Clinical trials: Cardiac Patients
Coronary Artery Disease, Percutaneous Coronary Intervention
Different Doses of Colchicine on hsCRP
Colchicine reduced atherothrombotic cardiovascular events in the COLCOT and LoDoCo2 studies. US Food and Drug Administration approved colchicine as the first anti-inflammatory drug for cardiovascular diseases on June, 2023.
- Trial name
- NCT06078904
- Testing
- Colchicine 0.5 MG, Colchicine 0.375 MG, Colchicine 0.25 MG
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Heart Failure, Diastolic, Multicenter Study
Diagnosis and OutcoMes evaluAtIoN of Multicenter Patients With HFpEF Using Multimodality Imaging
The incidence of Heart failure with preserved ejection fraction (HFpEF) in Heart failure patients increases rapidly. However, the current clinical awareness is insufficient, and the cardiac structural and functional injury are…
- Trial name
- NCT04602338
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Supraventricular Tachycardia (SVtach)
Efficacy of Adenosine as Compared to Verapamil in Paroxysmal Supraventricular Tachycardia (pSVT) Patients
Supraventricular tachycardia (SVT) is a term widely used to describe tachycardial dysrhythmias, paroxysmal SVT (PSVT) is a narrow term including only AV nodal re-entrant tachycardia (AVNRT) and atrioventricular re-entrant…
- Trial name
- NCT06717685
- Testing
- Adenosine, Verapamil Injection
- Where
- Pakistan
- Volunteers
- 210 people
- Sponsor
- Rashid Latif Medical College
Ventricular Tachycardia (VT)
Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)
Sphere-9 VT EFS is a prospective, multi-center, non-randomized, unblinded feasibility study. Adult subjects with recurrent, sustained, scar-related monomorphic ventricular tachycardia will be enrolled and treated with the…
- Trial name
- NCT06703489
- Testing
- Sphere-9 Catheter with the Affera Mapping and Ablation System
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Central Venous Catheterization
Comparison of the Proximal Approach and Distal Approach of Axillary Vein Catheterization Under Ultrasound Guidance
Ultrasound-guided axillary vein catheterization can be performed via the proximal or distal approach of the axillary vein. The aim of our study is to compare the first puncture success rate and safety between the two approaches…
- Trial name
- NCT03395691
- Testing
- The distal approach, The proximal approach
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Shanghai Zhongshan Hospital
Myocardial Infarction, No-Reflow Phenomenon
Ticagrelor and Clopidogrel on Reperfusion in Patients With AMI
The patients with acute myocardial infarction (AMI) present high mortality and morbidity rate,even treated with stenting in the blocked heart vessels. The appearance of no-reflow is common after re-opening of the blocked vessel.
- Trial name
- NCT02233790
- Testing
- Ticagrelor, Clopidogrel
- Where
- China
- Volunteers
- 600 people
- Sponsor
- First Hospital of China Medical University
Chronic Obstructive Lung Disease (COLD), Heart Failure
Reforça't: A Community, Social, and Healthcare Program for Patients With Cardiorespiratory Conditions Upon Hospital Discharge
The goal of this randomized clinical trial is to determine whether an interdisciplinary, community-based intervention can reduce 30-day hospital readmissions and improve functional outcomes in patients aged 65 or older with…
- Trial name
- R't (NCT06897410)
- Testing
- Interdisciplinary Program for Post-Hospitalization / Hospital at home Management and Long-Term Outcomes in Older Adults with Chronic Cardiorespiratory Condition
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Corporació de Salut del Maresme i la Selva
Anxiety
Effects of Stress Ball Use on Heart Rate Variability, Anxiety, and Pain During Awake Hand Surgery: A Randomized Controlled Trial
Preoperative anxiety begins from the decision-making of surgery to entering the operating room and may intensify as the surgery date approaches.
- Trial name
- NCT06742814
- Testing
- stress ball
- Where
- 2 sites in Taiwan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Heart Failure, Heart Failure With Preserved Ejection Fraction
Balance, Aerobic Capacity, Mobility and Strength in Patients Hospitalized for Heart Failure (BAMS-HF) Program
This is a pilot randomized trial of the BAMS-HF (Balance, Aerobic capacity, Mobility and Strength in patients hospitalized for Heart Failure) Program versus usual care.
- Conditions
- Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure, Systolic, Heart Failure, Diastolic
- Trial name
- BAMS-HF (NCT04281849)
- Testing
- BAMS-HF Program
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Eastern Colorado Health Care System
STEMI
Intensive Statin Treatment for STEMI Patients Undergoing Primary PCI
This is a retrospective, randomized, parallel, open-labeled, controlled study to find out whether STEMI patients undergoing emergency PCI can benefit from intensive atorvastatin treatment compared with routine treatment.
