Clinical trials: Cardiac Magnetic Resonance
Acute Myocardial Infarction
The Effects of Facilitated Percutaeous Coronary Intervention in Acute Myocardial Infarction
The purpose of this study to investigate whether the administration of high-dose tirofiban before primary PCI could reduce myocardial infarct size, using analysis of contrast-enhanced magnetic resonance imaging.
- Trial name
- NCT00611169
- Testing
- tirofiban
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Pulmonary Artery Hypertension, Congenital Heart Disease
Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive Guidewires
Background: A heart catheterization is a diagnostic heart procedure used to measure pressures and take pictures of the blood flow through the heart chambers.
- Conditions
- Pulmonary Artery Hypertension, Congenital Heart Disease, Structural Heart Disease
- Trial name
- NCT03152773
- Testing
- MRI Heart guidewire catheterization
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Myocardial Infarction, Inflammation
Inflammatory Cell Trafficking After Myocardial Infarction
Myocardial infarction (heart attack) is usually the consequence of rupture of a fatty 'plaque' in a heart artery. The presence of this fat and debris causes the propagation of a blood clot and blockage of the artery.
- Trial name
- NCT01127113
- Testing
- Infusion of investigational product, Cardiac magnetic resonance imaging
- Where
- United Kingdom
- Sponsor
- University of Edinburgh
Cardiovascular Diseases
Canadian Alliance for Healthy Hearts and Minds
The Cardiac, Vascular and Cognitive Dysfunction (CVCD) Alliance will be a prospective, multi-ethnic cohort study in healthy Canadian individuals between 35 and 69, looking at contextual risk factors and novel predictors of hard…
- Trial name
- NCT02220582
- Testing
- MRI
- Where
- 12 sites in Canada
- Volunteers
- 7,900 people, healthy volunteers welcome
- Sponsor
- Montreal Heart Institute
Atrial Fibrillation, Stroke
Advanced Cardiac Imaging To Predict Embolic Stroke On Brain MRI: A Pilot Study
Demonstrating the pathophysiological link between Left Atrial (LA) and Left Atrial Appendage (LAA) pathology and embolic strokes in non-Atrial Fibrillation (AF) individuals represents a major advance in stroke prevention…
- Conditions
- Atrial Fibrillation, Stroke, Stroke, Cardiovascular, Vascular Cognitive Impairment
- Trial name
- NCT04769310
- Testing
- Cardiac and Brain MRI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Tulane University
Hypertrophic Obstructive Cardiomyopathy \(HOCM\), Neurologic Evaluation
Neurologic Evaluation of Patients After Transapical Beating-Heart Septal Myectomy
The goal of this prospective cohort study is to evaluate the neurologic changes in patients that received transapical beating-heart septal myectomy.
- Conditions
- Hypertrophic Obstructive Cardiomyopathy \(HOCM\), Neurologic Evaluation, Magnetic Resonance Imaging \(MRI\), Transapical Beating-Heart Septal Myectomy
- Trial name
- NCT06078410
- Testing
- Cardiac surgery
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xiang Wei
Heart Failure
Age Gender Left Ventricular Mass and Cardiac Troponin T
The purpose of this study is to determine the influence of functional or anatomic cardiac parameters, age and gender on high sensitivity cTnT (TnThs) levels in healthy individuals.
- Trial name
- NCT01100710
- Where
- Germany
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Pulmonary Arterial Hypertension
Study of Cardiac MRI in the Follow up Assessment of Patients With PAH (EVITA)
Pulmonary arterial hypertension (PAH) is characterized by a progressive increase in pulmonary vascular resistance leading to right ventricular failure and eventually to death.
- Trial name
- EVITA (NCT02845518)
- Testing
- Cardiac magnetic resonance imaging (cMRI)
- Where
- France
- Volunteers
- 169 people
- Sponsor
- Central Hospital, Nancy, France
Cardiac Arrest
Prehospital Resuscitation Intranasal Cooling Effects Seen in MRI of the Brain After Cardiac Arrest
Therapeutic hypothermia improves the neurologically-intact survival rates in those patients resuscitated out-of-hospital from ventricular fibrillation. Cooling as early as possible might be beneficial to those victims.
- Trial name
- COOLCAMRI (NCT02179060)
- Where
- Finland
- Volunteers
- 12 people
- Sponsor
- Tampere University Hospital
Cardiac Rhythm Disorder
3T MRI CIED Post-Approval Study
The purpose of this study is to evaluate product performance of Magnetic Resonance (MR) Conditional Cardiac Implantable Electronic Devices (CIED) following 3 tesla (3T) MRI exposure.
- Trial name
- NCT02969395
- Where
- 204 sites in United States, Belgium and 20 more
- Volunteers
- 41 people
- Sponsor
- Medtronic
Heart Defects, Congenital
Impact of Congenital Heart Disease on Neurodevelopmental Outcome
The project aims toward clarifying the underlying mechanism and the long-term impact of congenital heart disease on neurodevelopment.
- Trial name
- NCT03871881
- Testing
- Magnetic Resonance Imaging, Neuropsychological assessment
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Myocarditis
Magnetic Resonance Imaging in Myocarditis
The purpose of this study is the assess the diagnostic performance of magnetic resonance imaging in patients with suspected myocarditis by applying different imaging sequences at different MR scanners
- Trial name
- MyoRacer (NCT02177630)
- Testing
- Endomyocardial Biopsy
- Where
- Germany
- Volunteers
- 129 people
- Sponsor
- Heart Center Leipzig - University Hospital
Coronary Artery Disease, Asthma
Comparison of Dobutamine and Regadenoson Stress Cardiac Magnetic Resonance (MR)
The goal of this research is to determine the utility of Regadenoson (Lexiscan)for use as an imaging agent with cardiac MR. If found useful, it will help us establish a protocol for regadenoson stress MR perfusion (Regadenoson…
- Conditions
- Coronary Artery Disease, Asthma, Chronic Obstructive Pulmonary Disease (COPD), Angina
- Trial name
- NCT00763035
- Testing
- Regadenoson, Dobutamine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Wake Forest University Health Sciences
Sudden Cardiac Death Due to Cardiac Arrhythmia, Dilated Cardiomyopathy
Arrhythmic Risk Stratification in Nonischemic Dilated Cardiomyopathy
Nonischemic dilated cardiomyopathy is a heterogeneous disease often associated with increased rates of sudden cardiac death. Although many algorithms have been proposed, risk stratification remains suboptimal, and implantable…
- Trial name
- ReCONSIDER (NCT04246450)
- Testing
- Implantable Cardioverter Defibrillator (ICD) insertion
- Where
- Greece
- Volunteers
- 675 people
- Sponsor
- University of Athens
Myocardial Infarction
Optical Coherence Tomography in Patients With Acute Myocardial Infarction and Nonobstructive Coronary Artery Disease
The purpose of this study is to evaluate the prevalence and morphological features of coronary plaques by means of OCT in patients with acute myocardial infarction but without any significant coronary stenosis at coronary…
- Trial name
- SOFT-MI (NCT02783963)
- Testing
- OCT and CMR imaging
- Where
- Poland
- Volunteers
- 38 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Ischemic Heart Disease, Coronary Artery Disease
Evaluating Myocardial Ischemia in Chest Pain Using Exercise CMR
Ischemic Heart Disease (IHD) is a condition of recurring chest pain or discomfort that occurs when a part of the heart is not receiving sufficient blood flow.
- Conditions
- Ischemic Heart Disease, Coronary Artery Disease, Cardiovascular Diseases, Myocardial Ischemia
- Trial name
- EMPIRE (NCT03217227)
- Testing
- Cardiovascular Magnetic Resonance Imaging with Exercise Bike, Cardiac Catheterization, Retinal Photography (Optional)
- Where
- 2 sites in Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Endothelial Dysfunction, Myocardial Perfusion Abnormalities
Cardiac Magnetic Resonance Imaging for Detecting Endothelial Dysfunction
The goal of this research study is to demonstrate that Cardiac Perfusion MRI with Vasomotor Stress may serve as a non-invasive and less risky imaging technique for detecting non-obstructive perfusion deficits and/or abnormalities…
- Conditions
- Endothelial Dysfunction, Myocardial Perfusion Abnormalities, Cardiac MRI Perfusion With Vasomotor Stress, Diabetes
- Trial name
- NCT00808535
- Testing
- Cardiac Perfusion MRI w Vasomotor Stress
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Pulmonary Hypertension, Pulmonary Arterial Hypertension
Early Detection of Pulmonary Arterial Hypertension Using Cardiac Magnetic Resonance Imaging
Cardiac magnetic resonance imaging has emerged as a potential valuable test for the early detection of Pulmonary Arterial Hypertension.
- Trial name
- NCT01451255
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cardiovascular Disease, Healthy
Technical Evaluation of Cardiovascular Magnetic Resonance Imaging and Spectroscopy
Magnetic resonance imaging (MRI) and spectroscopy are diagnostic tools that create high quality images of the human body without the use of X-ray (radiation).
- Trial name
- NCT00001874
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Congenital Heart Disease
SVR III: Brain Connectome and Neurodevelopmental Outcomes
Patients with hypoplastic left heart syndrome and other single right ventricle lesions who have undergone the Fontan procedure have a high risk of neurodevelopmental disorders that affect quality of life and adulthood employment.
- Trial name
- SVRIII (NCT02692443)
- Testing
- Magnetic Resonance Imaging, Neurodevelopmental Testing
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh