Clinical trials: Cardiac Health
Heart Failure
The Effect of the MedSentry System on Medication Adherence
The goal of this pilot study to evaluate the effect of the MedSentry system, a multi-faceted medication adherence device and reminder system, on medication adherence and clinical outcomes in heart-failure (HF) patients.
- Trial name
- NCT01814696
- Testing
- MedSentry System
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Massachusetts General Hospital
Heart Failure, Obesity
Fatty Acid Radiotracer Comparison Study in Heart Failure Patients
A single center, open-label baseline controlled imaging study to designed to assess whether Positron Emission Tomography (PET) measurements of myocardial Fatty Acid (FA) metabolism performed with [18F]FluorbetaOx correlates with…
- Conditions
- Heart Failure, Obesity, Type 2 Diabetes Mellitus, Health Normal Volunteer Subjects
- Trial name
- NCT01648296
- Testing
- [18F]FluorbetaOx
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Chronic Heart Failure, Cardiovascular Diseases
AI-Based Monitoring System for Chronic Heart Failure With Advanced Wearable and Mini-Invasive Devices
The goal of this observational, multicenter study is to evaluate whether AI-driven remote monitoring using a mini-invasive wearable device can improve clinical outcomes in adult patients (≥18 years) with chronic heart failure…
- Conditions
- Chronic Heart Failure, Cardiovascular Diseases, Heart Failure With Reduced Ejection Fraction (HFrEF), Heart Failure With Preserved Ejection Fraction (HFPEF)
- Trial name
- SMART-CARE (NCT06909682)
- Testing
- Intervention Group (Device Group - AI-Based Remote Monitoring), Standard Clinical Follow-Up
- Where
- Italy
- Volunteers
- 205 people
- Sponsor
- University of Salerno
COVID-19 Pandemic, Pulmonary Disease, Chronic Obstructive
COVID-19, Patients' Evolution and the Influence of the Pandemic on Health Care and Outcomes in Chronic Diseases
Objectives: 1.- To evaluate the changes in health care and use of services in patients with chronic diseases such as chronic obstructive pulmonary disease (COPD), heart failure and major depression between 2017-2019 and the years…
- Conditions
- COVID-19 Pandemic, Pulmonary Disease, Chronic Obstructive, Heart Failure, Congestive, Depressive Symptoms
- Trial name
- NCT05168722
- Testing
- No interventions
- Where
- 5 sites in Spain
- Volunteers
- 2,220 people
- Sponsor
- Hospital Galdakao-Usansolo
COVID-19, Long COVID
Using Data From a Multisensor Rapid Health Assessment Device to Predict Decompensation in Long COVID (AIDI)
We are conducting a research study at the VA hospital in Bedford, MA to learn more about how a multisensor rapid health assessment device, MouthLab, can help predict or anticipate future health complications in patients with…
- Trial name
- AIDI (NCT05713266)
- Testing
- MouthLabTM
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Edith Nourse Rogers Memorial Veterans Hospital
Cardiac Failure, Renal Failure
Protocolized Diuretic Strategy in Cardiorenal Failure
This research study is a randomized clinical trial to evaluate if taking diuretics (medications that increase urine production and help with fluid removal from the body) in a standardized fashion (using a guideline for adjusting…
- Conditions
- Cardiac Failure, Renal Failure, Kidney Failure
- Trial name
- ProDiuS (NCT01921829)
- Testing
- Protocolized Diuretic Strategy
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Kelly V. Liang, MD
Atrial Fibrillation
The Effect of Arrhythmia Surgery on Quality of Life in Patients With Atrial Fibrillation Undergoing Cardiac Surgery
Atrial fibrillation (AF) is connected with an increased morbidity and mortality. In addition, quality of life is diminished due to palpitations, dyspnea, dizziness and syncope.
- Trial name
- NCT00886080
- Testing
- Pulmonary vein isolation using microwave energy
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Maastricht University Medical Center
Myocardial Infarction, Adherence, Medication
Adherence to Prescribed Medication: Elucidating the Gap Between Guideline Recommendation and Real Life in Myocardial Infarction
The aim of the study is to investigate the adherence to prescribed post-infarction medication and to cardiac rehabilitation in patients after acute myocardial infarction.
- Trial name
- COMPLY (NCT03661710)
- Testing
- Investigating Adherence to Standard of Care Medication and Cardiac Rehabilitation
- Where
- Austria
- Volunteers
- 300 people
- Sponsor
- Medical University of Vienna
Blood Pressure, Heart Rate
Validation of a Smartwatch for Blood Pressure Monitoring
Accurate measurement of blood pressure is essential for the assessment of cardiovascular health and the prevention of cardiovascular disease.
- Conditions
- Blood Pressure, Heart Rate, Oxygen Saturation
- Trial name
- SmartBP (NCT06627920)
- Testing
- Use of the KC08 smartwatch, Beurer PO30 and Omron M7 BP monitor.
- Where
- Spain
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- European University Miguel de Cervantes
Myocardial Infarction (MI), Dyslipidemias
Germany on Target Registry
Germany on Target Registry (DaZiR) is a prospective, Germany-wide patient registry designed to assess lipid management and low-density lipoprotein cholesterol ( LDL-C) target attainment in adults following acute myocardial…
- Trial name
- DaZiR (NCT07835282)
- Testing
- No study-assigned intervention
- Volunteers
- 10,000 people
- Sponsor
- Deutsche Gesellschaft für Lipidologie e. V. (DGFL) - Lipid-Liga
Medication Adherence
Improving Adherence to Pharmacological Treatment
The overall goal of this study was to implement and evaluate the effects of a systems-based and pharmacist-mediated program designed to improve adherence for patients with known coronary heart disease (CHD) to lipid-lowering…
- Trial name
- PACT (NCT00848224)
- Testing
- systems-based and pharmacist-mediated program
- Where
- United States
- Volunteers
- 689 people
- Sponsor
- University of Massachusetts, Worcester
Cardiac Ageing
TO-ChERIsH: Trajectory of Cardiovascular Ageing, Its Determinants and Impact on Health
Specific Aim 1: To determine longitudinal changes in CV ageing (changes in CV imaging) over time. Hypothesis: There are differences in rates of CV ageing over time.
- Trial name
- NCT04501562
- Testing
- Examinations, Cardiovascular Tests, Bio-specimen collection
- Where
- Singapore
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Heart Failure
A Tele-Health Symptom Management Program for Patients With Heart Failure: Pall-Heart
Heart failure is common in adults and is the most common hospital diagnosis in older adults. Patients with heart failure suffer numerous distressing symptoms daily.
- Trial name
- Pall-Heart (NCT04120857)
- Testing
- Gentle Stretching
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Virginia
Psychological Distress, Well-Being, Psychological
Heart Rate Variability Biofeedback in Security Forces
This exploratory study evaluates the effectiveness of a 12-session Heart Rate Variability Biofeedback (HRV-BFB) protocol in reducing distress and burnout while promoting psychological well-being among Portuguese National…
- Conditions
- Psychological Distress, Well-Being, Psychological, Burnout
- Trial name
- GNR-HRVB (NCT07386951)
- Testing
- Heart Rate Variability Biofeedback (HRV-BFB) Training
- Where
- Portugal
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Heart Failure
Pender HPM-Based Online Education and Telephone Follow-Up in Adults With Heart Failure
This randomized controlled trial evaluated the effects of Pender's Health Promotion Model (HPM)-based structured online education combined with planned telephone follow-up on heart failure symptom burden, heart failure-related…
- Trial name
- NCT07017751
- Testing
- HPM-Based Online Education and Telephone Follow-Up
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Naile ALANKAYA
Well-being, Depression
Differential Effect of Four Mindfulness Exercises
Mindfulness can be considered as a family of complex attentional and emotional regulation strategies that promote the cultivation of well-being and emotional balance.
- Conditions
- Well-being, Depression, Anxiety
- Trial name
- NCT02191553
- Testing
- Control group relaxation techniques, Loving-kindness meditation, Body scan
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital Miguel Servet
Cardiovascular Diseases, Heart Diseases
Effects of Resistance and Aerobic Exercise on Cardiovascular Health
This study will investigate the separate and combined effects of aerobic and resistance training on cardiovascular risk factors in overweight men and women with mild to moderate dyslipidemia.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity, Hyperlipidemia
- Trial name
- STRRIDE2 (NCT00275145)
- Testing
- Resistance Training, Aerobic Exercise, Combo
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- Duke University
Eating Behavior Changes
Live Long, Heart Strong: A Digital Nutrition Intervention for Emerging Adults
Live Long, Heart Strong (LLHS) is a theory-guided, digital twin-supported nutrition intervention designed to promote cardiovascular health behaviors among emerging adults (18-25 years).
- Trial name
- LLHS (NCT07732569)
- Testing
- Live Long, Heart Strong (LLHS) Digital Nutrition Intervention, Static Digital Nutrition Education Toolkit
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Aortic Valve Stenosis, Iron Deficiency
Iron Infusion in Patients Undergoing Transcatheter Aortic Valve Implantation
The aim of the open-label, randomized controlled superiority IRON TAVI trial is to investigate whether intravenous iron therapy (ferric carboxymaltose) improves Health-Related Quality of Life (HRQOL) in patients with severe…
- Conditions
- Aortic Valve Stenosis, Iron Deficiency, TAVI(Transcatheter Aortic Valve Implantation), Cardiovascular Diseases
- Trial name
- IRON TAVI (NCT07370688)
- Testing
- Intravenous ferric carboxymaltose
- Where
- Netherlands
- Volunteers
- 402 people
- Sponsor
- Erasmus Medical Center
Heart Attack Patients
Application of the Health Action Process Approach Model Program to Patients With Heart Attacks
This research is conducted to determine whether the nurse-led Health Action Process Approach Model-based Cardiac Rehabilitation Program is effective in patients with myocardial infarction.
- Trial name
- NCT06951958
- Testing
- Cardiac Rehabilitation Program Based on Health Action Process Approach Model
- Volunteers
- 70 people
- Sponsor
- TC Erciyes University
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