Clinical trials: Cardiac Magnetic Resonance
Myocarditis, Cardiomyopathy, Dilated
French National Observatory Tracking Viral Myocarditis: Mortality, Cardiovascular Events, Sequels on (Magnetic Resonance Imaging) MRI
Acute myocarditis is a serious illness affecting a young population with a very variable course (of full recovery at the onset of dilated cardiomyopathy (DCM), or even sudden death).
- Conditions
- Myocarditis, Cardiomyopathy, Dilated, Magnetic Resonance Imaging
- Trial name
- MYOCARDITIRM (NCT02717143)
- Where
- France
- Volunteers
- 821 people
- Sponsor
- French Cardiology Society
Anxiety, Claustrophobia
Evaluation of an MRI-compatible Vital Signs Sensor System
This study is to determine the possibility of assessing the level of anxiety in MRI patients by means of the respiration rate (RR) and heart rate (HR) indicators acquired by a fiber-optic sensor system.
- Conditions
- Anxiety, Claustrophobia, Hyperventilation, Stress
- Trial name
- OPTO-MRI (NCT03384849)
- Testing
- MRI examination
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Military Institute of Aviation Medicine
Cardiac Diseases
Non-Invasive Determination of Cardiac Output by Electrical Velocimetry
The cardiac output (CO) is an important parameter in the diagnosis and therapy of cardiac diseases. The current standard methods for the determination of the CO, however, are either invasive (e.g.
- Trial name
- NCT00945048
- Testing
- electrical velocimetry, inert gas rebreathing, spirometry
- Where
- Germany
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Kawasaki Disease, Heart Disease
Real Time Myocardial Contrast Echocardiography and Dobutamine Stress Perfusion Magnetic Resonance Imaging
The present study is designed to: 1. investigate the safety and efficacy of Real time myocardial echocardiography (RT-MCE) in adolescents and adults ages 12-50 with congenital and acquired congenital heart disease 2.
- Trial name
- ECHOBIKE (NCT00861848)
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Cardiac Magnetic Resonance, T1 Mapping
Normal Variation of T1 Values With Cardiac Magnetic Resonance in Healthy Individuals
The purpose of the study is to determine the normal variation of T1 values with cardiac magnetic resonance in healthy individuals with respect to reproducibility, changes over time, and dependency on hydration status.
- Conditions
- Cardiac Magnetic Resonance, T1 Mapping, Healthy Individuals
- Trial name
- NATIVE (NCT05597657)
- Testing
- Fluid administration (Fresenius Kabi Sodium Chloride 0.9%)
- Where
- Denmark
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Abandoned Endocardial Leads, Broken Endocardial Leads
Diagnostic Utility of Cardiac MRI
This is a prospective cohort study looking to systematically evaluate the safety of conducting cardiac Magnetic Resonance Imaging (MRI) in this high-risk patient group with abandoned, fractured endocardial leads or surgically…
- Conditions
- Abandoned Endocardial Leads, Broken Endocardial Leads, Permanent Epicardial Leads
- Trial name
- NCT07679009
- Testing
- Cardiac MRI (CMR)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor Research Institute
Heart Failure With Preserved Ejection Fraction (HFPEF), Renal Dysfunction
Determination of the Prevalence of Unrecognized Heart Failure Among Patients at Risk in Urban Areas Across Germany Using CMR
Heart failure (HF) in patients at risk is often overlooked, and when detected, there is a lack of early and effective preventive interventions.
- Conditions
- Heart Failure With Preserved Ejection Fraction (HFPEF), Renal Dysfunction, Stage B Heart Failure
- Trial name
- WE-CARE-HF-CMR (NCT07185100)
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- German Heart Institute
Dilated Cardiomyopathy, Thrombosis Cardiac
Intraventricular Stasis In Cardiovascular Disease
This study is designed to quantify the ventricular stasis in patients with different forms of cardiomyopathy and at risk of stroke (ischemic, non-ischemic dilated cardiomyopathy and hypertrophic cardiomyopathy) by post-processing…
- Conditions
- Dilated Cardiomyopathy, Thrombosis Cardiac, Stroke, Hypertrophic Cardiomyopathy
- Trial name
- ISBIFLOW (NCT04649034)
- Testing
- Doppler echocardiogram exam, Cardiac magnetic resonance, Brain magnetic resonance
- Where
- 3 sites in Spain
- Volunteers
- 258 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
ST Elevation Myocardial Infarction
Prasugrel vs. Ticagrelor on Myocardial Injury in STEMI
The investigators propose to perform a randomized clinical trial comparing prasugrel vs. ticagrelor in 60 patients with ST elevation acute myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention.
- Trial name
- COMPARE (NCT03435133)
- Testing
- Prasugrel, Ticagrelor
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- AORTICA Group
COVID-19, Myocarditis
Clinical Significance of Subclinical Myocardial Involvement in Recovered COVID-19 Patients Using Cardiovascular Magnetic Resonance
Introduction: Coronavirus disease 2019 (COVID-19) remains a major health issue resulting in >800,000 deaths as of 30th August 2020. A concerning discovery of COVID-19 is the involvement of the myocardium.
