Clinical trials: Cardio-metabolic Health
Prediabetic State
Evaluation of a Community Health Program for the Prevention of Type 2 Diabetes and Other Cardio-metabolic Risk Factors in Adults: Districts of Barranquilla and Bogota, Colombia - January 2017 - December 2019
The main aim of this study is to evaluate the feasibility and effectiveness of a program for modifying lifestyles for diabetes prevention type 2 and control cardio-metabolic risk factors in adults with different categories of…
- Trial name
- PREDICOL (NCT03049839)
- Testing
- Intervention_ S, Intervention_ I, Intervention_ C
- Where
- 2 sites in Colombia
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Universidad del Norte
Gut Microbiome, Cholesterol, LDL
Corn and Heart Health Study
The purpose of this study is to investigate the effects of 3 different corn flours: (1) whole grain corn flour, (2) 50% refined corn flour + 50% corn bran derived from whole corn meal, and (3) refined corn flour, on…
- Conditions
- Gut Microbiome, Cholesterol, LDL, Cholesterol, HDL
- Trial name
- CHS (NCT03967990)
- Testing
- Refined cornmeal flour, 50/50 refined cornmeal-bran mix, Whole grain cornmeal flour
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Gestational Diabetes Mellitus
Improving Cardio-metabolic and Mental Health in Women With Gestational Diabetes Mellitus and Their Offspring
MySweetHeart Trial is a randomized controlled trial to test the effect of a multidimensional interdisciplinary lifestyle and psychosocial intervention to improve the cardio-metabolic and mental health of women with GDM and their…
- Trial name
- MySweetHeart (NCT02890693)
- Testing
- interdisciplinary lifestyle and psychosocial intervention
- Where
- Switzerland
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Cholesterol, Triglycerides
AlmegaPL CV Health Open Label Study
The aim of this study is to assess the effectiveness of Almega PL, a Nannochloropsis algae-derived extract rich in eicosapentaenoic acid (EPA), on improving blood markers associated with heart health of iwi customers.
- Conditions
- Cholesterol, Triglycerides, Omega-3, Eicosapentaenoic Acid
- Trial name
- NCT05267301
- Testing
- AlmegaPL (FDA NDIN # 826)
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Qualitas Health
Diet Pattern Analysis, Environmental Impact
Dairy Product Consumption and Impact on Nutritional Adequacy, Environment and Diet Cost
This is a secondary analysis of dietary, demographic and health parameter data collected in the 2008/09-2011/12 National Diet and Nutrition Survey (NDNS), UK to determine the roles of dairy products in sustainable diets by…
- Conditions
- Diet Pattern Analysis, Environmental Impact, Nutrient Intakes, Cardio-metabolic Health
- Trial name
- NCT03407248
- Where
- United Kingdom
- Volunteers
- 1,655 people, healthy volunteers welcome
- Sponsor
- University of Reading
Type2 Diabetes Mellitus, Cardiovascular Diseases
Mil Familias Cohort Establishment: a Study to Understand Determinants of Diabetes and Its Complications Among US Latinos
The Mil Familias Cohort Establishment involves enrolling 1000 Latino families with at least one member in the family having type 2 diabetes, including children and youth, and measuring the 5 determinants of human health…
- Trial name
- NCT03830840
- Where
- United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Sansum Diabetes Research Institute
Evaluations, Diagnostic Self, Treatment Adherence
Impact of Vitamin D Supplementation on Cardiometabolic Status and Androgen Profile in Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a heterogeneous disorder of reproductive, endocrine and metabolic functions. Vitamin D has an influence on metabolic and reproductive functions.
- Trial name
- NCT04117750
- Testing
- cholecalciferol (vit D3)
- Where
- Egypt
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Insomnia, Cardiorespiratory Fitness
Insomnia´s Impact on DNA Stability, Cardio-metabolic Health and Lifestyle Behaviors
Insomnia is a highly prevalent sleep disorder worldwide, with an increasing incidence in athletes, older adults, university students, and individuals with metabolic syndrome.
- Conditions
- Insomnia, Cardiorespiratory Fitness, Metabolic Disease
- Trial name
- INSIGHTS (NCT06869486)
- Testing
- Exercise, Bioelectrical Impedance, Micronucleus Assay
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Healthy Diet
The Effects of Western Diet Patterns on Plasma Inflammatory and Cardio Metabolic Health Signatures in Middle-aged Adults
The Western diet pattern or standard American diet is a modern dietary pattern that is characterized by high intakes of meat, pre-packaged foods, fried foods, high-fat dairy products, eggs, refined grains etc.
