Clinical trials: Cardiac Conditions
Preterm, Patent Ductus Arteriosus
NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot
Non-invasive tools for monitoring of course of disease are important and necessary in the treatment of pre-term/premature infants and sick neonates.
- Conditions
- Preterm, Patent Ductus Arteriosus, Sepsis, Asphyxia
- Trial name
- CE-NeoDoppler (NCT06646250)
- Testing
- NeoDoppler - CE certified
- Where
- Norway
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Cardiac Output, Stroke Volume
Exercise Induced Plasma Volume Expansion Lowers Cardiovascular Strain
The goal of this observational study was to better understand the impact of increased plasma volume on later exercise in hypoxia. Investigators examined young, healthy, males who regularly participated in aerobic exercise.
- Trial name
- NCT05800808
- Testing
- High Intensity Intervals, Moderate Exercise
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- California Baptist University
Coronary Disease, Myocardial Infarction
Identification of the Blood Microbiota in Patient Suffering From Myocardial Infraction
The investigators want to compare blood microbiota profile between patients with documented coronary lesions and patients free of coronary disease.
- Trial name
- FLORINF (NCT02405468)
- Where
- France
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Cardiac Arrest, Emergencies
Intravascular Access of COVID-19 Patient Under Personal Protective Equipment
The current COVID-19 pandemic, this is especially since the transmission of SARS-CoV-2 is thought to occur mainly through respiratory droplets generated by coughing and sneezing, by direct contact with contaminated surfaces and…
- Trial name
- NCT04366297
- Testing
- Intravenous access, Intraosseous access
- Where
- Poland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Lazarski University
Autoimmune Diseases, Cardiovascular Disorders
Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
This multi-arm, multi-site study investigates the safety, tolerability, and efficacy of stem cell therapy for the treatment of various acute and chronic conditions.
- Conditions
- Autoimmune Diseases, Cardiovascular Disorders, Diabetes Complications, Integumentary Disease
- Trial name
- NCT04684602
- Testing
- PrimePro™/ PrimeMSK™
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Thomas Advanced Medical LLC
Limb Edema, Surgical Site Infections
Prevention of Edema After Coronary Artery Bypass Graft by Customized Pressure-guided Elastic Bandages
The study aimed to assess the efficacy of customized pressure-guided elastic bandages (CPG-EB) in preventing postoperative edema and complications in Coronary Artery Bypass Graft (CABG) patients.
- Conditions
- Limb Edema, Surgical Site Infections, Leg Swelling, Compression Bandages
- Trial name
- PEACCE (NCT06603961)
- Testing
- CPG-EB group
- Where
- 2 sites in Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Heart Failure, Hyperthermia
IEEM-Heat and Heart Failure
We will test the hypothesis that increasing skin wetness, and thus evaporative cooling, will attenuate the increase in core body temperature and accompanying cardiac stress during heat wave conditions in individuals with…
- Trial name
- NCT06961929
- Testing
- Control Trial, Water-saturated T-shirt trial, Skin-Wetting Trial
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Cardiac Arrest, Inflammation
Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)
This is a prospective, observational study to investigate molecular mechanisms mediating the systemic inflammatory process, and changes to metabolism, and their impact on brain injury, survival, and functional outcomes after…
- Conditions
- Cardiac Arrest, Inflammation, Obesity, Hypoxic Ischemic Encephalopathy (HIE)
- Trial name
- PCAS (NCT02664831)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- MaineHealth
Heart Diseases, Type2 Diabetes
Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico
The overall goal is to identify trends and longitudinal associations in psychosocial, food-related, and cardiometabolic risk factors that can guide public health priorities and future research needs aimed at reducing…
- Conditions
- Heart Diseases, Type2 Diabetes, Hypertension, Obesity
- Trial name
- PROSPECT (NCT03794531)
- Where
- Puerto Rico
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Orthostatic Intolerance
Effects of Age, Sex and Isometric Exercise on Ventricular-Vascular Interactions During Cardiac Unloading
As people get older, especially women, they often feel dizzy or even faint when they go from sitting or lying down to standing up.
