Clinical trials: Cardiac Output Measurement
Heart Diseases
The Precision of Pulmonary Artery Cardiac Output-measurements in Spontaneously Breathing Patients
The intention of this study is to determine whether the precision of the measure of cardiac output can be optimized by conducting the measurement while the participant is instructed to exhale slowly.
- Trial name
- TEMP2 (NCT01944254)
- Testing
- Cardiac output measurement at random to respiration, Cardiac output measurement synchronised at start of expiration, Cardiac output measurement timed to instructed exhalation
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Norwegian University of Science and Technology
Cardiac Output Measurement
Comparative Noninvasive Continuous Cardiac Output by the Clearsight With Invasive Monitoring by Pulsioflex in Abdominal Surgery
In high-risk patients, it is now recommended to guide the intraoperative volume replacement via the stroke volume. Today, the most commonly used technique for estimating the stroke volume is the arterial waveform analysis in the…
- Trial name
- CLEARSIGHT (NCT02717468)
- Testing
- Cardiac output and stroke ejection volume monitoring with arterial waveform analysis in the digital artery (ClearSight®), Cardiac output and stroke ejection volume monitoring with arterial waveform analysis in the radial artery (Pulsioflex®).
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Poitiers University Hospital
Hypotension During Cesarean Delivery, Spinal Anesthesia
Ninvasive Cardiac Output Measurements During Cesarean Delivery Under Spinal Anesthesia.
The purpose of the study is to learn more about how the heart works during cesarean delivery under spinal anesthesia (medicines given in the spine that numb parts of your body to block pain) in women.
- Trial name
- NCT01928797
- Testing
- Cardiac output monitor data
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Brigham and Women's Hospital
Cardiac Physiology, Cardiac Output
The Feasibility and Accuracy of Exhaled CO2 to Measure Cardiac Output in Ventilated Patients Without Tracheal Intubation
The purpose of this study is to test the accuracy of a new noninvasive way to measure how much blood our heart pumps per minute.
- Trial name
- NCT00783679
- Testing
- NICO device
- Where
- United States
- Sponsor
- Massachusetts General Hospital
AKI - Acute Kidney Injury, Cardiac Surgery
Urine Output Response to Fluid and Diuretic Therapy in Cardiac ICU Patients Monitored With FIZE kUO®
This prospective observational study evaluates the real-time urine output response to fluid therapy and diuretics in cardiothoracic intensive care unit (CTICU) patients monitored with the FIZE kUO® device.
- Conditions
- AKI - Acute Kidney Injury, Cardiac Surgery, Fluid Therapy, Hemodynamic Instability
- Trial name
- NCT07022314
- Testing
- FIZE kUO®
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- FIZE Medical ltd
Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension
Non-Invasive Measurement of Cardiac Output and Stroke Volume in PAH/CTEPH
Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are severe clinical conditions that, despite advances in therapeutics over the past 20 years, lead to serious morbidity and…
- Trial name
- NCT05618093
- Testing
- Non-invasive hemodynamic measurements
- Where
- United States
- Sponsor
- University of California, Los Angeles
Extracorporeal Membrane Oxygenation
The Consistency of Cardiac Output Measurements by Different Methods in VA-ECMO Patients
Objective： 1. To evaluate the consistency of cardiac output measured by different hemodynamic monitoring methods in patients with VA-ECMO 2.
- Trial name
- NCT04102072
- Testing
- Trendelenburg Maneuver, dobutamine stress test
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Zhongshan Hospital
Open Heart Surgery
CTICU Device Study CRUISE
The goal of this study evaluate three novel, Food and Drug Administration (FDA)-approved devices currently used to monitor blood pressure and the amount of blood that the heart pumps during each beat.
- Trial name
- CRUISE (NCT06828432)
- Testing
- CRUISE CTICU CareTaker Vitalstream Device, CRUISE CTICU CNAP Device, CRUISE CTICU Edwards Clearsight Device
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Hernando Gomez
Colon Carcinima
The Application of the ELFI-TECH Monitor for Perioperative Hemodynamic Measurements
The elfitor device is a small non invasive device that uses dynamic light scattering to measure skin bloodflow, blood velocity, coagulation and hemodynamic parameters.
- Trial name
- NCT02628431
- Testing
- Elfi tech monitor
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Leiden University Medical Center
Cardiac Output, Low, Surgery
Validation of Automated Cardiac Output Measurement
Automated software analysis now allows for quick estimation of cardiac output from the echocardiographic 5-chamber view. This study will validate the automated software method against pulmonary artery thermodilution and against…
- Trial name
- NCT03372863
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Sepsis
Non-invasive Measurement of CO in Patients With Uncomplicated Sepsis
Little is known about the optimal fluid therapy of patients with uncomplicated sepsis. Most recommendations are extrapolated from studies performed in patients with septic shock.