- Trial name
- NCT01033058
- Testing
- atorvastatin
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Beijing Chao Yang Hospital
CaIMR, Prognosis
The Usefulness of CaIMR in Patients With STEMI
The coronary artery system is composed of three different types of blood vessels, namely epicardial arteries, arterioles and capillaries.
- Conditions
- CaIMR, Prognosis, ST-segment Elevation Myocardial Infarction
- Trial name
- NCT04984915
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Zhongnan Hospital
Hypercholesterolemia
A 12 Week Study of MK0653A in Patients Who Have Been Hospitalized for a Possible Heart Problem (0653A-808)
The purpose of this study is to investigate the effect of an investigational cholesterol-lowering drug in patients who are currently taking an approved medication for hypercholesterolemia (high cholesterol levels) and have been…
- Trial name
- NCT00132717
- Testing
- MK0653A (ezetimibe [+] simvastatin), Comparator: atorvastatin, Comparator: fluvastatin
- Volunteers
- 450 people
- Sponsor
- Organon and Co
Intubation, Cardiovascular Surgical Procedure
Reducing Reintubation Risk in High-Risk Cardiac Surgery Patients With High-Flow Nasal Cannula
The iCAN trial is a pragmatic randomized controlled trial that aims to test the hypothesis that HFNC versus usual care oxygenation strategies applied immediately after initial extubation after cardiac surgery decreases the…
- Trial name
- NCT04782817
- Testing
- Recommendation for high flow nasal cannula oxygen therapy order set, Provider choice usual care order set
- Where
- United States
- Volunteers
- 3,568 people
- Sponsor
- Vanderbilt University Medical Center
Atrial Fibrillation, Obstructive Sleep Apnea
The Efficacy of PAP Therapy on Reducing AF Recurrence in Patients With Morbidity of OSA
This study aims to test the effectiveness of positive airway pressure therapy on reducing clinical failure after rhythm control treatment and restoring with regular heart beat in atrial fibrillation patients with obstructive…
- Trial name
- AFOSA (NCT04519489)
- Testing
- PAP therapy with telemonitoring, AF standard management and OSA general care
- Where
- 2 sites in China
- Volunteers
- 129 people
- Sponsor
- Philips (China) Investment CO., LTD
Tricuspid Regurgitation, Tricuspid Insufficiency
Transcatheter Repair of Tricuspid Regurgitation With Edwards Cardioband TR System Post Market Study (TriBAND)
The purpose of the study is to assess the safety and the effectiveness of the Cardioband Tricuspid Reconstruction System.
- Trial name
- TriBAND (NCT03779490)
- Testing
- Transcatheter Tricuspid Valve Repair
- Where
- 14 sites in Germany, Spain and 1 more
- Volunteers
- 150 people
- Sponsor
- Edwards Lifesciences
Heart Failure
Effects of CCM-therapy in Patients With Heart Failure
The effects of Cardiac Contractility Modulation (CCM) treatment are observed in patients with heart failure.
- Trial name
- CCM-HF (NCT02895048)
- Where
- Germany
- Volunteers
- 184 people
- Sponsor
- Stiftung Institut fuer Herzinfarktforschung
Atrial Fibrillation (AF)
Redo-Pulmonary Vein Isolation With Versus Without Posterior Wall Ablation - The REDO-PIFPAF-PFA Study
The study will compare two ablation strategies in patients with paroxysmal or persistent atrial fibrillation undergoing repeat ablation using pulsed-field ablation: redo pulmonary vein isolation only versus redo pulmonary vein…
- Trial name
- NCT07745543
- Testing
- Pulmonary vein isolation with posterior wall ablation, Pulmonary vein isolation without posterior wall ablation
- Where
- 5 sites in Switzerland
- Volunteers
- 270 people
- Sponsor
- University Hospital, Basel, Switzerland
Heart Failure
Symptom Burden and Health Related Quality of Life of Cancer Patients With Concurrent Heart Failure
To describe and compare the symptom burden in cancer patients with concurrent diagnosis of heart failure (HFrEF compared to HFpEF).
- Trial name
- NCT06656715
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- M.D. Anderson Cancer Center
Heart Failure
Mobile Technology-Based System for Patient Engagement and Physician-Directed Remote Management of Heart Failure
This pilot study is to assess the feasibility, preliminary utility and acceptance of a digital technology-based system for heart failure management.
- Trial name
- NCT05647317
- Testing
- A combination of a provider-facing desktop and mobile application with a patient-facing mobile application
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Patient Comfort, Anxiety
Family Support Weaning from Mechanical Ventilation in Cardiovascular Surgery
Mechanical ventilation support is used to ensure airway clarity in patients after surgery.If patients are not informed about mechanical ventilation treatment in the pre -operation period, panic, anxiety and comfort may be…
- Conditions
- Patient Comfort, Anxiety, Patient Satisfaction
- Trial name
- NCT05820789
- Testing
- Family support
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kastamonu University
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