Clinical trials: Cardiac-Related Conditions
Myocardial Infarction (MI)
Efficacy and Safety Study of Proposed Biosimilar Product Reveliza vs Actilise in Patients With ST-segment Elevation Myocardial Infarction
Thi is is a multi-center, randomized, single-blind, parallel group clinical trial to evaluate the efficacy and safety of the intravenious thrombolysis with Revelise® (GENERIUM, Russia) in comparosin with the Actilyse® (Boehringer…
- Trial name
- NCT07146360
- Testing
- Revelise (GENERIUM, Russia), Actilyse® (Boehringer Ingelheim Pharma GmbH and Co.KG, Germany)
- Where
- 22 sites in Russia
- Volunteers
- 180 people
- Sponsor
- AO GENERIUM
Atrial Fibrillation
Age Related D-dimer Evaluation for the Exclusion of a Left Atrium Thrombus in Patients With Atrial Fibrillation (ADDIT-AF)
Patients with atrial fibrillation are at increased risk of thrombus formation in the left heart, especially in the auricula and the atrium.
- Trial name
- NCT02802488
- Testing
- Blood sampling
- Where
- Belgium
- Volunteers
- 142 people
- Sponsor
- Brugmann University Hospital
Cardiac Arrhythmias
Evaluation of an Innovative Smart T-shirt Capable to Monitor ECG Signal and Related Parameters Through the Comparison With a Holter ECG and a Smartwatch
Evaluation of an innovative smart t-shirt capable to monitor ECG signal and related parameters through the comparison with a Holter ECG and a smartwatch
- Trial name
- Youcare (NCT05771142)
- Testing
- Smart t-shirt, ECG Holter, Smartwatch
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Bologna
Myocardial Infarction, Acute Coronary Syndrome
Clinical and Atherosclerotic Characteristics of Patients With ACS Associated With Cocaine Use
Cocaine use has increased in our country in recent decades. It is associated with cardiovascular events and early atherosclerotic disease. Acute coronary syndrome (ACS) is one of its most frequent and serious manifestations.
- Conditions
- Myocardial Infarction, Acute Coronary Syndrome, Cocaine Use, Cocaine Abuse
- Trial name
- NCT06177860
- Where
- Argentina
- Volunteers
- 400 people
- Sponsor
- Hospital El Cruce
Out-Of-Hospital Cardiac Arrest, Trauma
AI to Improve Data From Danish Cardiac Arrest Registry
Out-of-hospital cardiac arrest is a leading cause of death worldwide and patient outcome vary substantially throughout regions suggesting further evaluation and potential for improvement.When focussing on subgroups of OHCA, data…
- Conditions
- Out-Of-Hospital Cardiac Arrest, Trauma, Drug Overdose, Electrocution
- Trial name
- NCT05308303
- Where
- Denmark
- Volunteers
- 31,200 people
- Sponsor
- Prehospital Center, Region Zealand
SCAD, Addison Disease
Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity
This case control study aims to determine whether spontaneous coronary artery dissection (SCAD) is associated with autoimmune diseases and to update the incidence of SCAD in a population-based cohort.
- Conditions
- SCAD, Addison Disease, Ankylosing Spondylitis, Antiphospholipid Antibody Syndrome
- Trial name
- NCT03941184
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Mayo Clinic
Cardiac Surgery, Organ Protection
Age Related Chromatin Remodelling as a Therapeutic Target for Organ Protection in Cardiac Surgery
People who have multiple long-term conditions (MLTC) like kidney disease or lung disease are at higher risk of developing organ damage and poor quality of life following heart surgery.
- Conditions
- Cardiac Surgery, Organ Protection, Ageing
- Trial name
- EPI-CARD (NCT07389785)
- Testing
- other
- Where
- United Kingdom
- Volunteers
- 3,055 people
- Sponsor
- University of Leicester
Oncology, Cardiac Toxicity
Exercise Response After Revalidation in Cancer Patients
This study regarding oncological patients for rehabilitation after specific cancer therapy involves three aims: (1) to evaluate the predictive value of myocardial work parameters on the improvement of exercise performance after…
- Trial name
- NCT04461392
- Testing
- Cardiorespiratory exercise test
- Where
- Belgium
- Volunteers
- 191 people
- Sponsor
- Universitair Ziekenhuis Brussel
Carbon Monoxide Poisoning
The Efficacy of L-Carnitine in the Management of Acute Carbon Monoxide Poisoning
Carbon monoxide (CO) poisoning results in high morbidity and mortality worldwide. CO is described as a "silent killer" because CO is colorless, odorless, and tasteless but highly toxic.
- Trial name
- NCT05647707
- Testing
- L-Carnitine
- Volunteers
- 72 people
- Sponsor
- Alexandria University
Left Ventricular Function Systolic Dysfunction, Cardiotoxicity
Usefulness of Myocardial Deformation Imaging for Trastuzumab-induced Cardiotoxicity
Trastuzumab prolongs survival in patients with human epidermal growth factor receptor type 2-positive breast cancer. Sequential left ventricular (LV) ejection fraction (EF) assessment has been mandated to detect myocardial…
- Trial name
- NCT01665300
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Seoul National University Hospital
Epilepsy, Cardiac Disease
Epileptic Potentials During Cardiac Surgery and Association With Postoperative Neurological Outcome
Primarily, the investigators want to test the hypothesis that it is possible to detect epileptiform EEG during cardiac surgery under general anesthesia.
- Conditions
- Epilepsy, Cardiac Disease, Peroperative Complications, Anesthesia; Adverse Effect
- Trial name
- EPOCAS (NCT02976584)
- Where
- Switzerland
- Volunteers
- 1,067 people
- Sponsor
- Heiko Kaiser
Coronary Disease, Myocardial Infarction
Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures, Third Wave
The CLIMATE-III Observational Study examines to what extent chronically ill patients experience adverse health effects because of heat and whether the patients' specific health behavior, somatosensory amplification, risk and…
- Conditions
- Coronary Disease, Myocardial Infarction, Heart Failure, Arrhythmias, Cardiac
- Trial name
- CLIMATE-III (NCT06890208)
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 176 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Myocardial Infarction
Quality and Safety of Initial Management for ST-segment Elevation Myocardial Infarction
This is a multicenter multidisciplinary study designed to investigate patient, provider, and system-related factors that are associated with the quality and safety of initial management for suspected ST-segment elevation…
- Trial name
- STEMI-Qual (NCT02788344)
- Testing
- Daily practice care for patients with suspected of STEMI
- Where
- France
- Volunteers
- 6,920 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Obesity
Research Study to Investigate How Well Semaglutide Works in People Living With Heart Failure and Obesity
This study will look at how the participants daily life is affected by their heart failure. The study will also look at the change in participants body weight from the start to the end of the study.
- Trial name
- STEP-HFpEF (NCT04788511)
- Testing
- Semaglutide
- Where
- 146 sites in United States, Argentina and 11 more
- Volunteers
- 529 people
- Sponsor
- Novo Nordisk A/S
Coronary Artery Disease
The Relationship Between Cognitive Status and Exercise Capacity, Fatigue Perception in Coronary Artery Patients
The study aimed to examine the relationship between cognitive status, exercise capacity, and fatigue perception in coronary artery disease patients.
- Trial name
- NCT06246201
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Cancer
Cardiac Aggressive Risk Mitigation in Thoracic Radiotherapy (CARMA) Trial
The purpose of this study is to examine adherence to cardio-oncology consultation.
- Trial name
- CARMA (NCT05403736)
- Testing
- Cardiac Aggressive Risk MitigAtion Plan
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Atrial Fibrillation
The Effect of Nurse Practitioner Led-Care on Quality of Life in Patients With Atrial Fibrillation
Atrial fibrillation (AF) is the most common heart rhythm disease characterized by an irregular heart rhythm of the top part (atria) of the heart.
- Trial name
- NCT02745236
- Testing
- Nurse Practitioner Led-Care, Cardiologist Led-Care
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Alberta
Accidental Hypothermia, Hyperkalemia
Measurement of Serum Potassium Rate During Accidental Hypothermia.
Serum Potassium Rate (PR) is a key indicator for medical management of patients with accidental hypothermia particularly for hypothermia related cardiac arrest (CA).
- Conditions
- Accidental Hypothermia, Hyperkalemia, Cardiac Arrest
- Trial name
- Kai+ (NCT03096561)
- Testing
- blood draw from three different vessels
- Where
- 2 sites in Switzerland
- Volunteers
- 12 people
- Sponsor
- University Hospital, Grenoble
Atrial Fibrillation, Stroke
Transient Electrocardiogram Assessment in Stroke Evaluation
In stroke survivors, atrial fibrillation is typically detected with short-term electrocardiogram (ECG) monitoring in the stroke unit.
- Trial name
- TEASE (NCT03301662)
- Testing
- chest and thumb- ECG
- Volunteers
- 100 people
- Sponsor
- Region Gävleborg
Chest Pain
A Study of the Use of High-dose Proton Pump Inhibitor for the Treatment of Gastro-oesophageal Reflux Related Non-cardiac Chest Pain - a Randomized Double-blind Placebo-controlled Study
Non-cardiac chest pain accounts for 2-5% of all emergency presentations. In the United States, it has been estimated approximately that US$8 billion was spent annually for the initial care of patients suspected to have an acute…
- Trial name
- NCT00517270
- Testing
- Rabeprazole 20mg twice daily
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Hospital Authority, Hong Kong