Clinical trials: Cardiac Intensive Care Unit
Hypoxemia, Arrhythmias
Differences in Morbidity Between a Necessity Endotracheal Suctioning Protocol Versus a Routine Endotracheal Suctioning
Morbidity frequency associated to a endotracheal suctioning is different between a necessity endotracheal suctioning protocol versus a routine endotracheal protocol.
- Conditions
- Hypoxemia, Arrhythmias, Cardiac Arrest, Ventilator Associated Pneumonia
- Trial name
- NCT01069185
- Testing
- Necessity endotracheal suctioning, Routine endotracheal suctioning
- Where
- Colombia
- Volunteers
- 92 people
- Sponsor
- Hospital Pablo Tobón Uribe
Heart Arrest
Unexpected Cardiac Arrest in Intensive Care Unit
Unexpected cardiac arrest involves approximately 0.5 to 5% of patients admitted in Intensive Care Unit (ICU). Even if they have a technical environment conducive to prompt diagnosis and prompt treatment, patients hospitalized in…
- Trial name
- ACIR (NCT03021564)
- Testing
- cardiopulmonary resuscitation
- Where
- 45 sites in France
- Volunteers
- 677 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Noise Exposure, Sedative Withdrawal Delirium
Sound Levels in the Pediatric Cardiac Critical Care Unit and Their Correlation With Sedation Administration, Delirium Scores and Patient Heart Rate
There is limited data regarding sound levels and burden in the pediatric cardiac critical care unit and how this compares with WHO standards.
- Conditions
- Noise Exposure, Sedative Withdrawal Delirium, Sedative Toxicity
- Trial name
- NCT04777695
- Testing
- Decibel Monitor
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Children's National Research Institute
Out-Of-Hospital Cardiac Arrest
REmote COnditioning in Out-of-Hospital Cardiac Arrest
Out-of-Hospital Cardiac Arrest remains a major public health problem, resulting in high mortality largely related to multiple organ failure and poor neurological outcomes due to brain anoxia.
- Trial name
- RECO-OHCA (NCT06306625)
- Testing
- Remote ischemic conditioning, No remote ischemic conditioning
- Where
- 14 sites in France
- Volunteers
- 220 people
- Sponsor
- Hospices Civils de Lyon
Acute Coronary Syndrome, Intensive Care Unit Syndrome
In Hospital Course of Acute Coronary Artery Syndromes
While international guidelines have indicated that use of a routine invasive strategy was favored for high-risk patients with NSTE-ACS and for all STE- ACS, the lower risk patients successfully reperfused and carrefully selected…
- Trial name
- HACSA (NCT04378504)
- Where
- France
- Volunteers
- 269 people
- Sponsor
- University Hospital, Montpellier
Cardiac Arrythmias
Pilot Study for the Tight K Study
The primary purpose of this pilot study will be feasibility of recruitment. However, in order to further inform a full randomised controlled trial (RCT), information on the incidence of atrial fibrillation (AF) and other…
- Trial name
- TightK (NCT03195647)
- Testing
- Potassium
- Where
- 2 sites in United Kingdom
- Volunteers
- 160 people
- Sponsor
- Barts & The London NHS Trust
Febrile Neutropenia, Endocarditis
Diagnosis of Septicaemia by Detection of Microbial DNA in Blood in Severe Infections
The primary purpose is to improve and quicken the microbial diagnosis in severe infections, since only one third of the cases are documented by blood cultures and adequate anti-infective therapy in the 48 hours reduced mortality…
- Conditions
- Febrile Neutropenia, Endocarditis, Severe Sepsis
- Trial name
- EVAMICA (NCT00709358)
- Testing
- Detection of microbial DNA in blood by SeptiFast®, detection of microbial DNA in blood by blood culture
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intensive Care Unit, Coronary Artery Bypass Grafting (CABG)
Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients
The MODIFY CSX study is a prospective, randomized, placebo-controlled trial conducted in heart centers in Germany and Italy. A total of 550 high-risk cardiac surgery patients will receive either 0.20 g fish oil/kg body weight…
- Conditions
- Intensive Care Unit, Coronary Artery Bypass Grafting (CABG), High Risk Patients, Cardiopulmonary Bypass
- Trial name
- MODIFY CSX (NCT06279793)
- Testing
- Fish Oil, Intravenous 0.9% Sodium Chloride
- Where
- 10 sites in Germany
- Volunteers
- 550 people
- Sponsor
- GCP-Service International West GmbH
Shock
Vasoactive Drugs in Intensive Care Unit
The investigators hypothesis is that for ICU patients with shock, the use of the vasoactive drugs phenylephrine and vasopressin will reduce tachydysrhythmias when compared to norepinephrine and epinephrine.
- Trial name
- NCT02118467
- Testing
- Norepinephrine, Epinephrine, Phenylephrine
- Where
- United States
- Volunteers
- 836 people
- Sponsor
- University of Chicago
Pediatric Congenital Heart Surgery
Predictive Value of the FORE-SIGHT™ Monitor for Hemodynamic Deterioration
The postoperative period after congenital heart surgery in children can be a very critical episode, where it is of utmost importance to closely monitor the circulation in these patients.
