Clinical trials: Cardiac Complications
Cardiac Valve Replacement Complication
Short Term Effect of Vitamin D Supplementation on the Clinical Outcomes in Patients Undergoing Valve Replacement Surgery
This study evaluates the effect of Vitamin D supplementation on ICU and hospital LOS in patients undergoing valve replacement surgery.
- Trial name
- NCT04085770
- Testing
- Alfacalcidol 1 MCG Oral Capsule
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Cairo University
Paresthesia, Peri-operative Injury
Paresthesia in Hand and Antebrachium Following CardiacSurgery: Incidence, Risk Factors and Clinical Course
To describe the incidence and severity of Paresthesia in Hand and Antebrachium in patients that have undergone CardiacSurgery.
- Conditions
- Paresthesia, Peri-operative Injury, Complication,Postoperative, Upper Limb Nerve Lesion
- Trial name
- NCT06088823
- Testing
- Heart surgery
- Where
- Denmark
- Volunteers
- 361 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Vascular Closure
Groin Complications Post Percutaneous Coronary Intervention Using Either Manual Compression or PERCLOSE Device
The objective of this study is to compare groin complication rates in low and high risk patients post percutaneous coronary intervention (PCI) closed by either a 6 French Perclose vascular closure device (VCD) or manual…
- Trial name
- NCT00842179
- Where
- United States
- Volunteers
- 2,517 people
- Sponsor
- Clinyx, LLC
Coronary Disease
Pro-calcitonin Marker as Indicator of Ischemia in Patients With Complicated Coronary Intervention.
The aim of this study is to determine on preliminary basis weather an elevated pro-calcitonin level can be used to assess ischemia as a result of coronary artery complications during percutaneous coronary intervention (PCI).
- Trial name
- NCT01609569
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Saint Michael's Medical Center
Diabetes, Cardiovascular Disease
Haptoglobin Phenotype and Cardiovascular Complications in Diabetic Patients
3054 diabetic patients were screened for Haptoglobin Phenotype as part of the ICARE study (NCT00220831) and composite the I CARE Registry, 1434 Hp 2-2 patients were treated as part of the I CARE study with vitamin E vs.
- Conditions
- Diabetes, Cardiovascular Disease, Myocardial Infarction
- Trial name
- ICARER (NCT00448487)
- Where
- Israel
- Volunteers
- 3,054 people
- Sponsor
- Dr. Shany Blum
Acute Kidney Injury
Preoperative Prediction of Acute Kidney Injury After Cardiac Surgery
Although acute kidney injury (AKI) frequently complicates cardiac surgery, methods to determine AKI risk are lacking. Renal functional reserve (RFR), the capacity of the intact nephron mass to increase glomerular filtration rate…
- Trial name
- RFR (NCT03092947)
- Testing
- No intervention
- Volunteers
- 110 people
- Sponsor
- University of Giessen
Gonadal Dysgenesis, Turner's Syndrome
Effect of Biosynthetic Growth Hormone and/or Ethinyl Estradiol on Adult Height in Patients With Turner Syndrome
Turners Syndrome is a genetic condition in females that is a result of abnormal chromosomes. Girls with Turner syndrome are very short as children and as adults.
- Trial name
- NCT00001221
- Testing
- Growth Hormone (Humatrope)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Anemia, Cardiovascular Complications
Prostate Adenocarcinoma TransCutaneous Hormones
RATIONALE: The increasingly prolonged and extended use of androgen deprivation therapy (ADT) in the treatment of prostate cancer, usually achieved through the administration of LHRH agonists, has raised concerns about long-term…
- Conditions
- Anemia, Cardiovascular Complications, Hot Flashes, Osteoporosis
- Trial name
- PATCH (NCT00303784)
- Testing
- Goserelin, Estradiol
- Where
- 32 sites in United Kingdom
- Volunteers
- 2,200 people
- Sponsor
- University College, London
Intracranial Embolism and Thrombosis, Postoperative Complications
TCD Detection of Gas and Solid Micro-Emboli in Patients Undergoing Coronary Artery Bypass Grafting (CABG): The Influence of Proximal Anastomosis Technique
The purpose of this study is to test the hypothesis that using three different techniques to anastomose coronary grafts to the aorta: partial occlusion, single cross clamp, or using the Heartstring anastomotic device, will change…
- Trial name
- NCT00294814
- Testing
- Proximal anastomosis using Heartstring anastomotic device
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Kidney Disease, Chronic
Study of Heart and Renal Protection
The chief aim of SHARP was to determine whether lowering blood LDL cholesterol with simvastatin (20mg) plus ezetimibe (10mg) daily could safely reduce the risk of coronary heart disease, non-hemorrhagic stroke and the need for…
- Trial name
- SHARP (NCT00125593)
- Testing
- Simvastatin 20 mg, Ezetimibe 10mg
- Where
- United Kingdom
- Volunteers
- 9,438 people
- Sponsor
- University of Oxford
Pain, Postoperative, Anesthesia
Oral Methadone in Cardiac Surgery
The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac…
- Conditions
- Pain, Postoperative, Anesthesia, Cardiac Surgery
- Trial name
- OMICS (NCT07221617)
- Testing
- Methadone, oral, Methadone, intravenously
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Chronic Dialysis in Children
Dietary Sodium Intake in Children on Chronic Dialysis
Cardiovascular disease is common in patients with end-stage renal disease that began in childhood, and volume overload plays a key role in the development of hypertension, left ventricular hypertrophy (LVH) and alterations.
- Trial name
- PeDialysis (NCT06165640)
- Where
- France
- Volunteers
- 4 people
- Sponsor
- University Hospital, Strasbourg, France
Cardiac Implantable Electronic Device Complications
Impact on Patient Outcome of Cardiac Implantable Electronic Device Complications
The purpose of this registry is to evaluate the impact on patient outcome and on healthcare utilization of cardiac implantation electronic device complications during a long-term follow-up.
- Trial name
- POINTED (NCT03612635)
- Testing
- Implantation of a cardiac implantable electronic device
- Where
- 6 sites in Italy
- Volunteers
- 2,811 people
- Sponsor
- Azienda Ospedaliera Cardinale G. Panico
Cardio-Renal Syndrome
Kidney Sodium Content in Cardiorenal Patients
Diuretic therapy is the cornerstone of the management of fluid overload in heart failure. Resistance to diuretic therapy is the most common reason for treatment failure in patients affected by the combination of heart failure and…
- Trial name
- NCT04170855
- Testing
- Furosemide Injection
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Complication of Surgical Procedure
Factors Responsible for the Effectiveness of the Lund De-airing Technique
The Lund de-airing technique is employed for cardiac de-airing in open left heart surgery. It consists of two main elements namely, opening of both pleura after the patient is on CPB (cardiopulmonary bypass)and disconnection of…
- Trial name
- NCT01757704
- Testing
- Open pleurae & conventional filling of heart, Intact pleurae & staged filling of heart
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Lund University
Acute Kidney Injury
Effect of Darbepoetin in Contrast-induced Nephropathy
The purpose of this study is to determine whether the drug that produce red blood cells is effective in the prevention of kidney dysfunction after coronary angiography in patients with chronic kidney disease.
- Trial name
- NCT01197235
- Testing
- darbepoetin-α, isotonic saline
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Bundang Hospital
Cognitive Dysfunction, Postoperative, Cognitive Dysfunction
Assessment of Brain Oxygen Drops During Surgery and Related Risk Factors for Cognitive Problems After Heart Surgery
This study examines whether decreases in brain oxygen levels during cardiac surgery are linked to postoperative cognitive dysfunction and identifies other factors that may increase the risk of cognitive impairment.
- Conditions
- Cognitive Dysfunction, Postoperative, Cognitive Dysfunction, Cardiac Surgery
- Trial name
- NCT07361068
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
ST Elevation Acute Myocardial Infarction
Cyclosporine and Prognosis in Acute Myocardial Infarction (MI) Patients
Infarct size is a major determinant of prognosis after Acute Myocardial Infarction (AMI). The investigators recently reported that cyclosporine A, when administered immediately prior to percutaneous coronary intervention (PCI)…
- Trial name
- CIRCUS (NCT01502774)
- Testing
- Injection of Cyclosporin, Echocardiography
- Where
- 45 sites in Belgium, France and 1 more
- Volunteers
- 970 people
- Sponsor
- Hospices Civils de Lyon
Postoperative Delirium, Postoperative Agitation
Emergence Agitation in Paediatric Day Care Surgery
Emergence agitation is a significant and persistent challenge in paediatric anaesthesia, especially in children of preschool age.
- Conditions
- Postoperative Delirium, Postoperative Agitation, Anesthesia, Pain Monitoring
- Trial name
- NCT06571890
- Testing
- Narcotrend bispectral index anaesthesia monitor, Mdoloris Anaesthesia Nociception Monitor
- Where
- Denmark
- Volunteers
- 93 people
- Sponsor
- University of Southern Denmark
Infarction, Myocardial
Comparaison of 2 SpO2 Level Measured by Pulse Oxymetry in Complications of Acute Coronary Syndrome.
During acute coronary syndrome, the American College of Cardiology and the American Heart Association recommend oxygen delivery to patients with less than 90% oxygen saturation.
- Trial name
- FreeO2 SCA (NCT03122210)
- Testing
- Automated oxygen administration
- Volunteers
- 60 people
- Sponsor
- Laval University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.