- Trial name
- NCT04275843
- Testing
- Traditional Diet, Modern Diet
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Duke University
Cardiovascular Disease
The Impact of Almond Nut Consumption on Markers of CVD & Metabolic Health
The purpose of this study is to investigate the cardio-metabolic health effects of consuming almond nuts in place of habitual (usual) snack products in adults at moderate risk of developing cardiovascular disease
- Trial name
- Almonds (NCT02907684)
- Testing
- Almonds, Muffins/Crackers
- Where
- United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- King's College London
Sleep, Body Composition
Impact of Protein Quantity Within the USDA Healthy Style Eating Pattern on Sleep
This evaluates the affect of protein quantity on indices of sleep. Half the participants will be prescribed protein in the amount consistent with the USDA healthy style eating pattern, while the other half will be prescribed a…
- Trial name
- NCT03174769
- Testing
- Normal protein, High protien
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Purdue University
Cardio Vascular Disease, Obesity & Overweight
Support Your Heart, Phase 1
This is a pilot feasibility study designed to establish the feasibility and acceptability of the "Support Your Heart" (SYH) study's phone-based protocols regarding AHA's LE8, social isolation, loneliness, and stress.
- Conditions
- Cardio Vascular Disease, Obesity & Overweight, Physical Activity, Sleep
- Trial name
- SYH (NCT07623733)
- Testing
- Support Your Heart
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- George Washington University
Obesity
The Irisin and Metabolic Exercise Training Study
It has been established that greater amounts of vigorous intensity physical activity lead to improved health outcomes. Interestingly, the response of biologically active substances, called myokines, differs according to exercise…
- Trial name
- iMET (NCT03514238)
- Testing
- High Intensity Interval Aerobic Exercise (HIIT), Continuous Moderate Aerobic Exercise (MOD), Control Sitting Condition (C)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of New Brunswick
Alzheimer Disease (AD), Cardio Vascular Disease
Arlington Longitudinal Optimal Healthy Aging Study (ALOHA)
The Arlington Longitudinal Optimal Healthy Aging (ALOHA) Study is a community-based research project led by the Marymount University Center for Optimal Aging (MCOA).
- Conditions
- Alzheimer Disease (AD), Cardio Vascular Disease, Mild Cognitive Impairment (MCI), Frailty Syndrome
- Trial name
- ALOHA (NCT07180147)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Marymount University
Metabolic Syndrome
Optimal Metabolic Health Through Continuous Glucose Monitoring
The primary focus of this study is to evaluate the role of Continuous Glucose Monitoring (CGM) with Levels Health software as a tool to provide feedback and accountability necessary to create sustainable behavioral changes in…
- Trial name
- CGM (NCT04920058)
- Testing
- Continuous Glucose Monitor, <Active Comparator?>
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Cardio Vascular Disease, Metabolic Syndrome (MetS)
Norwegian Mental Illness Heart Health Study
Norwegian patients with severe mental illnesses (SMI), such as schizophrenia spectrum or bipolar disorder, lose on average 10 years of life compared to mentally healthy individuals. Much of this gap is due to heart disease.
- Conditions
- Cardio Vascular Disease, Metabolic Syndrome (MetS), Severe Mental Disorder, Schizophrenia and Schizophrenia Spectrum Psychosis
- Trial name
- NORMI-Heart (NCT07085923)
- Testing
- Lifestyle Intervention
- Where
- Norway
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Madeleine Elisabeth Angelsen
Health Behavior, Genetic Information
The DNA-Based Lifestyle Enhancement Trial
Despite the known cardiovascular benefits of regular physical activity and having a balanced diet, it has proven challenging to change health behaviours towards favourable lifestyles.
- Conditions
- Health Behavior, Genetic Information, Cardiovascular Risk Factor
- Trial name
- DNAble (NCT03583983)
- Testing
- Personalized Health Recommendations, Generic Health Recommendations
- Where
- Canada
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Cardiometabolic Risk Factors
Effect of Probiotics on Cardiometabolic Health
Atherosclerosis is a major risk factor for cardiovascular diseases. Recently, dysbiosis of gut microbiota has been reported to play an important role in the pathogenesis of atherosclerosis.
- Trial name
- NCT05005754
- Testing
- Probiotics
- Where
- 2 sites in China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Cardiovascular Diseases, Heart Diseases
Improving Prevention of Heart Disease in Latinos
The purpose of the study is to improve cardiovascular disease (CVD) outcomes in racial and ethnic minorities. Specifically, it seeks to improve the primary prevention of CVD in Hispanics.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Diabetes Mellitus
- Trial name
- LUCHAR (NCT00101530)
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Diabetes (DM), Cardio Vascular Disease
Nut Consumption and Prevention of Non-communicable Diseases: A Global Individual Participant Data Meta-analysis
The relationship between nut consumption and the risk of developing non-communicable diseases (NCDs) has been a subject of growing interest.
- Conditions
- Diabetes (DM), Cardio Vascular Disease, Cancer, Dementia
- Trial name
- NUTPOOL (NCT07205978)
- Where
- 2 sites in Denmark, Spain
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili