Clinical trials: Cardiac Flow
Coronary Artery Disease
Virtual Coronary Intervention and Non-invasive Fractional Flow Reserve (FFR)
The investigators examined the feasibility of treatment planning using virtual coronary revascularization and fractional flow reserve (FFR) CT before the invasive procedures.
- Trial name
- NCT01478100
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Chest Wall Blocks
Serratus Anterior Plan Block (SAP) and Pectoralis (PECSI-II) Blocks on Left Internal Mammarian Artery (LIMA) Blood Flow
To investigate whether the anterior chest wall blocks performed before the surgery have an effect on the LIMA (left internal mammarian artery) blood flow in patients who will undergo coronary artery bypass surgery.
- Trial name
- NCT05907798
- Testing
- LIMA Blood flow
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Congestive Heart Failure (CHF)
Evaluation of Blood Flow Patterns in Lung Blood Vessels Using Ultrasound Technique in Patients With Congestive Heart Failure
Historically, transthoracic Doppler echocardiography has been unable to provide interpretable data of blood flow within the lung parenchyma because of air attenuation of Doppler signals.
- Trial name
- NCT01744210
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Echosense Ltd.
Atherosclerosis and Blood Flow in Coronary Artery
Geometrical Influences on Atherosclerosis and Blood Flow
The study investigates the use of advanced imaging techniques and computational methods to identify high-risk plaques in coronary arteries.
- Trial name
- NCT07002697
- Where
- Bangladesh
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bangladesh University of Engineering and Technology
STEMI - ST Elevation Myocardial Infarction
Noninvasive Artificial Venous Stasis for Reperfusion in STEMI
This prospective, randomized study was designed to evaluate whether the noninvasive artificial venous stasis / RE-START procedure, administered prior to primary percutaneous coronary intervention, increases the frequency of…
- Trial name
- RE-START (NCT07689591)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Firat University
Atherosclerosis, Cardiovascular Disease
A Prospective Study on Predictive Value of Non-Invasive Atherosclerotic Measurements in Elderly Chinese
The purpose of this study is to determine whether non-invasive atherosclerotic measurements (baPWV, IMT, FMD, CACS, ABI) are valuable predictors for cardiovascular events in elderly.
- Trial name
- NCT01208116
- Testing
- Cardiovascular events
- Where
- China
- Volunteers
- 1,290 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University General Hospital
Cardiovascular Diseases, Vasodilation
The Nitrite and Coronary Flow Study
This study is a pharmacodynamic proof of concept study investigating the physiological effects of systemic infusion of nitrite on coronary blood flow using MRI.
- Conditions
- Cardiovascular Diseases, Vasodilation, Hypoxia
- Trial name
- NCT04354051
- Testing
- Sodium Nitrite
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Multi Vessel Coronary Artery Disease
Angiogram Based Fractional Flow Reserve in Patients With Multi-Vessel Disease
This is a prospective, observational, single-center, single-arm, clinical trial designed to assess the efficacy of FFRangio in measuring FFR obtained from angiography compared to Invasive FFR for diagnosing hemodynamically…
- Trial name
- NCT03455244
- Testing
- FFRangio
- Where
- Japan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CathWorks Ltd.
Atrial Fibrillation, Endothelial Function
A Case Control Study to Investigate the Possible Association Between Atrial Fibrillation and Endothelium Dysfunction by Using Flow-Mediated Vasodilation Method
Endothelial function is closely related to the hemostasis , vascular tone, and organ perfusion in cardiovascular system, and its dysfunction would cause overactivation of the coagulative system to induce thrombus formation.
- Trial name
- NCT00173966
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Vascular Disease, Heart Disease
Effects of Urocortins on Forearm Arterial Blood Flow in Healthy Volunteers
Impairment of the heart's pumping capacity (heart failure) remains a major clinical problem with a poor prognosis and the search for novel treatments remains an important area of research.
- Trial name
- NCT01049542
- Testing
- Astressin 2B
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Acute Circulatory Failure
Evaluation of Doppler Flow From the Femoral Artery as a Reflection of Cardiac Flow in a Vascular Fluid Test
In order to identify the responding patients with vascular filling test, this research aims to compare the performance of the increased flow in the femoral artery to the performance of the blood pressure increase.
- Trial name
- RER D (NCT02878369)
- Testing
- Doppler measurement of blood flow in the outflow tract of the left ventricle and the femoral artery,Reading blood pressures displayed on the monitor.
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Pregnancy, Smart Phone Addiction
Effects of Smartphone Addiction to Fetal Parameters in Pregnancy
This prospective cohort study investigates the relationship between smartphone addiction and fetal health parameters at the third trimester of pregnancy.
- Trial name
- ESAFPP (NCT07271680)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Coronary Artery Disease, Coronary Stenosis
Transit Time Flow Measurement in Coronary Surgery
Transit-time flowmetry (TTFM) allows grafts quality control during coronary artery bypass surgery by measuring the flow volume through them.
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Coronary Bypass Graft Stenosis
- Trial name
- COLLATERAL (NCT06471062)
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Coronary Artery Disease, Echocardiography, Stress
New Three-dimensional Methods of Analysis for the Detection of Coronary Artery Disease by Dobutamine Stress Echocardiography
The investigators are going to recruit patients who have a scheduled elective coronary angiography and going to do a dobutamin stress echography (DSE) before the coronary examination.
- Trial name
- 3-DSE (NCT02240745)
- Testing
- Stress-echocardiography
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Aortic Valve Stenosis
CPX in Paradoxical Low Flow Aortic Stenosis
Severe aortic stenosis is a condition with poor life expectancy once it becomes symptomatic. There are no prospective studies illustrating the utility of cardiopulmonary stress (CPX) testing in diagnosing and prognosticating…
- Trial name
- NCT05481814
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Myocardial Infarction
Platelet Leukocyte Aggregates in Acute Cardiac Syndrome vs Healthy Volunteers
This project aims to refine previous studies including the investigators work recently published in August 2012 Journal Thrombosis and Thrombolysis.
- Trial name
- NCT01797016
- Where
- Israel
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Pregnancy Related, Glucose, Low Blood
Interval Versus Continuous Exercise During Pregnancy
The objective of this randomized cross-over design was to investigate the fetal well-being and maternal glycemic response to an acute bout of aerobic high-intensity interval training (HIIT) and moderate-intensity continuous…
- Conditions
- Pregnancy Related, Glucose, Low Blood, Fetal Heart Rate or Rhythm Abnormality Affecting Fetus, Fetal Blood Flow
- Trial name
- NCT05369247
- Testing
- High intensity Interval Training, Moderate Intensity Continuous Training
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Indication, Unlabeled
Clinical Evaluation of 4D Flow Cardiac MRI Sequences
Assess the accuracy of 4D flow cardiac MRI to measure blood flow and velocity, delineate 3D cardiac anatomy and visualize flow dynamics using two (2) different pulse sequences.
- Trial name
- Eval-4DFlow (NCT03986645)
- Testing
- MR data acquisition
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Emanuela Valsangiacomo
Cardiovascular Diseases
Cardiac Rehab and Cerebral Blood Flow Study
This study is being done to better understand the influence of cardiovascular disease on brain blood flow regulation and cognitive function, determine whether exercise-based cardiac rehabilitation can lead to better regulation of…
- Trial name
- NCT05012878
- Testing
- Cardiac rehabilitation - high intensity interval training (HIIT), Cardiac rehabilitation - moderate intensity continuous training (MICT), Cardiac rehabilitation - control
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obstructive Sleep Apnea, Hypertension
Effect of Selective and Nonselective Cyclooxygenase Enzyme Inhibition on Arterial Blood Pressure and Cerebral Blood Flow With Exposure to Intermittent Hypoxia in Humans
The study has been designed to assess the effect of cyclooxygenase inhibition on blood pressure, cerebral blood flow, ventilation and renal hemodynamics following chronic intermittent hypoxia exposure.
- Conditions
- Obstructive Sleep Apnea, Hypertension, Cardiovascular Diseases, Stroke
- Trial name
- NCT01280006
- Testing
- Intermittent hypoxia, Indomethacin, Celecoxib
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Calgary