Clinical trials: Cardiac Electrophysiology
Atrial Flutter
Cardiac Electrophysiological Study
The purpose of the study is to measure the effects of AZD1305 on cardiac electrophysiological properties and intracardiac pressures
- Trial name
- NCT00616629
- Testing
- AZD1305
- Where
- 13 sites in Denmark, Finland and 2 more
- Volunteers
- 55 people
- Sponsor
- AstraZeneca
Subarachnoid Hemorrhage
Study to Evaluate Esmolol (Brevibloc) to Manage Cardiac Function in Patients With Subarachnoid Hemorrhage
The purpose of this study is to evaluate the clinical effect of esmolol treatment on cardiac function and electrophysiology; to assess the effects of esmolol treatment on serum adrenergic and cardiac biomarkers; to explore the…
- Trial name
- ABASH (NCT01232400)
- Testing
- Esmolol
- Where
- United States
- Sponsor
- University of Michigan
Atrial Fibrillation, Atrial Flutter
Anatomical Navigation for Guided Electrophysiology in AFL and AFib
The objective of the study is to collect data on the use of the VERAFEYE Anatomical Guidance System in adult patients indicated to undergo a catheter ablation procedure for the treatment of Atrial Flutter (AFL), paroxysmal AF…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Atrial Arrhythmia
- Trial name
- ANGEL-AF (NCT07210151)
- Testing
- VERAFEYE Anatomic Guidance System
- Where
- 4 sites in Croatia, Czechia and 1 more
- Volunteers
- 50 people
- Sponsor
- LUMA Vision Ltd.
Periodontitis, Cardiac Electrophysiology
Effects of Periodontitis on Heart Rate Variability
Periodontitis is a chronic inflammatory disease associated with systemic inflammatory burden and possible alterations in autonomic nervous system regulation.
- Trial name
- NCT07735312
- Testing
- Non-surgical periodontal therapy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cardiac Disease
Anesthetic Techniques in EP Patients
The purpose of this study is to compare different combinations of anesthetic drugs (cause loss of sensation) in terms of effectiveness, adverse effects, pain relief, and patient comfort for cardiac electrophysiology procedures.
- Trial name
- NCT02664922
- Testing
- Propofol, Ketamine, Remifentanil
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of California, Los Angeles
Cardiac Electrophysiology
Study to Evaluate Tetanizing Burst Therapy in Patients Undergoing ICD Replacement
This study evaluates whether the addition of tetanizing burst therapy reduces the pain associated with ICD shocks
- Trial name
- NCT03628911
- Testing
- Tetanizing Burst Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- EP Sciences
Arrythmia
Epicardial Access Study With Rook
The goal of this clinical trial is to test how how effective the Circa Scientific Rook® Epicardial Access Kit is at gaining guidewire access to the outside surface of the heart (epicardium).
- Trial name
- EASY-R (NCT06388629)
- Testing
- Rook Epicardial Access Kit
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Circa Scientific, Inc.
Ventricular Tachycardia
Modification of the Local Abnormal Ventricular Activity Only
Local abnormal ventricular activity (LAVA) is composed of high-frequency, mainly low voltage signals that represent near-field signals from slow-conducting tissue and thus potential VT isthmuses.
- Trial name
- LAVAONLY (NCT05331716)
- Testing
- Cardiac ablation therapy
- Where
- Germany
- Volunteers
- 22 people
- Sponsor
- University of Kiel
Ventricular Tachycardia, Coronary Artery Disease
Trial Comparing Ablation With Medical Therapy in Patients With Ventricular Tachycardia
This study aims to compare antiarrhythmic drug therapy with catheter ablation using the SmartTOUCH catheter (Biosense Webster Inc.) as treatment for patients with ventricular tachycardia and coronary artery disease
- Trial name
- VeTAMed (NCT01798277)
- Testing
- Catheter Ablation, Medical therapy (sotalol or amiodarone)
- Sponsor
- Newmarket Electrophysiology Research Group Inc
Cardiac Arrhythmia
Hemodynamics Measurement in Radiofrequency Catheter Ablation
This study will occur in patients undergoing routine cardiac ablation of his/her arrhythmia with planned use of an irrigated ablation catheter.
- Trial name
- NCT04227119
- Testing
- Irrigated ablation catheter, Balloon tipped PA catheter
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Emory University
Anesthesia, Postoperative Pain
RIB for Perioperative Analgesia in CIED Patients
Rhomboid intercostal plane block (RIB) has been described in the last decade. Various clinical applications have been found to provide hemithorax analgesia.
