Clinical trials: Cardiometabolic Diseases
Cardiometabolic Diseases, Multimorbidity
Health Chat for Empowerment-based Lifestyle Planning for Cardiometabolic Multimorbidity
The goal of this study is to: 1. assess the feasibility, acceptability, and the preliminary effects of the health chat for empowerment-based lifestyle planning for CMM (HcELP_CMM); 2.
- Trial name
- HcELP_CMM (NCT07158697)
- Testing
- HcELP_CMM, Usual Care
- Where
- 3 sites in China
- Volunteers
- 232 people
- Sponsor
- The University of Hong Kong
Metabolic Dysfunction-Associated Steatotic Liver Disease, Cardiometabolic Diseases
Impact of Circadian Exercise on Metabolic Dysfunction-Associated Steatotic Liver Disease in Postmenopausal Women
Type of Study: Clinical Trial Goal: The goal of this clinical trial is to investigate how performing exercise at different times of day (morning vs.
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Cardiometabolic Diseases, Exercise
- Trial name
- NCT07386665
- Testing
- Morning exercise group, Evening exercise group, Usual-care control group
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- Universidad de Almeria
Healthy Lifestyle, Home Environment Related Disease
HomeStyles-Adults of Chinese Heritage
Individuals of Chinese heritage are the largest and fastest growing segment of the US Asian population. US Chinese have sociodemographic characteristics and culture that differ substantially from other US Asians, and therefore…
- Conditions
- Healthy Lifestyle, Home Environment Related Disease, Cardiometabolic Disease, Systemic Inflammatory Response
- Trial name
- NCT06136793
- Testing
- HomeStyles-China
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Preeclampsia, Gestational Diabetes Mellitus (GDM)
Cardiometabolic Disease and Substrate Metabolism
This study's primary purpose is to determine the potential relationship between cardiometabolic disease, specifically insulin resistance (HOMA-IR), and maternal lipid oxidation.
- Conditions
- Preeclampsia, Gestational Diabetes Mellitus (GDM), Preeclampsia (PE), Preeclampsia (PE) Risk
- Trial name
- CAP (NCT07565727)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Tennessee Graduate School of Medicine
Hypertension (HTN), Cardiometabolic Diseases
Genetic Architecture of Natriuretic Peptides and Blood Pressure Response
Natriuretic peptides (NPs) are hormones produced by the heart and play an important role in maintaining cardiovascular health and have favorable metabolic benefits.
- Trial name
- NCT07118592
- Testing
- Low Salt Diet, High Salt Diet, Saline Infusion
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Kidney Diseases, Cardiometabolic Risk Factors
Feasibility Trial of a Stakeholder-enhanced Lay-navigator-delivered Intervention (ImPart-Multi)
The purpose is to explore the feasibility and acceptability of participation in a decision-support training program led by lay navigators.
- Trial name
- ImPart-Multi (NCT06067009)
- Testing
- ImPart-Multi - IMproving the decisional PARTnership of Chronic Kidney Disease Dyads with concurrent metabolic disease
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Alabama at Birmingham
Osteopenia, Cardiometabolic Conditions
Effects of Resistance Exercise Compared to Whole-body Electromyostimulation in Young Female Dentists.
Due to their high workload and unfavorable working position, young female dentists are particularly at risk of cardiometabolic diseases and an early reduction in bone mineral density (BMD).
- Trial name
- FeDeBoMa (NCT06813092)
- Testing
- Whole-Body Electromyostimulation, Resistance exercise
- Where
- 2 sites in Germany
- Volunteers
- 16 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Cystic Fibrosis Related Diabetes, Hyperglycaemia
Investigating the Relationship Between Glycemia and Sleep in Adults With Cystic Fibrosis-Related Diabetes
The goal of this at-home, remote study is to understand the relationship between blood sugars and sleep in adults living with Cystic Fibrosis Related Diabetes (CFRD).
- Conditions
- Cystic Fibrosis Related Diabetes, Hyperglycaemia, Insomnia, Cardiometabolic Diseases
- Trial name
- NCT06700889
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Type 2 Diabetes, Cardiometabolic Syndrome
PDE3B in Metabolic Regulation
Phosphodiesterase 3B (PDE3B), an enzyme responsible for the degradation of cyclic AMP and GMP (two important second messengers used for intracellular signal transduction), has been associated with cardiometabolic outcomes.
