Clinical trials: Cardiac Inflammation
Inflammation
Anti-inflammatory Actions of Osteopathic Manipulative Treatment
This study evaluates the hypothesis that osteopathic manipulative treatment (OMT) and non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) elicit anti-inflammatory actions through activation of the…
- Trial name
- OMT_taVNS (NCT04177264)
- Testing
- Occipito-Atlantal Decompression (OA DC), Splenic Lymphatic Pump Technique (SpLPT), Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Burrell College of Health Sciences
Heart Failure, Sepsis
Skeletal Muscle Oxygenation in Critically Ill
It is possible to measure skeletal muscle tissue oxygenation (StO2) using near infrared spectroscopy(NIRS). It is performed non invasively.
- Conditions
- Heart Failure, Sepsis, Septic Shock, Cardiogenic Shock
- Trial name
- NCT00384644
- Testing
- NiRS measurment of tissue oxygenation
- Where
- Slovenia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Heart Failure, Sudden Cardiac Death
Marathon, Genetics, Inflammation and the Cardiovascular System: MAGIC-Trial
The purpose of the study is to determine the myocardial function and vascular adaptation after strenuous exercise in association with genotype/polymorphisms.
- Trial name
- MAGIC (NCT00845286)
- Testing
- Munich Marathon
- Where
- Germany
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Coronary Heart Disease
Efficacy of Sterol Enhanced Soy Beverage on Cholesterol Metabolism, Inflammation and Oxidative Status in Humans
It is becoming increasingly clear that North Americans prefer dietary approaches to enhance health in favour of pharmaceutical approaches.
- Trial name
- NCT00924391
- Testing
- phytosterol enhanced soy based beverage, 1% milk
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Cardiac Output, Endotoxemia
Echocardiographic Changes After 3-hydroxy Butyrate+Whey Intake
This study evaluates the cardiovascular effects of adding the ketone body 3-hydroxy butyrate (3-OHB) to whey protein during human endotoxemia.
- Conditions
- Cardiac Output, Endotoxemia, Catabolic State, Echocardiography
- Trial name
- NCT04037722
- Testing
- Whey, 3-OHB + Whey
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cardiovascular Injury
Cardiovascular Effects of Exposure to Ozone
The Multicenter Ozone Study in Elderly Subjects will investigate whether short-term exposure of elderly volunteers to ambient levels of ozone in a controlled exposure setting causes acute cardiovascular responses as assessed by…
- Trial name
- MOSES (NCT01487005)
- Where
- 4 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Health Effects Institute
Adrenal Gland Hyperfunction, Cardiovascular Disease
Heart Disease Risk Factors in Major Depression
A series of studies in patients with major depression have consistently demonstrated a doubling of the mortality rate at any age, independent of suicide.
- Conditions
- Adrenal Gland Hyperfunction, Cardiovascular Disease, Involutional Depression
- Trial name
- NCT00001969
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Neonatal Sepsis, Markers
Tissue Doppler Echocardiographic Assessment of Cardiac Function in Neonatal Sepsis
1. To assess myocardial function in neonates with sepsis using tissue doppler echocardiography. 2. To assess sepsis induced cardiac dysfunction. 3.
- Trial name
- NCT07572916
- Testing
- cardiac troponin, and blood culture
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Reperfusion Injury
Diagnostics for the Reperfusion Injury Following MI
The primary purpose of this study is to correlate new cardiac imaging modalities (2D, 3D echocardiography, contrast echocardiography, strain analysis and cardiac MRI) to biochemical parameters as the L-arginine-nitric oxide…
- Trial name
- NCT00529607
- Testing
- contrast echocardiography, 2D and 3D echocardiography, cardiac MRI
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Heart Failure With Preserved Ejection Fraction (HFPEF)
The Effect of Adiposity on Muscle and Microvascular Function in HFpEF
This project is an observational study in patients with heart failure with preserved ejection fraction (HFpEF) who are candidates for treatment with weight loss medication to manage obesity or diabetes as part of their standard…
- Trial name
- NCT06930495
- Testing
- Weight loss SOC Treatment with second generation anti-diabetic medications
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Heart Diseases, Microbial Colonization
Dairy Fat and Fermentation Study
The purpose of the study is to compare the effect of consuming full-fat (regular) and fat-free (skim) milk, as well as full-fat and fat-free yogurt (a fermented dairy product), on microorganisms in your gut as well as the…
- Conditions
- Heart Diseases, Microbial Colonization, Inflammation
- Trial name
- NCT05840081
- Testing
- Milk or yogurt beverage
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Tufts University
Myocardial Inflammation
COUREUR Study Myocardial Inflammation in Cyclist Part 2
The study will evaluate myocardial inflammation in cyclists after high intense and sustained exercise. Our hypothesis is that strenuous exercise in recreational cyclists may be associated with myocardial inflammation.
- Trial name
- NCT05138003
- Testing
- cardiac MRI, Echocardiography, RootiRx for the ECG monitoring during the cycling ride
- Where
- 2 sites in Belgium, France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Patients With Post Orthotopic Heart Transplantation Status
iNOS With Positron Emission Tomography (PET) in Cellular Inflammation.
The primary purpose of this study is to measure the level of an enzyme in a patient's heart called inducible nitric oxide synthase(iNOS) using Positron Emission Tomography (PET) imaging with a radioactive tracer called 18F-NOS.
- Trial name
- F-NOS (NCT01066637)
- Testing
- [18F](+/-)NOS
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine