Clinical trials: Cardiac Magnetic Resonance
Arteriosclerosis, Diabetes Mellitus
A High-Resolution Magnetic Resonance Imaging Study to Evaluate the Effect of Rosuvastatin on Carotid Atherosclerotic Plaques
The aim of this study is to assess whether high intensive statin therapy could regress carotid atherosclerotic plaques as determined by High-Resolution Contrast Enhanced Magnetic Resonance imaging (CE-MRI).
- Conditions
- Arteriosclerosis, Diabetes Mellitus, Lipid Disorder
- Trial name
- NCT02305862
- Testing
- Rosuvastatin 5mg, Rosuvastatin 20mg
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Capital Medical University
Ischemic Heart Disease
Myocardial Perfusion Imaging by Combined 15O-H2O PET and MR
The trial will include 75 patients with evident or suspected ischemic heart disease refered to Department of Nuclear Medicine \& PET Centre, Aarhus University Hospital, for perfusion imaging by 15O-H2O PET/CT scan of the heart…
- Trial name
- PREFER (NCT04940247)
- Where
- Denmark
- Volunteers
- 73 people
- Sponsor
- University of Aarhus
Myocardial Infarction, Angina, Unstable
Using Magnetic Resonance Imaging to Evaluate Heart Vessel Function After Angioplasty or Stent Placement Procedures
Coronary artery disease (CAD) is caused by a narrowing of the blood vessels that supply blood and oxygen to the heart. Balloon angioplasty and stent placement are two treatment options for people with reduced heart function…
- Conditions
- Myocardial Infarction, Angina, Unstable, Cardiomyopathy, Hypertrophic
- Trial name
- NCT00692991
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Johns Hopkins University
Primary Hyperaldosteronism, Secondary Hyperaldosteronism
Study of Myocardial Interstitial Fibrosis in Hyperaldosteronism
Animal models have demonstrated the role of aldosterone in left ventricular remodeling involving fibrosis, apoptosis and hypertrophy.
- Conditions
- Primary Hyperaldosteronism, Secondary Hyperaldosteronism, Essential Hypertension, Healthy
- Trial name
- COEURALDO (NCT02938910)
- Testing
- non interventional study
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anorexia Nervosa, Cardiac Anomaly
Evaluation of CARdiac Abnormalities by Echocardiography and MRI in Malnourished Patients Suffering From Anorexia Nervosa
Anorexia nervosa is an eating disorder occurring in adolescent females, characterized by voluntary dietary restriction, intense fear of gaining weight, and disturbed body image perception.
- Trial name
- CARERA (NCT03600610)
- Testing
- gadolinium-enhanced cardiac MRI
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Cardiomyopathies
Effects of Renal Transplantation on Uraemic Cardiomyopathy
Chronic kidney disease (CKD) is associated with a high risk of death and morbidity due to cardiovascular disease. Much of this is caused by left ventricular disease characterised by abnormal muscle thickness and scaring.
- Trial name
- RETRACT (NCT03892343)
- Testing
- Cardiac MRI
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Right Ventricular Dysfunction
Right Ventricular Function Changes After CIED Implantation: The RIGHT-CIED Study
This study aims to understand how the right side of the heart changes in people who receive an implantable cardiac electronic device (CIED), such as a pacemaker, ICD, or CRT device.
- Trial name
- RIGHT-CIED (NCT07272395)
- Testing
- Multimodal Right Ventricular Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
Heart Disease
Prevalence of Delirium in Patients Undergoing Cardiac Surgery
The objective of this study is to determine prevalence of postoperative delirium and confusion in patients undergoing cardiac surgery.
- Trial name
- NCT00242151
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Atrial Fibrillation
Consistency of LGE-MRI Fibrosis and EAM Low-voltage Area
This study aims to: 1. Assess the consistency of LGE-MRI bi-atrial fibrosis and electroanatomical mapping of bi-atrial low voltage region 2.
- Trial name
- NCT06552845
- Testing
- LGE-MRI Scan
- Where
- China
- Volunteers
- 50 people
- Sponsor
- China National Center for Cardiovascular Diseases
Myocardial Ischemia
Cardiac Magnetic Resonance Utilities in the Evaluation of Ischemic Heart Disease
The purpose of this study is to evaluate CARDIAC MAGNETIC RESONANCE UTILITIES IN THE ISCHEMIC HEART DISEASE as topographical correlation between ischemic territory injury and coronary angiography.
- Trial name
- CARDIO-RM (NCT01397357)
- Testing
- Cardiac magnetic resonance - CINE MRI stress test.
- Where
- Italy
- Volunteers
- 146 people
- Sponsor
- Ettore Sansavini Health Science Foundation
Atrial Fibrillation, Thrombosis
Association of Genetic Polymorphisms With Atrial Fibrosis and Thrombogenic Substrate in Patients With Non-valvular Atrial Fibrillation
Atrial fibrillation (AF) is the most frequently encountered cardiac arrhythmia. Emerging data suggests that common genetic variants are associated with the development of AF.
- Conditions
- Atrial Fibrillation, Thrombosis, Stroke, Genetic Predisposition
- Trial name
- ANATOLI-AF (NCT03560219)
- Testing
- Biomarkers, Cardiac Magnetic Resonance Imaging, Echocardiography, Flow Mediated Dilatation, Genetic Analysis
- Volunteers
- 225 people
- Sponsor
- Memorial Ankara Hospital
Acute Myocardial Infarction
Ischemic Time and Extent of Myocardial Infarction (MI) With Cardiac Magnetic Resonance Imaging (CMRI) in Patients With ST Elevation Myocardial Infarction (STEMI) and Primary Percutaneous Coronary Intervention (PCI) Study
This study will assess relationship between ischemic time and the extent of myocardial infarction with cardiac magnetic resonance image in patients with STEMI (ST elevation myocardial infarction) and primary percutaneous coronary…
- Trial name
- ITEMMRI (NCT01401881)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Medstar Health Research Institute
Heart Failure, Cardiomyopathies
Towards Understanding the Phenotype of Cardiovascular Disease in CKD - TRUE-Type-CKD Study
Premature cardiovascular disease (CVD) is the leading cause of death in patients with kidney disease (CKD). Excessive cardiac mortality is thought to be secondary to non-atherosclerotic processes, with left ventricular (LV)…
- Conditions
- Heart Failure, Cardiomyopathies, Chronic Kidney Diseases, Hypertrophy, Left Ventricular
- Trial name
- TRUE-TypeCKD (NCT03749551)
- Testing
- cardiac magnetic resonance (CMR) post haemodialysis
- Where
- Germany
- Volunteers
- 276 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Non Ischemic Cardiomyopathy
Magnetic Resonance Imaging Based Risk Stratification for Defibrillator Implantation in Heart Failure Patients Requiring Cardiac Resynchronisation Therapy
This randomized study aimed to compare the efficacy of LBBP without defibrillator vs biventricular pacing with defibrillator (BiV-ICD/CRT-D) in patients with LB-NICM and left ventricular ejection fraction (LVEF) ≤35% risk…
- Trial name
- MADURAI CRT (NCT07791407)
- Testing
- left bundle branch pacing, Biventricular pacing with defibrillator
- Where
- India
- Volunteers
- 114 people
- Sponsor
- Velammal Medical College Hospital and Research Institute
Ischaemic Cardiomyopathy, Non-ischaemic Cardiomyopathy
Profitability Trial in Primary Preventive Implantable Cardioverter-defibrillator Recipients
The purpose of this study is further risk stratification of patients receiving implantable cardioverter-defibrillator in primary prevention of sudden cardiac death.
- Trial name
- HAPPIER (NCT01823211)
- Where
- 3 sites in Czechia
- Volunteers
- 50 people
- Sponsor
- University Hospital Ostrava
Atrial Fibrillation, Atrial Arrhythmia
Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
The study aims to evaluate and compare the incidence of atrial arrhythmias (including Post-Operative Atrial Fibrillation (POAF), atrial flutter, and atrial tachycardia) stratified by baseline Utah fibrosis stages and overall…
- Conditions
- Atrial Fibrillation, Atrial Arrhythmia, Atrial Flutter, Atrial Tachycardia
- Trial name
- NCT05014802
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Tulane University
Connective Tissue Diseases, Right Ventricular Hypertrophy
Early Detection of Cardiac Impairment and Prediction of RV Hypertrophy in Patients With CTD
There have been reports suggesting that progressive RV failure and death in connective tissue disease (CTD) are related to right ventricular hypertrophy (RVH) and dilation, irrespective of pulmonary arterial hypertension (PAH).
- Trial name
- EARLY-MYO-CTD (NCT04297371)
- Testing
- CMR examination
- Where
- China
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Kidney Failure, Chronic
Left Ventricular Hypertrophy and Spironolactone in End Stage Renal Disease
The hypothesis of this trial is to assess the effect of spironolactone on heart size and mass
- Trial name
- NCT00548912
- Testing
- Spironolactone
- Where
- United States
- Sponsor
- Dawnmarie DeFazio
Metabolic Syndrome, Coronary Microvascular Dysfunction
Vericiguat in Patients With Metabolic Syndrome and Coronary Vascular Dysfunction
Coronary vascular dysfunction is one of the "final common pathways" for the impact of multiple cardiovascular risk factors. The investigators will conduct a randomized, double-blind placebo-controlled study in individuals with…
- Trial name
- NCT05711719
- Testing
- Vericiguat
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Johns Hopkins University
Cardiomyopathy, Hypertrophic Cardiomyopathies
French Registry: Late Gadolinium Enhancement in Hypertrophic Cardiomyopathy
This study aims to create a registry of patients with hypertrophic cardiomyopathy, a condition characterized by excessive thickening of the heart muscle. This disease can sometimes lead to serious complications.
- Trial name
- HCM-LGE (NCT07428031)
- Volunteers
- 5,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris