Clinical trials: Cardiac Output Measurement
Blood Pressure Measurement
Agreement of the Nexfin™ Monitor With Non-invasive Blood Pressure Measurement
Currently, BP is measured using an inflatable cuff wrapped around the patient's upper arm. This can be set to inflate every minute, but measurement may fail due to patient movement or shivering.
- Trial name
- Nexfin Pilot (NCT02447471)
- Testing
- Nexfin
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Congestive Heart Failure
Non-Invasive Cardiac Output Measurement for CRT Optimization
This proposal aims to evaluate the added clinical and echocardiographic benefit of using the non-invasive impedance-based cardiac output measurement system (NICaS) for optimizing atrio-ventricular and inter-ventricular delays in…
- Trial name
- NICaS-CRT (NCT02126241)
- Testing
- NICaS guided CRT optimization
- Where
- Israel
- Volunteers
- 42 people
- Sponsor
- Sheba Medical Center
Critical Illness, Pediatrics
Comparing Cardiac Output Measurements in Critically Ill Children Using USCOM and Transthoracic ECHO
The purpose of this study is to compare the accuracy and precision of two non-invasive methods of measuring cardiac output in critically ill children (<18 yrs).
- Trial name
- NCT01460329
- Testing
- Ultrasonic Cardiac Output Monitor (USCOM).
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of North Carolina, Chapel Hill
Fluid Responsiveness, Cardiac Output
Echocardiography in Kids Intensive Care Decision Support
A study to determine if echocardiographically derived parameters, plethysmographic variability index and pulse pressure variation predict fluid responsiveness in children on PICU.
- Trial name
- ECHOKIDS (NCT01821742)
- Testing
- Ultrasound cardiac output measurement
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Imperial College London
Congestive Heart Failure
Assess Measurements of Wireless Cardiac Output Device
Heart failure is a common cardiovascular problem which is increasing in both prevalence and incidence and associated with substantial morbidity and mortality.
- Trial name
- Remote-CO-1 (NCT02252757)
- Testing
- CoVa
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Aventyn, Inc.
Post Cardiac Surgery Patients
Measurement of Cardiac Output and Blood Volumes Using Transonic Ultrasound Dilution Technology
Measurement of the amount of blood pumped by the heart (cardiac output) and blood volumes in sick patients is important for doctors to better treat these patients.
- Trial name
- NCT00756119
- Where
- Russia
- Volunteers
- 26 people
- Sponsor
- Transonic Systems Inc.
Acute Kidney Injury
Continuous Central Venous Oxygen Saturation Measurement as a Tool to Predict Hemodynamic Instability Related to Renal Replacement Therapy in Critically Ill Patients
Acute kidney injury (AKI) is common in intensive care unit (ICU) and inducing a high morbidity and mortality. In severe forms of AKI (more than 25% of AKI patients admitted to the ICU), renal replacement therapy (RRT) is often…
- Trial name
- SoVHIRR (NCT05897840)
- Testing
- Fiber-optic probe CeVOX
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Cardiac Output, Critically Ill
Arterial Tone Influence on Cardiac Output Measured by PRAM
This study evaluates the role of arterial tone in the accuracy of cardiac output (CO) measurement by Pressure Recording Analytical Method (PRAM).
- Trial name
- NCT03900546
- Testing
- MostCare
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- Università Politecnica delle Marche
Pulmonary Hypertension
Noninvasive Cardiac Output Measurements in Patients With Pulmonary Hypertension Undergoing Right Heart Catheterization With Acute Vasodilator Testing
Subjects in this study have been diagnosed with pulmonary hypertension (PH) and their doctors have referred them for a right heart catheterization (RHC).
- Trial name
- NCT01275690
- Sponsor
- University of Chicago
Cardiac Output Measurement
Discontinuous Echocardiographic Subcostal Cardiac Output Measurement
Cardiac output (CO) monitoring is recommended for the most serious and multiple-failure patients in critical care and allows the diagnosis of acute circulatory failure as well as its etiology and also allows the monitoring of…
- Trial name
- RIGHT WAY (NCT07177391)
- Testing
- Discontinuous subcostal echocardiographic cardiac output assessment
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Rouen
Heart Diseases
Study on the Repeatability of Cardiac Output Measurements Dependence of Temperature of Injectate
This study tests the reliability of thermodilution cardiac output measurements with pulmonary artery catheters in immediate connection with heart surgery.
- Trial name
- NCT00464750
- Testing
- Pulmonary artery catheter
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Norwegian University of Science and Technology
Cardiopulmonary Exercise Test, Hypertrophic Cardiomyopathy
Exercise Oxygen Kinetic and Cardiac Output in Hypertrophic Cardiomyopathy
Fatigue and dyspnea that reduce exercise performance are common symptoms in patients with hypertrophic cardiomyopathy. Since the cause of this functional limitation has not yet been described, this study aims to evaluate the…
- Conditions
- Cardiopulmonary Exercise Test, Hypertrophic Cardiomyopathy, Cardiac Output Measurement
- Trial name
- NCT05754489
- Where
- 3 sites in Italy
- Volunteers
- 90 people
- Sponsor
- Centro Cardiologico Monzino
Congenital Heart Diseases, Hemodynamic
Non-Invasive Shunt Quantification in Interatrial Communication
Shunt quantification in atrial septal defect (ASD) is estimated by Echocardiography-Doppler, with the pulmonary-to-systemic blood flow ratio: Qp/Qs.
- Conditions
- Congenital Heart Diseases, Hemodynamic, Cardiac Output
- Trial name
- NISQIC (NCT03437148)
- Testing
- Innocor®, Physioflow®
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Clermont-Ferrand
Cardiovascular Diagnostic Techniques
Cardiac Output Measurement With NICCOMO and PiCCO Devices at Different PEEP Levels
Thermodilution cardiac output measurement is a reliable method, but it is an invasive one. PiCCO device requires cannulation of central vein and peripheral artery. Impedance method requires only attachment of special electrodes.
- Trial name
- NCT02572739
- Testing
- PICCO, NICCOMO
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Gdansk
Hemodynamic Instability
Effect of Extended Infusion Lines on Pulse Contour-based Measurements
Hemodynamic monitoring of the critically-ill patients is increasingly performed using an arterial pulse contour-based cardiac output device such as the proAQT system.
- Trial name
- NCT03599440
- Testing
- Pressure line extensions
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Cardiac Output Measurement
MostCare Versus Echo-Doppler for Cardiac Output Measurement
Recently, an uncalibrated minimally invasive Pulse-code Modulator (PCM) has been developed: the MostCare system. This monitoring system is powered by Pressure Recording Analytical Method (PRAM), which is based on the mathematical…
- Trial name
- PRAM (NCT01678950)
- Where
- 14 sites in France, Italy and 2 more
- Volunteers
- 400 people
- Sponsor
- Azienda Ospedaliera Universitaria Senese
Heart Failure, Hypertension, Pulmonary
Measurement of Endothelial Function and Cardiac Output: New Methods
The main purpose of this study is to analyse test-retest-reliability of functional quantification of endothelial dysfunction through puls-amplitude-tonometry in patients with heart failure with preserved/reduced ejection…
- Conditions
- Heart Failure, Hypertension, Pulmonary, Hypertension, Diabetic Nephropathies
- Trial name
- NCT02299960
- Testing
- Endo-PAT, NICOM
- Where
- Germany
- Volunteers
- 101 people
- Sponsor
- Charite University, Berlin, Germany
Congenital Heart Disease
Noninvasive Measurement of CO Using Impedance Cardiography in Patients With CHD
This study will test the capability of a non-invasive instrument (the PhysioFlow impedance cardiography instrument) to measure cardiac output in patients with congenital heart disease (CHD).
- Trial name
- NCT02326649
- Testing
- Physioflow
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of California, San Diego
Cardiac Output, LIDCO Rapid, Septic Shock
Validation of Uncalibrated Cardiac Output Measurement With LiDCOrapid in the Resuscitation of Critically Ill Patients With Septic Shock: A Prospective Cross-sectional Study.
Transthoracic echocardiography (TTE) has been used as a reference technique for CO measurement and its accuracy has been adequate for many clinical uses. TTE is painless, safe and non-invasive.
- Trial name
- NCT04705493
- Testing
- fluid resuscitation with crystalloid
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Hemodynamically Stable, Critical Illness
Comparing USCOM and Echocardiographic Hemodynamic Measurements in Children (CUE Study)
The primary objective of this study is to evaluate the agreement between hemodynamic measurements obtained using the Ultrasound Cardiac Output Monitor (USCOM®; USCOM Ltd., Sydney, Australia), and reference standards as determined…
- Trial name
- NCT02083172
- Testing
- Ultrasound Cardiac Output Monitor and 2 D-Echo
- Where
- Canada
- Volunteers
- 78 people
- Sponsor
- McMaster University