- Trial name
- Unload heart (NCT06939153)
- Testing
- LBNP, LBNP + Isometric handgrip exercise
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Tracy Baynard
Shock
HEAVy HAT-HEAlthy Volunteers Heart to Arm Time. Haemorrhage Simulation Protocol in Healthy Volunteers
In prehospital settings, hypovolemic shock diagnosis is based on Advanced Trauma Life Support (ATLS) shock classification. The most often used clinical signs are heart rate (HR), arterial blood pressure (BP), respiratory rate…
- Trial name
- HEAvyHAT (NCT02177188)
- Testing
- LBNP Lower Bodi Negative Pressure Chamber
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Massage, Heart Failure
Effect of Massage Therapy on Fatigue and Sleep Quality in Patients With Heart Failure in Intensive Care Unit
The purpose of this study was to explore the effect of massage therapy on fatigue and sleep quality in patients with heart failure in the intensive care unit.
- Trial name
- NCT05366673
- Testing
- massage
- Where
- Taiwan
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Obesity, Pre-hypertension
The Effects of Stretching Training on Arterial Function and Autonomic Control
Hypertension is a major risk factor for cardiovascular disease. Hypertension and abdominal obesity are associated with dysfunction of the main mechanisms of cardiovascular regulation, the autonomic nervous system and the vascular…
- Conditions
- Obesity, Pre-hypertension, Hypertension
- Trial name
- NCT01741766
- Testing
- Stretching Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Florida State University
Myocardial Infarction
Statins and Risk of Myocardial Infarction in Real Life in France
The main objective of this case-referent study is to assess the impact of statins usage on the risk of having a first myocardial infarction (MI) in a real life situation in France
- Trial name
- NCT00679575
- Where
- 56 sites in France
- Volunteers
- 13,171 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Slow Breathing, Acute Myocardial Infarction
The Effect of Slow Breathing Exercise Applied to Patients on Pulse, Blood Pressure and Quality of Life
This study was designed as a randomized controlled experimental type in order to determine the effect of slow breathing exercise applied after the procedure on heart rate, blood pressure and quality of life in patients who…
- Trial name
- NCT06098222
- Testing
- Slow breathing exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Metallosis, Pain
Neurotoxicity and Cardiotoxicity in Total Joint Arthroplasty
The purpose of this research is to understand whether patients who previously had total hip or total knee replacement experience memory, thinking or heart problems.
- Conditions
- Metallosis, Pain, Total Hip Replacement, Total Knee Replacement
- Trial name
- NCT04166539
- Testing
- Questionnaires, Interviews, Blood draw
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Atrial Fibrillation
Electrocardiogram Clinical Validation Study
The purpose of the study is to confirm the Garmin ECG (electrocardiogram) software algorithm can detect and classify atrial fibrillation and normal sinus rhythm on single lead ECG data derived from a Garmin wrist-worn, consumer…
- Trial name
- NCT04842123
- Testing
- Electrocardiogram
- Where
- 6 sites in United States
- Volunteers
- 568 people, healthy volunteers welcome
- Sponsor
- Garmin International
Heart Rate Fast, Blood Pressure
Short-term Effects of Passiflora and Meditation on Blood Pressure and Heart Rate
This study is intended to study the effects of one-time acute dosing of a solid extract of Passiflora incarnata, also known as Passionflower, on blood pressure and heart rate in students.
- Trial name
- NCT03953469
- Testing
- Passiflora incarnata
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Bridgeport
Apnea
A Study of Breathing Sound-based Classification of Patients With Breathing Disorders
Sleep-disordered breathing can damage the cardiovascular system, and may also lead to dysregulation of the autonomic nervous system, endocrine disorders, and hemodynamic changes, causing multi-system and multi-organ damage.
- Trial name
- NCT05868694
- Testing
- polysomnography
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Huai'an No.1 People's Hospital
Obesity, Heart Disease
Helping People to Exercise Regularly
This study tests two different incentive mechanisms to induce members of a particular urban senior center to attend more exercise classes.
- Trial name
- NCT01335880
- Testing
- Coupons for use within the next week, Coupons for use within the next 3 months
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
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