed tomography (or cardiac PET/CT), can identify the blockages in the heart arteries that lead to heart attacks when…
- Conditions
- Myocardial Infarction, Coronary Artery Disease, Cardiac Catheterization
- Trial name
- PET/CT (NCT00850473)
- Testing
- PET/CT
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Washington University School of Medicine
Anterior Wall Acute Myocardial Infarction
Evaluation of the Delivery of Optimized Supersaturated Oxygen Therapy to Treat Patients With an Acute Heart Attack
The purpose of this study is to evaluate the feasibility of the delivery of SuperSaturated Oxygen (SSO2) Therapy for 60 minutes selectively into the left main coronary artery (LMCA).
- Trial name
- NCT01630707
- Testing
- SuperSaturated Oxygen (SS02) Therapy
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- TherOx
Renal Artery Stenosis
Prevalence of Renal Artery Stenosis in Patients Referred for Cardiac Catheterization
All patients referred for coronary angiography will simultaneously be evaluated for renal artery stenosis and then stenosis more than 50% will be analyzed according to clinical conditions, risk factors and lab data.
- Trial name
- RAS (NCT00885768)
- Testing
- angiography
- Where
- Iran
- Volunteers
- 146 people
- Sponsor
- Imam Khomeini Hospital
Cardiac Catheterization, Spasm
Topical Radial Artery Vasodilation
The aim of the study is to facilitate radial artery access for cardiac catheterization. The investigators hypothesize that topical nitroglycerin and lidocaine will reduce radial artery spasm.
- Trial name
- NCT01155167
- Testing
- Nitroglycerin and lidocaine
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of California, San Francisco
Coronary Artery Disease, Chest Pain
The Effect of Clopidogrel on Coated-Platelets in Patients Undergoing Cardiac Catheterization
This study will explore the effect of clopidogrel on coated-platelets in patients who are given a loading dose before diagnostic catheterization or percutaneous coronary intervention.
- Trial name
- NCT00644657
- Testing
- Clopidogrel
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Oklahoma
Chronic Renal Insufficiency, Diabete Mellitus
Safety Study of GE-145 320 mg I/mL Injection vs. Iopamidol 370 mg I/mL in Elderly Subjects Undergoing Coronary Procedure
To evaluate cardio-renal and overall safety profile of GE 145 320 mg I/ml Injection when compared to iopamidol 370 mg I/mL. The study will focus on elderly subjects with either chronic renal insufficiency, or diabetes mellitus…
- Conditions
- Chronic Renal Insufficiency, Diabete Mellitus, Congestive Heart Failure
- Trial name
- NCT01252810
- Testing
- GE-145
- Where
- United States
- Volunteers
- 284 people
- Sponsor
- GE Healthcare
Angioplasty, Transluminal, Percutaneous Coronary, Coronary Arteriosclerosis
Safety and Effectiveness Study of the Ensure Medical Vascular Closure Device
The purpose of this study is to determine whether the Ensure Medical Vascular Closure Device is more effective than standard manual compression at sealing the puncture made in the femoral artery following a cardiac or peripheral…
- Conditions
- Angioplasty, Transluminal, Percutaneous Coronary, Coronary Arteriosclerosis, Peripheral Arteriosclerosis
- Trial name
- NCT00345631
- Testing
- Manual Compression, Vascular Closure Device
- Where
- 17 sites in United States
- Volunteers
- 488 people
- Sponsor
- Cordis US Corp.