- Conditions
- Type 2 Diabetes, Cardiometabolic Syndrome, Cardiovascular Diseases
- Trial name
- NCT06533007
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Cardiometabolic Diseases, Noise Exposure
Impact of Earplugs on Mechanisms of Noise-Related Cardiovascular Disease
Noise from cars, planes, and trains affects all people and has been associated with heart disease. Almost 30% of Americans are exposed to harmful levels of noise and noise accounts for the loss of more than one million healthy…
- Trial name
- NCT07148817
- Testing
- Noise canceling earplugs, Usual care
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Massachusetts General Hospital
Cardiometabolic Syndrome, Physical Inactivity
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8…
- Conditions
- Cardiometabolic Syndrome, Physical Inactivity, Hypertension, Type 2 Diabetes
- Trial name
- NCT06055036
- Testing
- Black Impact Intervention
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- Ohio State University
Sarcopenia, Metabolic Diseases
Sarcopenia, Metabolic Diseases, and Integrated Aging Longitudinal Evaluation (SMILE)
This study aims to establish an ambispective cohort platform centered on the pathological axis of "sarcopenia-metabolic disorders-aging progression", integrating multimodal data including demographic characteristics, lifestyle…
- Conditions
- Sarcopenia, Metabolic Diseases, All-cause Mortality, Aging
- Trial name
- NCT07205510
- Testing
- nothing
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Cardiometabolic Diseases
Video Vitals and Biomarkers
The investigators are doing this research to study the ability of mobile devices to measure vital signs and biomarkers from video as compared to standard-of-care clinical office tools.
- Trial name
- NCT06136156
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- Maiv Health Inc.
Cardiometabolic Diseases
REal-world Data of CARdiometabolic ProtEcTion
This study is a single-center, historical prospective cohort study including patients diagnosed with metabolic cardiovascular disease, including hypertension, diabetes, obesity, dyslipidemia, hyperuricemia.
- Trial name
- RED-CARPET (NCT07038083)
- Where
- China
- Volunteers
- 40,000 people
- Sponsor
- Sun Yat-sen University
Cardiac Disease, Cardiovascular Diseases
Cardiometabolic Risk Factors and Processed Food
Cardiovascular diseases (CVD) remain a primary cause of chronic disability and mortality globally, with cardiometabolic risk factors such as hypertension, dyslipidemia, obesity, and diabetes significantly contributing to their…
- Conditions
- Cardiac Disease, Cardiovascular Diseases, Nutrition, Nutritional Disease
- Trial name
- NCT06996262
- Testing
- observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Sleep Disordered Breathing (SDB), Sleep Apnea
Sleep Disordered Breathing and Multimorbidity: The Xiangya SDB Cohort Study
Sleep disordered breathing (SDB) is one of the most common sleep disorders, including obstructive sleep apnea (OSA), central sleep apnea (CSA), sleep-related hypoventilation, hypoxemia, etc., with OSA being the most prevalent.
- Conditions
- Sleep Disordered Breathing (SDB), Sleep Apnea, Cardiometabolic Diseases, Multimorbidity
- Trial name
- NCT06755840
- Where
- China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Liver Functions, Bioequivalence
Coffee Bioequivalence Trial
The goal of this clinical trial is to test if coffee consumed as a tablet is biologically equivalent to that consumed traditionally as a drink.
- Conditions
- Liver Functions, Bioequivalence, Cardiovascular Risk, Cardiometabolic Risk Markers
- Trial name
- NCT06758531
- Testing
- Instant coffee given as a drink, Coffee given in a tablet form
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Reading
Cardiometabolic Syndrome, Cardiovascular Diseases
FINRISK 2002 Re-examination
The project aims to fill in the existing gaps in the study of the microbiome as a cardiometabolic driver 1) by determining the key demographic, environmental, genetic, dietary, and metabolic correlates of long-term…
- Trial name
- NCT06284772
- Testing
- Questionnaire and fecal sampling, Health examination
- Where
- Finland
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Turku
Heart Failure, Cardiometabolic Syndrome
Hyperpolarized MR Imaging with Carbon-13 Pyruvate in the Human Body
Positron emission tomography with 18F fluorodeoxyglucose (FDG) is the conventional imaging technique to provide information regarding tissue glucose uptake and has been highly clinically successful.
- Conditions
- Heart Failure, Cardiometabolic Syndrome, Cancer Diagnosis, Cardiovascular Diseases
- Trial name
- POLARIC-13 (NCT06645691)
- Testing
- Hyperpolarized 13C-pyruvate
- Where
- Singapore
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Abdominal Obesity, Cardiac Disease
Effects of Different Dietary Interventions on Abdominal Fat Components, Quadriceps Muscles and Cardiometabolic Parameters
The study aims to evaluate the impact of different dietary interventions on body composition (abdominal fat components and quadriceps muscles) and cardiometabolic parameters.
- Conditions
- Abdominal Obesity, Cardiac Disease, Metabolic Disease, Cardiometabolic Syndrome
- Trial name
- NCT06320782
- Testing
- Calorie restriction and balanced distribution of macronutrients, Calorie restriction and low-carbohydrate diet, Calorie restriction and low-fat diet
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pernambuco