- Trial name
- NCT01706497
- Testing
- Cerebral tissue oxygen saturation monitoring, blinded
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- KU Leuven
Atrial Fibrillation, Critical Illness
Post Intensive Care Unit Atrial Fibrillation
Atrial fibrillation (AF) is a common heart rhythm disorder in the intensive care unit (ICU). It can be precipitated by multiple factors but it is unclear whether AF persists after discharge from the ICU, and long term.
- Trial name
- PIAF (NCT05860894)
- Testing
- Implantable ECG holter device (Biomonitor3, Biotronik)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Covid19, Myocardial Infarction
Outcomes of Patients Who Survived Treatment on an Intensive Care Unit for COVID-19 in England and Wales
This retrospective cohort study aims to characterise outcomes for patients treated on an intensive care unit (ICU) with COVID-19 in England and Wales, one year after discharge from hospital.
- Conditions
- Covid19, Myocardial Infarction, Stroke, Critical Illness
- Trial name
- OPTIC-19 (NCT04838106)
- Testing
- Not applicable as observational study
- Where
- United Kingdom
- Volunteers
- 319,600 people
- Sponsor
- University of Oxford
Dysfunction, Left Ventricular
Ultrasound and Left Ventricular Systolic Function
The aim of this study is to evaluate, in an intensive care unit, the reproducibility between two non-cardiologists operators and a cardiologist expert in echocardiogram, of the Simpson method and of the calculation of GLS for the…
- Trial name
- EFESE (NCT02381756)
- Testing
- Ultrasound
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Critical Illness, Critically Ill Patients
Physiological Changes in Adult Intensive Care Patients Following Contact With Their Primary Caregiver
Patients admitted to intensive care units are exposed to multiple environmental and clinical factors that may affect their physiological responses.
- Trial name
- CARE-ICU (NCT07761364)
- Testing
- Standardized therapeutic physical contact
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Universidad Autonoma del Estado de Mexico
Respiration, Artificial, Positive-Pressure Respiration
VENtilation Modalities During Transport of PostoperatIve CRITically Ill Patients to the ICU
Patients undergoing major non-cardiac surgery may require postoperative mechanical ventilation and transfer from the operating room to the intensive care unit (ICU).
- Conditions
- Respiration, Artificial, Positive-Pressure Respiration, Postoperative Complications (Cardiopulmonary), Postoperative Complications
- Trial name
- VENTICRIT (NCT07646249)
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva
Intensive Care Unit, Cardiac Surgery
Comparison of Two Methods for Assessing Cough Capacity in Intensive Care Unit After Cardiac Surgery
Weaning from mechanical ventilation represents 50% of the time spent under mechanical ventilation (1). The risk factors identified in the failure to wean from mechanical ventilation are: left heart dysfunction with LVEF < 30%.
- Trial name
- DEPT (NCT03983044)
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Cardiac Output, High, Cardiac Output, Low
Using Minimally Invasive Cardiac Output Data vs. Standard Care for Patients Emergently Admitted to the Intensive Care Unit Who Are Hemodynamically Unstable
The purpose of this study is to evaluate if the continuous availability of minimally invasive cardiac output data during treatment in the intensive care unit (ICU) for hemodynamic instability, in comparison to standard of care…
- Trial name
- NCT00354211
- Testing
- minimally invasive cardiac output system consisting of arterial line sensor and cardiac output bedside monitor (device)
- Where
- 3 sites in Finland, Switzerland
- Volunteers
- 392 people
- Sponsor
- Edwards Lifesciences
Non-ST Elevated Myocardial Infarction
Low Risk Non ST Elevation Myocardial Infarction With or Without Intensive Care Unit Admission
Favourable in-hospital outcome is observed in numerous patients after Non ST myocardial infarction (NSTEMI) with invasive strategy but European guidelines proposed systematic intensive care unit monitoring up to 24 h in lower…
- Trial name
- SELECTNSTEMI (NCT05153889)
- Testing
- Hospitalized in Intensive care unit, Hospitalized in General cardiology ward
- Where
- 3 sites in France
- Volunteers
- 320 people
- Sponsor
- University Hospital, Montpellier
Atrial Fibrillation
Long-term Recurrence Rates of Atrial Fibrillation Following New-onset Atrial Fibrillation During ICU Admission
The Primary Objective of the study is to establish the One-year recurrence rates of atrial fibrillation (AF) following new-onset atrial fibrillation during intensive care unit (ICU) admission.
- Trial name
- NCT05151523
- Volunteers
- 100 people
- Sponsor
- Katia Orvin
Respiratory Failure, Mechanical Ventilation Complication
Effect of Sedation Strategy on Duration Mechanical Ventilation in Patient After Cardiac Surgery
There is a direct relationship between the sedative agent and the duration of ventilation.
- Conditions
- Respiratory Failure, Mechanical Ventilation Complication, Sedation Complication
- Trial name
- NCT05451121
- Testing
- Propofol, Dexmedetomidine, Propofol and dexmedetomidine
- Where
- Ukraine
- Volunteers
- 356 people
- Sponsor
- Anesthesia Research Group UA