- Trial name
- R-COVID-CMR (NCT05184114)
- Testing
- Cardiac Magnetic Resonance, Blood Tests
- Where
- Hong Kong
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Ischemic Left Ventricle Systolic Dysfunction, Multivessel Coronary Artery Disease
STICH3C Cardiac Magnetic Resonance Observational Study
STICOS will test the hypothesis that residual jeopardized myocardium, late gadolinium enhancement, and non-ischemic substrate after revascularization is associated with postoperative adverse cardiovascular events such as heart…
- Trial name
- STICOS (NCT07133984)
- Testing
- Cardiac Magnetic Resonance Imaging
- Where
- 10 sites in United States, Austria and 4 more
- Volunteers
- 230 people
- Sponsor
- Weill Medical College of Cornell University
Stable Coronary Artery Disease, Cardiac Magnetic Resonance Imaging
Magnetic Resonance Adenosine Perfusion Imaging as Gatekeeper of Invasive Coronary Intervention
Current guidelines for the diagnosis and management of patients with stable coronary artery disease (CAD) strongly support the performance of non-invasive imaging techniques for the detection of myocardial ischemia prior to…
- Conditions
- Stable Coronary Artery Disease, Cardiac Magnetic Resonance Imaging, Coronary Angiography, Myocardial Revascularization
- Trial name
- MAGnet (NCT02580851)
- Testing
- diagnostic test - cardiac magnetic resonance imaging, diagnostic test - coronary angiography
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Ulm
Heart Failure, Myocardial Infarct
Observational Study of the Remodelling Process Following Myocardial Infarct
This study will assess the relationship between collagen turnover, neurohormonal activation, scarring and left ventricle remodelling in patients 3 years following a myocardial infarction.
- Trial name
- NCT00338156
- Where
- Norway
- Volunteers
- 119 people
- Sponsor
- Helse Stavanger HF
ST-segment Elevation Myocardial Infarction (STEMI)
Angio-IMR and Cardiac MR-derived MVO in STEMI Patients
Coronary microcirculatory dysfunction has been known to be prevalent even after successful revascularization of ST-segment elevation myocardial infarction (STEMI) patients.
- Trial name
- NCT04828681
- Testing
- Cardiac magnetic resonance imaging
- Where
- 2 sites in United States, China
- Volunteers
- 324 people
- Sponsor
- Samsung Medical Center
Myocardial Infarction, Death, Sudden, Cardiac
Effect of High Dose Fish Oil Supplementation After Recent Heart Attack Using Magnetic Resonance Imaging
Doctors use magnetic resonance imaging (MRI) to obtain detailed pictures of the inside of the body. This study will evaluate a new MRI technique in people who have recently had a heart attack.
- Trial name
- OmegaREMODEL (NCT00729430)
- Testing
- Omega-3 Fatty Acids (Fish Oil Supplements)
- Where
- United States
- Volunteers
- 358 people
- Sponsor
- Brigham and Women's Hospital
Atrial Fibrillation
Does the Merged 3D Imaging Improve Contact Force and Long Term Procedure Outcome in Atrial Fibrillation?
The purpose of the study is to investigate whether or not there are the differences in acute procedure and long-term clinical outcome of radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF) using the 3D map…
- Trial name
- MICRO-AF (NCT03350581)
- Testing
- FAM 3D map group, FAM-CT 3D map group
- Where
- 2 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Korea University Guro Hospital
ISCHEMIC CARDIOMYOPATHY
Clinical Trial of Manganese-Enhanced MRI (MEMRI) to Assess Peri-Infarct Injury
The purpose of this study is to evaluate the safety and tolerance of a new intravenous diagnostic agent, SeeMore or EVP 1001-1, in patients with Cardiovascular Disease (MEMRI scan).
- Trial name
- NCT02933034
- Testing
- Manganese-enhanced MRI contrast reagent, Gadolinium-enhanced MRI contrast reagent
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Stanford University
Recurrent Pericarditis
Therapy Management in Patients Treated With Anakinra Due to Recurrent Pericarditis
To determine the utility of serial cardiac magnetic resonance (CMR) imaging for guidance of therapy management in patients treated with anakinra due to recurrent pericarditis (RP), compared with c-reactive protein (CRP) assay…
- Trial name
- NCT06071156
- Testing
- Anakinra
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliero, Universitaria Ospedali Riuniti
Aortic Stenosis, Calcific
Prognostic Value of Myocardial Fibrosis in Severe Aortic Valve Stenosis
Degenerative aortic valve stenosis (AS) is the most common valve heart disease in the developed Western countries. The hemodynamic progression of AS occurs over time and leads to LV hypertrophy (LVH) as a compensation mechanism…
- Trial name
- FIB-AS (NCT03585933)
- Testing
- Cardiac magnetic resonance imaging
- Where
- 2 sites in Denmark, Lithuania
- Volunteers
- 110 people
- Sponsor
- Vilnius University
Pediatric Heart Transplant
Non-invasive Detection of Acute Cell-mediated Graft Rejection in Pediatric Heart Transplant Recipients
Acute cardiac rejection is currently diagnosed by endomyocardial biopsy (EMB), but multiparametric cardiac magnetic resonance (CMR) may be a non-invasive alternative by its capacity for myocardial structure and function…
- Trial name
- NCT06795958
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna