Clinical trials: Cardiac Output, Low
Low Cardiac Output Syndrome
Patients With Low Cardiac Output Syndrome Undergoing Local Dental Anesthesia
Patients with low cardiac output syndrome requiring surgical and periodontal dental treatment will be selected to undergo the dental procedure using local dental anesthetic: 2% lidocaine with epinephrine and 2% lidocaine without…
- Trial name
- NCT06355882
- Testing
- Anesthetic infiltration
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Sao Paulo General Hospital
End Stage Renal Failure on Dialysis, Body Fluid Retention
Changes in Volumetric Hemodynamic Parameters Induced by Fluid Removal on Hemodialysis
Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 …
- Conditions
- End Stage Renal Failure on Dialysis, Body Fluid Retention, Impedance, Cardiac Output, Low
- Trial name
- CI/HD (NCT02485782)
- Testing
- CardioScreen 1000 - Haemodynamic Measurement System, Medis, BCM- Body Composition Monitor, Fresenius Medical Care, SCHILLER, BR-102 plus, Ambulatory Blood Pressure Monitoring System
- Where
- Poland
- Volunteers
- 48 people
- Sponsor
- Medical University of Warsaw
Cardiopulmonary Failure, Myocardial Infarction (MI)
COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable
The COR-INSIGHT trial aims to evaluate the effectiveness of Peerbridge COR advanced ambulatory ECG wearables (COR 1.0 and COR 2.0) in accurately and non-invasively detecting cardiovascular and cardiopulmonary conditions using…
- Conditions
- Cardiopulmonary Failure, Myocardial Infarction (MI), Heart Decompensation, Heart Failure
- Trial name
- COR-INSIGHT (NCT06763549)
- Testing
- SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc
Cardiac Output, High, Cardiac Output, Low
Pulse Contour Analysis and Tissue Oxymetry in Changing Vascular Tone
The purpose of this study is to compare changes of minimally invasive arterial pulse contour cardiac output with changes of intermittent and continuous thermodilution cardiac output by pulmonary artery catheter in hemodynamic…
- Conditions
- Cardiac Output, High, Cardiac Output, Low, Vasodilation, Vasoconstriction
- Trial name
- NCT00583687
- Testing
- Vigileo TM / Flotrac TM (Minimally invasive cardiac output system consisting of arterial line sensor and cardiac output monitor), Passive leg raising, Volume challenge / Change of vasoactive drugs or inotropics
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Coronary Artery Bypass Grafting, Mitral Valve Surgery
Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass
A study to evaluate levosimendan compared with placebo in reducing the composite event rate of all-cause death, perioperative MI, need for new dialysis, or use of mechanical assist (IABP, LVAD or ECMO) in subjects with reduced…
- Conditions
- Coronary Artery Bypass Grafting, Mitral Valve Surgery, Low Cardiac Output Syndrome
- Trial name
- LEVO-CTS (NCT02025621)
- Testing
- Levosimendan
- Where
- 60 sites in United States, Canada
- Volunteers
- 882 people
- Sponsor
- Tenax Therapeutics, Inc.
Dobutamine, Milrinone , Pediatrics , Low Cardiac Output
Dobutamine Versus Milrinone in Management of Critically Ill Low Cardiac Output Pediatric Patients at Cairo University Children's Hospital
The aim of the study is to detect wither dobutamine or milrinone have a privilege in the management of low cardiac output pediatric patients over the other.
- Trial name
- NCT05999487
- Testing
- Dobutamine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Hemodynamic Instability
Pulse Pressure Variation Helps to Predict Fluid Responsiveness in Patients Ventilated With Low Tidal Volumes
Objective: To determine the value of pulse pressure variation (ΔRESPPP) to predict fluid responsiveness in patients ventilated with low tidal volumes (VT), and to investigate whether a lower ΔRESPPP cut-off point should be used…
- Trial name
- NCT01569308
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Cardiac Output, Low
Cardiac Index Changes With Ephedrine, Phenylephrine, Ondansetron and Norepinephrine During Spinal Anesthesia
The purpose of the study is to evaluate the cardiac output changes after an intravenous bolus of ephedrine, phenylephrine, ondansetron or norepinephrine during a spinal anesthetic for a cesarean delivery.
- Trial name
- EPhON (NCT03421860)
- Testing
- cardiac output changes with "ephedrine", cardiac output changes with "phenylephrine", cardiac output changes with "ondansetron"
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Cardiac Output, Low, Cardiac Output, High
Echo FLOW Versus (Non-)Invasive Haemodynamics
Rationale: Diligent fluid management is instrumental to improve postoperative outcome, cost and quality of care. Objective: To determine the accuracy of brachial, femoral and carotid blood flow measurement with ultrasound…
- Trial name
- EFLOW (NCT04593797)
- Testing
- carotid blood flow measurement with ultrasound
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Cardiac Output, Low
Corticosteroids in Postoperative Critically Ill Neonates With Low Cardiac Output Syndrome With Congenital Heart Disease
Babies having heart surgery often have problems after surgery with their blood pressure and getting enough blood to their bodies.
- Trial name
- Corti (NCT00590018)
- Testing
- Hydrocortisone
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Baylor College of Medicine
Hemodynamics Instability, Anesthesia, General
Hemodynamics During Induction of General Anesthesia With High and Low Propofol Dose.
The study objective is to examine if a high propofol dose is non-inferior to a low dose in respect to hemodynamic stability in healthy patients during induction of general anesthesia with propofol and remifentanil.
- Conditions
- Hemodynamics Instability, Anesthesia, General, Anesthesia, Intravenous
- Trial name
- PH (NCT03861364)
- Testing
- Propofol
- Where
- Norway
- Volunteers
- 68 people
- Sponsor
- Helse Fonna
Low Cardiac Output
Comparison of Techniques for Assessing Cardiac Output and Preload in Critically Ill Pediatric Patients
Each year in the United States more than 30,000 children are admitted to intensive care units. The majority of these children have some degree of heart instability during their stay, yet there is currently no routine way to…
- Trial name
- NCT00167440
- Where
- United States
- Sponsor
- University of Rochester
Apnea of Prematurity, Preterm Birth
Hemodynamic Responses to Cardio-respiratory Events in Preterm Infants
Intermittent episodes of hypoxemia and/or bradycardia, also defined as cardio-respiratory events (CRE) are very frequent in preterm infants and may result in transient hypoxia and hypoperfusion of target organs, with possible…
- Conditions
- Apnea of Prematurity, Preterm Birth, Patent Ductus Arteriosus, Hypoxia, Brain
- Trial name
- NCT04184245
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Cardiac Output, Low, High Blood Pressure
Assessment of Volumetric Hemodynamic Parameters and Nutritional Status in Stable Renal Transplant Recipients
Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 …
- Trial name
- NCT02852941
- Testing
- CardioScreen 1000, Tanita 418- Bioelectrical impedance analysis
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Cardiac Output, Low
Spanish Randomized Clinical Trial to Compare Levosimendan Versus Placebo in Postoperative Cardiac Surgery (SPARTANS)
Low cardiac output Syndrome (LCOS) is a complication that appears in approximately 20% of cardiac surgeries with extracorporeal circulation.
- Trial name
- SPARTANS (NCT04179604)
- Testing
- Levosimendan
- Where
- 9 sites in Spain
- Volunteers
- 300 people
- Sponsor
- María de los Ángeles Tena Pajuelo
Congenital Heart Disease, Disorder of Fetus or Newborn
Preoperative Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass
Randomized controlled trial of the use of glucocorticoids to improve the clinical course of neonates post-cardiopulmonary bypass (CPB).
- Trial name
- NCT00934843
- Testing
- methylprednisolone (IVMP), methylprednisolone (two doses IVMP)
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Medical University of South Carolina
Low Cardiac Output Syndrome
Levosimendan Administration in Neonates With Transposition of the Great Arteries
Calcium sensitizer drugs such as Levosimendan may exert anti-ischemic effect in addition to positive inotropic and anti-stunning effects mediated by the opening of ATP-sensitive potassium (KATP) channels.
- Trial name
- NCT01120106
- Testing
- levosimendan
- Where
- Italy
- Volunteers
- 63 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Hypovolemia, Impaired Oxygen Delivery
Observational Study of Oxygen Delivery During a Fractional Fluid Expansion
Fluid expansion during cardiocirculatory insufficiency was helped by cardiac output monitoring. However, the goal of fluid expansion was to increase the oxygen delivery, which consider cardiac output, but also Haemoglobin which…
- Conditions
- Hypovolemia, Impaired Oxygen Delivery, Cardiac Output, Low
- Trial name
- OR (NCT01826253)
- Testing
- hydroxyethylstarch 130/0.4
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Caen
Cardiac Output, Low, Cardiac Output, High
Non-invasive Continuous Cardiac Output Monitoring in Preterm Infants Study
This is an observational study in newborn term and preterm infants. The study will validate if non-invasive continuous cardiac output monitoring is feasible in newborn infants, if normative values can be constructed and what is…
- Conditions
- Cardiac Output, Low, Cardiac Output, High, Blood Pressure
- Trial name
- NICCOM (NCT04064177)
- Testing
- NICAS cardiac output monitor
- Where
- United Kingdom
- Volunteers
- 148 people
- Sponsor
- Imperial College Healthcare NHS Trust
Burns
Cardiac Output Monitoring in Burn Patients
The purpose of this study is to describe the use of non-invasive cardiac output monitors (NICOM) in patients with burn injuries and to develop a protocol for NICOM in a burn unit.
- Trial name
- NCT02404597
- Testing
- NICOM (non-invasive cardiac output monitor)
- Where
- United States
- Sponsor
- Emory University