Clinical trials: Cardiac Magnetic Resonance
Atrial Flutter
Radio Frequency Ablation for Atrial Flutter With Magnetic Resonance Guidance and Tracking
The Radio Frequency Ablation for Atrial Flutter with Magnetic Resonance Guidance and Tracking Pilot Study (hereafter referred to as "pilot study") is a prospective, non- randomized, single-center, pilot study.
- Trial name
- NCT02380937
- Testing
- ablation for typical atrial flutter, Vision Ablation Catheter
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- University of Leipzig
Chest Pain, Myocardial Infarction
The Supplementary Role of Non-invasive Imaging to Routine Clinical Practice in Suspected Non-ST-elevation Myocardial Infarction
Approximately half of patients with acute chest pain, a very common reason for emergency department visits worldwide, have a cardiac cause.
- Conditions
- Chest Pain, Myocardial Infarction, Acute Coronary Syndrome, Coronary Artery Disease
- Trial name
- CARMENTA (NCT01559467)
- Testing
- Cardiovascular Magnetic Resonance Imaging, Computed Tomography Angiography
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Maastricht University Medical Center
Cardiac Magnetic Resonance
Assessment of Left Atrial Size and Function by Cardiac Magnetic Resonance
Left atrial (LA) size and function are powerful prognostic markers in a variety of clinical conditions. Cardiac magnetic resonance (CMR) is considered the gold-standard to assess the volumes of heart chambers by contouring cavity…
- Trial name
- ALATRIUM (NCT07561151)
- Testing
- CMR scan
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituto Auxologico Italiano
Acute ST-elevation Myocardial Infarction
Detection and Significance of Heart Injury in ST Elevation Myocardial Infarction.
Heart imaging with magnetic resonance imaging (MRI) provides detailed insights into heart function and injury. The nature and significance of heart injury after a heart attack is incompletely understood.
- Trial name
- BHF MR-MI (NCT02072850)
- Testing
- Coronary pressure wire, Magnetic resonance imaging of the heart
- Where
- United Kingdom
- Volunteers
- 324 people
- Sponsor
- NHS National Waiting Times Centre Board
Coronary Artery Disease, Carotid Artery Diseases
Evaluate Carotid Artery Plaque Composition by Magnetic Resonance Imaging in People Receiving Cholesterol Medication
Atherosclerosis is a condition that occurs when fatty deposits build up along the inner walls of arteries. This study will examine the effectiveness of a combination of cholesterol-lowering medications at decreasing the fat…
- Conditions
- Coronary Artery Disease, Carotid Artery Diseases, Atherosclerosis
- Trial name
- CPC (NCT00715273)
- Testing
- Atorvastatin, Niacin, Colesevelam
- Where
- 4 sites in United States
- Volunteers
- 217 people
- Sponsor
- University of Washington
Pulmonary Hypertension
PH-DyPred: A Multimodal Dynamic Risk Prediction Study in Pulmonary Hypertension
Pulmonary hypertension (PH) is a progressive cardiopulmonary disease characterized by elevated pulmonary artery pressure and vascular remodeling, which leads to right heart failure and increased mortality.
- Trial name
- PH-DyPred (NCT07131241)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Atrial Fibrillation
Swiss Atrial Fibrillation Cohort Study
Swiss-AF is a prospective observational, multicentric cohort study in Switzerland. Overall, 2600 patients with documented atrial fibrillation aged >65 years will be included and followed on a yearly basis.
- Trial name
- SWISS-AF (NCT02105844)
- Where
- Switzerland
- Volunteers
- 2,415 people
- Sponsor
- University Hospital, Basel, Switzerland
Heart Failure, Diastolic, Diastolic Heart Failure
Myocardial Perfusion, Oxidative Metabolism, and Fibrosis in HFpEF
Unlike heart failure with reduced ejection fraction (HFrEF) where several medicines and devices have been demonstrated to reduce mortality, no such therapies have been identified in HFpEF.
- Conditions
- Heart Failure, Diastolic, Diastolic Heart Failure, Hypertension
- Trial name
- HFpEF-PRoF (NCT02589977)
- Testing
- regadenoson
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Marvin W. Kronenberg, M.D.
Acute Coronary Syndrome
Ticagrelor Versus Clopidogrel in Myocardial Salvage in Patients With STEMI Undergoing Primary PCI
Therefore, in this study, we try to evaluate the impact of clopidogrel loading dose 300mg vs. ticagrelor 180 mg on myocardial injury as measured by contrast-enhanced magnetic resonance imaging (CE-MRI) in STEMI patients…
- Trial name
- NCT02792712
- Testing
- Ticagrelor, Clopidogrel
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Pacemakers, MRI Imaging
The MagnaSafe-2 Registry: Assessing the Risks of Magnetic Resonance Imaging in Three Patient Groups
SUMMARY OF THE CLINICAL PROTOCOL Background: The risks of Magnetic Resonance Imaging (MRI) at 1.5-tesla for patients with a non-MRI-conditional (NMRC) pacemaker have been documented, guidelines for clinical practice have been…
- Conditions
- Pacemakers, MRI Imaging, Implantable Cardioverter Defibrillator (ICD)
- Trial name
- NCT07189728
- Testing
- MRI
- Volunteers
- 1,500 people
- Sponsor
- The Scripps Research Institute
Coronary Artery Disease
Multicenter Myocardial Viability Trial
The purpose of this study is to test the hypothesis of whether contrast enhanced Magnetic Resonance Imaging can be used to predict improvement of the wall motion in regions of the heart with abnormal movement following bypass…
- Trial name
- NCT00661232
- Where
- 7 sites in United States, Belgium and 4 more
- Volunteers
- 235 people
- Sponsor
- CHI St. Luke's Health, Texas
Coronary Artery Disease, Human Immunodeficiency Virus (HIV)
Pericardial Fat and Inflammation in HIV Patients and Controls
The investigators propose to correlate 1) cardiac MRI pericardial adipose volume, 2) the presence of pericardial monocytes and 3) circulating immune biomarkers in persons with and without CHD and HIV infection compared to…
- Trial name
- NCT02399384
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Cincinnati
Magnetic Resonance Angiography
Comparison of Magnetic Resonance Coronary Angiography (MRCA) With Coronary Computed Tomography Angiography (CTA)
Magnetic resonance coronary angiography (MRCA) has its advantage in its ability to assess the coronary artery morphology without radiation or contrast media.
- Trial name
- NCT03768999
- Testing
- Non-contrast magnetic resonance coronary angiography (MRCA)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Johns Hopkins University
Acute Myocardial Infarction
Clinical Implication CMR in AMI Registry
1. To evaluate the clinical implication of cardiac magnetic resonance imaging in patients with acute myocardial infarction 2. To determine factors affecting the 6-month remodeling index assessed by cardiac magnetic resonance…
- Trial name
- CMR-AMI (NCT04788940)
- Testing
- Percutaneous Coronary Intervention
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Samsung Medical Center
Chemotherapy Induced Cardiotoxicity
Cardiac Magnetic Resonance for Early Detection of Chemotherapy or Radiation Therapy Induced Cardiotoxicity in Breast Cancer (CareBest)
Chemotherapy or radiation therapy-induced cardiotoxicity are well-recognized side effects in patients with cancer. The clinical significance of cardiotoxicity is growing with increasing cancer survivor-ship.
- Trial name
- NCT03301389
- Testing
- Cardiac magnetic resonance imaging
- Where
- South Korea
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Cardiovascular Disease
Heart Attack Prevention Programme for You (HAPPY) London
Diseases of the heart and blood vessels, such as heart attacks and strokes, are very common and can lead to severe disability or death.
- Trial name
- HAPPYLondon (NCT01911910)
- Testing
- Electronic coaching plus standard care
- Where
- United Kingdom
- Volunteers
- 402 people
- Sponsor
- Queen Mary University of London
Ventricular Tachycardia, Cardiac Arrhythmia
MRI Assessment of Arrythmia Ablation Lesions
This study will evaluate the feasibility of visualization and characterization of arrhythmia ablation lesions by MRI immediately following standard ablation techniques.
- Trial name
- NCT02761343
- Testing
- MRI scan
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Children's National Research Institute
Cardiac Graft
Acute Heart Graft Rejection Screening by Cardiac Magnetic Resonance Imaging
Acute heart allograft rejection is a common complication after orthotopic heart transplantation. Primary objective of this study is to assess cardiac MRI as a tool for acute heart graft rejection screening, by detecting changes…
- Trial name
- DRAGON (NCT02400840)
- Testing
- cardiac MRI, gadobenic acid intravenous injection 0.2 ml/kg
- Where
- France
- Sponsor
- University Hospital, Rouen
Cardiomyopathies, Amyloidosis Cardiac
Characterization of Patients With Cardiomyopathy to Identify Critical Patients Candidates for Cardiac Transplantation
The study aims to identify new diagnostic and prognostic markers for CMP that can help predict disease progression. In particular, the study will focus on microRNAs (miRNAs) and spatial transcriptomics, which are emerging…
- Conditions
- Cardiomyopathies, Amyloidosis Cardiac, Fabry Disease, Arrhythmogenic Cardiomyopathy
- Trial name
- CMPMIRNA (NCT06813443)
- Where
- 3 sites in Italy
- Volunteers
- 700 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Heart Valve Disease, Ventricular Function
Magnetic Resonance Imaging and Fibrosis
Aortic valve disease causes impaired let ventricular function (LVF) due to hypertrophy, dilatation and diffuse myocardial fibrosis yet the prognostic effect of fibrosis, waiting time for operation and postoperative exercise…
- Conditions
- Heart Valve Disease, Ventricular Function, Fibrosis
- Trial name
- MRF (NCT02790008)
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Linkoeping University