- Trial name
- NCT03728998
- Testing
- Passive leg raise (PLR), Clearsight non-invasive hemodynamic monitoring system
- Where
- Netherlands
- Volunteers
- 31 people
- Sponsor
- Frisius Medisch Centrum
Shock, Cardiogenic, Shock Hypovolemic
Clinical Validation of Algorithms for Mean Systemic Filling Pressure and Automated Cardiac Output
Prospective combined clinical validation of an algorithmic calculated mean systemic filling pressure (Pms-Nav) with the gold standard for Pms (Pms calculated from venous return curves during inspiratory hold procedures with…
- Conditions
- Shock, Cardiogenic, Shock Hypovolemic, Hypovolemia, Cardiac Failure
- Trial name
- PP3D (NCT04202432)
- Testing
- Mean systemic filling pressure
- Where
- Netherlands
- Volunteers
- 18 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Cardiac Output
Accurate Measurement of Cardiac Output Using the Ultrasound Dilution Technique
Accurate cardiac output determination is a commonly used and important index of myocardial performance. The thermodilution method using a pulmonary artery catheter is the most common approach to cardiac output determination…
- Trial name
- BCM (NCT00851422)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Transonic Systems Inc.
Neurological Outcome
Non-invasive Measurement of Regional Intracerebral Tissue Oxygenation in Elective Cardiac Surgeries
Patients after cardiac surgical operations often exhibit neuropsychological complications. In particular, the post-operative delirium is associated with a significantly increased morbidity and mortality.
- Trial name
- CSINVOS (NCT01412619)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- RWTH Aachen University
Coronary Bypass
Measurement of Pulse Pressure Variation and Cardiac Output by a New Application for Android™ (Captesia™)
This study test the agreement and accuracy of Pulse Pressure Variation (PPV) and Cardiac Output (CO) obtained by the Android application Capstesia™ against the gold standard : PPV and CO calculated by thermodilution.
- Trial name
- NCT02692222
- Testing
- Calculation of PPV and CO with two methods
- Where
- Belgium
- Volunteers
- 57 people
- Sponsor
- Erasme University Hospital
Cardiac Output Measurement
Comparative Noninvasive Continuous Cardiac Output by the Clearsight® With Invasive Monitoring by PICCO® in Abdominal Major Surgery
In high-risk patients, it is now recommended to guide the intraoperative volume replacement via the stroke volume. Today, the most commonly used technique for estimating the stroke volume is the transpulmonary thermodilution and…
- Trial name
- CLEARPICCO (NCT02941952)
- Testing
- Cardiac output and stroke ejection volume monitoring with both ClearSight® and PICCO® in major abdominal surgery.
- Where
- France
- Sponsor
- Poitiers University Hospital
Cardiac Output
Measurement of Cardiac Output and Blood Volumes
Cardiac Output (amount of blood pumped by the heart in one minute) will be measured using the new COstatus(R) system and these values will be compared with cardiac output values measured by other methods such as thermodilution.
- Trial name
- WSU (NCT00851474)
- Where
- United States
- Sponsor
- Transonic Systems Inc.
Perfusion Pressures, Central Venous Pressure
Sternal Wall Pressure in the Cath Lab
This protocol is a prospective interventional pilot study at the Children's Hospital of Philadelphia to determine whether or not two increments of sternal pressure known to occur during "leaning" in CPR affects hemodynamic…
- Conditions
- Perfusion Pressures, Central Venous Pressure, Cardiac Output, CPR
- Trial name
- NCT01117883
- Testing
- Application of two different sternal weights
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Philadelphia
Pulmonary Hypertension
Noninvasive Cardiac Output Measurements in Patients With Pulmonary Hypertension Undergoing Exercise Testing
Subjects in this study have been diagnosed with pulmonary hypertension and their doctors have referred them for an exercise test as part of their normal, routine care.
- Trial name
- NCT01275703
- Where
- United States
- Sponsor
- University of Chicago
Shock, Hypotension and Shock
ClearSight Validation in Pediatrics
Specific aim 1: The specific aim of this study is to compare cardiac output measurements as well as cardiac index, and stroke volume obtained via thermodilution during a cardiac catheterization with data obtained by the…
- Trial name
- NCT03701646
- Testing
- Measurement by Clearsight device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Nemours Children's Clinic