Clinical trials: Cardiac Infection
Acute Myocardial Infarction, Cardiovascular Diseases
Effect of infLuenza vaccInation After Myocardial INfArction on Cardiac inflammaTory responsE
The goal of this randomized, double-blind, placebo-controlled clinical trial is to investigate the immunological effects of influenza vaccination outside of the influenza season on arterial inflammation in patients with a recent…
- Conditions
- Acute Myocardial Infarction, Cardiovascular Diseases, Inflammatory Response
- Trial name
- ELIMINATE (NCT06336317)
- Testing
- Influenza vaccine
- Where
- 3 sites in Denmark, Sweden and 1 more
- Volunteers
- 90 people
- Sponsor
- Region Örebro County
Infections, Heart Failure
Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes
Sub-optimal transfer of clinical information during inter-hospital transfer (IHT, the transfer of patients between acute care hospitals) is common and can lead to patient harm.
- Conditions
- Infections, Heart Failure, COPD Exacerbation, Asthma
- Trial name
- NCT05443321
- Testing
- Health Information Exchange (HIE) platform
- Where
- United States
- Volunteers
- 1,006 people
- Sponsor
- Brigham and Women's Hospital
SIRS, Cytokine Storm
Cytokine Hemoadsorption in ECMO Patients
Cytokine hemoadsorption is a novel therapy used to improve outcome in critically ill patients with a dysregulated cytokine response and hemodynamic instability.
- Conditions
- SIRS, Cytokine Storm, Cardiogenic Shock, Cardiac Arrest
- Trial name
- NCT04901338
- Where
- Slovenia
- Volunteers
- 25 people
- Sponsor
- University Medical Centre Ljubljana
Infective Endocarditis
PRetest prObability of Infectious ENDOCARDITIS for Appropriate Criteria Regarding Transesophageal ECHOcardiography in Tertiary Care Facilities (PRO ENDOCARDITIS ECHO-Study)
Infective endocarditis is a potentially lethal disease that has undergone major changes over the last decades. The Duke Criteria are recommended for evaluation of probability of presence of infective endocarditis by current ESC…
- Trial name
- NCT03365193
- Testing
- Transesophageal Echocardiography
- Where
- Germany
- Volunteers
- 263 people
- Sponsor
- University Hospital, Essen
Covid19
Patterns of Arrhythmias and Conduction Block in COVID-19 Patients and Its Relation to Myocardial Injury Detected by Cardiac Magnetic Resonance
Detection of the incidence and types of arrhythmia and conduction block in COVID - 19 patients Detection and description of CMR patterns of myocardial injury in COVID-19 patients with arrhythmias.
- Trial name
- NCT04584411
- Testing
- Cardiac Magnetic resonance imaging
- Volunteers
- 50 people
- Sponsor
- Assiut University
Congestive Heart Failure, Angina Pectoris
Does Telephone Follow-up Improve Patients Satisfaction
Several studies have shown the importance of Telephone follow-up in reducing hospital readmissions for heart failure. Therefore, we aimed in this cohort to investigate whether telephone follow-up with patients discharged from the…
- Conditions
- Congestive Heart Failure, Angina Pectoris, Pneumonia, Urinary Tract Infection
- Trial name
- NCT00192738
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Rambam Health Care Campus
Chagas Cardiomyopathy
A Trial Testing Amiodarone in Chagas Cardiomiopathy
Purpose: The ATTACH trial, as currently designed, will primarily test whether a treatment with Amiodarone for at least 6 months has a trypanocidal effect among individuals with mild-to-moderate Chronic Chagas Cardiomyopathy.
- Trial name
- ATTACH (NCT03193749)
- Testing
- Amiodarone Hydrochloride
- Where
- Colombia
- Volunteers
- 200 people
- Sponsor
- Fundación Cardioinfantil Instituto de Cardiología
Heart Transplant Infection, CMV Infection
Multicenter Clinical Trial to Evaluate the Efficacy of a Preventive Strategy Against CMV Infection in Heart Transplant Patients, Based on the Specific T Cells Response
This study evaluates the efficacy and safety of an individualized preventive strategy against CMV infection in CMV seropositive heart transplant patients based on the specific basal response of the lymphocytes againts CMV…
- Trial name
- ELISPOT-TC (NCT04278547)
- Testing
- ELISPOT IFN-γ assay
- Where
- Spain
- Volunteers
- 188 people
- Sponsor
- Hospital Universitari de Bellvitge
Coronary Artery Disease, Human Immunodeficiency Virus (HIV)
Pericardial Fat and Inflammation in HIV Patients and Controls
The investigators propose to correlate 1) cardiac MRI pericardial adipose volume, 2) the presence of pericardial monocytes and 3) circulating immune biomarkers in persons with and without CHD and HIV infection compared to…
- Trial name
- NCT02399384
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Cincinnati
Acquired Immunodeficiency Syndrome, Arrhythmia
Cardiac Autonomic Control in Children of HIV Positive Mothers
To establish the incidence, clinical spectrum, and natural history of cardiac dysautonomia as defined by heart rate spectral analysis in both HIV infected and noninfected children and to evaluate the value of heart rate spectral…
- Conditions
- Acquired Immunodeficiency Syndrome, Arrhythmia, Heart Diseases, HIV Infections
- Trial name
- NCT00005353
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Infective Endocarditis
Infective Endocarditis in Developing Countries, a Prospective, Observational, Multicentre Study
Introduction. Comprehensive data on infective endocarditis in developing countries are scarce. Objectives: Description of the characteristics (clinical and microbiological) and assessment of the outcomes of infective endocarditis…
- Trial name
- EndoDev (NCT02128139)
- Where
- 6 sites in Fiji, Laos and 3 more
- Volunteers
- 300 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Escalation of Care, Cardiopulmonary Arrest
Early Warning System for Clinical Deterioration on General Hospital Wards
The goal is to develop a two-tiered monitoring system to improve the care of patients at risk for clinical deterioration on general hospital wards (GHWs) at Barnes-Jewish Hospital (BJH).
- Conditions
- Escalation of Care, Cardiopulmonary Arrest, Respiratory Arrest, Severe Sepsis
- Trial name
- NCT01280942
- Testing
- EWS Nursing Alerts, Wireless Remote Sensor
- Where
- United States
- Volunteers
- 20,031 people
- Sponsor
- Washington University School of Medicine
Infective Endocarditis
Predisposition to Infectious Endocarditis
To evaluate the gender-related elements, a first step will be to analyze the impact of sex ratio on different parameters such as age in endocarditis and the type of underlying valvulopathy and other associated comorbidities.
- Trial name
- NCT03979261
- Testing
- evolution of sex ratio according to age
- Where
- France
- Volunteers
- 450 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Multiple Organ Dysfunction, Sepsis
Validation of Hematological Indices
The hypothesis of the study is that hematological indices (neutrophil to lymphocyte ratio, platelet to lymphocyte ratio and systemic index of inflammation) may be predictors of infectious complications and multiple organ…
- Conditions
- Multiple Organ Dysfunction, Sepsis, Pneumonia, Wound Infection
- Trial name
- NCT06476171
- Testing
- Determination of the level of the studied biomarkers
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Petrovsky National Research Centre of Surgery
HIV Infections, Atherosclerosis
Antiretrovirals and Rate of Progression in Carotid Artery Intima-medial Thickness in HIV
It is well known that HIV-infected subjects frequently experience hyperlipidemias, insulin resistance, and visceral adiposity, which are known to increase the risk of atherosclerosis.
- Trial name
- NCT00575939
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Chronic Heart Failure, Chronic Kidney Diseases
ODYSSEE-vCHAT Mental Health Program for Heart Failure and Kidney Disease Patients
INTRODUCTION Psychological distress and reduced quality of life are prevalent in patients with chronic heart failure (CHF) and advanced chronic kidney disease (CKD).
- Trial name
- ODYSSEEvCHAT (NCT05560737)
- Testing
- ODYSSEE-vCHAT
- Where
- 4 sites in Canada
- Volunteers
- 215 people
- Sponsor
- University Health Network, Toronto
Coronary Heart Disease, Heart Failure
Cardiovascular Diseases in HIV-infected Patients HIV-HEART Study: 5 Years Follow-up
HIV-infection is associated not only with a reduced function of the immune system, but also linked with diseases of other organ systems, in particular with the heart.
- Conditions
- Coronary Heart Disease, Heart Failure, HIV, AIDS
- Trial name
- NCT01196273
- Testing
- Comprehensive non invasive cardiovascular examination
- Where
- 5 sites in Germany
- Volunteers
- 1,424 people
- Sponsor
- University Hospital, Essen
Sepsis, Cardiac Arrest
Thigh Muscle Mass and Muscle Wasting in Patients in the Emergency Department
The goal of this observational study is to evaluate whether thigh muscle mass and muscle wasting are associated with mortality in patients who visit the emergency department.
- Conditions
- Sepsis, Cardiac Arrest, Acute Respiratory Failure, Patients Who Visit Emergency Department
- Trial name
- NCT05978154
- Testing
- Thigh muscle mass and muscle wasting (exposure)
- Where
- South Korea
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Korea University Ansan Hospital
Influenza, Human
A Study to Evaluate the Effect of Intravenous Zanamivir on Cardiac Conduction in Healthy Volunteers
Approximately 40 healthy subjects will be enrolled. Each subject will participate in the study for approximately 9 weeks. There will be four treatment sequences with a 5-7 day washout between treatments.
- Trial name
- NCT01353729
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
COVID-19, Heart Rate
Effect of Mask Use on Hemodynamic Responses During Exertion
The use of masks is a necessity due to the current pandemic conditions. The aim of the study is to examine the effects of the use of masks during effort on dyspnea and fatigue with hemodynamic parameters.
- Conditions
- COVID-19, Heart Rate, Blood Pressure, Exercise Test
- Trial name
- NCT05401331
- Testing
- Treadmilll, mask
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
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