Clinical trials: Cardiac Magnetic Resonance
Myocardial Diseases, Perfusion Imaging
Validation of Myocardial Perfusion and Extracellular Volume Assessment Using Photon-Counting Computed Tomography (PCCT) Compared With Cardiac Magnetic Resonance (CMR) in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI)
Cardiovascular diseases are the leading cause of death worldwide, responsible for about 30% of all deaths. This substantial burden highlights the need for accurate diagnostic tools that help doctors detect heart disease early and…
- Conditions
- Myocardial Diseases, Perfusion Imaging, Stress Perfusion, Myocardial Fibrosis
- Trial name
- NCT07799363
- Testing
- Stress myocardial perfusion imaging with PCCT. Extracellular volume quantification with PCCT.
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska University Hospital
Left Ventriclar Mass
Metformin Reduces Left Ventricular Mass in Patients With Ischemic Heart Disease
Cardiovascular disease is the most common cause of death in the world. Most of the attention in treating ischemic heart disease (IHD) is understandably directed toward treating coronary artery disease.
- Trial name
- NCT01879293
- Testing
- Metformin
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Wuhan General Hospital of Guangzhou Military Command
Atrial Flutter
Cardiovascular Magnetic Resonance-Guided Radiofrequency-Ablation for Atrial Flutter II
The purpose of this clinical study is to assess the safety and performance of the Vision-MR Ablation Catheter, the primary safety endpoint will measure the rate of serious adverse events related to the device or procedure; the…
- Trial name
- 2016-IMR (NCT03078985)
- Testing
- ablation for typical atrial flutter, catheter ablation with study device
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- University of Leipzig
Sudden Cardiac Death, Sudden Cardiac Arrest
Low QRS Voltages in Young Healthy Individuals and Athletes
There is some limited evidence that reduced size of electrical complexes/traces of the heart on the electrocardiogram (ECG) may be associated with scarring in the heart muscle, which may predispose to serious life-threatening…
- Conditions
- Sudden Cardiac Death, Sudden Cardiac Arrest, Sudden Cardiac Death Due to Cardiac Arrhythmia, Arrhythmogenic Right Ventricular Cardiomyopathy
- Trial name
- NCT05799833
- Testing
- Cardiovascular magnetic resonance scan - 3T scanner (Siemens Vida)
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Atrial Fibrillation
DECAAF: Delayed-Enhancement MRI (DE-MRI) Determinant of Successful Radiofrequency Catheter Ablation of Atrial Fibrillation
This is a multi-center, observational, 1-year prospective cohort study (1 year follow-up, at 3, 6 and 12 month) with approximately 675 participants.
- Trial name
- DECAAF (NCT01150214)
- Testing
- DE-MRI
- Where
- 15 sites in United States, Australia and 5 more
- Volunteers
- 339 people
- Sponsor
- University of Utah
ST Elevation Myocardial Infarction, Remodeling, Left Ventricle
Predictors of Adverse Left Ventricular Remodeling and Final Infarct Size After Primary Percutaneous Coronary Intervention for ST Elevation Myocardial Infarction: A Strain Analysis Study Using Echocardiography and Feature Tracking Cardiac Magnetic Resonance
ST-segment elevation myocardial infarction (STEMI) is one of the most important causes of death and disability around the world.
- Trial name
- NCT04773652
- Testing
- speckle tracking echo
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Aortic Stenosis
The Role of Myocardial Fibrosis in Patients With Aortic Stenosis
Aortic stenosis is the most common adult valvular heart disease in the western world. Heart failure and sudden cardiac death are complications associated with aortic stenosis.
- Trial name
- NCT01755936
- Testing
- Cardiac Magnetic Resonance Imaging, Echocardiography, 72 hour Holter Monitor
- Where
- United Kingdom
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Coronary Disease
Safety and Effectiveness of Coronary Magnetic Resonance Angiography (CMRA) Imaging
Magnetic resonance imaging (MRI) is a diagnostic tool that creates high quality images of the human body without the use of X-ray (radiation).
- Trial name
- NCT00001633
- Testing
- Coronary magnetic resonance angiography imaging
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Sudden Cardiac Death Due to Cardiac Arrhythmia, Dilated Cardiomyopathy
Arrhythmic Risk Stratification in Nonischemic Dilated Cardiomyopathy
Nonischemic dilated cardiomyopathy is a heterogeneous disease often associated with increased rates of sudden cardiac death. Although many algorithms have been proposed, risk stratification remains suboptimal, and implantable…
- Trial name
- ReCONSIDER (NCT04246450)
- Testing
- Implantable Cardioverter Defibrillator (ICD) insertion
- Where
- Greece
- Volunteers
- 675 people
- Sponsor
- University of Athens
Magnetic Resonance Imaging (MRI), Cardiac Pacing
Evaluation of Approved Pacing Lead (Model 5076) for Use in MRI Environment
The purpose of this study is to test the safety and effectiveness of the Medtronic CapSureFix Novus Model 5076 lead when patients are implanted with the Medtronic Advisa MRI pacemaker and undergo an MRI scan.
- Trial name
- NCT01755143
- Testing
- Magnetic Resonance Imaging scan sequences of the head, neck, and chest, Pacemaker System
- Where
- 36 sites in Australia, Austria and 17 more
- Volunteers
- 266 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Myocardial Infarction
Myocardial Oedema in Acute Myocardial Infarction (AMI)
Despite recent improvements in treatment, myocardial infarction (heart attack) is still a leading cause of illness and death in the UK.
- Trial name
- NCT00987259
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Barts & The London NHS Trust
ST Segment Elevation Myocardial Infarction, Myocardial Oedema
Myocardial Oedema in ST Segment Elevation Myocardial Infarction Myocardial
Cardiac magnetic resonance imaging (CMR) is a non invasive technique used to obtain functional and anatomical information on the heart.
- Trial name
- NCT01897350
- Testing
- Cardiac magnetic resonance imaging
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Elisa McAlindon
Arrhythmias, Cardiac
Safety of Magnetic Resonance Imaging in Non-MRI Conditional Pacemakers and ICD Devices
The primary objective of the study is to determine the safety of MRI in patients with non-MRI conditional pacemakers. The secondary objective is to determine if there are clinically relevant parameter changes in the devices.
- Trial name
- NCT02906189
- Testing
- MRI
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Banner Health
Diastolic Dysfunction
Diastolic Function Assessment With Cardiac Magnetic Resonance Imaging
Cardiac magnetic resonance (CMR) imaging is excellent at assessing the contractility of the heart muscle. However, relatively little is known about CMR's ability to assess the relaxation (diastolic function) of the heart between…
- Trial name
- DIAMER (NCT05438030)
- Testing
- Cardiac MRI scan, Echocardiogram scan
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- Imperial College London
Acute Myocardial Infarction
Ischemic Time and Extent of Myocardial Infarction (MI) With Cardiac Magnetic Resonance Imaging (CMRI) in Patients With ST Elevation Myocardial Infarction (STEMI) and Primary Percutaneous Coronary Intervention (PCI) Study
This study will assess relationship between ischemic time and the extent of myocardial infarction with cardiac magnetic resonance image in patients with STEMI (ST elevation myocardial infarction) and primary percutaneous coronary…
- Trial name
- ITEMMRI (NCT01401881)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Medstar Health Research Institute
Cardiovascular Disease
Technical Development of Cardiovascular Magnetic Resonance Imaging
Background: In the U.S., over 6.5 million people have heart failure. Researchers want to develop new testing methods for cardiovascular problems using magnetic resonance imaging (MRI) to improve the clinical diagnosis and…
- Trial name
- NCT04927429
- Where
- 2 sites in United States
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiac Magnetic Resonance
Assessment of Left Atrial Size and Function by Cardiac Magnetic Resonance
Left atrial (LA) size and function are powerful prognostic markers in a variety of clinical conditions. Cardiac magnetic resonance (CMR) is considered the gold-standard to assess the volumes of heart chambers by contouring cavity…
- Trial name
- ALATRIUM (NCT07561151)
- Testing
- CMR scan
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituto Auxologico Italiano
Myocarditis
Magnetic Resonance Imaging in Myocarditis
The purpose of this study is the assess the diagnostic performance of magnetic resonance imaging in patients with suspected myocarditis by applying different imaging sequences at different MR scanners
- Trial name
- MyoRacer (NCT02177630)
- Testing
- Endomyocardial Biopsy
- Where
- Germany
- Volunteers
- 129 people
- Sponsor
- Heart Center Leipzig - University Hospital
Hibernation, Myocardial, Complete Occlusion of Coronary Artery
The Success of Opening Single CTO Lesions to Improve Myocardial Viability Study (SOS-comedy)
The purpose of this study is to investigate the effect of percutaneous coronary intervention (PCI) on myocardial viability in coronary artery disease patients with single coronary total occlusion (CTO) lesions.
- Trial name
- NCT02767401
- Testing
- stenting or balloon expansion, aspirin, clopidogrel, ticagrelor, atorvastatin, rosuvastatin, betaloc
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Microvascular Obstruction (MVO), Multivessel Coronary Artery Disease
For Patients With Myocardial Infarction and Multiple Vessel: Testing if Ultrasound (UFR) Can Guide All Needed Treatment in One Procedure, Avoiding a Return Hospital Visit for a Second Operation.
Brief Summary The Purpose of the Study : The purpose of this study is to find a safe and reliable "one-stop" solution for treating heart attack patients who have multiple blocked arteries.
- Conditions
- Microvascular Obstruction (MVO), Multivessel Coronary Artery Disease, ACS (Acute Coronary Syndrome), ST Elevation Myocardial Infarction (STEMI)
- Trial name
- ACT-EVOLVE (NCT07264881)
- Testing
- IVUS-based Fractional Flow Reserve (UFR), Invasive Coronary Physiology Measurement (FFR/RFR/IMR), Cardiac Magnetic Resonance (CMR)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Anzhen Hospital