- Conditions
- Anesthesia, Postoperative Pain, Arrhythmias, Cardiac
- Trial name
- NCT06449599
- Testing
- ultrasound, parenteral local anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Istanbul University - Cerrahpasa
Ventricular Tachycardia
Anti-arrhythmic Medication v. MRI-Merge Ablation in the Treatment of Ventricular Tachycardia
Ventricular tachycardia (VT) is a morbid arrhythmia responsible for many sudden deaths and ICD shocks. Despite much progress in the treatment of arrhythmia, VT remains a therapeutic challenge.
- Trial name
- NCT00721032
- Testing
- MRI guided VT ablation, Increased dose of amiodarone
- Where
- United States
- Sponsor
- Johns Hopkins University
Cardiac Electrophysiology, Electrocardiogram
Evaluation of Non-invasive Measurement of Electrophysiological "HV" Interval Using a High-density and High-fidelity Signal Averaging ECG Device
His-Ventricle (HV) measurement is only obtained invasively using transvenous catheters. This kind of procedure is routinely performed but some risks of complication exist.
- Trial name
- BIOSEMI-HV (NCT04138797)
- Testing
- Electrophysiological exploration, ECG Biosemi
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Flutter, Atrial, Over 18 Years Old
Hypnosis in Interventional Electrophysiology
Hypnosis has already shown to decrease pain and anxiety in different surgical specialities. Nevertheless, its input has never been studied in cardiology.
- Trial name
- PAINLESS (NCT03250871)
- Testing
- Hypnosis
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Poitiers University Hospital
Atrial Fibrillation
All Inclusive Kodex - EPD Study
This is a post-market, prospective, observational study to evaluate the accuracy of KODEX 3D-imaging. The research study will collect pre-operative and post-operative cardiac imaging data from adult arrhythmia patients who are…
- Trial name
- NCT05489445
- Testing
- KODEX - EPD
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Arizona
Paroxysmal Atrial Fibrillation, Atrial Fibrillation
DiamondTemp™ Ablation System for the Treatment of Paroxysmal Atrial Fibrillation
The purpose of the DIAMOND-AF study is to establish the safety and effectiveness of the DiamondTemp System for the treatment of drug refractory, recurrent, symptomatic paroxysmal atrial fibrillation in patients.
- Trial name
- DIAMOND-AF (NCT03334630)
- Testing
- DiamondTemp Ablation catheter, TactiCath Quartz Ablation catheter
- Where
- 23 sites in United States, Canada and 3 more
- Volunteers
- 482 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Atrial Fibrillation, Atrial Fibrillation, Persistent
Ablation of Focal Activation in Atrial Fibrillation
Recurrent focal electrical activation (or ectopy) superseding sinus activation is the only mechanism proven to drive paroxysmal atrial fibrillation (AF).
- Conditions
- Atrial Fibrillation, Atrial Fibrillation, Persistent, Arrhythmia, Arrhythmias, Cardiac
- Trial name
- RETRO-AF (NCT06402617)
- Testing
- Pulmonary vein isolation, RETRO-Mapping without adjunctive ablation, Adjunctive ablation guided by RETRO-Mapping
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- Imperial College London
Heart Failure
CRT In Narrow QRS Heart Failure: Mechanistic Insights From Cardiac MRI And Electroanatomical Mapping
Cardiac Resynchronisation Therapy (CRT) is a specialist pacemaker procedure that aims to improve the efficiency of the heartbeat.
- Trial name
- NCT03258060
- Testing
- Temporary pacing study, Body Surface Mapping
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Pain, Acute
Impact of Virtual Reality in Cardiac Electrophysiology
Pain during pacemaker or defibrillator implantation can increase patient discomfort, anxiety, and the need for deeper sedation. Using virtual reality (VR) as a non-pharmacological distraction tool may help reduce perceived pain…
- Trial name
- NCT07009951
- Testing
- Virtual reality
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Calabria
Atrial Fibrillation, Ventricular Tachycardia
Introductory Clinical Trial for Measuring Patients Before, During, and After an Electrophysiology (EP) Procedure With a Novel, Body-Worn Sensor
Subjects will be consented to wear the CoVa-2 monitoring system prior to (baseline), during, and after an Electrophysiology Procedure (EP).
- Trial name
- NCT03657134
- Testing
- CoVa-2 Monitoring System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health